NASA Spaceline Current Awareness List #895 16 April 2020 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Kramer LA, Hasan KM, Stenger MB, Sargsyan A, Laurie SS, Otto C, Ploutz-Snyder RJ, Marshall-Goebel K, Riascos RF, Macias BR.
Intracranial effects of microgravity: A prospective longitudinal MRI study.
Radiology. 2020 Apr 14. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: B.R. Macias
Note: ISS results. For an editorial about this article, see ‘Other papers of interest’ #3. This article may be obtained online without charge.
Journal Impact Factor: 7.608
Funding: This was a directed study funded by the NASA Human Research Program.
2
Turner RT, Philbrick KA, Wong CP, Gamboa AR, Branscum AJ, Iwaniec UT.
Effects of propranolol on bone, white adipose tissue, and bone marrow adipose tissue in mice housed at room temperature or thermoneutral temperature.
Front Endocrinol (Lausanne). 2020 Mar 17;11:117.
https://www.ncbi.nlm.nih.gov/
PI: R.T. Turner
Note: This article may be obtained online without charge.
Journal Impact Factor: 7.852
Funding: “This work was supported by NIH (AR 054609), USDA (38420-17804), and NASA (80NSSC19K0430).”
3
Pollard AK, Gaffney CJ, Deane CS, Balsamo M, Cooke M, Ellwood RA, Hewitt JE, Mierzwa BE, Mariani A, Vanapalli SA, Etheridge T, Szewczyk NJ.
Molecular muscle experiment: Hardware and operational lessons for future astrobiology space experiments.
Astrobiology. 2020 Apr 8. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: S.A. Vanapalli
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.768
Funding: “This work was supported by the BBSRC (Grant Nos. BB/N015894/1, BB/P025781/1); the UK Space Agency and the STFC (Grant No. ST/R005737/1); and ESA (designations Molecular Muscle Experiment and ESA-14-ISLRA_Prop-0029). J.E.H. and S.A.V. were supported by the National Aeronautics and Space Administration (NASA) (NNX15AL16G to S.A.V.). Some strains were provided by the CGC, which is funded by NIH Office of Research Infrastructure Programs (P40 OD010440).”
4
Nangle SN, Wolfson MY, Hartsough L, Ma NJ, Mason CE, Merighi M, Nathan V, Silver PA, Simon M, Swett J, Thompson DB, Ziesack M.
The case for biotech on Mars.
Nat Biotechnol. 2020 Apr;38(4):401-7.
https://www.ncbi.nlm.nih.gov/
PI: C.E. Mason
Journal Impact Factor: 31.864
Funding: “S.N.N. thanks the Harvard Climate Change Solutions Fund for support. C.E.M. thanks WorldQuant, NASA (NNX14AH50G, NNX17AB26G) and TRISH (NNX16AO69A:0107, NNX16AO69A:0061).”
______________________________
Other papers of interest:
1
Lei X, Cao Y, Ma B, Zhang Y, Ning L, Qian J, Zhang L, Qu Y, Zhang T, Li D, Chen Q, Shi J, Zhang X, Ma CW, Zhang Y, Duan E.
Development of mouse preimplantation embryos in space.
Natl Sci Rev. 2020 Apr 11. [Article in Press]
https://academic.oup.com/nsr/
Note: Chinese satellite SJ-10 results. This article may be obtained online without charge.
2
Chen ZY, Jiang N, Guo S, Li BB, Yang JQ, Chai SB, Yan HF, Sun PM, Zhang T, Sun HW, Yang HM, Zhou JL, Cui Y.
Effect of simulated microgravity on metabolism of HGC-27 gastric cancer cells.
Oncol Lett. 2020 May;19(5):3439-50. Epub 2020 Mar 10.
https://www.ncbi.nlm.nih.gov/
Note: A Rotary Cell Culture System bioreactor was used. This article may be obtained online without charge.
3
Lev MH.
The long-term effects of spaceflight on human brain physiology.
Radiology. 2020 Apr 14. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The author comments on NASA #1. This article may be obtained online without charge.
4
Mayer D, Guerrero F, Goanvec C, Hetzel L, Linders J, Ljubkovic M, Kreczy A, Mayer C, Kirsch M, Ferenz KB.
Prevention of decompression sickness by novel artificial oxygen carriers.
Med Sci Sports Exerc. 2020 Apr 1. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
5
Meng WT, Qing L, Li CZ, Zhang K, Yi HJ, Zhao XP, Xu WG.
Ulinastatin: A potential alternative to glucocorticoid in the treatment of severe decompression sickness.
Front Physiol. 2020 Mar 26;11:273.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
6
Kawao N, Morita H, Iemura S, Ishida M, Kaji H.
Roles of Dkk2 in the linkage from muscle to bone during mechanical unloading in mice.
Int J Mol Sci. 2020 Apr 6;21(7):E2547.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading and centrifugation were used. This article may be obtained online without charge.
7
White DA, Harkin KR, Roush JK, Renberg WC, Biller D.
Fortetropin inhibits disuse muscle atrophy in dogs after tibial plateau leveling osteotomy.
PLoS One. 2020 Apr 9;15(4):e0231306.
https://www.ncbi.nlm.nih.gov/
Note: Animals used were 100 “client-owned dogs presenting for surgical correction of cranial cruciate ligament rupture by tibial plateau leveling osteotomy.” This article may be obtained online without charge.
8
Alkhalil A, Clifford JL, Ball R, Day A, Chan R, Carney BC, Miller SA, Campbell R, Kumar R, Gautam A, Hammamieh R, Moffatt LT, Shupp JW.
Blood RNA integrity is a direct and simple reporter of radiation exposure and prognosis: A pilot study.
Radiat Res. 2020 Apr 13. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
9
Szymonowicz K, Krysztofiak A, Linden JV, Kern A, Deycmar S, Oeck S, Squire A, Koska B, Hlouschek J, Vullings M, Neander C, Siveke JT, Matschke J, Pruschy M, Timmermann B, Jendrossek V.
Proton irradiation increases the necessity for homologous recombination repair along with the indispensability of non-homologous end joining.
Cells. 2020 Apr 5;9(4):E889.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
10
Wei W, Bai H, Feng X, Hua J, Long K, He J, Zhang Y, Ding N, Wang J, Zhou H.
Serum proteins as new biomarkers for whole-body exposure to high- and low-LET ionizing radiation.
Dose Response. 2020 Jan-Mar;18(1):
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
11
Kramer A, Kummel J, Dreiner M, Willwacher S, Frett T, Niehoff A, Gruber M.
Adaptability of a jump movement pattern to a non-constant force field elicited via centrifugation.
PLoS One. 2020 Apr 8;15(4):e0230854.
https://www.ncbi.nlm.nih.gov/
Note: A short arm human centrifuge was used. This article may be obtained online without charge.
12
Bao Y, Bassham DC.
COST1 balances plant growth and stress tolerance via attenuation of autophagy.
Autophagy. 2020 Apr 9. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
13
Caplin NM, Halliday A, Willey NJ.
Developmental, morphological and physiological traits in plants exposed for five generations to chronic low-level ionising radiation.
Front Plant Sci. 2020 Apr 15;11:389.
https://www.frontiersin.org/
Note: This article may be obtained online without charge.
14
Guastello SJ, Futch W, Mirabito L.
Cognitive workload and fatigue dynamics in a chaotic forecasting task.
Nonlinear Dynamics Psychol Life Sci. 2020 Apr;24(2):179-213.
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used.
