NASA Spaceline Current Awareness List #981 7 January 2022 (Space Life Science Research Results)

 

Papers deriving from NASA support:

 

1

McGregor HR, Hupfeld KE, Pasternak O, Wood SJ, Mulavara AP, Bloomberg JJ, Hague TN, Seidler RD.

Front Neurol. 2021 Dec 9;12:774805. Case report.

PI: R.D. Seidler

Note: ISS and Russian Soyuz MS-10 mission results. From the abstract: “Here, we describe a case report of a Crewmember who experienced an Aborted Launch (‘CAL’). CAL’s launch and landing experience was dissociated from prolonged microgravity exposure. Using MRI, we show that hypergravity exposure during the aborted launch did not induce lasting ventricular enlargement or intracranial fluid shifts resembling those previously reported with spaceflight. This case study therefore rules out hypergravity during launch and landing as a contributing factor to previously reported long-lasting intracranial fluid changes following spaceflight.” This article may be obtained online without charge.

Journal Impact Factor: 4.003

Funding: “This study was supported by NASA grant #NNX11AR02G awarded to RS, AM, SW, and JB. HM was supported by a NSERC postdoctoral fellowship and a NASA Human Research Program augmentation grant. KH was supported by a National Institute on Aging fellowship 1F99AG068440.”

 

2

Nicholson WL, Fajardo-Cavazos P, Turner C, Currie TM, Gregory G, Jurca T, Weislogel M.

Front Space Technol. 2021 Dec 22;2:797518.

PIs: W.L. Nicholson, M. Weislogel

Note: ISS results. This article is part of Research Topic “Technologies for Handling, Preparation, and Liquid-Based Analysis of Fluidic Samples in Space.” (https://www.frontiersin.org/research-topics/18491/technologies-for-handling-preparation-and-liquid-based-analysis-of-fluidic-samples-in-space#articles). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “WN and PF-C were funded by the University of Florida Space Research Initiative (OR-DRPD-SRI2019) and NASA (NNX14AT38G and 80NSSC21K0319). CT and MW were supported in part through NASA Applied Capillary Fluidics Cooperative Agreement 80NSSC18K0436. TJ thanks the University of Central Florida Department of Chemistry, College of Science, and Faculty Cluster Initiative for startup funding.”

 

3

Singh NK, Lavire C, Nesme J, Vial L, Nesme X, Mason CE, Lassalle F, Venkateswaran K.

Front Microbiol. 2021 Dec 6;12:765943.

PI: K. Venkateswaran

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 5.640

Funding: “Part of the research described in this publication was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with National Aeronautics and Space Administration. This research was funded by a 2012 Space Biology NNH12ZTT001N grant no. 19-12829-26 under Task Order NNN13D111T award to KV, which also funded the post-doctoral fellowships for NS. This research was funded in part to FL by the Wellcome Trust Grant (206194).”

 

4

Meier A, Essumang D, Hummerick M, Johnson C, Kruger M, Massa G, Engeling K.

Gravit Space Res. 2021 Dec 23;9(1):133-58. Review.

Note: From the abstract: “This review paper brings together the current state-of-the-art reported literature to aide in understanding plasma seed application apparatus, seed or crop performance pertaining to germination, growth, water interactions, inactivation of bacteria, and surface sanitization results.” This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “Funding for this work was provided by the NASA KSC Independent Research and Technology Development (IR&TD) Program. The authors would like to thank inputs from the project team at Kennedy Space Center (KSC), including Dr. Ray Wheeler, intern Aniya Norvell, and Dr. Ryan Gott.”

 

5

Reid CR, Charvat JM, McFarland SM, Norcross JR, Benson E, England S, Rajulu S.

Hum Factors. 2021 Dec 27;187208211062299. Online ahead of print.

PI: J.R. Norcross

Note: From the article: “This paper was a secondary analysis from a larger retrospective EVA [extravehicular activity] glove injury data mining investigation conducted between 2012 and 2014, which focused on three decades of EVA training and spaceflight data. The goal of the larger study was to conduct a broad injury assessment of all injuries that occurred to the upper extremities between the fingernails and the elbow.”

Journal Impact Factor: 2.888

Funding: “The authors thank Millennia Young and Caroline Schaefer of NASA’s Lifetime Surveillance of Astronaut Health who assisted with the statistical analysis of the study. Additionally, we express sincere gratitude to Scott Cupples of the NASA JSC EVA Flight Office, who provided historical insight into the contextual changes and uses of EVA gloves over the three decades this study covered. Lastly, the authors thank Jane Krauhs for technical editing of the submission.”

 

6

Sharma A, Clemens RA, Garcia O, Taylor DL, Wagner NL, Shepard KA, Gupta A, Malany S, Grodzinsky AJ, Kearns-Jonker M, Mair DB, Kim DH, Roberts MS, Loring JF, Hu J, Warren LE, Eenmaa S, Bozada J, Paljug E, Roth M, Taylor DP, Rodrigue G, Cantini P, Smith AW, Giulianotti MA, Wagner WR.

Stem Cell Reports. 2021 Dec 16;S2213-6711(21)00598-1. Review. Online ahead of print.

PI: S. Gerecht

Note: From the abstract: “Research in low Earth orbit (LEO) has become more accessible. The 2020 Biomanufacturing in Space Symposium reviewed space-based regenerative medicine research and discussed leveraging LEO to advance biomanufacturing for regenerative medicine applications. The symposium identified areas where financial investments could stimulate advancements overcoming technical barriers. Opportunities in disease modeling, stem-cell-derived products, and biofabrication were highlighted. The symposium will initiate a roadmap to a sustainable market for regenerative medicine biomanufacturing in space. This perspective summarizes the 2020 Biomanufacturing in Space Symposium, highlights key biomanufacturing opportunities in LEO, and lays the framework for a roadmap to regenerative medicine biomanufacturing in space.” This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “The Biomanufacturing in Space Symposium and this report are funded by NSF /CMMI #2028635 (M.A.G.), an American Heart Association Career Development Award 856987 (A.S.), the Translational Research Institute through NASA #20-20TSRAD-2-0007 (D.-H.K.), and the NIH UH3TR003519 (D.-H.K.).”

 

7

Schroeder MK, Liu B, Hinshaw RG, Park MA, Wang S, Dubey S, Liu GG, Shi Q, Holton P, Reiser V, Jones PA, Trigg W, Di Carli MF, Caldarone BJ, Williams JP, O’Banion MK, Lemere CA.

Int J Mol Sci. 2021 Dec 10;22(24):13305.

PI: C.A. Lemere

Note: This article is part of Special Issue “Molecular Research in Radiobiology” (https://www.mdpi.com/journal/ijms/special_issues/Radiobiology). This article may be obtained online without charge.

Journal Impact Factor: 5.924

Funding: “This research was funded by grants from the National Aeronautic and Space Administration (NASA): NNX14AI07G and 80NSSC18K0810 (both to CAL).”

 

8

Romsdahl J, Schultzhaus Z, Cuomo CA, Dong H, Abeyratne-Perera H, Hervey WJt, Wang Z.

J Fungi (Basel). 2021 Dec 15;7(12):1078.

PI: Z. Wang

Note: This article is part of Special Issue “Yeast Biorefineries” (https://www.mdpi.com/journal/jof/special_issues/Yeast_Biorefineries). This article may be obtained online without charge.

Journal Impact Factor: 5.816

Funding: “This work was supported by the Defense Threat Reduction Agency Grant HDTRA-17-1-002 and NASA Grant NNK190B09A.”

 

9

Uemura T, Wang J, Aratani Y, Gilroy S, Toyota M.

JoVE. 2021 Jun 6;(172):e62114.

PI: S. Gilroy

Note: From the abstract: “Here, we introduce a plant-wide, real-time imaging method to monitor the dynamics of both the Ca²⁺ signals and changes in apoplastic glutamate that occur in response to wounding. This approach uses a wide-field fluorescence microscope and transgenic Arabidopsis plants expressing Green Fluorescent Protein (GFP)-based Ca²⁺ and glutamate biosensors.”

Journal Impact Factor: 1.4

Funding: “This work was supported by grants from the Japan Society for the Promotion of Science (17H05007 and 18H05491) to MT, the National Science Foundation (IOS1557899 and MCB2016177) and the National Aeronautics and Space Administration (NNX14AT25G and 80NSSC19K0126) to SG.”

 

10

Hammond TG, Nislow C, Christov IC, Batuman V, Nagrani PP, Barazandeh M, Upadhyay R, Giaever G, Allen PL, Armbruster M, Raymond A, Birdsall HH.

Sci Rep. 2021 Oct 29;11(1):21296.

PI: T.G. Hammond

Note: The Published Erratum titled, “Author Correction: Cell spinpods are a simple inexpensive suspension culture device to deliver fluid shear stress to renal proximal tubular cells,” can be found at https://pubmed.ncbi.nlm.nih.gov/34819606. This article may be obtained online without charge.

Journal Impact Factor: 4.380

Funding: “NASA Grant 80NSSC19K0706 under solicitation NNH18ZTT001N-EM1 to the Institute for Medical Research supported these studies.”

 

11

Coronado I, Abdelkhaleq R, Yan J, Marioni SS, Jagolino-Cole A, Channa R, Pachade S, Sheth SA, Giancardo L.

Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:3873-6.

PI: L. Giancardo

Journal Impact Factor: 1.04

Funding: “This work is supported by the Translational Research Institute through NASA Cooperative Agreement NNX16AO69A. This research has been conducted using the UK Biobank resource. Ivan Coronado is supported by a training fellowship from the Gulf Coast Consortia, on the NLM Training Program in Biomedical Informatics & Data Science (T15LM007093).”

 

_______________________________________________________

 

 

Other papers of interest:

 

1

Krivonosov YS, Gulimova VI, Buzmakov AV, Zolotov DA, Cedola A, Bukreeva I, Asadchikov VE, Saveliev SV.

Front Physiol. 2021 Dec 7;12:752893.

Note: Russian spacecraft Foton-M3 mission results. This article may be obtained online without charge.

 

2

Pantalone D, Faini GS, Cialdai F, Sereni E, Bacci S, Bani D, Bernini M, Pratesi C, Stefàno P, Orzalesi L, Balsamo M, Zolesi V, Monici M.

Robot-assisted surgery in space: Pros and cons. A review from the surgeon‘s point of view.

npj Microgravity. 2021 Dec 21;7(1):56. Review.

Note: This article may be obtained online without charge.

 

3

Pavez Loriè E, Baatout S, Choukér A, Buchheim JI, Baselet B, Dello Russo C, Wotring V, Monici M, Morbidelli L, Gagliardi D, Stingl JC, Surdo L, Yip VLM.

Front Bioeng Biotechnol. 2021 Dec 13;9:739747. Review.

Note: This article is part of Research Topic “Space (Nano)Medicine” (https://www.frontiersin.org/research-topics/18488/space-nanomedicine#articles). The Research Topic also includes an article from previous Current Awareness List #950 https://doi.org/10.3389/fbioe.2021.666683. Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

4

Barravecchia I, De Cesari C, Forcato M, Scebba F, Pyankova OV, Bridger JM, Foster HA, Signore G, Borghini A, Andreassi M, Andreazzoli M, Bicciato S, Pè ME, Angeloni D.

Cell Mol Life Sci. 2021 Dec 22;79(1):28. Online ahead of print.

Note: The method of simulated microgravity and the spaceflight information are not evident in the available abstract. From the abstract: “Microgravity and space radiation (SR) are two highly influential factors affecting humans in space flight (SF). Many health problems reported by astronauts derive from endothelial dysfunction and impaired homeostasis. Here, we describe the adaptive response of human, capillary endothelial cells to SF.”

 

5

Li F, Ye Y, Lei X, Zhang W.

Front Cell Dev Biol. 2021 Dec 2;9:797167. Mini review.

Note: This article is part of Research Topic “The Regulating Mechanisms of Development, Growth, and Metabolism: From Ground to Space” (https://www.frontiersin.org/research-topics/22183/the-regulating-mechanisms-of-development-growth-and-metabolism-from-ground-to-space#articles). The Research Topic also includes an article from previous Current Awareness List #975 https://doi.org/10.3389/fcell.2021.739944. Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

6

Amini K, Janabadi ED, Fayaz R.

Acta Astronautica. 2022 Mar;192:210-32.

 

7

Baldry M, Gurieff N, Keogh D.

Acta Astronautica. 2022 Mar;192:190-8.

 

8

Delle Monache S, Indovina I, Zago M, Daprati E, Lacquaniti F, Bosco G.

Front Integr Neurosci. 2021 Dec 1;15:793634. Review.

Note: This article is part of Research Topic “Role of the Vestibular System in the Perception of Time and Space” (https://www.frontiersin.org/research-topics/20823/role-of-the-vestibular-system-in-the-perception-of-time-and-space#articles). The Research Topic also includes an article from previous Current Awareness List #970 https://doi.org/10.3389/fnint.2021.742100. Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

9

Ninokawa S, Nordham K.

Proc (Bayl Univ Med Cent). 2022;35(1):129-32. Available online 1 September 2021.

Note: This article may be obtained online without charge.

 

10

Tanaka M, Kanazashi M, Kondo H, Fujino H.

Time course of capillary regression and an expression balance between vascular endothelial growth factor-A and thrombospondin-1 in the soleus muscle of hindlimb unloaded rats.

Muscle Nerve. 2021 Dec 26. Online ahead of print.

Note: Hindlimb unloading study.

 

11

Abbas SR, Khan RT, Shafique S, Mumtaz S, Khan AA, Khan AM, Hassan Z, Hussain SA, Abbas S, Abbas MR, Batool A, Safder MA.

Braz J Biol. 2021 Dec 2;83:e248024.

Note: This article may be obtained online without charge.

 

12

Resendes C, Horan DJ, Robling AG, Gao B, Milne GL, Warman ML.

Bone. 2021 Dec 29:116307. Online ahead of print.

 

13

Luo N, Zhu W, Li X, Fu M, Peng X, Yang F, Zhang Y, Yin H, Yang C, Zhao J, Yuan X, Hu G.

Radiat Res. 2022 Jan 4. Online ahead of print.

 

14

Tanooka H.

J Radiat Res. 2021 Dec 20;rrab109. Online ahead of print.

Note: This article may be obtained online without charge.

 

15

Wei W, Bai H, Chen Y, Zhang T, Zhang Y, Hua J, He J, Ding N, Zhou H, Wang J.

Int J Mol Sci. 2021 Dec 15;22(24):13476.

Note: This article is part of Special Issue “miRNAs in the Era of Personalized Medicine: From Biomarkers to Therapeutics 2.0” (https://www.mdpi.com/journal/ijms/special_issues/miRNAs_2). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.

 

16

Corken A, Ghosh SP, Du R, Boerma M, Ware J, Pathak R.

Radiother Oncol. 2021 Dec 28;S0167-8140(21)09078-2. Online ahead of print.

 

17

Huang G.

Biophys J. 2021 Dec 14;S0006-3495(21)03907-2. Online ahead of print.

 

18

Smart LJ, Drew A, Hadidon T, Teaford M, Bachmann E.

Hum Factors. 2021 Dec 20;187208211059623. Online ahead of print.

 

19

Zhang X, Sun Y.

Int J Environ Res Public Health. 2021 Dec 14;18(24):13163.

Note: This article may be obtained online without charge.

 

20

Nordine M, Schwarz A, Bruckstein R, Gunga H-C, Opatz O.

Note: This article is part of Research Topic “Physiology and Physiopathology of Breath-Holding Activity” (https://www.frontiersin.org/research-topics/17771/physiology-and-physiopathology-of-breath-holding-activity#articles). The Research Topic also includes an article from previous Current Awareness List #978 https://doi.org/10.3389/fphys.2021.712573. This article may be obtained online without charge.

 

21

Nosikova I, Riabova A, Amirova L, Kitov V, Tomilovskaya E.

Front Hum Neurosci. 2021 Dec 1;15:753259.

Note: This article is part of Research Topic “Women in Neuroscience” (https://www.frontiersin.org/research-topics/19592/women-in-neuroscience#articles). The Research Topic also includes an article from previous Current Awareness List #975 https://doi.org/10.3389/fnhum.2021.756674. Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

22

Rivera PM, Proppe CE, Beltran E, Hill EC.

High Alt Med Biol. 2021 Dec 21. Online ahead of print.

 

23

Garnier YM, Lepers R, Canepa P, Martin A, Paizis C.

Note: This article may be obtained online without charge.