NASA Spaceline Current Awareness List #980 23 December 2021 (Space Life Science Research Results)

 

 

 

Papers deriving from NASA support:

 

1

Hagan ML, Balayan V, McGee-Lawrence ME.

Bone. 2021 Aug;149:115970. Review.

PI: M.E. McGee-Lawrence

Journal Impact Factor: 4.398

Funding: “The authors are supported by funding provided by the NASA Space Biology Program (80NSSC21K0274), the National Science Foundation (CMMI 1727949) and the National Institute on Aging (NIA P01 AG036675 and R01 AG067510).”

 

2

Britten RA, Fesshaye A, Ihle P, Wheeler A, Baulch JE, Limoli CL, Stark CE.

Radiat Res. 2021 Dec 17. Online ahead of print.

PIs: R.A. Britten, C. Limoli

Journal Impact Factor: 2.841

Funding: “This work was funded by NASA grant support NNX15AI22G and NNX14AE73G.”

 

3

Galli O, Jones CW, Larson O, Basner M, Dinges DF.

Sleep. 2021 Nov 22;zsab278. Online ahead of print.

PIs: M. Basner, D.F. Dinges

Journal Impact Factor: 5.849

Funding: “NR004281/NH/NIH HHS/United States; NASA NCC 9-58/National Space Biomedical Research Institute; 5T32HL007713/NIH National Research Service Award.”

 

4

Kruse CPS, Wyatt SE.

Plant Sci. 2022 Jan;314:111105. Review.

PI: S.E. Wyatt

Note: ISS results. From the abstract: “Herein, we provide a review of existing knowledge of gravity response and differential protein and gene regulation induced by the absence of gravity stimulus aboard the International Space Station and propose an integrated theoretical schematic of gravity response incorporating that information.”

Journal Impact Factor: 4.729

Funding: PI reports follow-up on BRIC 20 funding.

 

5

Khan S, Kirubarajan A, Lee M, Pitha I, Buckey JC Jr.

Aerosp Med Hum Perform. 2021 Nov 1;92(11):886-97. Review.

PI: J.C. Buckey Jr

Note: From the abstract: “Preflight body weight is a strong predictor of visual changes in spaceflight. To understand the effect of body weight on the eye, we examined the effect of increased body mass index on intraocular pressure on Earth.”

Journal Impact Factor: 0.889

Funding: PI reports SANS project funding.

 

6

Torres LJ, Weislogel MM.

npj Microgravity. 2021 Dec 17;7(1):52.

PI: M.M. Weislogel

Note: From the abstract: “When confined within containers or conduits, drops and bubbles migrate to regions of minimum energy by the combined effects of surface tension, surface wetting, system geometry, and initial conditions. Such capillary phenomena are exploited for passive phase separation operations in micro-fluidic devices on earth and macro-fluidic devices aboard spacecraft. Our study focuses on the migration and ejection of large inertial-capillary drops confined between tilted planar hydrophobic substrates (a.k.a., wedges).”

Journal Impact Factor: 4.415

Funding: “This work was funded in part through NASA cooperative agreements NNX12AO47A and NNX16AC38G, and NIAC grant NNX15AR93G (PI John Graf, NASA JSC). L.T.”

 

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Other papers of interest:

 

1

Luchitskaya ES, Funtova II, Tank J, Reuter H, Moestl S, Hoffmann F, Honemann J, Rusanov VB.

Aviakosm Ekolog Med. 2021;55(6):23-7. Russian.

Note: ISS results.

 

2

Makarov IA, Voronkov YI, Bogomolov VV, Alferova IV.

Human Physiology. 2021 Dec 16;47(6):612-8.

Note: ISS results.

 

3

Perevedentsev OV, Levanov VM, Orlov OI, Manko OM, Chernogorov RV.

Aviakosm Ekolog Med. 2021;55(6):19-22. Russian.

Note: ISS results. From the abstract: “Integration of artificial intelligence [AI] in cosmonaut’s health monitoring system is a top priority trend in space medicine aimed to enhance crew safety in long-duration space missions. The cutting-edge diagnostic tools aboard the ISS Russian segment such as digital funduscopy, and optic CT of the retina and optic disk allow the collection of statistics of pre- in- and post-flight examinations for calculating the basic block for AI applications.”

 

4

Orlov OI, Popova II, Yu, GR.

Aviakosm Ekolog Med. 2021;55(6):13-8. Russian.

Note: ISS results. From the abstract: “This paper presents the results of research onboard the ISS RS [Russian segment] within the framework of the BIMS space experiment using telemedicine methods for receiving and processing video information and the developed hardware and software—onboard telemedicine kits TBK-1 and TBK-1S.”

 

5

Shumilina IV.

Aviakosm Ekolog Med. 2021;55(6):61-7. Russian.

Note: SIRIUS analog mission. From the abstract: “For the 17- and 120-day isolation campaigns within project SIRIUS, the stock of personal hygiene items (PHIs), underwear and clothes was supplied in compliance with the current ISS rates of consumption. Over 120 questionnaires filled out by the human subjects made possible estimation of the total weight of these provisions in a mission to the Moon, and provided feedback about the hygienic means and methods.”

 

6

Pineguin SA, Dadasheva OA, Mednikova EI, Grushina OA, Spassky AV, Lebedev VM, Ionov SV, Gurieva TS, Sychev VN.

Aviakosm Ekolog Med. 2021;55(6):50-5. Russian.

Note: From the abstract: “Expectation of remote space missions and long-term stay and work on the Moon with the magnetic field 1,000 times weaker than on Earth sets the researchers with the formidable task to investigate effects of the hypomagnetic environment on living organisms. This paper reports data about the liver and spleen development in Japanese quail embryos of various age exposed in a modeled lunar magnetic field.”

 

7

Sihver L, Mortazavi SMJ.

J Biomed Phys Eng. 2021 Dec;11(6):663-74. Review.

Note: From the abstract: “During deep space missions, astronauts are exposed to highly ionizing radiation, including neutrons, protons and heavy ions from galactic cosmic rays (GCR), solar wind (SW) and solar energetic particles (SEP). This increases the risks for cancerogenesis, damages in central nervous system (CNS), cardiovascular diseases, etc. Large SEP events can even cause acute radiation syndrome (ARS). Long term manned deep space missions will therefore require unique radiation protection strategies. Since it has been shown that physical shielding alone is not sufficient, this paper proposes pre-flight screening of the candidates for evaluation of their level of adaptive responses.” This article may be obtained online without charge.

 

8

Berkovich YA, Smolianina SO, Smolianin VG, Morozov YV, Tarakanov IG.

Aviakosm Ekolog Med. 2021;55(6):68-74. Russian.

 

9

Cui Y, Lin F, Wang R, Deng Y, Li Y.

Space Med Med Eng. 2021;2021(6). Chinese. Review.

Note: The specific weightlessness/simulated weightlessness methods are not identified in the available English abstract. From the abstract: “The intact intestinal mucosal barrier is important in resisting the invasion of exogenous antigens into the body. In recent years, the research progress of weightlessness/simulated weightlessness on the function of the intestinal mucosal barrier was reviewed, and the effects of weightlessness/simulated weightlessness on intestinal mucus, intestinal mucosal epithelial barrier, tissue morphology and permeability were reviewed.”

 

10

Jang H, Choi SY, Mun W, Jeong SH, Mitchell RJ.

Microbiol Res. 2021 Dec 6;255:126941. Online ahead of print.

 

11

Shao S, Wu J, Zhou Q, Liu Z, Zhang l.

Space Med Med Eng. 2021;2021(6):439-47. Chinese.

 

12

Ma L, Kong F, Gong Y, Wang Q, Liu J, Sui L.

Front Public Health. 2021 Nov 30;9:759236.

Note: A 3D clinostat was used in this study. This article is part of Research Topic “Medical Application and Radiobiology Research of Particle Radiation” (https://www.frontiersin.org/research-topics/14492/medical-application-and-radiobiology-research-of-particle-radiation#articles). The Research Topic also includes an article from previous Current Awareness List #977 https://doi.org/10.3389/fpubh.2021.733337. Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

13

Orter S, Möstl S, Bachler M, Hoffmann F, Mayer CC, Kaniusas E, Reisinger M, Wassertheurer S, Tank J, Jordan J, Hametner B.

Exp Physiol. 2021 Dec 18. Online ahead of print.

Note: Head-down tilt bedrest study.

 

14

Spitalieri P, Marini M, Scioli MG, Murdocca M, Longo G, Orlandi A, Novelli G, Sangiuolo F.

Cell Mol Bioeng. 2021 Dec;14(6):613-26. Available online 7 June 2021.

Note: A desktop random positioning machine was used in this study. This article may be obtained online without charge.

 

15

Yang J, Geng X, Wei X, Yang M, Jin Z, Wang H, Jiang K, Wang Q, Wang H, Li B, Zhang L, Li Y, Wang Y, Xu Y.

Space Med Med Eng. 2021;2021(6):415-20. Chinese.

 

16

Beke A, Erdos G.

Aviakosm Ekolog Med. 2021;55(6):28-33. Russian.

 

17

Barantseva MY, Ozerov DS, Dadasheva OA.

Aviakosm Ekolog Med. 2021;55(6):56-60. Russian.

Note: Hindlimb unloading study.

 

18

Katuntsev VP, Sukhostavtseva TV, Baranov MV, Kotov AN, Puchkova AA, Tarasenkov GG, Nosovsky ÀÌ.

Aviakosm Ekolog Med. 2021;55(6):42-9. Russian.

Note: Head-up bedrest study.

 

19

Semenov YS, Gorbunova ÀÀ, Diachenko AI.

Aviakosm Ekolog Med. 2021;55(6):34-41. Russian.

Note: Head-down tilt study.

 

20

Brenner E, Houben M, Schukking T, Crowe EM.

Perception. 2021 Dec 17;3010066211065229. Online ahead of print.

Note: From the abstract: “We expect a cursor to move upwards when we push our computer mouse away. Do we expect it to move upwards on the screen, upwards with respect to our body, or upwards with respect to gravity? To find out, we asked participants to perform a simple task that involved guiding a cursor with a mouse. It took participants that were sitting upright longer to reach targets with the cursor if the screen was tilted, so not only directions on the screen are relevant.” This article may be obtained online without charge.

 

21

Zhang Y, Ramasundara SZ, Preketes-Tardiani RE, Cheng V, Lu H, Ju LA.

Front Cardiovasc Med. 2021 Nov 25;8:766513. Mini review.

Note: This article is part of Research Topic “Novel Concepts in Platelet Biology and Anti-Platelet Therapy for Cardiovascular Disease and Beyond”

(https://www.frontiersin.org/research-topics/20786/novel-concepts-in-platelet-biology-and-anti-platelet-therapy-for-cardiovascular-disease-and-beyond#articles). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

22

Zinkin VN, Sheshegov PM.

Aviakosm Ekolog Med. 2021;55(6):5-12. Russian.

Note: From the abstract: “Noise is the leading adverse factor in the day-to-day activities of the Russian force units. External noise, high-intensity in particular, degrades operator’s efficiency increasing the probability of erroneous actions. This paper focuses on noise interference and masking effects on sound transmission and speech communication.”

 

23

Kim JJ, McManus ME, Harris LR.

Perception. 2021 Dec 16:3010066211065673. Online ahead of print.

Note: From the abstract: “Here, we investigate how body orientation relative to gravity affects the perceived size of visual targets.” This article may be obtained online without charge.

 

24

Usher I, Hellyer P, Lee KS, Leech R, Hampshire A, Alamri A, Chari A.

BMJ. 2021 Dec 13;375:e067883. Comparative study.

Note: From the abstract: “Objective: To compare cognitive testing scores in neurosurgeons and aerospace engineers to help settle the age old argument of which phrase—’It’s not brain surgery’ or ‘It’s not rocket science’—is most deserved. …The neurosurgeons showed significantly higher scores than the aerospace engineers in semantic problem solving (difference 0.33, 95% confidence interval 0.13 to 0.52). Aerospace engineers showed significantly higher scores in mental manipulation and attention (−0.29, −0.48 to −0.09).” This article may be obtained online without charge.