Status Report

NASA Spaceline Current Awareness List #871 25 October 2019 (Space Life Science Research Results)

By SpaceRef Editor
October 25, 2019
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SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

 

Papers deriving from NASA support:

 

1

Roberts DR, Brown TR, Nietert PJ, Eckert MA, Inglesby DC, Bloomberg JJ, George MS, Asemani D.

Prolonged microgravity affects human brain structure and function.

AJNR Am J Neuroradiol. 2019 Oct 17. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31624117

PI: D.R. Roberts

Note: ISS and Shuttle results.

Journal Impact Factor: 3.256

Funding: “This study was funded by a grant from the National Aeronautics and Space Administration (NNX13AJ92G). Dr Nietert’s time on this project was funded, in part, by the National Institutes of Health National Center for Advancing Translational Science (grant No. UL1-TR001450) and the National Institute of General Medical Sciences (grant No. U54-GM104941). Dr Inglesby’s time on this project was funded by a Minorities in STEM Student Scholarship from the South Carolina Space Grant Consortium (grant No. NNX15AL49H).”

 

2

Milgrom SA, Varghese B, Gladish GW, Choi AD, Dong W, Patel ZS, Chung CC, Rao A, Pinnix CC, Gunther JR, Dabaja BS, Lin SH, Hoffman KE, Huff JL, Slagowski J, Abe JI, Iliescu CA, Banchs J, Yusuf SW, Lopez-Mattei JC. 

Coronary artery dose-volume parameters predict risk of calcification after radiation therapy.

J Cardiovasc Imaging. 2019 Oct;27(4):268-79.

https://www.ncbi.nlm.nih.gov/pubmed/31614398

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: No funding cited. J.L. Huff  and Z.S. Patel are affiliated with NASA Johnson Space Center.

 

3

Mishra B, Luderer U.

Reproductive hazards of space travel in women and men.

Nat Rev Endocrinol. 2019 Oct 14. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/31611649

PI: U. Luderer

Journal Impact Factor: 24.646

Funding: No funding cited. PI reports several studies discussed in the review were supported by NASA grant NNX14AC50G.

 

4

Banks S, Landon LB, Dorrian J, Waggoner LB, Centofanti SA, Roma PG, Van Dongen HPA.

Effects of fatigue on teams and their role in 24/7 operations.

Sleep Med Rev. 2019 Sep 28;48:101216.

https://www.ncbi.nlm.nih.gov/pubmed/31630015

Journal Impact Factor: 10.517

Funding: “Manuscript preparation for all authors was supported by University of South Australia, Alliances Development funding. LBL and PGR are supported by KBR’s Human Health and Performance Contract NNJ15HK11B through the National Aeronautics and Space Administration. LBW is supported by Delta Air Lines, Inc. SAC is supported by National Health and Medical Research, Australia project grant APP1099077. HVD is supported by Congressionally Directed Medical Research Program, United States; Delta Air Lines, Inc., United States grant W81XWH-16-1-0319.”

 

5

Connaboy C, LaGoy AD, Johnson CD, Sinnott AM, Eagle SR, Bower JL, Pepping G-J, Simpson RJ, Alfano CA.

Sleep deprivation impairs affordance perception behavior during an action boundary accuracy assessment.

Acta Astronaut. 2020 Jan;166:270-6. Epub 2019 Oct 22.

http://www.sciencedirect.com/science/article/pii/S0094576519313438

PIs: C.A. Alfano, R.J. Simpson

Note: Results are from a 30-day NASA Human Exploration Research Analog (HERA) mission.

Journal Impact Factor: 2.482

Funding: “This work was supported by the National Aeronautics and Space Administration; grant number NNX15AC13G (Principal Investigators: Simpson and Alfano).”

 

6

Seuylemezian A, Ott L, Wolf S, Fragante J, Yip O, Pukall R, Schumann P, Vaishampayan P.

Bacillus glennii sp. nov. and Bacillus saganii sp. nov., isolated from the vehicle assembly building at Kennedy Space Center where the Viking spacecraft were assembled.

Int J Syst Evol Microbiol. 2019 Oct 17. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31622233      

Journal Impact Factor: 2.166

Funding: “This research was funded by the Mars Program Office at JPL.”

_______________________________________________________

 

 

Other papers of interest:

 

1

Dirks ML, Wall BT, Otten B, Cruz AM, Dunlop MV, Barker AR, Stephens FB.

High-fat overfeeding does not exacerbate rapid changes in forearm glucose and fatty acid balance during immobilization.

J Clin Endocrinol Metab. 2019 Oct 14. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31609422

Note: Forearm casting was used to study the effects of immobilization of the arm.

 

2

Rui Q, Dong S, Jiang W, Wang D.

Response of canonical Wnt/β-catenin signaling pathway in the intestine to microgravity stress in Caenorhabditis elegans.

Ecotoxicol Environ Saf. 2019 Dec;186:109782. Epub 2019 Oct 12.

https://www.ncbi.nlm.nih.gov/pubmed/31614302

Note: A Rotary Cell Culture System was used.

 

3

Baek MO, Ahn CB, Cho HJ, Choi JY, Son KH, Yoon MS.

Simulated microgravity inhibits C2C12 myogenesis via phospholipase D2-induced Akt/FOXO1 regulation.

Sci Rep. 2019 Oct 17;9(1):14910.

https://www.ncbi.nlm.nih.gov/pubmed/31624287

Note: A 3D clinostat was used. This article may be obtained online without charge.

 

4

Kwon S, Kim KS.

Qualitative analysis of contribution of intracellular skeletal changes to cellular elasticity.

Cell Mol Life Sci. 2019 Oct 11. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/31605149

 

5

Ahn SJ, Deep K, Turner ME, Ishkov I, Waters A, Hagen SJ, Rice KC.

Characterization of LrgAB as a stationary phase-specific pyruvate uptake system in Streptococcus mutans.

BMC Microbiol. 2019 Oct 12;19(1):223.

https://www.ncbi.nlm.nih.gov/pubmed/31606034

Note: This article may be obtained online without charge.

 

6

Mitchell JH, Levine BD, McGuire DK.

The Dallas Bed Rest and Training Study: Revisited after 50 years.

Circulation. 2019 Oct 15;140(16):1293-5.

https://www.ncbi.nlm.nih.gov/pubmed/31609661

Note: Bed rest study.

 

7

Chavez C, Cruz-Becerra G, Fei J, Kassavetis GA, Kadonaga JT.

The tardigrade damage suppressor protein binds to nucleosomes and protects DNA from hydroxyl radicals.

Elife. 2019 Oct 1;8:e47682.

https://www.ncbi.nlm.nih.gov/pubmed/31571581

Note: This article may be obtained online without charge.

 

8

Jin M, Wang J, Zhang H, Zhou H, Zhao K.

Simulated weightlessness perturbs the intestinal metabolomic profile of rats.

Front Physiol. 2019 Oct 15;10:1279.

https://www.frontiersin.org/articles/10.3389/fphys.2019.01279/full

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

9

Hassan CR, Qin YX, Komatsu DE, Uddin SMZ.

Utilization of finite element analysis for articular cartilage tissue engineering.

Materials (Basel). 2019 Oct 12;12(20):E3331. Review.

https://www.ncbi.nlm.nih.gov/pubmed/31614845

Note: This article may be obtained online without charge.

 

10

Tyganov SA, Mochalova EP, Belova SP, Sharlo KA, Rozhkov SV, Vilchinskaya NA, Paramonova II, Mirzoev TM, Shenkman BS.

Effects of plantar mechanical stimulation on anabolic and catabolic signaling in rat postural muscle under short-term simulated gravitational unloading.

Front Physiol. 2019 Sep 27;10:1252.

https://www.ncbi.nlm.nih.gov/pubmed/31611819

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

11

Dulany K, Hepburn K, Goins A, Allen JB.

In-vitro and in-vivo biocompatibility assessment of free radical scavenging nanocomposite scaffolds for bone tissue regeneration.

J Biomed Mater Res A. 2019 Oct 13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31606924

 

12

Kegelman CD, Coulombe JC, Jordan KM, Horan DJ, Qin L, Robling AG, Ferguson VL, Bellido TM, Boerckel JD.

YAP and TAZ mediate osteocyte perilacunar/canalicular remodeling.

J Bone Miner Res. 2019 Oct 14. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31610061

 

13

Gu J, Norquist A, Brooks C, Repin M, Mukherjee S, Lacombe J, Yang J, Brenner DJ, Amundson S, Zenhausern F.

Development of an integrated fingerstick blood self-collection device for radiation countermeasures.

PLoS One. 2019 Oct 16;14(10):e0222951.

https://www.ncbi.nlm.nih.gov/pubmed/31618210

Note: This article may be obtained online without charge.

 

14

Hunt CR, Pandita TK.

“What’s past is prologue:” Pre-existing epigenetic transcriptional marks may also influence DNA repair pathway choice.

Radiat Res. 2019 Oct 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31634055

 

15

Liu M, Yuan H, Yin J, Wang R, Song J, Hu B, Li J, Qin X.

Effect of hydrogen-rich water on radiation-induced cognitive dysfunction in rats.

Radiat Res. 2019 Oct 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31634054

 

16

Qian J, Scheer F, Hu K, Shea SA.

The circadian system modulates the rate of recovery of systolic blood pressure after exercise in humans.

Sleep. 2019 Oct 16. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31616941

 

17

Stein M, Richards E.

Aerospace, physical effects.

In: StatPearls. Treasure Island (FL): StatPearls Publishing, 2019. 6 p.

https://www.ncbi.nlm.nih.gov/pubmed/31613438

Note: This article may be obtained online without charge.

 

18

Christiaens MER, De Paepe J, Ilgrande C, De Vrieze J, Barys J, Teirlinck P, Meerbergen K, Lievens B, Boon N, Clauwaert P, Vlaeminck SE.

Urine nitrification with a synthetic microbial community.

Syst Appl Microbiol. 2019 Sep 23. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31623889

 

19

Shamsan GA, Odde DJ.

Emerging technologies in mechanotransduction research.

Curr Opin Chem Biol. 2019 Dec;53:125-30. Review. Epub 2019 Oct 13.

https://www.ncbi.nlm.nih.gov/pubmed/31618703

 

20

Emami Z, Chau T.

The effects of visual distractors on cognitive load in a motor imagery brain-computer interface.

Behav Brain Res. 2019 Oct 12. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/31614183

Note: Behav Brain Res. 2019 Oct 12. [Epub ahead of print]

 

21

Legenza L, Nickman NA, Drews FA, Rim M, Tigh J, Kelly MP, Tyler LS.

Assessment of perceived workload in academic health center community pharmacies before and after implementation of a central call center.

Am J Health Syst Pharm. 2019 Oct 15;76(21):1794-805.

https://www.ncbi.nlm.nih.gov/pubmed/31612926

Note: The NASA Task Load Index was used.

 

SpaceRef staff editor.