Spaceline/NASA Space Life Science Current Awareness – 21 December 2001

1
Cucinotta FA, Nikjoo H. (editors)
Models for evaluation of radiation risk factors.
Radiat Res. 2001 Nov;156(5 Pt 2):571-694.
(PI: F.A. Cucinotta)
NOTE: This issue includes papers from the workshop “Models for Evaluation of Radiation Risk Factors,” which took place in Houston, Texas, November 12-15, 2000. The workshop reviewed radiation risk models to identify critical parameters and focus areas for predicting the risk to humans from ionizing radiation, with a goal of planning safer space travel, as well as radiation protection on Earth. Seven NASA-supported papers from this issue are listed below; selected papers are listed in the “other papers of interest” section.

2
Cucinotta FA, Schimmerling W, Wilson JW, Peterson LE, Badhwar GD, Saganti PB,
Dicello JF.
Space radiation cancer risks and uncertainties for Mars missions.
Radiat Res. 2001 Nov;156(5 Pt 2):682-8.
(PIs: F.A. Cucinotta, J.W. Wilson, G.D. Badhwar and J.F. Dicello)

3
Durante M, Bonassi S, George K, Cucinotta FA.
Risk estimation based on chromosomal aberrations induced by radiation.
Radiat Res. 2001 Nov;156(5 Pt 2):662-7.
(PI: F.A. Cucinotta)

4
Carnes BA, Gavrilova N.
Risk analysis: divergent models and convergent interpretations.
Radiat Res. 2001 Nov;156(5 Pt 2):628-30.
(PI: B.A. Carnes)

5
Barcellos-Hoff MH, Brooks AL.
Extracellular signaling through the microenvironment: a hypothesis relating
carcinogenesis, bystander effects, and genomic instability.
Radiat Res. 2001 Nov;156(5 Pt 2):618-27.
(PIs: A.L. Brooks; M.H. Barcellos-Hoff and A. Chatterjee: NSCORT in Radiation Health)

6
Wu H.
Probabilities of radiation-induced inter- and intrachromosomal exchanges and
their dependence on the DNA content of the chromosome.
Radiat Res. 2001 Nov;156(5 Pt 2):603-6.
(PI: T.C. Yang)

7
Kawata T, Durante M, Furusawa Y, George K, Ito H, Wu H, Cucinotta FA.
Rejoining of isochromatid breaks induced by heavy ions in G2-phase normal human
fibroblasts.
Radiat Res. 2001 Nov;156(5 Pt 2):598-602.
(PI: F.A. Cucinotta)

8
Ponomarev AL, Cucinotta FA, Sachs RK, Brenner DJ, Peterson LE.
Extrapolation of the DNA fragment-size distribution after high-dose irradiation
to predict effects at low doses.
Radiat Res. 2001 Nov;156(5 Pt 2):594-7.
(PI: F.A. Cucinotta)

9
Cucinotta FA, Manuel FK, Jones J, Iszard G, Murrey J, Djojonegro B, Wear M.
Space radiation and cataracts in astronauts.
Radiat Res. 2001 Nov;156(5 Pt 1):460-6.
(PI: F.A. Cucinotta)

10
Costes S, Sachs R, Hlatky L, Vannais D, Waldren C, Fouladi B.
Large-mutation spectra induced at hemizygous loci by low-LET radiation: evidence
for intrachromosomal proximity effects.
Radiat Res. 2001 Nov;156(5 Pt 1):545-57.
(PIs: C. Waldren and A. Chatterjee: NSCORT in Radiation Health)

11
Brenner DJ, Elliston CD.
The potential impact of bystander effects on radiation risks in a Mars mission.
Radiat Res. 2001 Nov;156(5 Pt 2):612-7.
(PI: E.J. Hall)

12
Go YM, Levonen AL, Moellering D, Ramachandran A, Patel RP, Jo H, Darley-Usmar
VM.
Endothelial NOS-dependent activation of c-Jun NH(2)-terminal kinase by oxidized
low-density lipoprotein.
Am J Physiol Heart Circ Physiol. 2001 Dec;281(6):H2705-13.
(PI: H. Jo)

13
Kourentzi KD, Fox GE, Willson RC.
Microbial detection with low molecular weight RNA.
Curr Microbiol. 2001 Dec;43(6):444-7.
(PI: G.E. Fox)

14
Choe SY, Neudeck BL, Welage LS, Amidon GE, Barnett JL, Amidon GL.
Novel method to assess gastric emptying in humans: the Pellet Gastric Emptying
Test.
Eur J Pharm Sci. 2001 Dec;14(4):347-53.
(PI: G.L. Amidon)

15
Czarny O, Serre E, Bontoux P, Lueptow RM.
Identification of complex flows in Taylor-Couette counter-rotating cavities.
C R Acad Sci II Fasc B. 2001 Oct;329(10):727-33.
(PI: R.M. Lueptow)

16
Mortley DG, Hill JH, Hileman DR, Bonsi CK, Hill WA.
Light and CO2 interaction on peanut grown in nutrient film technique.
Acta Hortic. 2001;548:327-31.
(PI: D.G. Mortley)

17
Mortley DG, Bonsi CK, Hill JH, Hill WA.
Nutrient management of sweetpotato grown in nutrient film technique.
Acta Hortic. 2001;548:567-73.
(PI: D.G. Mortley)

18
Schettino G, Folkard M, Prise KM, Vojnovic B, Bowey AG, Michael BD.
Low-dose hypersensitivity in Chinese hamster V79 cells targeted with counted
protons using a charged-particle microbeam.
Radiat Res. 2001 Nov;156(5 Pt 1):526-34.

19
Scholz M, Jakob B, Taucher-Scholz G.
Direct evidence for the spatial correlation between individual particle
traversals and localized CDKN1A (p21) response induced by high-LET radiation.
Radiat Res. 2001 Nov;156(5 Pt 1):558-63.

20
Prise KM, Pinto M, Newman HC, Michael BD.
A review of studies of ionizing radiation-induced double-strand break
clustering.
Radiat Res. 2001 Nov;156(5 Pt 2):572-6.

21
Nikjoo H, O’Neill P, Wilson WE, Goodhead DT.
Computational approach for determining the spectrum of DNA damage induced by
ionizing radiation.
Radiat Res. 2001 Nov;156(5 Pt 2):577-83.

22
Weinfeld M, Rasouli-Nia A, Chaudhry MA, Britten RA.
Response of base excision repair enzymes to complex DNA lesions.
Radiat Res. 2001 Nov;156(5 Pt 2):584-9.

23
Jenner TJ, Fulford J, O’Neill P.
Contribution of base lesions to radiation-induced clustered DNA damage:
implication for models of radiation response.
Radiat Res. 2001 Nov;156(5 Pt 2):590-3. Review.

24
Kiefer J, Schmidt P, Koch S.
Mutations in mammalian cells induced by heavy charged particles: an indicator
for risk assessment in space.
Radiat Res. 2001 Nov;156(5 Pt 2):607-11.

25
Amundson SA, Bittner M, Meltzer P, Trent J, Fornace AJ.
Induction of gene expression as a monitor of exposure to ionizing radiation.
Radiat Res. 2001 Nov;156(5 Pt 2):657-61.

26
McCarthy TL, Centrella M.
Local IGF-I expression and bone formation.
Growth Horm IGF Res. 2001 Aug;11(4):213-9.

27
Tobal N, Roumy J, Herault S, Fomina G, Arbeille P.
Doppler measurement of cerebral and lower limb flow during a lower body negative
pressure test for predicting orthostatic intolerance.
J Ultrasound Med. 2001;20(11):1207-17.

28
Nelson JN, Alsajir MB.
Tele-education–postgraduate education.
Med Princ Pract. 2001;10(3):115-22.

29
Hu Z, Liu Y, Tu H.
[Effect of microgravity simulation with clinostat on different strains in Anabaena
oryza]
Weishengwu Xuebao. 2001 Aug;41(4):489-93. Chinese.

30
Commissaris DA, Nieuwenhuijzen PH, Overeem S, de Vos A, Duysens JE, Bloem BR.
Dynamic posturography using a new movable multidirectional platform driven by
gravity.
J Neurosci Methods. 2002 Jan 15;113(1):73-84.

31
Stankovic B.
2001: a plant space odyssey.
Trends Plant Sci. 2001 Dec 1;6(12):591-3.

32
Timpte C.
Auxin binding protein: curiouser and curiouser.
Trends Plant Sci. 2001 Dec 1;6(12):586-90.

33
Migliaccio F, Piconese S.
Spiralizations and tropisms in Arabidopsis roots.
Trends Plant Sci. 2001 Dec 1;6(12):561-5.