NASA Spaceline Current Awareness List #858 19 July 2019 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website athttps://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Voorhies AA, Ott MC, Mehta S, Pierson DL, Crucian BE, Feiveson A, Oubre CM, Torralba M, Moncera K, Zhang Y, Zurek E, Lorenzi HA.
Study of the impact of long-duration space missions at the International Space Station on the astronaut microbiome.
Sci Rep. 2019 Jul 9;9(1):9911.
https://www.ncbi.nlm.nih.gov/
PI: H.A. Lorenzi
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: 4.011
Funding: “This work was supported by the NASA Human Research Program under grant number NNX12AB02G.”
2
Grover K, Hu M, Lin L, Muir J, Qin YX.
Functional disuse initiates medullary endosteal micro-architectural impairment in cortical bone characterized by nanoindentation.
J Bone Miner Metab. 2019 Jul 10. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: Y.X. Qin
Note: Hindlimb unloading study.
Journal Impact Factor: 2.310
Funding: “This work is kindly supported by the National Institute of Health (R01 AR52379 and R01AR61821), the US Army Medical Research and Materiel Command, The National Space Biomedical Research Institute through NASA contract NCC 9-58.”
3
Plante I, Ponomarev A, Patel Z, Slaba T, Hada M.
RITCARD: Radiation-induced tracks, chromosome aberrations, repair and damage.
Radiat Res. 2019 Jul 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: M. Hada
Journal Impact Factor: 2.530
Funding: “This work was supported by NASA Space Radiation Program (grant no. NNX16AR97G to MH), NASA Human Health and Performance Contract (HHPC; no. NNJ15HK11B), and TAMU Chancellor’s Research Initiative, Texas A&M University.”
4
Whitman K, Norbury JW, Lee K, Slaba TC, Badavi FF.
Comparison of space radiation GCR models to AMS heavy ion data.
Life Sci Space Res. 2019 Jul 12. [Article in Press]
http://www.sciencedirect.com/
PI: J.W. Norbury
Journal Impact Factor: 2.066
Funding: “This work was supported by the Advanced Exploration Systems (AES) Division under the Human Exploration and Operations Mission Directorate of NASA.”
5
Ronca AE, Moyer EL, Talyansky Y, Lowe M, Padmanabhan S, Choi S, Gong C, Cadena SM, Stodieck L, Globus RK.
Author Correction: Behavior of mice aboard the International Space Station.
Sci Rep. 2019 Jul 9;9(1):10154.
https://www.ncbi.nlm.nih.gov/
Note: Corrections were made to an author address and, in the abstract, the number of days after launch that mice began circling behavior. The original article was: Ronca AE, Moyer EL, Talyansky Y, Lowe M, Padmanabhan S, Choi S, Gong C, Cadena SM, Stodieck L, Globus RK. Behavior of mice aboard the International Space Station. Sci Rep. 2019 Apr 11;9(1):4717. https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 4.011
Funding: From the original article: “Funding was provided by the NASA Ames Research Center Space Biology Program, Rodent Research Project, and Center Directors Fund.”
6
Scheuring RA, Schmid JF, Polk JD.
Environmental extremes: Space.
In: O’Connor FG, Schoomaker EB, Smith DC, eds. Fundamentals of Military Medicine. Textbooks of Military Medicine. Ft. Sam Houston, TX: Borden Institute, 2019. p. 347-62.
Journal Impact Factor: Not applicable to this publication
Funding: No funding cited. J.D. Polk is affiliated with NASA Headquarters.
7
International Space Station Benefits for Humanity.
Houston, TX: NASA Johnson Space Center, 2019. 236 p. NP-2018-06-013-JSC.
https://www.nasa.gov/mission_
Note: The book is a collaborative work by the members of the International Space Station Program Science Forum: National Aeronautics and Space Administration, Canadian Space Agency, European Space Agency, Japan Aerospace Exploration Agency, Russian Federal Space Agency, and Italian Space Agency. From the Executive Summary: “The third edition of the International Space Station Benefits for Humanity is a compilation of benefits being realized from International Space Station (ISS) activities in the areas of human health, Earth observations and disaster response, innovative technology, global education, and economic development of space. This revision also includes new assessments of economic value and scientific value in more detail than the second edition. The third edition contains updated statistics on the impacts of the benefits as well as new benefits that have developed since the previous publication. International Space Station Benefits for Humanity is a product of the ISS Program Science Forum (PSF), which consists of senior science representatives across the ISS international partnership.” This publication may be obtained online without charge.
Journal Impact Factor: Not applicable to this publication
Funding: From the acknowledgements: “A Product of the International Space Station Program Science Forum.”
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Other papers of interest:
1
Tseng WS, Chien WC, Chung CH, Chou YC, Tzeng NS.
Risk of sleep disorders in patients with decompression sickness: A nationwide, population-based study in Taiwan.
Psychiatr Danub. 2019 Jun;31(2):172-81.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
2
Jalal N, Gracies JM, Zidi M.
Mechanical and microstructural changes of skeletal muscle following immobilization and/or stroke.
Biomech Model Mechanobiol. 2019 Jul 6. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Rat forelimb immobilization was used.
3
Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, Gerber KK, Mattheis L, Chen W, Tu H, Bouxsein ML, Griffin PR, Baron R, Rosen CJ, Bonewald LF, Spiegelman BM.
Irisin mediates effects on bone and fat via αV integrin receptors [Erratum].
Cell. 2019 Jul 11;178(2):507-8.
https://www.ncbi.nlm.nih.gov/
Note: From the authors: “Our paper identified αV integrins as the cellular receptors for irisin, acting in osteocytes and adipocytes. During figure preparation, we inadvertently duplicated the β-actin western blot image from Figure S6A in Figure S4C. We have now corrected Figure S4C with the β-actin control that was executed with the experiment shown. In addition, in Figure S4D, the protein integrin α was mistakenly labeled as “integrin αV.” This label has been amended. The corrected figure appears below and in the paper online. We apologize for any confusion this duplication may have caused.” The original article was: Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, Gerber KK, Mattheis L, Chen W, Tu H, Bouxsein ML, Griffin PR, Baron R, Rosen CJ, Bonewald LF, Spiegelman BM. Irisin mediates effects on bone and fat via ɑV integrin receptors. Cell. 2018 Dec 13;175(7):1756-68.e17. https://www.ncbi.nlm.nih.gov/
4
Kirby TJ.
Mechanosensitive pathways controlling translation regulatory processes in skeletal muscle and implications for adaptation.
J Appl Physiol (1985). 2019 Jul 11. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
5
Sun W, Chi S, Li Y, Ling S, Tan Y, Xu Y, Jiang F, Li J, Liu C, Zhong G, Cao D, Jin X, Zhao D, Gao X, Liu Z, Xiao B, Li Y.
The mechanosensitive Piezo1 channel is required for bone formation.
Elife. 2019 Jul 10;8:e47454.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study. This article may be obtained online without charge.
6
Yang PF, Nie XT, Wang Z, Al-Qudsy LHH, Ren L, Xu HY, Rittweger J, Shang P.
Disuse impairs the mechanical competence of bone by regulating the characterizations of mineralized collagen fibrils in cortical bone.
Front Physiol. 2019 Jun 21;10:775.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study. This article may be obtained online without charge.
7
Li Q, Li K, Zhang S, Zhou Y, Hong J, Zhou X, Li Z, Wu B, Wu G, Meng R.
The effect of ionizing radiation on the subcellular localization and kinase activity of protein kinase CK2 in human non-small cell lung cancer cells.
Int J Radiat Biol. 2019 Jul 10. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
8
Liu R, Zhao T, Swat MH, Reynoso FJ, Higley KA.
Development of computational model for cell dose and DNA damage quantification of multicellular system.
Int J Radiat Biol. 2019 Jul 10. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
9
Razskazovskiy Y, Tegomoh M, Roginskaya M.
Association with polyamines and polypeptides increases the relative yield of 2-deoxyribonolactone lesions in radiation-damaged DNA.
Radiat Res. 2019 Jul 12. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
10
Royba E, Repin M, Pampou S, Karan C, Brenner DJ, Garty G.
RABiT-II-DCA: A fully-automated dicentric chromosome assay in multiwell plates.
Radiat Res. 2019 Jul 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
11
Saif-Elnasr M, Abdel Fattah SM, Swailam HM.
Treatment of hepatotoxicity induced by γ-radiation using platelet rich plasma and/or low molecular weight chitosan in experimental rats.
Int J Radiat Biol. 2019 Jul 10. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
12
Song CH, Joo HM, Han SH, Kim JI, Nam SY, Kim JY.
Low-dose ionizing radiation attenuates mast cell migration through suppression of monocyte chemoattractant protein-1 (MCP-1) expression by Nr4a2.
Int J Radiat Biol. 2019 Jul 9. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
13
Yushkova E.
Effects of ionizing radiation at Drosophila melanogaster with differently active hobo transposons.
Int J Radiat Biol. 2019 Jul 9. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
14
Dias RD, Zenati MA, Stevens R, Gabany JM, Yule SJ.
Physiological synchronization and entropy as measures of team cognitive load.
J Biomed Inform. 2019 Jul 8. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
15
Ma Q, Sandal GM, Wu R, Xiong J, Li Y, Xu Z, He L, Liu Y.
Personal value diversity in confinement and isolation: Pilot study results from the 180-day CELSS integration experiment.
Acta Astronaut. 2019 Jul 12. [Article in Press]
http://www.sciencedirect.com/
Note: Results are reported from a 180-day study in the Chinese Controlled Ecological Life Support System (CELSS).
16
Martins-Lopes V, Bellmunt A, Greguske EA, Maroto AF, Boadas-Vaello P, Llorens J.
Quantitative assessment of anti-gravity reflexes to evaluate vestibular dysfunction in rats.
J Assoc Res Otolaryngol. 2019 Jul 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Vestibular dysfunction was elicited by acute or sub-chronic exposure to 3,3′-iminodipropionitrile (IDPN).
17
Sayyid ZN, Wang T, Chen L, Jones SM, Cheng AG.
Atoh1 directs regeneration and functional recovery of the mature mouse vestibular system.
Cell Rep. 2019 Jul 9;28(2):312-24.e4.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
18
Lewkowicz R.
A centrifuge-based flight simulator: Optimization of a baseline acceleration profile based on the motion sickness incidence.
Acta Astronaut. 2019 Nov;164:23-33. Epub 2019 Jul 12.
http://www.sciencedirect.com/
Note: A centrifuge was used.
19
Rakici SY, Tumkaya L, Celebi Edirvanli O, Yazici U, Dursun E, Arpa M, Mercantepe T.
Radioprotective effect of endogenous melatonin secretion associated with the circadian rhythm in irradiated rats.
Int J Radiat Biol. 2019 Jul 9. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
20
Spitschan M, Stefani O, Blattner P, Gronfier C, Lockley SW, Lucas RJ.
How to report light exposure in human chronobiology and sleep research experiments.
Clocks Sleep. 2019 Jul 1;1(3):280-9.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge beginning September 1, 2019.
21
Ogura T, Goeschl C, Filiault D, Mirea M, Slovak R, Wolhrab B, Satbhai SB, Busch W.
Root system depth in Arabidopsis is shaped by EXOCYST70A3 via the dynamic modulation of auxin transport.
Cell. 2019 Jul 11;178(2):400-12.e16.
https://www.ncbi.nlm.nih.gov/
22
Tada Y.
The HKT transporter gene from Arabidopsis, AtHKT1;1, is dominantly expressed in shoot vascular tissue and root tips and is mild salt stress-responsive.
Plants (Basel). 2019 Jul 4;8(7):E204.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
23
Wang M, Dong C, Gao W.
Evaluation of the growth, photosynthetic characteristics, antioxidant capacity, biomass yield and quality of tomato using aeroponics, hydroponics and porous tube-vermiculite systems in bio-regenerative life support systems.
Life Sci Space Res. 2019 Aug;22:68-75.
http://www.sciencedirect.com/
24
Melo HM, Hoeller AA, Walz R, Takase E.
Resting cardiac vagal tone is associated with long-term frustration level of mental workload: Ultra-short term recording reliability.
Appl Psychophysiol Biofeedback. 2019 Jul 8. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used.
