Spaceline/NASA Space Life Science Current Awareness – March 2000
Recent scientific publications of investigators whose research derives
from support of the Life Sciences Division of NASA are listed below.
The Principal Investigator or PI is noted. The lists are compiled weekly,
and a new list is added each week.
1
AU – Schatten H ; Ripple M ; Balczon R ; Weindruch R ; Chakrabarti A ; Taylor
M ; Hueser CN
TI – Androgen and taxol cause cell type-specific alterations of centrosome and
DNA organization in androgen-responsive LNCaP and androgen-independent
DU145 prostate cancer cells.
SO – J Cell Biochem. 2000 Jan;76(3):463-77.
(PI: H. Schatten)
2
AU – Zhou HN ; Randers-Pehrson G ; Waldren CA ; Vannais D ; Hall EJ ; Hei TK
TI – Induction of a bystander mutagenic effect of alpha particles in mammalian
cells.
SO – Proc Natl Acad Sci U S A 2000 Feb 29;97(5):2099-104.
(PIs: C.A. Waldren and A. Chatterjee: NSCORT in Radiation Health)
3
AU – Kiss JZ ; Brinckmann E ; Brillouet C
TI – Development and growth of several strains of Arabidopsis seedlings in
microgravity.
SO – Int J Plant Sci 2000 Jan;161(1):55-62.
(PI: J.Z. Kiss)
4
AU – Tittel FK ; Lancaster DG ; Richter D
TI – Novel diode laser-based sensors for gas sensing applications.
SO – Laser Phys 2000 Jan-Feb;10(1):348-54.
(PI: F.K. Tittel)
5
AU – Knee EM ; Hangarter RP ; Knee M
TI – Interactions of light and ethylene in hypocotyl hook maintenance in
Arabidopsis thaliana seedlings.
SO – Physiol Plant 2000 Feb;108(2):208-15.
(PI: R.P. Hangarter)
6
AU – Lewis ML ; Hughes-Fulford M
TI – Regulation of heat shock protein message in Jurkat cells cultured under
serum-starved and gravity-altered conditions.
SO – J Cell Biochem 2000 Apr;77(1):127-134.
(PIs: M.L. Lewis and M. Hughes-Fulford)
7
AU – Harris SA ; Zhang M ; Kidder LS ; Evans GL ; Spelsberg TC ; Turner RT
TI – Effects of orbital spaceflight on human osteoblastic cell physiology and
gene expression.
SO – Bone 2000 Apr;26(4):325-31.
(PI: R.T. Turner)
1
AU – Lisle JT ; Stewart PS ; McFeters GA
TI – Fluorescent probes applied to physiological characterization of bacterial
biofilms.
SO – Methods Enzymol 1999;310:166-78.
(PI: G.A. McFeters)
2
AU – Masseguin C ; Corcoran M ; Carcenac C ; Daunton NG ; Guell A ;
Verkman AS ; Gabrion J
TI – Altered gravity downregulates aquaporin-1 protein expression in choroid
plexus.
SO – J Appl Physiol 2000 Mar;88(3):843-50.
(PI: N.G. Daunton)
3
AU – Adams GR ; McCue SA ; Bodell PW ; Zeng M ; Baldwin KM
TI – Effects of spaceflight and thyroid deficiency on rat hindlimb development.
I. muscle mass and IGF-I expression.
SO – J Appl Physiol 2000 Mar;88(3):894-903.
(PIs: G.R. Adams and K.M. Baldwin)
4
AU – Adams GR ; Haddad F ; McCue SA ; Bodell PW ; Zeng M ; Qin L ; Qin AX
; Baldwin KM
TI – Effects of spaceflight and thyroid deficiency on rat hindlimb development.
II. expression of MHC isoforms.
SO – J Appl Physiol 2000 Mar;88(3):904-16.
(PIs: G.R. Adams and K.M. Baldwin)
5
AU – Muenter NK ; Watenpaugh DE ; Wasmund WL ; Wasmund SL ; Maxwell SA
; Smith ML
TI – Effect of sleep restriction on orthostatic cardiovascular control in humans.
SO – J Appl Physiol 2000 Mar;88(3):966-72.
(PIs: N.K. Muenter and M.L. Smith)
6
AU – Mure M ; Domino KB ; Lindahl SG ; Hlastala MP ; Altemeier WA ;
Glenny RW
TI – Regional ventilation-perfusion distribution is more uniform in the prone
position.
SO – J Appl Physiol 2000 Mar;88(3):1076-83.
(PI: M.P. Hlastala)
7
AU – Stein TP ; Leskiw MJ
TI – Oxidant damage during and after spaceflight.
SO – Am J Physiol Endocrinol Metab 2000 Feb;278(2):E375-82.
(PI: T.P. Stein)
8
AU – Crippa GE ; Lewis SJ ; Johnson AK ; Correa FM
TI – Medial prefrontal cortex acetylcholine injection-induced hypotension: the
role of hindlimb vasodilation.
SO – J Auton Nerv Syst 2000 Feb 14;79(1):1-7.
(PI: A.K. Johnson)
9
AU – Furlan R ; Porta A ; Costa F ; Tank J ; Baker L ; Schiavi R ; Robertson D ;
Malliani A ; Mosqueda-Garcia R
TI – Oscillatory patterns in sympathetic neural discharge and cardiovascular
variables during orthostatic stimulus.
SO – Circulation 2000 Feb 29;101(8):886-892.
(PI: D. Robertson)
10
AU – Jin S ; Shimizu M ; Balasubramanyam A ; Epstein HF
TI – Myotonic dystrophy protein kinase (DMPK) induces actin cytoskeletal
reorganization and apoptotic-like blebbing in lens cells.
SO – Cell Motil Cytoskeleton 2000 Feb;45(2):133-48.
(PI: H.F. Epstein)
11
AU – Butel JS ; Jafar S ; Wong C ; Arrington AS ; Opekun AR ; Finegold MJ ;
Adam E
TI – Evidence of SV40 infections in hospitalized children.
SO – Hum Pathol 1999 Dec;30(12):1496-502.
(PI: J.S. Butel)
1
AU – Dangott B ; Schultz E ; Mozdziak PE
TI – Dietary creatine monohydrate supplementation increases satellite cell
mitotic activity during compensatory hypertrophy.
SO – Int J Sports Med. 2000 Jan;21(1):13-6.
(PI: E. Schultz)
2
AU – Cosgrove DJ
TI – New genes and new biological roles for expansins.
RF – REVIEW ARTICLE: 44 REFS.
SO – Curr Opin Plant Biol. 2000 Feb;3(1):73-8.
(PI: D.J. Cosgrove)
3
AU – Tabata T ; Oki T ; Yamada H ; Abe M ; Onose Y ; Thomas JD
TI – Subendocardial motion in hypertrophic cardiomyopathy: assessment from
long- and short-axis views by pulsed tissue Doppler imaging.
SO – J Am Soc Echocardiogr 2000 Feb;13(2):108-15.
(PI: J.D. Thomas)
4
AU – Curtis SB ; Vazquez ME ; Wilson JW ; Atwell W ; Kim MH
TI – Cosmic ray hits in the central nervous system at solar maximum.
SO – Adv Space Res 2000;25(10):2035-40.
(PIs: S.B. Curtis and J.W. Wilson)
5
AU – Joseph JA ; Shukitt-Hale B ; McEwen J ; Rabin BM
TI – CNS-induced deficits of heavy particle irradiation in space: the aging
connection.
SO – Adv Space Res 2000;25(10):2057-64.
(PI: B.M. Rabin)
6
AU – Rabin BM ; Joseph JA ; Shukitt-Hale B ; McEwen J
TI – Effects of exposure to heavy particles on a behavior mediated by the
dopaminergic system.
SO – Adv Space Res 2000;25(10):2065-74.
(PI: B.M. Rabin)
7
AU – Yang TC ; Craise LM ; Raju MR
TI – Oncogenic transformation of mammalian cells by ultrasoft x-rays and
alpha particles.
SO – Adv Space Res 2000;25(10):2123-30.
(PI: T.C. Yang)
8
AU – Cucinotta F ; Dicello JF
TI – On the development of biophysical models for space radiation risk
assessment.
SO – Adv Space Res 2000;25(10):2131-40.
(PIs: J.F. Dicello and J.W. Wilson)
9
AU – Morehead AJ ; Firstenberg MS ; Shiota T ; Qin J ; Armstrong G ; Cosgrove
DM 3rd ; Thomas JD
TI – Intraoperative echocardiographic detection of regurgitant jets after
valve replacement.
SO – Ann Thorac Surg 2000 Jan;69(1):135-9.
(PI: J.D. Thomas)
10
AU – Mosier DR ; Siklos L ; Appel SH
TI – Resistance of extraocular motoneuron terminals to effects of amyotrophic
lateral sclerosis sera.
SO – Neurology 2000 Jan 11;54(1):252-5.
(PI: D.R. Mosier)
11
TI – Nutrition in spaceflight and weightlessness models (edited by Helen W.
Lane, Dale A. Schoeller).
SO – Boca Raton, FL : Lewis Publishers, 2000. 301 p. : ill. (CRC series in
modern nutrition)
(PIs: H.W. Lane and D.A. Schoeller)
12
AU – Smit AA ; Wieling W ; Opfer-Gehrking TL ; van Emmerik-Levelt HM ; Low PA
TI – Patient’s choice of portable folding chairs to reduce symptoms of orthostatic
hypotension.
SO – Clin Auton Res 1999 Dec;9(6):341-4.
(PI: P.A. Low)
13
AU – Telford WG ; Cox WG ; Stiner D ; Singer VL ; Doty SB
TI – Detection of endogenous alkaline phosphatase activity in intact cells by flow
cytometry using the fluorogenic ELF-97 phosphatase substrate.
SO – Cytometry 1999 1 Dec;37(4):314-9.
(PI: S.B. Doty)
14
AU – Knierim JJ ; McNaughton BL ; Poe GR
TI – Three-dimensional spatial selectivity of hippocampal neurons during space
flight.
SO – Nat Neurosci 2000 Mar;3(3):209-10.
(PI: B.L. McNaughton)
1
AU – Kahwaji CI ; Sangha DS ; Sheibani S ; Ashori M ; Nguyen H ; Kim Y ; Purdy
RE
TI – Simulated microgravity-induced vascular hyporesponsiveness: role of
signal transduction.
SO – Proc West Pharmacol Soc 1999;42:9-12.
(PI: R.E. Purdy)
2
AU – Sangha DS ; Vaziri ND ; Ding Y ; Han S ; Alem N ; Chen YA ; Purdy RE
TI – Simulated microgravity impairs vascular contractility: role of nitric
oxide-dependent vasodilator mechanisms.
SO – Proc West Pharmacol Soc 1999;42:5-7.
(PI: R.E. Purdy)
3
AU – Booth FW ; Gordon SE ; Carlson CJ ; Hamilton MT
TI – Waging war on modern chronic diseases: primary prevention through
exercise biology.
SO – J Appl Physiol 2000 Feb;88(2):774-87.
(PI: F.W. Booth)
4
AU – di Maso NA ; Haddad F ; Zeng M ; McCue SA ; Baldwin KM
TI – Role of denervation in modulating IIb MHC gene expression in response to
T(3) plus unloading state.
SO – J Appl Physiol 2000 Feb;88(2):682-9.
(PI: K.M. Baldwin)
5
AU – Roach RC ; Maes D ; Sandoval D ; Robergs RA ; Icenogle M ;
Hinghofer-Szalkay H ; Lium D ; Loeppky JA
TI – Exercise exacerbates acute mountain sickness at simulated high altitude.
SO – J Appl Physiol 2000 Feb;88(2):581-5.
(PI: J.A. Loeppky)
6
AU – Riley DA ; Bain JL ; Thompson JL ; Fitts RH ; Widrick JJ ; Trappe SW ;
Trappe TA ; Costill DL
TI – Decreased thin filament density and length in human atrophic soleus
muscle fibers after spaceflight.
SO – J Appl Physiol 2000 Feb;88(2):567-72.
(PIs: D.A. Riley and R.H. Fitts)
7
AU – Sangha DS ; Vaziri ND ; Ding Y ; Purdy RE
TI – Vascular hyporesponsiveness in simulated microgravity: role of nitric
oxide-dependent mechanisms.
SO – J Appl Physiol 2000 Feb;88(2):507-17.
(PI: R.E. Purdy)
8
AU – Grichko VP ; Heywood-Cooksey A ; Kidd KR ; Fitts RH
TI – Substrate profile in rat soleus muscle fibers after hindlimb unloading
and fatigue.
SO – J Appl Physiol 2000 Feb;88(2):473-8.
(PI: R.H. Fitts)
9
AU – Huckstorf BL ; Slocum GR ; Bain JL ; Reiser PM ; Sedlak FR ;
Wong-Riley MT ; Riley DA
TI – Effects of hindlimb unloading on neuromuscular development of neonatal
rats.
SO – Brain Res Dev Brain Res. 2000 Feb 7;119(2):169-178.
(PI: D.A. Riley)
10
AU – Rhoten WB ; Sergeev IN ; Chaudhry MA
TI – Calbindins, insulin and apoptosis in Neurolab tissues (abstract)
SO – Mol Biol Cell 1999 Nov;10(Suppl):48a.
(PI: W.B. Rhoten)
1
AU – Shannon JR ; Flattem NL ; Jordan J ; Jacob G ; Black BK ; Biaggioni I ;
Blakely RD ; Robertson D
TI – Orthostatic intolerance and tachycardia associated with
norepinephrine-transporter deficiency.
SO – N Engl J Med. 2000 Feb 24;342(8):541-9.
(PIs: D. Robertson and I. Biaggioni)
2
AU – Jordan J ; Shannon JR ; Black BK ; Ali Y ; Farley M ; Costa F ; Diedrich
A ; Robertson RM ; Biaggioni I ; Robertson D
TI – The pressor response to water drinking in humans : a sympathetic reflex?
SO – Circulation. 2000 Feb 8;101(5):504-9.
(PIs: D. Robertson and I. Biaggioni)
3
AU – Rhoads DN ; Eskin SG ; McIntire LV
TI – Fluid flow releases fibroblast growth factor-2 from human aortic smooth
muscle cells.
SO – Arterioscler Thromb Vasc Biol 2000 Feb;20(2):416-21
(PI: L.V. McIntire: NSCORT in Gravitational Biology)
4
AU – Yang T ; Poovaiah BW
TI – Molecular and biochemical evidence for the involvement of
calcium/calmodulin in auxin action.
SO – J Biol Chem 2000 Feb 4;275(5):3137-43
(PI: B.W. Poovaiah)
5
AU – Vashishth D ; Koontz J ; Qiu SJ ; Lundin-Cannon D ; Yeni YN ; Schaffler
MB ; Fyhrie DP
TI – In vivo diffuse damage in human vertebral trabecular bone.
SO – Bone 2000 Feb;26(2):147-52
(PI: M.B. Schaffler)
6
AU – Sandroni P ; Novak V ; Opfer-Gehrking TL ; Huck CA ; Low PA
TI – Mechanisms of blood pressure alterations in response to the Valsalva
maneuver in postural tachycardia syndrome.
SO – Clin Auton Res 2000 Feb;10(1):1-5.
(PI: P.A. Low)
7
AU – Gordon VM ; Opfer-Gehrking TL ; Novak V ; Low PA
TI – Hemodynamic and symptomatic effects of acute interventions on tilt in
patients with postural tachycardia syndrome.
SO – Clin Auton Res 2000 Feb;10(1):29-33.
(PI: P.A. Low)
8
AU – Sawka MN ; Convertino VA ; Eichner ER ; Schneider SM ; Young AJ
TI – Blood volume: importance and adaptations to exercise training,
environmental stresses, and trauma/sickness.
SO – Med Sci Sports Exerc 2000 Feb;32(2):332-48
(PIs: V.A. Convertino and S.M. Schneider)
Note: Article includes a section on space flight/microgravity.
9
AU – Alberts JR ; Ronca AE
TI – Effects of gravity on development: the importance of behavior.
SO – J Gravit Physiol 1999 Jul;6(1):P5-8.
(PI: J.R. Alberts)
10
AU – Davies E ; Shimps B ; Brown K ; Stankovic B
TI – Gravity, stress, calcium and gene expression.
SO – J Gravit Physiol 1999 Jul;6(1):P21-22.
(PI: E. Davies: NSCORT in Plant Biology)
11
AU – Crucian BE ; Sams CF
TI – The use of a spaceflight-compatible device to perform WBC surface
marker staining and whole blood mitogenic activation for cytokine detection
by flow cytometry.
SO – J Gravit Physiol 1999 Jul;6(1):P33-34.
(PI: C.F. Sams)
12
AU – Holstein GR ; Kukielka E ; Martinelli GP
TI – Anatomical observations of the rat cerebellar nodulus after 24 hr of
spaceflight.
SO – J Gravit Physiol 1999 Jul;6(1):P47-50.
(PI: G.R. Holstein)
13
AU – Robertson D ; Biaggioni I ; Ertl AC ; Robertson RM ; Diedrich A ;
Blakely RD ; Flattem N ; Shannon JR
TI – Orthostatic intolerance: emerging genetic and environmental etiologies.
SO – J Gravit Physiol 1999 Jul;6(1):P51-54.
(PIs: D. Robertson and I. Biaggioni)
14
AU – Convertino VA
TI – G factor as a tool in basic research: the mechanisms of orthostatic
intolerance.
SO – J Gravit Physiol 1999 Jul;6(1):P73-76.
(PI: V.A. Convertino)
15
AU – Stein TP ; Schluter MD ; Leskiw MJ
TI – Cortisol, insulin and leptin during space flight and bed rest.
SO – J Gravit Physiol 1999 Jul;6(1):P85-86.
(PIs: T.P. Stein and M.D. Schluter)
16
AU – Whitson PA ; Pietrzyk RA ; Sams CF
TI – Space flight and the risk of renal stones.
SO – J Gravit Physiol 1999 Jul;6(1):P87-88.
(PIs: P.A. Whitson and C.F. Sams)
17
AU – Doty SB ; Stiner D ; Telford WG
TI – The effect of spaceflight on cartilage cell cycle and differentiation.
SO – J Gravit Physiol 1999 Jul;6(1):P89-90.
(PI: S.B. Doty)
18
AU – Schatten H ; Zoran S ; Levine HG ; Anderson K ; Chakrabarti A
TI – Sea urchin fertilization during a KC-135 parabolic flight.
SO – J Gravit Physiol 1999 Jul;6(1):P91-92.
(PI: H. Schatten)
19
AU – Jiao S ; Hilaire E ; Paulsen AQ ; Guikema JA
TI – Ultrastructural observation of altered chloroplast morphology in
space-grown Brassica rapa cotyledons.
SO – J Gravit Physiol 1999 Jul;6(1):P93-94.
(PI: J.A. Guikema)
20
AU – Adamchuk NI ; Mmikhaylenko NF ; Zolotareva EK ; Hilaire E ; Guikema JA
TI – Spaceflight effects on structural and some biochemical parameters of
Brassica rapa photosynthetic apparatus.
SO – J Gravit Physiol 1999 Jul;6(1):P95-96.
(PI: J.A. Guikema)
21
AU – Klymchuk DO ; Brown CS ; Chapman D
TI – Ultrastructural organization of cells in soybean root tips in
microgravity.
SO – J Gravit Physiol 1999 Jul;6(1):P97-98.
(PI: C.S. Brown)
22
AU – Miller MS ; Keller TS
TI – Measuring Drosophila (fruit fly) activity during microgravity exposure.
SO – J Gravit Physiol 1999 Jul;6(1):P99-100.
(PI: M.S. Miller)
23
AU – Kordyum EI ; Martin GI ; Zaslavsky VA ; Jiao S ; Hilaire E ; Guikema JA
TI – DNA content and differentiation of root apical cells of Brassica rapa
plants grown in microgravity.
SO – J Gravit Physiol 1999 Jul;6(1):P119-120.
(PIs: M.E. Musgrave and J.A. Guikema)
24
AU – Nedukha OM ; Brown CS ; Kordyum E ; Piastuch WC
TI – Electron-cytochemical study of Ca++ in cotyledon cells of soybean
seedlings grown in microgravity.
SO – J Gravit Physiol 1999 Jul;6(1):P123-124.
(PIs: C.S. Brown and J.A. Guikema)
25
AU – Nedukha OM ; Leach J ; Kordyum E ; Ryba-White M ; Hilaire E ; Guikema
J ; Piastuch W
TI – Root meristem ultrastructure of soybean seedlings infected with a
pathogenic fungus in microgravity.
SO – J Gravit Physiol 1999 Jul;6(1):P125-126.
(PI: J. Leach)
26
AU – Volovik OI ; Kordyum EI ; Guikema JA
TI – Some characteristics of photosynthetic apparatus under conditions of
spaceflight.
SO – J Gravit Physiol 1999 Jul;6(1):P127-128.
(PI: J.A. Guikema)
27
AU – Monk T
TI – Aging and space flight: findings from the University of Pittsburgh.
SO – J Gravit Physiol 1999 Jul;6(1):P137-140.
(PI: T. Monk)
28
AU – Putcha L
TI – Pharmacotherapeutics in space.
SO – J Gravit Physiol 1999 Jul;6(1):P165-168.
(PI: L. Putcha)
Note: 53 other papers not authored by NASA PIs are also in this issue.
