NASA Spaceline Current Awareness List #992 25 March 2022 (Space Life Science Research Results)

 

Call for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an article that has recently published or will publish in the upcoming weeks within a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your article to the email address mentioned above. Articles received by Wednesday will appear within that week’s list—articles received after Wednesday will appear the following week.

 

Papers deriving from NASA support:

 

1

Scott JM, Stoudemire J, Dolan L, Downs M.

Circ Res. 2022 Mar 17;130(6):942-57. Review.

Note: From the abstract: “In this review, we provide a historical overview of research evaluating the effects of spaceflight on cardiovascular health in astronauts and outline mechanisms underpinning spaceflight-related cardiovascular alterations.”

Journal Impact Factor: 17.37

Funding: “This work is supported by the National Aeronautics and Space Administration (NASA) Human Research Program, the Memorial Sloan Kettering Cancer Center Support Grant/Core Grant (P30 CA008748), and the National Cancer Institute of the National Institutes of Health under Award Number R37CA248665 (J.M. Scott). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.”

 

2

Tays GD, McGregor HR, Lee JK, Beltran N, Kofman IS, De Dios YE, Mulder E, Bloomberg JJ, Mulavara AP, Wood SJ, Seidler RD.

Front Neural Circuits. 2022 Mar 2;16:784280.

PI: R.D. Seidler

Note: Head-down tilt bedrest and short-arm human centrifuge results. This article is part of Research Topic “Brains in Space: Effects of Spaceflight on the Human Brain and Behavior” (https://www.frontiersin.org/research-topics/19134/brains-in-space-effects-of-spaceflight-on-the-human-brain-and-behavior#articles). The Research Topic also includes articles from previous Current Awareness Lists #956 https://doi.org/10.3389/fncir.2021.659557; #967 https://doi.org/10.3389/fphys.2021.654906; #969 https://doi.org/10.3389/fphys.2021.746509; #973 https://doi.org/10.3389/fncir.2021.723504; #975 https://doi.org/10.3389/fncir.2021.757817, https://doi.org/10.3389/fncir.2021.760313, and https://doi.org/10.3389/fphys.2021.750414; #976 https://doi.org/10.3389/fphys.2021.770502; #977 https://doi.org/10.3389/fphys.2021.782860; #979 https://doi.org/10.3389/fncir.2021.750176; #982 https://doi.org/10.3389/fphys.2021.795321; #985 https://doi.org/10.3389/fphys.2022.806357; #987 https://doi.org/10.3389/fphys.2021.751016; #988 https://doi.org/10.3389/fncir.2022.815838; and #991 https://doi.org/10.3389/fphys.2022.743855. This article may be obtained online without charge.

Journal Impact Factor: 3.492

Funding: “This work was supported by grants from the National Aeronautics and Space Administration (NASA 80NSSC18K0783) to RS, AM, SW, and JB. During the completion of this work GT was supported by the University of Florida’s (UF) Graduate Student Funding Award and by NIH T32-NS082128. HM was supported by a Natural Sciences and Engineering Research Council of Canada (NSERC) Postdoctoral Fellowship and a NASA Human Research Program Augmentation Grant.”

 

3

Mehta A, Vasquez N, Ayers CR, Patel J, Hooda A, Khera A, Blumenthal RS, Shapiro MD, Rodriguez CJ, Tsai MY, Sperling LS, Virani SS, Blaha MJ, Joshi PH.

J Am Coll Cardiol. 2022 Mar 1;79(8):757-68.

Note: An article below in the “Other” section by S. Tsimikas is an editorial comment to this article.

Journal Impact Factor: 24.094

Funding: “…Dr. Joshi has received grant support from the American Heart Association, NASA, and Novo Nordisk; has received consulting income from Bayer and Regeneron; owns equity in G3 Therapeutics; and has served as a site investigator with all funds to the institution from GlaxoSmithKline, Sanofi, AstraZeneca, and Novartis.”

 

4

Lam CW, Castranova V, Zeidler-Erdely PC, Renne R, Hunter R, McCluskey R, Scully RR, Wallace WT, Zhang Y, Ryder VE, Cooper B, McKay D, McClellan RO, Driscoll KE, Gardner DE, Barger M, Meighan T, James JT.

Inhal Toxicol. 2022 Mar 16;1-17. Online ahead of print.

PI: C.W. Lam

Journal Impact Factor: 2.300

Funding: “This lunar dust ITI toxicity study and the follow-up LD Inhalation toxicity study (Lam et al., 2013) were the two major parts of the multi-year project funded by the NASA Human Research Program Grant through NASA’s Johnson Space Center and Wyle Bioastronautics Contract #NAS9-02078.”

 

5

Sanchez ZAC, Vijayananda V, Virassammy DM, Rosenfeld L, Ramasubramanian AK.

Biomicrofluidics. 2022 Mar 3;16(2):024103.

PI: A.K. Ramasubramanian

Journal Impact Factor: 2.800

Funding: “The authors acknowledge the financial support from NASA (No. 80NSSC21K0272), National Science Foundation (NSF) (No. 1727072), and volunteer blood donors, and technical assistance from Dr. Alfred Renaldo at MPEL, SJSU.”

 

6

Ronaldson-Bouchard K, Baldassarri I, Naveed Tavakol D, Graney PL, Samaritano M, Cimetta E, Vunjak-Novakovic G.

Adv Drug Deliv Rev. 2022 May;184:114181. Review.

PI: G. Vunjak-Novakovic

Journal Impact Factor: 15.470

Funding: “Studies described in this review are funded by NIH (grants R01 CA249799, UH3 EB025765 and P41 EB027062 to GVN), NASA (grant NNX16AO69A to GVN), NSF (Graduate Research Fellowship DGE1644869 to DNT) and ASPR-BARDA (grant 75A50121C00017 to GVN). European Research Council (ERC StG-UERI17, to EC).”

 

7

Brown TM, Brainard GC, Cajochen C, Czeisler CA, Hanifin JP, Lockley SW, Lucas RJ, Münch M, O’Hagan JB, Peirson SN, Price LLA, Roenneberg T, Schlangen LJM, Skene DJ, Spitschan M, Vetter C, Zee PC, Wright KP Jr.

PLoS Biol. 2022 Mar 17;20(3):e3001571.

PI: G.C. Brainard

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “GCB was supported, in part, by DOE grant DE- EE0008207, NAS Award #HR 05-23 UNIT 905; NASA grant NNX15AC14G; the NSF ERC LESA Center; BIOS, Toshiba Material science, The Nova Institute (The Institute for Integrative Health) and the Philadelphia Section of the Illuminating Engineering Society. …CAC reports grants to BWH from FAA, NHLBI, NIA, NIOSH, NASA, and DOD…JPH was supported, in part, by DOE grant DE- EE0008207, NAS Award #HR 05-23 UNIT 905; NASA grant NNX15AC14G…”

 

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Other papers of interest:

 

1

Hessel V, Liang S, Tran NN, Escribà-Gelonch M, Zeckovic O, Knowling M, Rebrov E, This H, Westra S, Fisk I, Gilliham M, Burgess A.

Front Astron Space Sci. 2022 Mar 8;9:841211. Review.

Note: This article may be obtained online without charge.

 

2

Moussa MS, Goldsmith M, Komarova SV.

JDR Clin Trans Res. 2022 Mar 20;23800844221084985. Online ahead of print.

Note: This article may be obtained online without charge.

 

3

Li W, Li R, Xie X, Chang Y.

Brain Behav. 2022 Mar 15;e32489. Online ahead of print.

Note: NASA Task Load Index assessment. From the abstract: “Pilots must process multiple streams of information simultaneously. Mental workload is one of the main issues in man–machine interactive mode when dealing with multiple tasks. This study aimed to combine functional near-infrared spectroscopy (fNIRS) and electrocardiogram (ECG) to detect changes in mental workload during multitasking in a simulated flight.” This article may be obtained online without charge.

 

4

Oluwafemi FA, Neduncheran A.

Adv Space Res. 2022 Apr 1;69(7):2921-9.

 

5

De B, Fu S, Chen YS, Das P, Ku K, Maroongroge S, Woodhouse KD, Hoffman KE, Nguyen QN, Reed VK, Chen AB, Koong AC, Smith BD, Smith GL.

Cancer Med. 2022 Mar 16. Online ahead of print.

Note: This article may be obtained online without charge.

 

6

Guo Z, Buonanno M, Harken A, Zhou G, Hei TK.

Radiat Res. 2022 Mar 15. Online ahead of print.

 

7

Yan Y, Fu J, Kowalchuk RO, Wright CM, Zhang R, Li X, Xu Y.

Transl Lung Cancer Res. 2022 Feb;11(2):307-22. Review.

Note: This article may be obtained online without charge.

 

8

Shamraeva MA, Pekov SI, Bormotov DS, Levin RE, Larina IM, Nikolaev EN, Popov IA.

Acta Astronaut. 2022 Mar 24. Online ahead of print.

 

9

Zeng X, Xie L, Ge Y, Zhou Y, Wang H, Chen Y, Zhu X, Liu H, Liao Q, Kong Y, Pan L, Li J, Xue L, Li S, Zhou X, Shi C, Sheng X.

Radiat Res. 2022 Mar 16. Online ahead of print.

 

10

Jung SM, Kim WU.

Immune Netw. 2022 Feb 17;22(1):e9. Review.

Note: This article may be obtained online without charge.

 

11

Custaud M-A, Vinogradova O, Gharib C, Delp M, Guerrero F, Murphy RP.

Front Physiol. 2022 Mar 17;13:870917.

Note: This article is part of the Research Topic “Cardio-vascular Dysfunction and Physiological Manifestations Induced by Environmental Conditions, Volume II” (https://www.frontiersin.org/research-topics/17903/cardio-vascular-dysfunction-and-physiological-manifestations-induced-by-environmental-conditions-vol#articles). The Research Topic also includes articles from previous Current Awareness Lists #959 https://doi.org/10.3389/fphys.2021.699493; #976 https://doi.org/10.3389/fphys.2021.760875, https://doi.org/10.3389/fphys.2021.656527, https://doi.org/10.3389/fphys.2021.712422; and #982 https://doi.org/10.3389/fphys.2021.753291. This article may be obtained online without charge.

 

12

Larsen LH, Lauritzen MH, Sinkjaer M, Kjaer TW.

JMIR Cardio. 2022 Mar 15;6(1):e31501.

Note: This article may be obtained online without charge.

 

13

Mason IC, Grimaldi D, Reid KJ, Warlick CD, Malkani RG, Abbott SM, Zee PC.

Proc Natl Acad Sci USA. 2022 Mar 22;119(12):e2113290119.

Note: This article may be obtained online without charge.

 

14

Tsimikas S.

Lipoprotein(a) and coronary calcium: Clinical management and potential design of primary prevention trials.

J Am Coll Cardiol. 2022 Mar 1;79(8):769-71.

Note: This article is an editorial comment to an article (Mehta et al.) in the “NASA” section above.

 

15

Sugimoto T, Imai S, Yoshikawa M, Fujisato T, Hashimoto T, Nakamura T.

J Appl Physiol (1985). 2022 Mar 17. Online ahead of print.

 

16

Leblanc Latour M, Pelling AE.

J Biomech. 2022 Apr;135:111030.

 

17

Mushtaq S.

Adv Exp Med Biol. 2022 Mar 15;1367:397-409.

 

18

Cheng Q, Lu C, Qian R.

Chronobiol Int. 2022 Mar 14;1-11. Online ahead of print.

 

19

Smith TJ, Wilson M, Whitney C, Fagnant H, Neumeier WH, Smith C, Heaton KJ, Cho E, Spielmann G, Walsh NP, Karl JP.

J Nutr. 2022 Mar 14;nxac064. Online ahead of print.

Note: This article may be obtained online without charge.

 

20

Green ES, Williams ER, Feito Y, Jenkins NT.

Res Q Exerc Sport. 2022 Mar 18;1-12. Online ahead of print.

Note: From the abstract: “We compared aerobic capacity (VO_2max), mitochondrial capacity (mVO₂), anaerobic power, strength, and muscle endurance in healthy, active men from strength (STR), endurance (END) and high-intensity functional training (HIFT) backgrounds.”