NASA Spaceline Current Awareness List #990 11 March 2022 (Space Life Science Research Results)

 

 

Papers deriving from NASA support:

 

1

Buckey JC Jr, Lan M, Phillips SD, Archambault-Leger V, Fellows AM.

J Appl Physiol (1985). 2022 Feb 24. Online ahead of print.

PI: J.C. Buckey Jr

Note: From the article: “Eliminating tissue compressive forces is not possible on Earth but can be simulated using numerical modeling. We developed a multicompartment, lumped-parameter, numerical model of the cranial circulation to develop hypotheses for SANS [spaceflight associated neuro-ocular syndrome]. The model has a circulatory sub-model, a CSF sub-model, and an aqueous humor sub-model implemented using MATLAB® Simscape Fluids™ (MathWorks®, Natick, MA). It incorporates tissue-weight generated compressive forces exerted on vessels, venous and arterial hydrostatic gradients, and the removal of those elements in microgravity.” This article may be obtained online without charge.

Journal Impact Factor: 3.495

Funding: “CA03401/National Space Biomedical Research Institute (NSBRI); NNX13AD35A/NASA/NASA/United States.”

 

2

Poignant F, Plante I, Crespo L, Slaba T.

Life. 2022 Mar 1;12(3):358.

Note: This is article is part of Special Issue “Space Radiobiology” (https://www.mdpi.com/journal/life/special_issues/space_radiobiology). The Special Issue also includes articles from previous Current Awareness Lists #968 https://doi.org/10.3390/life11080849, #977 https://doi.org/10.3390/life11111112 and https://doi.org/10.3390/life11111190, and #989 https://doi.org/10.3390/life12020144. Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.

Journal Impact Factor: 3.817

Funding: “This work is supported by NASA Human Health and Performance (HHPC) contract number NNJ15HK11B (IP); by the NASA Langley Cooperative Agreement 80LARC17C0004 (FP) and by the Human Research Program under the Human Exploration and Operations Mission Directorate at NASA (LC and TS).”

 

3

Harris HM, Boyet KL, Liu H, Dwivedi R, Ashpole NM, Tandon R, Bidwell GL 3^rd, Cheng Z, Fassero LA, Yu CS, Pomin VH, Mitra D, Harrison KA, Dahl E, Gurley BJ, Kotha AK, Chougule MB, Sharp JS.

Pharm Res. 2022 Mar 2;1-11.

PI: R. Tandon

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.200

Funding: “This work was supported in part by the University of Mississippi and the NIH funded Neuropharmacology Core Facility (P30 GM122733). Rodent in vivo imaging was performed in the Animal Imaging Core Facility at the University of Mississippi Medical Center. RT is supported by University of Mississippi Medical Center COVID-19 funds and NASA award (80NSSC19K1603).”

 

4

McNulty MJ, Hamada N, Delzio J, McKee L, Nandi S, Longo ML, McDonald KA.

J Nanobiotechnology. 2022 Mar 4;20(1):105.

PI: K.A. McDonald

Note: This article may be obtained online without charge.

Journal Impact Factor: 10.435

Funding: “This material is based upon work supported by NASA under grant or cooperative agreement award number NNX17AJ31G, a NASA Space Technology Research Fellowship (NASA grant number 80NSSC18K1157), the Translational Research Institute through NASA Cooperative Agreement NNX16AO69A, and the National Science Foundation (Grant number DMR–1806366).”

 

5

Antler CA, Yamazaki EM, Casale CE, Brieva TE, Goel N.

Front Neurosci. 2022 Feb 15;16:815697.

PI: N. Goel

Note: This article is part of Research Topic “Sleep and Circadian Rhythms in Cognitive and Physical Performance: What Do We Know and What Can We Do?” (https://www.frontiersin.org/research-topics/19741/sleep-and-circadian-rhythms-in-cognitive-and-physical-performance-what-do-we-know-and-what-can-we-do#articles). This article may be obtained online without charge.

Journal Impact Factor: 3.566

Funding: “This work was primarily supported by the Department of the Navy, Office of Naval Research (Award No. N00014-11-1- 0361) to NG Other support provided by National Aeronautics and Space Administration (NASA) NNX14AN49G and grant 80NSSC20K0243 (to NG), National Institutes of Health grant NIH R01DK117488 (to NG) and Clinical and Translational Research Center grant UL1TR000003.”

 

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Other papers of interest:

 

1

Rusanov V, Pastushkova L, Luchitskaya E, Goncharova A, Nosovsky A, Kussmaul A, Kashirina D, Nikolaev E, Orlov O, Larina I.

Acta Astronaut. 2022 Mar 3. Online ahead of print.

Note: ISS results.

 

2

Blaber AP, Goswami N, Xu D.

Acta Astronaut. 2022 Mar 5. Online ahead of print.

Note: Shuttle and head-down tilt bedrest results.

 

3

Riva P, Rusconi P, Pancani L, Chterev K.

Acta Astronaut. 2022 Mar 6. Online ahead of print.

Note: From the abstract: “This study focuses on the relationship between time spent in specific activities (e.g., talking about personal matters) and the social-psychological effects of social isolation and confinement as a part of the LUNARK project, which was aimed at building and testing the first Moon analog habitat.”

 

4

Ali YF, Hong Z, Liu NA, Zhou G.

Cancer Biol Ther. 2022 Mar 9;23(1):201-10. Review.

Note: This article may be obtained online without charge.

 

5

Rose BI.

Eur J Obstet Gynecol Reprod Biol. 2022 Apr 1;271:210-3.

 

6

Volkova T, Nicollier C, Gass V.

Front Physiol. 2022 Feb 16;13:832214.

Note: NASA Task Load Index assessment. From the article: “A total of 32 volunteers participated in the study (18 males, 14 females). All participants were right-hand dominant and reported that they did not currently have health issues. Two sets of experiments were conducted in a 1G and then underwater. Underwater conditions were used because Archimedes force counteracts the action of gravity.” This article is part of Research Topic “Investigation of the Inter-individual Variability of Physiological Responses to Changes in Activity Levels-, Gravity Loading-, Nutritional Status, Pharmaceuticals and Exposure to Radiation” (https://www.frontiersin.org/research-topics/14100/investigation-of-the-inter-individual-variability-of-physiological-responses-to-changes-in-activity#articles). The Research Topic also includes articles from previous Current Awareness Lists #921 https://doi.org/10.3389/fphys.2020.573581, #937 https://doi.org/10.3389/fphys.2021.614619, #952 https://doi.org/10.3389/fphys.2021.685473, #959 https://doi.org/10.3389/fphys.2021.676501, #979 https://doi.org/10.3389/fphys.2021.777611, #986 https://doi.org/10.3389/fphys.2022.810055, #987 https://doi.org/10.3389/fphys.2022.832214, and #988 https://doi.org/10.3389/fphys.2021.743876. This article may be obtained online without charge.

 

7

Dietrichs D, Grimm D, Sahana J, Melnik D, Corydon TJ, Wehland M, Krüger M, Vermeesen R, Baselet B, Baatout S, Hybel TE, Kahlert S, Schulz H, Infanger M, Kopp S.

Front Cell Dev Biol. 2022 Feb 17;10:841017.

Note: A random positioning machine was used in this study. This article is part of Research Topic “The Regulating Mechanisms of Development, Growth, and Metabolism: From Ground to Space” (https://www.frontiersin.org/research-topics/22183/the-regulating-mechanisms-of-development-growth-and-metabolism-from-ground-to-space#articles). The Research Topic also includes articles from previous Current Awareness Lists #975 https://doi.org/10.3389/fcell.2021.739944, #981 https://doi.org/10.3389/fcell.2021.797167, #985 https://doi.org/10.3389/fcell.2021.797060, and #989 https://doi.org/10.3389/fcell.2021.796902. This article may be obtained online without charge.

 

8

Fois M, Maule SV, Giudici M, Valente M, Ridolfi L, Scarsoglio S.

Front Physiol. 2022 Feb 17;13:826989.

Note: Head-up tilt results. This article may be obtained online without charge.

 

9

Wong V, Bell ZW, Sptiz RW, Song JS, Yamada Y, Abe T, Loenneke JP.

Physiol Int. 2022 Mar 3. Online ahead of print.

Note: Head-up tilt results.

 

10

Hao Z, Zhu Y, Fu Y, Yang J, Meng C, Dong C, Liu H.

Microbiol Spectr. 2022 Mar 7;e0025422. Online ahead of print.

Note: Beijing, China’s Lunar Palace 1, ground-based bioregenerative life support system results. This article may be obtained online without charge.

 

11

Int J Mol Sci. 2022 Mar 5;23(5):2847. Review.

Note: From the abstract: “This paper is a review of recent findings in the field of immunotherapy with an emphasis on immune checkpoint inhibitors.” This article is part of Special Issue “Immune Checkpoint Inhibitors and Immune Checkpoint Resistance” (https://www.mdpi.com/journal/ijms/special_issues/immune_checkpoint_inhibitors_resistance). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

12

Ahmad Rahman F, Quadrilatero J.

Semin Cell Dev Biol. 2022 Feb 28;S1084-9521(22)00039-8. Review. Online ahead of print.

 

13

Roelker SA, Schmitt LC, Chaudhari AMW, Siston RA.

PLoS One. 2022 Mar 3;17(3):e0264080.

Note: This article may be obtained online without charge.

 

14

Richardson ML, Amini B, Kinahan PE.

Radiol Clin North Am. 2022 Mar 1;60(2):339-58. Review.

 

15

Bouchet A, Le Clec’h C, Rogalev L, Le Duc G, Pelletier L.

Radiat Res. 2022 Mar 4. Online ahead of print.

 

16

Pannkuk EL, Laiakis EC, Angdisen J, Jayatilake MM, Ake P, Lin LY, Li HH, Fornace AJ.

Radiat Res. 2022 Mar 4. Online ahead of print.

 

17

Pedersen LN, Schiffer W, Mitchell JD, Bergom C.

Kardiol Pol. 2022 Mar 3. Online ahead of print.

Note: This article may be obtained online without charge.

 

18

Bonnefoy J, Baselet B, Moser D, Ghislin S, Miranda S, Riant E, Vermeesen R, Keiler AM, Baatout S, Choukér A, Frippiat JP.

Front Immunol. 2022 Feb 16;13:830662.

Note: Head-down tilt bed rest study. This article is part of Research Topic “Deciphering Immune and Neuroendocrine Crosstalk in Extreme Environments” (https://www.frontiersin.org/research-topics/22110/deciphering-immune-and-neuroendocrine-crosstalk-in-extreme-environments#articles). The Research Topic also includes an article from previous Current Awareness List #965 https://doi.org/10.3389/fimmu.2021.725748. Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

19

von Gall C.

Int J Mol Sci. 2022 Mar 3;23(5):2778.

Note: This article is part of Special Issue “Molecular and Cellular Mechanisms of Synchronization within the Mammalian Circadian System” (https://www.mdpi.com/journal/ijms/special_issues/Synchronization_Circadian). The Special Issue also includes two articles from previous Current Awareness List #967 https://doi.org/10.3390/ijms22179632 and https://doi.org/10.3390/ijms22052288. Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.

 

20

Xin Q, Yuan RK, Zitting KM, Wang W, Purcell SM, Vujovic N, Ronda JM, Quan SF, Williams JS, Buxton OM, Duffy JF, Czeisler CA.

Sleep. 2022 Feb 26;zsac046. Online ahead of print.

 

21

Hawliczek A, Brix B, Al Mutawa S, Alsuwaidi H, Du Plessis S, Gao Y, Qaisar R, Siddiqui R, Elmoselhi AB, Goswami N.

Acta Astronaut. 2022 Mar 7. Review. Online ahead of print.

Note: From the abstract: “This review presents an update of available literature on the hind-limb unloading model.”

 

22

Kovalev VS, Grandl W, Manukovsky NS, Tikhomirov AA, Bӧck C.

Life Sci Space Res. 2022 May;33:1-6.

Note: From the abstract: “To calculate the equivalent system mass of mushrooms, a conceptual configuration of a mushroom farm as part of a bioregenerative life support system on an inhabited lunar base was designed.”