NASA Spaceline Current Awareness List #865 13 September2019 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Bretl KN, Sherman SO, Dixon JB, Mitchell TR, Clark TK.
A standardized, incremental protocol to increase human tolerance to the cross-coupled illusion.
J Vestib Res. 2019 Aug 24. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: A short-radius centrifuge was used.
Journal Impact Factor: 2.774
Funding: “This work was supported by a NASA Space Technology Research Fellowship.”
2
Garschagen LS, Mancinelli RL, Moeller R.
Introducing Vibrio natriegens as a microbial model organism for microgravity research.
Astrobiology. 2019 Sep 5. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: R.L. Mancinelli
Note: A 2-D clinostat was used.
Journal Impact Factor: 3.768
Funding: “L.S.G. and R.M. were supported by DLR grant DLR-FuE-Projekt ISS LIFE (Programm RF-FuW, Teilprogramm 475) and R.L.M. by NASA Grant 80NSSC18K0751 to the Bay Area Environmental Research Institute.”
3
Carnell LS, Homer M, Hoots K, Meeks H, Prasanna PGS, Rios C, Simonsen LC, Taliaferro LP, Wathen LK.
Medical countermeasures for radiation induced health effects: Report of an Interagency Panel Session held at the NASA Human Research Program Investigator’s Workshop, January 26, 2017.
Int J Radiat Biol. 2019 Sep 6. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 2.266
Funding: No funding cited. L.S. Carnell and L.C. Simonsen are affiliated with NASA Langley Research Center.
4
Hada M, Saganti PB, Cucinotta FA.
Nitric oxide is involved in heavy ion-induced non-targeted effects in human fibroblasts.
Int J Mol Sci. 2019 Sep 4;20(18):E4327.
https://www.ncbi.nlm.nih.gov/
PIs: F.A. Cucinotta, M. Hada
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.183
Funding: “This research was funded by the NASA Human Research Program Space Radiation Program and DoE Low Dose program (DE-AI02-10ER64969) (F.A.C.) and TAMU Chancellor’s Research Initiative, Texas A&M University (P.B.S.).”
5
Nowak ES, Reyes DP, Bryant BJ, Cap AP, Kerstman EL, Antonsen EL.
Blood transfusion for deep space exploration.
Transfusion. 2019 Sep 6. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 3.111
Funding: No funding cited. D.P. Reyes, E.L. Kerstman, and E.L. Antonsen are affiliated with NASA Johnson Space Center.
6
Zhu B, Kwon S, Rasmussen JC, Litorja M, Sevick-Muraca EM.
Comparison of NIR versus SWIR fluorescence image device performance using working standards calibrated with SI units.
IEEE Trans Med Imaging. 2019 Aug 27. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: E.M. Sevick-Muraca
Journal Impact Factor: 7.816
Funding: “This work was supported in parts by the Translational Research Institute through NASA Cooperative Agreement NX16AO69A.”
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Other papers of interest:
1
Mora M, Wink L, Kögler I, Mahnert A, Rettberg P, Schwendner P, Demets R, Cockell C, Alekhova T, Klingl A, Krause R, Zolotariof A, Alexandrova A, Moissl-Eichinger C.
Space Station conditions are selective but do not alter microbial characteristics relevant to human health.
Nat Commun. 2019 Sep 5;10(1):3990.
https://www.ncbi.nlm.nih.gov/
Note: ISS results. This article may be obtained online without charge.
2
Chatani M, Mitsuhashi A, Dodo Y, Sakai N, Takami M.
Hypergravity induces vertebrae and otolith deformation in medaka fish.
Biol Sci Space. 2019;33:12-7.
https://www.jstage.jst.go.jp/
Note: Centrifugation was used. This article may be obtained online without charge.
3
Chen YC, Aui SP, Lai YS, Chang KT.
Adult stem cells in hibernation: Future perspectives of space travel.
Int J Stem Cells. 2019 Aug 31. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
4
Malaeva VV, Pochekutova IA, Korenbaum VI, Kostiv AE, Shin SN, Safronova MA, Katuntsev VP, Baranov VM.
Estimation of short- and long-term postural effects used for lunar gravity simulation on human tracheal forced expiratory noise time.
Hum Physiol. 2019 Jul 1;45(4):412-20.
https://link.springer.com/
Note: Head-down tilt bed rest study.
5
Markina EA, Zhuravleva OA, Kuzichkin DS, Mukhamedieva LN, Markin AA, Vostrikova LV, Zabolotskaya IV, Loginov VI.
Dynamics of lipid metabolism in volunteers during short-term isolation in a hermetic chamber.
Hum Physiol. 2019 Jul 1;45(4):421-5.
https://link.springer.com/
Note: The 17-day study was conducted in a hermetic chamber.
6
Sapp RM, Evans WS, Eagan LE, Chesney CA, Zietowski EM, Prior SJ, Ranadive SM, Hagberg JM.
The effects of moderate and high intensity exercise on circulating markers of endothelial integrity and activation in young, healthy men.
J Appl Physiol (1985). 2019 Sep 5. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
7
Ding J, Li F, Cong Y, Miao J, Wu D, Liu B, Wang L.
Trichostatin A inhibits skeletal muscle atrophy induced by cigarette smoke exposure in mice.
Life Sci. 2019 Oct 15;235:116800. Epub 2019 Aug 28.
https://www.ncbi.nlm.nih.gov/
8
Tomiga Y, Ito A, Sudo M, Ando S, Eshima H, Sakai K, Nakashima S, Uehara Y, Tanaka H, Soejima H, Higaki Y.
One-week, but not 12-hours, cast immobilization alters promotor DNA methylation patterns in the nNOS gene in mouse skeletal muscle.
J Physiol. 2019 Sep 6. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Cast immobilization was used.
9
Trevino MB, Zhang X, Standley RA, Wang M, Han X, Reis FCG, Periasamy M, Yu G, Kelly DP, Goodpaster BH, Vega RB, Coen PM.
Loss of mitochondrial energetics is associated with poor recovery of muscle function but not mass following disuse atrophy.
Am J Physiol Endocrinol Metab. 2019 Sep 3. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Bed rest study.
10
Winnard A, Scott J, Waters N, Vance M, Caplan N.
Effect of time on human muscle outcomes during simulated microgravity exposure without countermeasures—Systematic review.
Front Physiol. 2019 Aug 16;10:1046. Review.
https://www.ncbi.nlm.nih.gov/
Note: Bed rest studies are reviewed. This article may be obtained online without charge.
11
Karthik K, Vasumathy R, Pandey BN, Thayalan K, Venkatachalam P.
Primary and secondary bystander effect and genomic instability in cells exposed to high and low linear energy transfer radiations.
Int J Radiat Biol. 2019 Sep 5. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
12
Khosravi-Hashemi N, Forbes PA, Dakin CJ, Blouin JS.
Virtual signals of head rotation induce gravity-dependent inferences of linear acceleration.
J Physiol. 2019 Sep 4. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
13
Wang H, Xu Y, Hong L, Zhang X, Wang X, Zhang J, Ding Z, Meng Z, Wang ZY, Long R, Yang Q, Kong F, Han L, Zhou C.
HEADLESS regulates auxin response and compound leaf morphogenesis in Medicago truncatula.
Front Plant Sci. 2019 Sep 3;10:1024.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
14
Szocik K, Norman Z, Reiss MJ.
Ethical challenges in human space missions: A space refuge, scientific value, and human gene editing for space.
Sci Eng Ethics. 2019 Sep 3. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
15
Garbin N, Mamunes AP, Sohn D, Hawkins RW, Valdastri P, Obstein KL.
Evaluation of a novel low-cost disposable endoscope for visual assessment of the esophagus and stomach in an ex-vivo phantom model.
Endosc Int Open. 2019 Sep;7(9):E1175-E1183.
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used. This article may be obtained online without charge.
16
Lau E, Alkhamesi NA, Schlachta CM.
Impact of robotic assistance on mental workload and cognitive performance of surgical trainees performing a complex minimally invasive suturing task.
Surg Endosc. 2019 Sep 3. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used.
