NASA Spaceline Current Awareness List #987. 18 February 2022 (Space Life Science Research Results)

 

Papers deriving from NASA support:

 

1

Johnson CM, Boles HO, Spencer LE, Poulet L, Romeyn M, Bunchek JM, Fritsche R, Massa GD, O’Rourke A, Wheeler RM.

Front Astron Space Sci. 2021 Nov 10;8:734343. Mini review.

PI: C.M. Johnson, NASA Postdoctoral Program Fellowship

Note: This article, the article directly below (Poulet et al.), and an article below in the “Other” section (Duri et al.) are part of Research Topic “Bioregenerative Life-Support Systems for Crewed Missions to the Moon and Mars” (https://www.frontiersin.org/research-topics/16705/bioregenerative-life-support-systems-for-crewed-missions-to-the-moon-and-mars#articles). The Research Topic also includes articles from previous Current Awareness Lists #960 https://doi.org/10.3389/fspas.2021.699688, https://pubmed.ncbi.nlm.nih.gov/34276632,https://doi.org/10.3389/fspas.2021.700370, https://doi.org/10.3389/fspas.2021.711550, https://doi.org/10.3389/fmicb.2021.700010, https://doi.org/10.3389/fspas.2021.700579,https://doi.org/10.3389/fspas.2021.699097; #961 https://doi.org/10.3389/fspas.2021.665649; #962 https://doi.org/10.3389/fspas.2021.700270; #964 https://doi.org/10.3389/fmicb.2021.709746; #975 https://doi.org/10.3389/fmicb.2021.700810; and #979 https://doi.org/10.3389/fmicb.2021.733244. This article may be obtained online without charge.

Journal Impact Factor: 5.2

Funding: “Funding for this review manuscript provided through NASA Biological and Physical Sciences Program, and NASA’s Advanced Exploration Systems Program.”

 

2

Poulet L, Engeling K, Hatch T, Stahl-Rommel S, Velez Justiniano Y-A, Castro-Wallace S, Bunchek J, Monje O, Hummerick M, Khodadad CLM, Spencer LE, Pechous J, Johnson CM, Fritsche R, Massa GD, Romeyn MW, O’Rourke AE, Wheeler RW.

Front Astron Space Sci. 2022 Feb 4;8:733944.

PI: L. Poulet, NASA Postdoctoral Program Fellowship

Note: This article, the article directly above (Johnson et al.), and an article below in the “Other” section (Duri et al.) are part of Research Topic “Bioregenerative Life-Support Systems for Crewed Missions to the Moon and Mars” (https://www.frontiersin.org/research-topics/16705/bioregenerative-life-support-systems-for-crewed-missions-to-the-moon-and-mars#articles). This article may be obtained online without charge.

Journal Impact Factor: 5.2

Funding: “Funding provided in part by NASA Biological and Physical Sciences Program.”

 

3

McGill MR, Findley DL, Mazur A, Yee EU, Allard FD, Powers A, Coward L, Blough ER, Gorman G, Hambuchen MD.

Eur J Drug Metab Pharmacokinet. 2022 Feb 8. Online ahead of print.

Journal Impact Factor: 2.448

Funding: “This work was supported by the NASA WV EPSCoR Research Seed Grant.”

 

4

Burket JA, Matar M, Fesshaye A, Pickle JC, Britten RA.

Radiat Res. 2021 Oct 1;196(4):345-54.

PI: R.A. Britten

Journal Impact Factor: 2.841

Funding: “This work was funded by NASA (grant no. NNX14AE73G to RAB) and the NASA Human Research Program (MM). We are indebted to Dr. Adam Rusek and his staff for their assistance with animal irradiations at Brookhaven National Laboratories. This study would not have been possible without their help.”

 

5

Lim S, Bijlani S, Blachowicz A, Chiang YM, Lee MS, Torok T, Venkateswaran K, Wang CCC.

Fungal Genet Biol. 2021 Jul;152:103567.

PI: C.C.C. Wang

Journal Impact Factor: 3.495

Funding: “…This research was funded by NASA’s 2018 Space Biology (ROSBio) NNH18ZTT001N-FG App B: Flight and Ground Space Biology Research Grant 80NSSC19K1501 awarded to C.C.C.W. Part of the research described in this publication was conducted at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with NASA. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise does not constitute or imply its endorsement by the U.S. Government or the Jet Propulsion Laboratory, California Institute of Technology. This research was supported by the JPL Advanced Concept Development fund awarded to K.V. that funded a portion of the fellowships for AB.”

 

6

Lee W, Weisholtz DS, Strangman GE, Yoo S.

Brain Neurorehabil. 2021 Mar;14(1):e4.

PI: S.S. Yoo

Journal Impact Factor: Not available for this journal

Funding: “This study was supported by NASA TRISH through Baylor College of Medicine (NNX16A069A, to SS Yoo). …”

 

7

Van Fossen JA, Olenick J, Ayton J, Chang C-H, Kozlowski SWJ.

Acta Astronaut. 2021 Dec 1;189:658-70.

PI: S.W.J. Kozlowski

Journal Impact Factor: 2.413

Funding: “…We gratefully acknowledge the National Aeronautics and Space Administration (NASA; NNX13AM77G and NNX16AR52G, S.W.J. Kozlowski, Principal Investigator; C.-H. Chang, Co-Investigator) for support that contributed to this research. …“

 

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Other papers of interest:

 

1

Kuga T, Sunagawa N, Igarashi K.

Cellulose (Lond). 2022 Jan 29:1-17. Online ahead of print.

Note: ISS results. This article may be obtained online without charge.

 

2

Sudevan S, Muto K, Higashitani N, Hashizume T, Higashibata A, Ellwood RA, Deane CS, Rahman M, Vanapalli SA, Etheridge T, Szewczyk NJ, Higashitani A.

iScience. 2022 Feb 18;25(2):103762.

Note: ISS results. A 3D clinostat was used in this study. This article may be obtained online without charge.

 

3

Bateman GA, Bateman AR.

npj Microgravity. 2022 Feb 15;8(1):3. Review.

Note: From the abstract: “The purpose of the present paper is to review the SANS [neuro-ocular syndrome] vascular dynamics literature and through mathematical modelling suggest the possible underlying cause of SANS as an elevation in venous sinus pressure, secondary to the redistribution of fluids towards the head, together with a significant increase in pressure drop across the venous system related to the CBF [cerebral blood flow].” This article may be obtained online without charge.

 

4

Jirak P, Mirna M, Rezar R, Motloch LJ, Lichtenauer M, Jordan J, Binneboessel S, Tank J, Limper U, Jung C.

Eur J Prev Cardiol. 2022 Feb 11;zwac029. Review. Online ahead of print.

Note: Head-down bed rest study. From the abstract: “This review provides an overview on studies conducted in space and in terrestrial models, particularly head-down bedrest studies.”

 

5

Cucinotta FA, Saganti PB.

Sci Rep. 2022 Feb 7;12(1):2028.

Note: NASA Space Cancer Risk model was used in this study. From the article: “We use these recent LSS [Life Span Study] findings and the NASA Space Cancer Risk model (NSCR-2020)23–27) to make predictions of cancer risks from GCR for U.S. populations as a function of sex and age for Asian-Pacifc Islanders (API), Black, Hispanic (Black and White), and White (non-Hispanic) populations.” This article may be obtained online without charge.

 

6

Duri LG, Caporale AG, Rouphael Y, Vingiani S, Palladino M, De Pascale S, Adamo P.

Front Astron Space Sci. 2022 Jan 4;8:747821. Review.

Note: This article and two articles above in the “NASA” section (Johnson et al. and Poulet et al.) are part of Research Topic “Bioregenerative Life-Support Systems for Crewed Missions to the Moon and Mars” (https://www.frontiersin.org/research-topics/16705/bioregenerative-life-support-systems-for-crewed-missions-to-the-moon-and-mars#articles). This article may be obtained online without charge.

 

7

Lebedeva S, Shved D, Savinkina A.

Front Physiol. 2022 Feb 11;12:751016.

Note: Dry immersion results. This article is part of Research Topic “Brains in Space: Effects of Spaceflight on the Human Brain and Behavior” (https://www.frontiersin.org/research-topics/19134/brains-in-space-effects-of-spaceflight-on-the-human-brain-and-behavior#articles). The Research Topic also includes articles from previous Current Awareness Lists #956 https://doi.org/10.3389/fncir.2021.659557; #967 https://doi.org/10.3389/fphys.2021.654906; #969 https://doi.org/10.3389/fphys.2021.746509; #973 https://doi.org/10.3389/fncir.2021.723504; #975 https://doi.org/10.3389/fncir.2021.757817, https://doi.org/10.3389/fncir.2021.760313, and https://doi.org/10.3389/fphys.2021.750414; #976 https://doi.org/10.3389/fphys.2021.770502; #977 https://doi.org/10.3389/fphys.2021.782860; #979 https://doi.org/10.3389/fncir.2021.750176; #982 https://doi.org/10.3389/fphys.2021.795321; and #985 https://doi.org/10.3389/fphys.2022.806357. This article may be obtained online without charge.

 

8

Kuehnast T, Abbott C, Pausan MR, Pearce DA, Moissl-Eichinger C, Mahnert A.

Microbiome. 2022 Feb 7;10(1):26. Commentary.

Note: From the abstract: “In this commentary, we focus on the current state of knowledge regarding a healthy (gut) microbiome of space travelers based on research from the International Space Station and simulation experiments on Earth.” This article may be obtained online without charge.

 

9

Lomax BA, Just GH, McHugh PJ, Broadley PK, Hutchings GC, Burke PA, Roy MJ, Smith KL, Symes MD.

Nat Commun. 2022 Feb 8;13(1):583.

Note: A short-arm centrifuge was used in this study. This article may be obtained online without charge.

 

10

Du J, He Z, Xu M, Qu X, Cui J, Zhang S, Zhang S, Li H, Yu Z.

Front Endocrinol. 2022 Jan 20;12:778019.

Note: This article is part of the Research Topic “Fat and Skeletal Metastasis” (https://www.frontiersin.org/research-topics/24284/fat-and-skeletal-metastasis#articles). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

11

Fu R, Bertrand D, Wang J, Kavaseri K, Feng Y, Du T, Liu Y, Willie BM, Yang H.

Comput Methods Programs Biomed. 2022 Apr;216:106679. Online ahead of print.

 

12

Saito M, Hirano M, Izumi T, Mori Y, Ito K, Saitoh Y, Terada N, Sato T, Sukegawa J.

Int J Mol Sci. 2022 Feb 14;23(4):2094.

Note: This article is part of the Special Issue “Bone Development and Regeneration 2.0” (https://www.mdpi.com/journal/ijms/special_issues/bone_regeneration2). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.

 

13

Sun Y, Wan B, Wang R, Zhang B, Luo P, Wang D, Nie JJ, Chen D, Wu X.

Front Cell Dev Biol. 2022 Jan 21;10:808303. Review.

Note: This article is part of the Research Topic “Development, Metabolism, Senescence and Mechanotransduction of Bone” (https://www.frontiersin.org/research-topics/24709/development-metabolism-senescence-and-mechanotransduction-of-bone#articles). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

14

Du J, Kageyama SI, Yamashita R, Hirata H, Hakozaki Y, Okumura M, Motegi A, Hojo H, Nakamura M, Hirano Y, Sunakawa H, Minamide T, Kotani D, Tanaka K, Yano T, Kojima T, Ohashi A, Tsuchihara K, Akimoto T.

Cancer Sci. 2022 Feb 8. Online ahead of print.

Note: This article may be obtained online without charge.

 

15

Lalkovicova M.

Neural Regen Res. 2022 Feb 8;17(9):1885-92. Review.

Note: This article may be obtained online without charge.

 

16

Son B, Kim TR, Park JH, Yun SI, Choi H, Choi JW, Jeon C, Park HO.

Radiat Res. 2022 Feb 11. Online ahead of print.

 

17

Yi P, Li H, Su J, Cai J, Xu C, Chen J, Cao L, Li M.

Am J Cancer Res. 2022 Jan 15;12(1):381-95.

Note: This article may be obtained online without charge.

 

18

Volkova T, Nicollier C, Gass V.

Front Physiol. 2022 Feb 16;13:832214.

Note: An underwater tank was used in this study. NASA Task Load Index assessment. This article is part of Research Topic “Investigation of the Inter-individual Variability of Physiological Responses to Changes in Activity Levels-, Gravity Loading-, Nutritional Status, Pharmaceuticals and Exposure to Radiation” (https://www.frontiersin.org/research-topics/14100/investigation-of-the-inter-individual-variability-of-physiological-responses-to-changes-in-activity#articles). The Research Topic also includes articles from previous Current Awareness Lists #921 https://doi.org/10.3389/fphys.2020.573581, #937 https://doi.org/10.3389/fphys.2021.614619, #952 https://doi.org/10.3389/fphys.2021.685473, #959 https://doi.org/10.3389/fphys.2021.676501, #979 https://doi.org/10.3389/fphys.2021.777611, and #986 https://doi.org/10.3389/fphys.2022.810055. This article may be obtained online without charge.

 

19

Jiang N, Li YJ, Wang MD, Huang H, Chen S, Li Y, Qu L, Wang F, Liu X, Wang Q.

Front Psychiatry. 2022 Jan 19;12:596017.

Note: This article is part of Research Topic “Natural Products as Sources of Innovative Approaches in Psychiatry” (https://www.frontiersin.org/research-topics/14098/natural-products-as-sources-of-innovative-approaches-in-psychiatry#articles). This article may be obtained online without charge.

 

20

Lee KY, Park SJ, Matthews DG, Kim SL, Marquez CA, Zimmerman JF, Ardoña HAM, Kleber AG, Lauder GV, Parker KK.

Science. 2022 Feb 11;375(6581):639-47.

Note: From the abstract: “Biohybrid systems have been developed to better understand the design principles and coordination mechanisms of biological systems. We consider whether two functional regulatory features of the heart-mechanoelectrical signaling and automaticity-could be transferred to a synthetic analog of another fluid transport system: a swimming fish. By leveraging cardiac mechanoelectrical signaling, we recreated reciprocal contraction and relaxation in a muscular bilayer construct where each contraction occurs automatically as a response to the stretching of an antagonistic muscle pair.”

 

21

Ugur E, Konukseven BO.

Auris Nasus Larynx. 2022 Feb 3;S0385-8146(22)00030-X. Online ahead of print.

 

22

Zhong W, Zhu J, Yi J, Zhao C, Shi Y, Kang Q, Huang J, Hao L, Lu J.

J Ethnopharmacol. 2022 May:115077. Online ahead of print.

 

23

Zhu Y, Deng H, She H, Zhou Y, Wu Y, Zhang J, Liu L, Tao L.

Front Physiol. 2022 Feb 4;13:827838.

Note: From the abstract: “Previous studies found that seawater immersion combined with hemorrhagic shock (SIHS) induced serious organ function disorder, and lethal triad was a critical sign. There were no effective treatments of SIHS. Fluid resuscitation was the initial measurement for early aid following hemorrhagic shock, while the proper fluid for SIHS is not clear. Effects of different osmotic pressures [lactated Ringer’s (LR) solution, 0.3% saline, 0.6% saline, and 0.9% normal saline] on the lethal triad, mitochondrial function, vital organ functions, and survival were observed following SIHS in rats.” This article may be obtained online without charge.

 

24

Du J, Lin X, Cai Y, Sun F, Amankwah-Amoah J.

Front Psychol. 2022 Jan 21;12:646514.

Note: This article is part of Research Topic “New Perspectives in the Study of Group Dynamics” (https://www.frontiersin.org/research-topics/13394/new-perspectives-in-the-study-of-group-dynamics#articles). This article may be obtained online without charge.