NASA Spaceline Current Awareness List #909 31 July 2020 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Deshpande N, Laurie SS, Lee SMC, Miller CA, Mulavara AP, Peters BT, Reschke MF, Stenger MB, Taylor LC, Wood SJ, Clément GR, Bloomberg JJ.
Vestibular and cardiovascular responses after long-duration spaceflight.
Aerosp Med Hum Perform. 2020 Aug 1;91(8):621-7.
https://pubmed.ncbi.nlm.nih.
PI: J.J. Bloomberg
Note: ISS results.
Journal Impact Factor: 0.889
Funding: “This work was supported by the Human Health and Countermeasure Element of the Human Research Program at the NASA Johnson Space Center.”
2
Lee SMC, Martin DS, Miller CA, Scott JM, Laurie SS, Macias BR, Mercaldo ND, Ploutz-Snyder L, Stenger MB.
Venous and arterial responses to partial gravity.
Front Physiol. 2020 Jul 28;11:863.
https://www.frontiersin.org/
PI: L. Ploutz-Snyder
Note: Parabolic flight results. This article may be obtained online without charge.
Journal Impact Factor: 3.367
Funding: “This research was funded by NASA’s Human Research Program and by NASA NNX16AO73G (LP-S).”
3
Alder-Rangel A, Idnurm A, Brand AC, Brown AJP, Gorbushina A, Kelliher CM, Campos CB, Levin DE, Bell-Pedersen D, Dadachova E, Bauer FF, Gadd GM, Braus GH, Braga GUL, Brancini GTP, Walker GM, Druzhinina I, Pócsi I, Dijksterhuis J, Aguirre J, Hallsworth JE, Schumacher J, Wong KH, Selbmann L, Corrochano LM, Kupiec M, Momany M, Molin M, Requena N, Yarden O, Cordero RJB, Fischer R, Pascon RC, Mancinelli RL, Emri T, Basso TO, Rangel DEN.
The Third International Symposium on Fungal Stress – ISFUS.
Fungal Biol. 2020 May;124(5):235-52.
https://pubmed.ncbi.nlm.nih.
PI: R. Mancinelli
Note: From the abstract: “The International Symposium on Fungal Stress (ISFUS) brings together leading scientists from around the world who research fungal stress. This article discusses presentations given at the third ISFUS, held in São José dos Campos, São Paulo, Brazil in 2019, thereby summarizing the state-of-the-art knowledge on fungal stress…” Dr. Mancinelli’s presentation, ‘Microbes in Space,’ part of the section on Fungal Biology in Extreme Environments, is summarized on pages 242-243.
Journal Impact Factor: 2.789
Funding: “…RLM – The NASA Cooperative agreement [NNX12AD05A] and NASA Grant [80NSSC18K0751]…”
4
Gore MO, Ayers CR, Khera A, deFilippi CR, Wang TJ, Seliger SL, Nambi V, Selvin E, Berry JD, Hundley WG, Budoff M, Greenland P, Drazner MH, Ballantyne CM, Levine BD, de Lemos JA.
Combining biomarkers and imaging for short-term assessment of cardiovascular disease risk in apparently healthy adults.
J Am Heart Assoc. 2020 Jul 23. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PI: J.A. de Lemos
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.605
Funding: “This study was supported by National Space Biomedical Research Institute research grant CA03801 (to de Lemos). Gore was supported by a career development grant (K23-HL131939) from the National Heart, Lung, and Blood Institute (NHLBI), by a University of Colorado School of Medicine Fund to Retain Clinical Scientists research award from the Doris Duke Charitable Foundation, and by a Pilot Study Research Grant for Junior Investigators from Denver Health and Hospital Authority. The MESA study was supported by contracts HHSN268201500003I, N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168 and N01-HC-95169 from NHLBI, and by grants UL1-TR-000040, UL1-TR-001079, and UL1-TR-001420 from the National Center for Advancing Translational Sciences). The DHS was supported by a grant from the Donald W. Reynolds Foundation and by a grant from the National Center for Advancing Translational Sciences (UL1TR001105). The ARIC study was supported by contracts HHSN268201700001I, HHSN268201700002I, HHSN268201700003I, HHSN268201700005I, and HHSN268201700004I from NHLBI. Selvin was supported by grant R01-DK089174 from the National Institute of Diabetes and Digestive and Kidney Diseases. Budoff was supported by grant R01-HL071739 from NHLBI. Drazner was supported by the James M. Wooten Chair in Cardiology from UT Southwestern Medical Center. Ballantyne was supported by grant R01-HL134320 from NHLBI. Levine was supported by grants P01-HL137630 from NHLBI and 14SFRN20510023 from the American Heart Association.”
5
Badran BW, Caulfield KA, Lopez JW, Cox C, Stomberg-Firestein S, DeVries WH, McTeague LM, George MS, Roberts D.
Personalized TMS helmets for quick and reliable TMS administration outside of a laboratory setting.
Brain Stimul. 2020 May-Jun;13(3):551-3.
https://pubmed.ncbi.nlm.nih.
PI: D. Roberts
Note: This article may be obtained online without charge.
Journal Impact Factor: 6.565
Funding: “This work is supported by the Translational Research Institute for Space Health (TRISH) through NASA NNX16AO69A, National Center of Neuromodulation for Rehabilitation (NC NM4R) (5P2CHD086844-03), and the COBRE Brain Stimulation Core (5P20GM109040-04).”
6
Cahoon DS, Shukitt-Hale B, Bielinski DF, Hawkins EM, Cacioppo AM, Rabin BM.
Effects of partial- or whole-body exposures to 56Fe particles on brain function and cognitive performance in rats.
Life Sci Space Res. 2020 Nov;27:56-63. Epub 2020 Jul 24.
http://www.sciencedirect.com/
PI: B.M. Rabin
Journal Impact Factor: 2.453
Funding: “This research was supported by NASA Grant NNX16AE06G.”
7
Wong L, Pradhan S, Karasinski J, Hu C, Strangman G, Ivkovic V, Arsintescu L, Flynn-Evans E.
Performance on the Robotics On-Board Trainer (ROBoT-r) spaceflight simulation during acute sleep deprivation.
Front Neurosci. 2020 Jul 21;14:697.
https://www.frontiersin.org/
PI: E.E. Flynn-Evans
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.707
Funding: “This study was funded by the NASA Human Research Program, Human Factors and Behavioral Health Element and the San José State University Research Foundation.”
8
Feltz DL, Hill CR, Samendinger S, Myers ND, Pivarnik JM, Winn B, Ede A, Ploutz-Snyder L.
Can simulated partners boost workout effort in long-term exercise?
J Strength Cond Res. 2020 Jul 23. [Epub ahead of print]
https://journals.lww.com/nsca-
PI: D.L. Feltz
Journal Impact Factor: 2.973
Funding: “This study was funded by NASA/National Space Biomedical Research Institute, MA03401.”
9
Hilleary R, Paez-Valencia J, Vens C, Toyota M, Palmgren M, Gilroy S.
Tonoplast-localized Ca2+ pumps regulate Ca2+ signals during pattern-triggered immunity in Arabidopsis thaliana.
Proc Natl Acad Sci U S A. 2020 Jul 20. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PI: S. Gilroy
Note: This article may be obtained online without charge.
Journal Impact Factor: 9.412
Funding: “This work was supported by grants from the National Science Foundation (MCB1329723, MCB1614965, and IOS1557899); the National Aeronautics and Space Administration (NNX13AM50G, NNX14AT25G, 80NSSC19K0126); the Japan Science and Technology Agency PRESTO, Japan Society for the Promotion of Science KAKENHI (17H050077, 18H04775, and 18H05491); and the University of Wisconsin–Madison Graduate School. R.H. was supported by an National Science Foundation Graduate Research fellowship and the University of Wisconsin–Madison Graduate School.”
10
Riccio G, Au R, van Emmerik R, Eslami M.
Situated precision healthcare in the smart medical home: Bringing NASA’s research strategy down to Earth.
Adv Geriatr Med Res. 2020 Jun 29;2(3):e200017.
https://agmr.hapres.com/htmls/
PI: G. Riccio
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This work was partially supported by the Translational Research Institute for Space Health through NASA Cooperative Agreement NNX16AO69A in 2019. Under that agreement, the current work has more specifically been influenced by a grant for Translational Research for Autonomous Care Coordination to which Mark Shelhamer and Jayant Menon have made essential contributions as co-Investigators in that grant and in their independent work. RA has funding from the National Institute on Aging (AG016495, AG013846, AG049810, AG062109) that influenced the conceptual contributions to this article. RVE has funding from National Institutes of Health (DC012057-06) and Department of Defense, Congressionally Directed Medical Research Program on Multiple Sclerosis (grant #W81XWH-16-1-0351).”
______________________________
Other papers of interest:
1
Siddiqui R, Akbar N, Ahmed Khan N.
Gut microbiome and human health under the space environment.
J Appl Microbiol. 2020 Jul 21. [Epub ahead of print] Review.
https://pubmed.ncbi.nlm.nih.
Note: ISS studies are discussed. This article may be obtained online without charge.
2
Li W, Lan D, Wang Y.
Exploration of direct-ink-write 3D printing in space: Droplet dynamics and patterns formation in microgravity.
Microgravity Sci Technol. 2020 Jul 25. [Article in Press]
https://link.springer.com/
Note: SJ-10 Chinese satellite results. From the abstract: “As a simple, fast and effective 3D printing method, direct-ink-writing (DIW) has potential applications in repairing the circuit board in orbit, printing the wearable devices for the astronaut, and producing the solar cells for the energy supply in space. To expand the DIW technology to space, we designed the colloidal material box (CMB) as the prototype printer of DIW and verified its applicability in the Chinese SJ-10 satellite.”
3
Ohmichi Y, Ohmichi M, Tashima R, Osuka K, Fukushige K, Kanikowska D, Fukazawa Y, Yawo H, Tsuda M, Naito M, Nakano T.
Physical disuse contributes to widespread chronic mechanical hyperalgesia, tactile allodynia, and cold allodynia through neurogenic inflammation and spino-parabrachio-amygdaloid pathway activation.
Pain. 2020 Aug;161(8):1808-23.
https://pubmed.ncbi.nlm.nih.
Note: Cast immobilization was used.
4
Sallinen M, van Dijk H, Aeschbach D, Maij A, Åkerstedt T.
A large-scale European Union study of aircrew fatigue during long night and disruptive duties.
Aerosp Med Hum Perform. 2020 Aug 1;91(8):628-35.
https://pubmed.ncbi.nlm.nih.
5
Wells JN, Buschauer R, Mackens-Kiani T, Best K, Kratzat H, Berninghausen O, Becker T, Gilbert W, Cheng J, Beckmann R.
Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
PLoS Biol. 2020 Jul 20;18(7):e3000780.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
6
Lautridou J, Dugrenot E, Amérand A, Guernec A, Pichavant-Rafini K, Goanvec C, Inizan M, Albacete G, Belhomme M, Galinat H, Lafère P, Balestra C, Moisan C, Buzzacott P, Guerrero F.
Physiological characteristics associated with increased resistance to decompression sickness in male and female rats.
J Appl Physiol (1985). 2020 Jul 23. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
7
Chen Y, Wu B, Zhang C, Fan Z, Chen Y, Xin B, Xie Q.
Current progression: Application of high-throughput sequencing technique in space microbiology.
Biomed Res Int. 2020 Jun 20;2020:4094191. Review.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
8
Constantini K, Bouillet AC, Wiggins CC, Martin BJ, Chapman RF.
Ventilatory responsiveness during exercise and performance impairment in acute hypoxia.
Med Sci Sports Exerc. 2020 Jul 15. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
9
Kashirina DN, Brzhozovskiy AG, Pastushkova LK, Kononikhin AS, Borchers CH, Nikolaev EN, Larina IM.
Semiquantitative proteomic research of protein plasma profile of volunteers in 21-day head-down bed rest.
Front Physiol. 2020 Jul 24;11:678.
https://www.frontiersin.org/
Note: Head-down tilt bed rest study. This article may be obtained online without charge.
10
Xu D, Tremblay MF, Verma AK, Tavakolian K, Goswami N, Blaber AP.
Cardio-postural interactions and muscle-pump baroreflex are severely impacted by 60-day bedrest immobilization.
Sci Rep. 2020 Jul 21;10(1):12042.
https://pubmed.ncbi.nlm.nih.
Note: Head-down tilt bed rest study. This article may be obtained online without charge.
11
Berezovskaya AS, Tyganov SA, Nikolaeva SD, Naumova AA, Merkulyeva NS, Shenkman BS, Glazova MV.
Dynamic foot stimulations during short-term hindlimb unloading prevent dysregulation of the neurotransmission in the hippocampus of rats.
Cell Mol Neurobiol. 2020 Jul 18. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: Hindlimb unloading study.
12
Kovalev VS, Manukovsky NS, Tikhomirov AA.
Bioregenerative life support space diet and nutrition requirements: Still seeking accord.
Life Sci Space Res. 2020 Jul 27. [Article in Press]
http://www.sciencedirect.com/
13
Goulding RP, Okushima D, Marwood S, Poole DC, Barstow TJ, Lei TH, Kondo N, Koga S.
Impact of supine exercise on muscle deoxygenation kinetics heterogeneity: Mechanistic insights into slow pulmonary oxygen uptake dynamics.
J Appl Physiol (1985). 2020 Jul 23. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
14
Alkner BA, Bring DK-I.
Erratum: [Muscle activation during gravity-independent resistance exercise compared to common exercises].
Aerosp Med Hum Perform. 2020 Aug 1;91(8):684.
https://pubmed.ncbi.nlm.nih.
Note: “In Table I , the SD value for FW Ecc Peak Force value should be 748 (and not 7489). The EMG data are not affected by this and it does not affect the results, discussion, or conclusion of the paper.” The original paper was cited in SPACELINE Current Awareness List #851, 31 May 2019: Alkner BA, Bring DK. Muscle activation during gravity-independent resistance exercise compared to common exercises. Aerosp Med Hum Perform. 2019 Jun 1;90(6):506-12. https://www.ncbi.nlm.nih.gov/
15
Rindom E, Herskind J, Blaauw B, Overgaard K, Vissing K, de Paoli FV.
Concomitant excitation and tension development are required for myocellular gene expression and protein synthesis in rat skeletal muscle.
Acta Physiol (Oxf). 2020 Jul 20. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
16
Cucinotta FA, Cacao E, Kim M-HY, Saganti PB.
Benchmarking risk predictions and uncertainties in the NSCR model of GCR cancer risks with revised low LET risk coefficients.
Life Sci Space Res. 2020 Jul 26. [Article in Press]
http://www.sciencedirect.com/
17
Kinoshita K, Zabarmawi Y.
Ionization clustering on charged particle tracks as a seed for biologically relevant radiation effects.
Phys Rev E. 2020 Jun;101(6-1):062411.
https://pubmed.ncbi.nlm.nih.
18
Tong L, Wang Y, Wang J, He F, Zhai J, Bai J, Zhu G.
Radiation alters osteoclastogenesis by regulating the cytoskeleton and lytic enzymes in RAW 264.7 cells and mouse bone marrow-derived macrophages.
Int J Radiat Biol. 2020 Jul 20. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
19
Yang ZY, Sheu RJ.
A comprehensive approach for estimating collective and average effective doses of galactic cosmic radiation received by pilots.
Health Phys. 2020 Jul 15. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
20
Rennie KJ, Meredith FL.
Persistent and resurgent Na+ currents in vestibular calyx afferents.
J Neurophysiol. 2020 Jul 15. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
21
Chang EY-W.
From aviation tourism to suborbital space tourism: A study on passenger screening and business opportunities.
Acta Astronaut. 2020 Jul 25. [Article in Press]
http://www.sciencedirect.com/
Note: From the abstract: “Referring to the possible or potential effects of reusable suborbital launch vehicle (RSLV) trajectory dynamics on the neuro-vestibular system of passenger, this paper studied and discussed the pre-flight passenger screening contents and the related business opportunities for suborbital space tourism (SST).”
22
Postiglione AE, Muday GK.
The role of ROS homeostasis in ABA-induced guard cell signaling.
Front Plant Sci. 2020 Jun 30;11:968. Review.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
23
Yang P, Wen Q, Yu R, Han X, Deng XW, Chen H.
Light modulates the gravitropic responses through organ-specific PIFs and HY5 regulation of LAZY4 expression in Arabidopsis.
Proc Natl Acad Sci U S A. 2020 Jul 20. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
