Status Report

NASA Spaceline Current Awareness List #920 16 October 2020 (Space Life Science Research Results)

By SpaceRef Editor
October 16, 2020
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SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,



Papers deriving from NASA support:



Santomartino R, Waajen AC, de Wit Wl, Nicholson N, Parmitano L, Loudon C-M, Moeller R, Rettberg P, Fuchs FM, Van Houdt R, Finster K, Coninx I, Krause JS, Koehler A, Caplin N, Zuijderduijn L, Zolesi V, Balsamo M, Mariani A, Pellari SS, Carubia F, Luciani G, Leys N, Doswald-Winkler J, Herová M, Wadsworth J, Everroad RC, Rattenbacher B, Demets R, Cockell CS.

No effect of microgravity and simulated Mars gravity on final bacterial cell concentrations on the International Space Station: Applications to space bioproduction.

Front Microbiol. 2020 Oct 14;11:2414.

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 4.235

Funding: “CSC and RS have been funded by UK Science and Technology Facilities Council under grant ST/R000875/1. RM, FMF, and PR were supported by the DLR grant “DLR-FuE-Projekt ISS LIFE, Programm RF-FuW, Teilprogramm 475.” FMF was also supported by the Helmholtz Space Life Sciences Research School at DLR. RVH and NL received financial support for this study from Belspo and ESA through the PRODEX EGEM/Biorock project contract (PEA 4000011082). ACW was funded by NERC Doctoral Training Partnership grant (NE/L002558/1) and PCDS (Principal’s Career Development Scholarship).” J. Wadsworth and R.C. Everroad are affiliated with NASA Ames Research Center.



Mortreux M, Rosa-Caldwell ME.

Approaching gravity as a continuum using the rat partial weight-bearing model.

Life. 2020 Oct 8;10(10):235. Review.

PI: S.B. Rutkove

Note: From the Introduction: “… the purpose of this review is to summarize the methodology and utility of this rat partial weight bearing (PWB) model in relation to human physiology, summarize what is currently known on the musculoskeletal effects of partial gravity environments, and provide future directions for the use of this model as it relates to spaceflight and physiology.” This article may be obtained online without charge.

Journal Impact Factor: 2.991

Funding: “This work was funded by the National Aeronautics and Space Administration (NASA: 80NSSC19K1598).”



Brandon TA, Stamps BW, Cummings A, Zhang T, Wang X, Jiang D.

Poised potential is not an effective strategy to enhance bio-electrochemical denitrification under cyclic substrate limitations.

Sci Total Environ. 2020 Apr 15;713:136698.

PI: B.W. Stamps, Sloan ISS MoBE Postdoctoral Fellowship

Journal Impact Factor: 6.551

Funding: “Daqian Jiang acknowledges financial support by the United States Department of Agriculture (Award Number 2017-67030-27659) and the National Groundwater Association. Blake W. Stamps acknowledges support by the Sloan Foundation Grant G-2017-9853. This work used the Extreme Science and Engineering Discovery Environment (XSEDE) Jetstream cluster at the Texas Advanced Computing Center, which is supported by National Science Foundation grant number ACI-1548562.”



Parker CW, Singh N, Tighe S, Blachowicz A, Wood JM, Seuylemezian A, Vaishampayan P, Urbaniak C, Hendrickson R, Laaguiby P, Clark K, Clement BG, O’Hara NB, Couto-Rodriguez M, Bezdan D, Mason CE, Venkateswaran K. 

End-to-end protocol for the detection of SARS-CoV-2 from built environments.

mSystems. 2020 Oct 6;5(5):e00771.

Note: This article may be obtained online without charge.

Journal Impact Factor: 6.280

Funding: “This research was supported by the JPL Director Discretionary Funds for COVID-19 projects which also funded a portion of the fellowship of C.W.P., A.B., and J.M.W. We also thank Igor Tulchinsky and the WorldQuant Foundation, Bill Ackman and Olivia Flatto and the Pershing Square Foundation, Ken Griffin and Citadel, Testing for America (501c3), OpenCovidScreen Foundation, the Bert L and N Kuggie Vallee Foundation, the U.S. National Institutes of Health (R01AI125416, R21AI129851, R01AI151059), and the Alfred P. Sloan Foundation (G-2015-13964).” Most of the authors are affiliated with NASA’s Jet Propulsion Laboratory. 



Hezrony BS, Speacht TL, Donahue HJ, Lau AG.

Combined hind limb suspension and sRANK-L on bone strength in mice by finite element analysis: Effects of anatomic model height.

Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:4844-7.

PI: H.J. Donahue

Note: Hindlimb unloading study.

Journal Impact Factor: Not available for this publication

Funding: “Research supported The College of New Jersey’s Mentored Undergraduate Summer Experience (MUSE), the New Jersey Space Grant Consortium (NJSGC), National Space Biomedical Research Institute (grant MA02802) and the NIH (R01 AR068132, R37 AA0011290, and F32 AA023422).”



Shuffler ML, Salas E, Rosen MA.

The evolution and maturation of teams in organizations: Convergent trends in the new dynamic science of teams.

Front Psychol. 2020 Sep 4;11:2128.

PI: M.A. Rosen

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.067

Funding: “This work was partially supported by a grant from the National Aeronautics and Space Administration (#NNX17AB55G; PI: MR), and the National Science Foundation (#1654054, PI: MS).”



Zhen S, Bugbee B.

Substituting far-red for traditionally defined photosynthetic photons results in equal canopy quantum yield for CO2 fixation and increased photon capture during long-term studies: Implications for re-defining PAR.

Front Plant Sci. 2020 Sep 11;11:581156.

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.402

Funding: “This work was supported by the Utah Agricultural Experiment Station, Utah State University; by the NASA-CUBES project award number NNX17AJ31G; and by the USDA-NIFA-SCRI award number 2018-51181-28365 (LAMP Project).”




Other papers of interest:



Caprace D-G, Gontier C, Iranmanesh M, Scoubeau M, Pletser V.

Experimental characterization of weightlessness during glider parabolic flights.

Microgravity Sci Technol. 2020 Oct 10. [Article in Press]

Note: Parabolic flight results. This article may be obtained online without charge.



Malarvizhi S, Hosamani R, Swamy B, Sreejalekshmi K.

Mechano-biological plant responses to microgravity.

Life Sci Space Res. 2020 Oct 10. [Article in Press]   

Note: ISS results. From the abstract: “The current article discusses phenotypic, physiological, biochemical, cell cycle, cell wall changes and molecular responses of plants to microgravity both in real and simulated conditions with the latest literature.”



Nassef MZ, Melnik D, Kopp S, Sahana J, Infanger M, Lützenberg R, Relja B, Wehland M, Grimm D, Krüger M.

Breast cancer cells in microgravity: New aspects for cancer research.

Int J Mol Sci. 2020 Oct 5;21(19):E7345. Review.

Note: Various spaceflight results are discussed, as well as clinostats, the Rotary Cell Culture System, and random positioning machines. This article may be obtained online without charge.



Mendes A.

Space and earth: How gravity affects treatment development.

Br J Community Nurs. 2020 Oct 2;25(10):516-7.



Wheelock CE, Hess HW, Johnson BD, Schlader ZJ, Clemency BM, St James E, Hostler D.

Endurance and resistance respiratory muscle training and aerobic exercise performance in hypobaric hypoxia.

Aerosp Med Hum Perform. 2020 Oct;91(10):776-84.



Orter S, Mostl S, Bachler M, Hoffmann F, Kaniusas E, Reisinger M, Wassertheurer S, Tank J, Hametner B.

Measuring arterial stiffness in a head-down tilt bed rest study: A multisensor approach.

Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:2715-8.

Note: Head-down tilt bed rest study.



Mohebbi A, Amiri P, Kearney RE.

Contributions of vision in human postural control: A virtual reality-based study.

Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:3347-50.



Blakely EA.

The 20th Gray Lecture 2019: Health and heavy ions.

Br J Radiol. 2020 Oct 6. [Epub ahead of print]



Cao J, Zhong L, Feng Y, Qian K, Xiao Y, Wang G, Tu W, Yue L, Zhang Q, Yang H, Jiao Y, Zhu W, Cao J.

Activated beta-catenin signaling ameliorates radiation-induced skin injury by suppressing marvel D3 expression.

Radiat Res. 2020 Oct 12. [Epub ahead of print]



Harbron RW, Pasqual E.

Ionising radiation as a risk factor for lymphoma: A review.

J Radiol Prot. 2020 Oct 5. [Epub ahead of print]

Note: This article may be obtained online without charge.



Liao Z, Liu Z, Gong Z, Hu X, Chen Y, Cao K, Zhang H, Gan L, Chen J, Yang Y, Cai J.

Heat-killed Salmonella typhimurium protects mice against carbon ion radiation.

J Int Med Res. 2020 Oct;48(10):300060520924256.

Note: This article may be obtained online without charge.



Matarèse BFE, Lad J, Seymour C, Schofield PN, Mothersill C.

Bio-acoustic signalling; exploring the potential of sound as a mediator of low-dose radiation and stress responses in the environment.

Int J Radiat Biol. 2020 Oct 7. [Epub ahead of print]



Parisi A, Sato T, Matsuya Y, Kase Y, Magrin G, Verona C, Tran LT, Rosenfeld AB, Bianchi A, Olko P, Struelens L, Vanhavere F.

Development of a new microdosimetric biological weighting function for the RBE10 assessment in case of the V79 cell line exposed to ions from 1H to 238U.

Phys Med Biol. 2020 Oct 8. [Epub ahead of print]



Poirier Y, Becker S, Decesaris C, Culberson W, Draeger E, Gerry AJ, Johnstone CD, Gibbs A, Vujaskovic Z, Jackson IL. 

The impact of radiation energy on dose homogeneity and organ dose in the Göttingen minipig total-body irradiation model.

Radiat Res. 2020 Oct 12. [Epub ahead of print]



Royba E, Repin M, Balajee AS, Shuryak I, Pampou S, Karan C, Brenner DJ, Garty G.

The RABiT-II DCA in the rhesus macaque model.

Radiat Res. 2020 Oct 6. [Epub ahead of print]



Fox EL, Houpt JW, Tsang PS.

Derivation and demonstration of a new metric for multitasking performance.

Hum Factors. 2020 Oct 8. [Epub ahead of print]



Peltier NE, Angelaki DE, DeAngelis GC.

Optic flow parsing in the macaque monkey.

J Vis. 2020 Oct 1;20(10):8.

Note: This article may be obtained online without charge.



Ooka T, Bay J, Takeda T, Honda K, Ikeda T, Tsutsumi T.

Clinical application of 3D-VOG analysis for quantitative evaluation of otolith-ocular reflex in the roll and pitch planes.

Acta Otolaryngol. 2020 Oct 7. [Epub ahead of print]



Sanayi R, Rahimi V, Mohamadkhani R, Hoseinabadi R.

The effect of cognitive tasks on the ocular vestibular evoked myogenic potentials in healthy people.

Iran J Otorhinolaryngol. 2020 Sep;32(112):311-7.

Note: This article may be obtained online without charge.



Han H, Geng Y, Guo L, Yan A, Meyerowitz EM, Liu X, Zhou Y.

The overlapping and distinct roles of HAM family genes in Arabidopsis shoot meristems.

Front Plant Sci. 2020 Sep 4;11:541968.

Note: This article may be obtained online without charge.



Bahmaee H, Owen R, Boyle L, Perrault CM, Garcia-Granada AA, Reilly GC, Claeyssens F.

Design and evaluation of an osteogenesis-on-a-chip microfluidic device incorporating 3D cell culture.

Front Bioeng Biotechnol. 2020 Sep 8;8:557111.

Note: This article may be obtained online without charge.



Bellisle R, Bjune C, Newman D.

Considerations for wearable sensors to monitor physical performance during spaceflight intravehicular activities.

Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:4160-4.



Alcaraz-Mateos E, Turic I, Nieto-Olivares A, Pérez-Ramos M, Poblet E.

Head-tracking as an interface device for image control in digital pathology: A comparative study.

Rev Esp Patol. 2020 Oct-Dec;53(4):213-7.

Note: The NASA Task Load Index was used. This article may be obtained online without charge.



Ventimiglia E, Sindhubodee S, Besombes T, Pauchard F, Quadrini F, Delbarre B, Jiménez Godínez A, Barghouthy Y, Corrales Acosta MA, Kamkoum H, Villa L, Doizi S, Somani BK, Traxer O. 

Operator-assisted vs self-achieved basketing during ureteroscopy: Results from an in vitro preference study.

World J Urol. 2020 Oct 6. [Epub ahead of print]

Note: The NASA Task Load Index was used.

SpaceRef staff editor.