NASA Spaceline Current Awareness List #911 14 August 2020 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Trivedi CB, Stamps BW, Lau GE, Grasby SE, Templeton AS, Spear JR.
Microbial metabolic redundancy is a key mechanism in a sulfur-rich glacial ecosystem.
mSystems. 2020 Aug 4;5(4):e00504-20.
https://pubmed.ncbi.nlm.nih.
PI: B.W. Stamps, Sloan ISS MoBE Postdoctoral Fellowship
Note: This article may be obtained online without charge.
Journal Impact Factor: 6.280
Funding: “This research was funded by a grant (NNX13AJ32G) from the NASA Exobiology and Evolutionary Biology Program to A.S.T. and J.R.S. This work was also supported by NASA Astrobiology Institute Rock Powered Life Grant NNA15BB02A (C.B.T., A.S.T., and J.R.S.) and by funding from the Geological Survey of Canada. B.W.S. was supported by the Sloan Foundation grant G-2017-9853. C.B.T. is currently supported by the Helmholtz Recruiting Initiative (award number I-044-16-01 to Liane G. Benning).”
2
Ramlall V, Thangaraj PM, Meydan C, Foox J, Butler D, Kim J, May B, De Freitas JK, Glicksberg BS, Mason CE, Tatonetti NP, Shapira SD.
Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection.
Nat Med. 2020 Aug 3. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PI: C.E. Mason
Note: This article may be obtained online without charge.
Journal Impact Factor: 30.641
Funding: “This work was funded by US National Institutes of Health grants 5R01GM109018, R21AI147201 and 5U54CA209997 to S.S., R35GM131905 to N.P.T., F30HL140946 to P.T. and equipment grants S10OD012351 and S10OD021764 to the Columbia University Department of Systems Biology. C.E.M. thanks the Scientific Computing Unit, XSEDE Supercomputing Resources, the Starr Cancer Consortium (I13-0052) and funding from the WorldQuant Foundation, the Pershing Square Sohn Cancer Research Alliance, NASA (NNX14AH50G, NNX17AB26G) and the National Institutes of Health (R21AI129851, R01MH117406, R01AI151059).”
3
Mishra PK, Tandon R, Byrareddy SN.
Diabetes and COVID-19 risk: A miRNA perspective.
Am J Physiol Heart Circ Physiol. 2020 Aug 7. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PI: R. Tandon
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.553
Funding: “This work was supported, in part by the National Institutes of Health (NIH) Grant HL-113281, and a grant from and National Institute of General Medical Sciences, 1U54GM115458, and the UNMC Center for Heart and Vascular Research to PKM, National Aeronautics and Space Administration grant 80NSSC19K1603 and the University of Mississippi Medical Center COVID-19 Fund to RT, and NIH grant P30MH062261, and Frances E. Lageschulte and Evelyn B. Weese New Frontiers in Medical Research Fund to SNB. The content is solely the responsibility of the authors and does not necessarily represents the official views of the grant institutions.”
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Other papers of interest:
1
Kaplan F, Shapiro-Ilan D, Schiller KC.
Dynamics of entomopathogenic nematode foraging and infectivity in microgravity.
npj Microgravity. 2020 Aug 10;6(1):20.
https://www.nature.com/
Note: ISS results. This article may be obtained online without charge.
2
Bimpong-Buta NY, Muessig JM, Knost T, Masyuk M, Binneboessel S, Nia AM, Kelm M, Jung C.
Comprehensive analysis of macrocirculation and microcirculation in microgravity during parabolic flights.
Front Physiol. 2020 Aug 13;11:960.
https://www.frontiersin.org/
Note: Parabolic flight results. This article may be obtained online without charge.
3
Patel S.
The effects of microgravity and space radiation on cardiovascular health: From low-Earth orbit and beyond.
Int J Cardiol Heart Vasc. 2020 Oct 1;30:100595. Review. Epub 2020 Jul 30.
http://www.sciencedirect.com/
Note: Long-duration spaceflight studies are reviewed. This article may be obtained online without charge.
4
Cal R, Davis H, Kerr A, Wall A, Molloy B, Chauhan S, Trajkovic S, Holyer I, Adelfio A, Khaldi N.
Preclinical evaluation of a food-derived functional ingredient to address skeletal muscle atrophy.
Nutrients. 2020 Jul 29;12(8):E2274.
https://pubmed.ncbi.nlm.nih.
Note: Hindlimb unloading study. From the abstract: “In vitro testing in murine skeletal muscle cells and human macrophages was carried out to determine the effect of a hydrolysate derived from Vicia faba (PeptiStrong: NPN_1) against phosphorylated S6, atrophy gene expression, and tumour necrosis factor alpha (TNF-α) secretion, respectively.” This article may be obtained online without charge.
5
Pollmann C, Haug M, Reischl B, Prölß G, Pöschel T, Rupitsch SJ, Clemen CS, Schröder R, Friedrich O.
Growing old too early: Skeletal muscle single fiber biomechanics in ageing R349P desmin knock-in mice using the MyoRobot technology.
Int J Mol Sci. 2020 Jul 31;21(15):E5501.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
6
Sharlo KA, Paramonova, II, Lvova ID, Vilchinskaya NA, Bugrova AE, Shevchenko TF, Kalamkarov GR, Shenkman BS.
NO-dependent mechanisms of myosin heavy chain transcription regulation in rat soleus muscle after 7-days hindlimb unloading.
Front Physiol. 2020 Jul 10;11:814.
https://pubmed.ncbi.nlm.nih.
Note: Hindlimb unloading study. This article may be obtained online without charge.
7
Stokes T, Timmons JA, Crossland H, Tripp TR, Murphy K, McGlory C, Mitchell CJ, Oikawa SY, Morton RW, Phillips BE, Baker SK, Atherton PJ, Wahlestedt C, Phillips SM.
Molecular transducers of human skeletal muscle remodeling under different loading states.
Cell Rep. 2020 Aug 4;32(5):107980.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
8
Tarantino U, Cariati I, Marini M, D’Arcangelo G, Tancredi V, Primavera M, Iundusi R, Gasbarra E, Scimeca M.
Effects of simulated microgravity on muscle stem cells activity.
Cell Physiol Biochem. 2020 Aug 5;54(4):736-47.
https://pubmed.ncbi.nlm.nih.
Note: A random positioning machine was used. This article may be obtained online without charge.
9
Virgilio KM, Jones BK, Miller EY, Ghajar-Rahimi E, Martin KS, Peirce SM, Blemker SS.
Computational models provide insight into in vivo studies and reveal the complex role of fibrosis in mdx muscle regeneration.
Ann Biomed Eng. 2020 Aug 3. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
10
Ohsugi Y, Katagiri S, Hirota T, Niimi H, Hatasa M, Watanabe K, Shimohira T, Mizutani K, Kitazawa M, Matsuzawa A, Kadokura H, Yokose S, Iwata T, Aoki A.
Laser irradiation decreases sclerostin expression in bone and osteogenic cells.
FASEB J. 2020 Aug 5. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
11
Peck K, Russo F, Campos JL, Keshavarz B.
Examining potential effects of arousal, valence, and likability of music on visually induced motion sickness.
Exp Brain Res. 2020 Aug 5. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
12
Teaford MA, Cook HE 4th, Hassebrock JA, Thomas RD, Smart LJ Jr.
Perceptual validation of nonlinear postural predictors of visually induced motion sickness.
Front Psychol. 2020 Jul 15;11:1533.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
13
Tafforin C.
Humans’ 3R-adaptation for space colonization.
J Humanit Soc Sci Stud. 2020 Jul;2(4):72-82.
https://www.jhsss.org/vol-2-
Note: From the abstract: “We observed, described and quantified the subjects’ orientations, actions, interactions, expressions and positions with the ethological method, science of behavior, implemented in parabolic flight, in orbital flight, during Sirius-19, Mars-500 and CELSS-180 experiments, and at Concordia polar station. We found that the physical and social environment had impacts on the motor, social and cultural behaviors. The behavioral strategies developed over short-term to extended periods of time are based on new Referentials, Rhythms and Rituals of self-organized crews for autonomous missions to the Moon or Mars.” This article may be obtained online without charge; the URL goes to the table of contents and this is the 8th article from the top.
14
Weber B, Panzirsch M, Stulp F, Schneider S.
Sensorimotor performance and haptic support in simulated weightlessness.
Exp Brain Res. 2020 Aug 7. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: Water immersion was used. This article may be obtained online without charge.
15
Lu Z, Wang J, Qu L, Kan G, Zhang T, Shen J, Li Y, Yang J, Niu Y, Xiao Z, Li Y, Zhang X.
Reactive mesoporous silica nanoparticles loaded with limonene for improving physical and mental health of mice at simulated microgravity condition.
Bioact Mater. 2020 Dec;5(4):1127-37. Epub 2020 Jul 22.
https://pubmed.ncbi.nlm.nih.
Note: Hindlimb unloading study. This article may be obtained online without charge.
16
Armougum A, Gaston-Bellegarde A, Joie-La Marle C, Piolino P.
Physiological investigation of cognitive load in real-life train travelers during information processing.
Appl Ergon. 2020 Aug 4;89:103180. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: The NASA Task Load Index was used.
17
Higuchi M, Abe T, Hotta K, Morita K, Miyata H, Furumido J, Iwahara N, Kon M, Osawa T, Matsumoto R, Kikuchi H, Kurashima Y, Murai S, Aydin A, Raison N, Ahmed K, Khan MS, Dasgupta P, Shinohara N.
Development and validation of a porcine organ model for training in essential laparoscopic surgical skills.
Int J Urol. 2020 Aug 3. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: The NASA Task Load Index was used. This article may be obtained online without charge.
18
Prell R, Opatz O, Merati G, Gesche B, Gunga HC, Maggioni MA.
Heart rate variability, risk-taking behavior and resilience in firefighters during a simulated extinguish-fire task.
Front Physiol. 2020 Jul 10;11:482.
https://pubmed.ncbi.nlm.nih.
Note: The NASA Task Load Index was used. This article may be obtained online without charge.
