NASA Spaceline Current Awareness List #903 12 June 2020 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website athttps://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Smith MG, Kelley M, Basner M.
A brief history of spaceflight from 1961 to 2020: An analysis of missions and astronaut demographics.
Acta Astronaut. 2020 Oct 1;175:290-9. Epub 2020 Jun 3.
http://www.sciencedirect.com/
PI: M. Basner
Note: From the Introduction: “In an attempt to uncover trends in astronaut demographics over time and between space agencies, this paper presents a historical analysis of publicly available data on all human spaceflights, up to and including the landing of Soyuz MS-13 on February 6th, 2020.”
Journal Impact Factor: 2.482
Funding: “This research was supported by the National Aeronautics and Space Administration (NASA) through grants NNX14AM81G, 80NSSC19K1046 and NNX16AI53G.”
2
DeWitt JM, Benton ER.
Shielding effectiveness: A weighted figure of merit for space radiation shielding.
Appl Radiat Isot. 2020 Jul;161:109141. Epub 2020 Mar 30.
https://pubmed.ncbi.nlm.nih.
PI: E.R. Benton
Journal Impact Factor: 1.343
Funding: “This work was supported in part by NASA MSFC Grants NAG8-01899 and NAG8-01944.”
3
Edmondson EF, Gatti DM, Ray FA, Garcia EL, Fallgren CM, Kamstock DA, Weil MM.
Genomic mapping in outbred mice reveals overlap in genetic susceptibility for HZE ion- and γ-ray-induced tumors.
Sci Adv. 2020 Apr;6(16):eaax5940.
https://pubmed.ncbi.nlm.nih.
PI: M.M. Weil; M.M. Weil/NSCOR
Note: This article may be obtained online without charge.
Journal Impact Factor: 12.530
Funding: “This work was supported by NASA grants NNX12AB54G and NASA NNX15AK13G, and NIH training grant 4T32OD010437-15 (E.F.E.) and R01GM070683 (D.M.G.). Additional funding came from NIH AA13484; NIH R24 AA020245; and NIH U01 AA013519 for the HS/Npt mice.”
4
Huang EG, Sachs RK.
Commentary on “Simulating galactic cosmic ray effects: Synergy modeling of murine tumor prevalence after exposure to two one-ion beams in rapid sequence.”
Life Sci Space Res. 2020 Apr 19. [Article in Press]
http://www.sciencedirect.com/
PI: E.A. Blakely
Note: This commentary supplements the article: Huang EG, Wang R, Xie L, Chang P, Yao G, Zhang B, Ham DW, Lin Y, Blakely E, Sachs R. Simulating galactic cosmic ray effects: Synergy modeling of murine tumor prevalence after exposure to two one-ion beams in rapid sequence. Life Sci Space Res. 2020 May;25:107-18. Epub Jan 7. https://pubmed.ncbi.nlm.nih.
Journal Impact Factor: 2.066
Funding: From the original article: “EAB, PYC, and RKS gratefully acknowledge funding support from NASA [Grant no. NNJ16HP22I (EAB)], under the auspices of the U.S. Department of Energy Office of Science under Contract No. DE-AC02-05CH11231.”
5
Anderson AP, Covington KB, Rieke CC, Fellows AM, Buckey JC.
Detecting changes in distortion product otoacoustic emission maps using statistical parametric mapping and random field theory.
J Acoust Soc Am. 2020 May;147(5):3444.
https://pubmed.ncbi.nlm.nih.
PIs: J.C. Buckey; A.P. Anderson, NSBRI Postdoctoral Fellowship Program
Journal Impact Factor: 1.819
Funding: “This work was supported by the National Space Biomedical Research Institute through Grants Nos. PF04103 and CA03401. It was also supported by the Office of Naval Research Grant No. N00014-14-1-0250. Additional support was provided by the Undergraduate Research Opportunities Program at the University of Colorado Boulder.”
6
Anderson A, Boppana A, Wall R, Acemyan CZ, Adolf J, Klaus D.
Framework for developing alternative reality environments to engineer large, complex systems.
Virtual Real. 2020 May 23. [Article in Press]
https://link.springer.com/
PI: A. Anderson
Journal Impact Factor: 2.906
Funding: “This work was funded by the NASA Human Research Program, Grant 80NSSC18K0198.”
7
Anava S, Neuhof M, Gingold H, Sagy O, Munters A, Svensson EM, Afshinnekoo E, Danko D, Foox J, Shor P, Riestra B, Huchon D, Mason CE, Mizrahi N, Jakobsson M, Rechavi O.
Illuminating genetic mysteries of the Dead Sea Scrolls.
Cell. 2020 May 15. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PI: C.E. Mason
Note: This article may be obtained online without charge.
Journal Impact Factor: 36.216
Funding: “We would like to thank the Epigenomics Core Facility at Weill Cornell Medicine as well as the Bert L. and N. Kuggie Vallee Foundation, the WorldQuant Foundation, NASA (NNX14AH50G, 15-15Omni2-0063), the Alfred P. Sloan Foundation (G-2015-13964), the Knut and Alice Wallenberg Foundation, and the Göran Gustavsson Foundation. Sequencing was performed at SciLifeLab’s National Genomics Infrastructure (NGI), Uppsala, Sweden. Computations were performed at the Swedish National Infrastructure for Computing (SNIC-UPPMAX) and with help and support from the HPC team at the TAU Computational Center. E.M.S. is supported by Formas (2011-1138). Research regarding the Songs is supported by the Israel Science Foundation (723/13). O.R. is supported by the Adelis Foundation (01430001000). This work was funded by the generosity of Eric and Wendy Schmidt by recommendation of the Schmidt Futures program (590772).”
______________________________
Other papers of interest:
1
Bailey DM, Lanéelle D, Trihan J-E, Marchi N, Stacey BS, Tamiya K, Washio T, Tuaillon E, Hirtz C, Lehmann S, Ogoh S, Normand H.
Gravitational transitions increase posterior cerebral perfusion and systemic oxidative-nitrosative stress: Implications for neurovascular unit integrity.
Neuroscience. 2020 Jun 2. [Article in Press]
http://www.sciencedirect.com/
Note: Parabolic flight results.
2
Squire T, Ryan A, Bernard S.
Radioprotective effects of induced astronaut torpor and advanced propulsion systems during deep space travel.
Life Sci Space Res. 2020 Jun 10. [Article in Press]
http://www.sciencedirect.com/
Note: The authors investigated how the circadian clock and body temperature may contribute to radioprotection during human torpor on deep space missions and estimated radiation dose received by astronauts during a transit to Mars with varying propulsion systems.
3
Milojevic T, Weckwerth W.
Molecular mechanisms of microbial survivability in outer space: A systems biology approach.
Front Microbiol. 2020 May 15;11:923.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
4
Paton S, Moore G, Campagnolo L, Thomas P.
Antimicrobial surfaces for use on inhabited space craft: A review.
Life Sci Space Res. 2020 Jun 10. [Article in Press]
http://www.sciencedirect.com/
Note: From the abstract: “This review aims to examine both terrestrial and space-based experiments that have aimed to reduce microbial growth which are applicable to the unique conditions of crewed spacecraft.”
5
Rytter N, Piil P, Carter H, Nyberg M, Hellsten Y, Gliemann L.
Microvascular function is impaired after short-term immobilization in healthy men.
Med Sci Sports Exerc. 2020 Apr 20. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: The method used for immobilization is not identified in the available abstract.
6
Solbiati S, Landreani F, Turcato M, Martin-Yebra A, Costantini L, Vaida P, Caiani EG.
Analysis of changes in cardiac circadian rhythms of RR and QT induced by a 60-day head-down bed rest with and without nutritional countermeasure.
Eur J Appl Physiol. 2020 Jun 3. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: Head-down tilt bed rest study.
7
Goropashnaya AV, Barnes BM, Fedorov VB.
Transcriptional changes in muscle of hibernating arctic ground squirrels (Urocitellus parryii): Implications for attenuation of disuse muscle atrophy.
Sci Rep. 2020 Jun 2;10(1):9010.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
8
Nishikawa K, Lindstedt SL, Hessel A, Mishra D.
N2A titin: Signaling hub and mechanical switch in skeletal muscle.
Int J Mol Sci. 2020 Jun 1;21(11):E3974. Review.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
9
Okabe H, Ohira T, Kawano F, Ohira L, Ohira T, Kamibayashi K, Goto K, Naito H, Ohira Y.
Role of active plantar-flexion and/or passive dorsi-flexion of ankle joints as the countermeasure for unloading-related effects in human soleus.
Acta Astronaut. 2020 Oct;175:174-8. Epub 2020 May 28.
http://www.sciencedirect.com/
10
Sinha U, Malis V, Csapo R, Narici M, Sinha S.
Magnetic resonance imaging based muscle strain rate mapping during eccentric contraction to study effects of unloading induced by unilateral limb suspension.
Eur J Transl Myol. 2020 Apr 7;30(1):8935.
https://pubmed.ncbi.nlm.nih.
Note: A unilateral limb suspension system was used. This article may be obtained online without charge.
11
Sjöberg M, Berg HE, Norrbrand L, Andersen MS, Gutierrez-Farewik EM, Sundblad P, Eiken O.
Influence of gravity on biomechanics in flywheel squat and leg press.
Sports Biomech. 2020 Jun 5. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: A flywheel resistance system was used. This article may be obtained online without charge.
12
Jähn-Rickert K, Wölfel EM, Jobke B, Riedel C, Hellmich M, Werner M, McDonald MM, Busse B.
Elevated bone hardness under denosumab treatment, with persisting lower osteocyte viability during discontinuation.
Front Endocrinol (Lausanne). 2020 May 15;11:250.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
13
Kalapodis N, Kampas G, Ktenidou O-J.
A review towards the design of extraterrestrial structures: From regolith to human outposts.
Acta Astronaut. 2020 May 26. [Article in Press]
http://www.sciencedirect.com/
14
Casini AEM, Mittler P, Cowley A, Schlüter L, Faber M, Fischer B, von der Wiesche M, Maurer MM.
Lunar analogue facilities development at EAC: The LUNA project.
J Space Safety Eng. 2020 Jun 6. [Article in Press]
http://www.sciencedirect.com/
Note: The European Astronaut Center (EAC) in Cologne is developing the LUNA artificial lunar analogue facility and a habitation module called the Future Lunar EXploration Habitat (FLEXHab). The LUNA testbed will be used for astronaut training and is expected to be completed in 2021.
15
Velichko VV, Tikhomirov AA, Ushakova SA, Trifonov SV, Gribovskaya IV.
The effect of supplementation of the soil-like substrate with wheat straw mineralized to different degrees on wheat productivity in closed ecosystems.
Life Sci Space Res. 2020 Jun 10. [Article in Press]
http://www.sciencedirect.com/
16
Melikhov AS, Bolodyan IA, Tanklevskiy LT.
Fire safety provision in inhabited pressurized compartments of spacecraft during a flight in simulated gravity.
Acta Astronaut. 2020 May 27. [Article in Press]
http://www.sciencedirect.com/
Note: The method used for microgravity stimulation is not identified in the available abstract.
17
Hafiz P, Bardram JE.
The Ubiquitous Cognitive Assessment Tool for Smartwatches: Design, implementation, and evaluation study.
JMIR Mhealth Uhealth. 2020 Jun 1;8(6):e17506.
https://pubmed.ncbi.nlm.nih.
Note: The NASA Task Load Index was used. This article may be obtained online without charge.
18
Schlager D, Obaid MA, Hein S, Wilhelm K, Schoenthaler M, Gratzke C, Miernik A, Schoeb DS.
Current disposable ureteroscopes – Performance and limitations in a standardized kidney model.
J Endourol. 2020 May 30. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: The NASA Task Load Index was used.
