Status Report

NASA Spaceline Current Awareness List #856 5 July 2019 (Space Life Science Research Results)

By SpaceRef Editor
July 5, 2019
Filed under , , ,

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,



Papers deriving from NASA support:



Geier ET, Theilmann RJ, Darquenne C, Prisk GK, Sá RC.

Quantitative mapping of specific ventilation in the human lung using proton magnetic resonance imaging and oxygen as a contrast agent.

J Vis Exp. 2019 Jun 5(148):e59579.

PI: R.C. Sá, NSBRI Postdoctoral Fellowship Program

Journal Impact Factor: 1.184

Funding: “This work was supported by the National Heart, Lung and Blood Institute (NHLBI) (grants R01 HL-080203, R01 HL-081171, R01 HL-104118 and R01-HL119263) and the National Space Biomedical Research Institute (National Aeronautics and Space Administration grant NCC 9-58). E.T. Geier was supported by NHLBI grant F30 HL127980.”



Kumar S, Suman S, Fornace AJ, Datta K.

Intestinal stem cells acquire premature senescence and senescence-associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice.

Aging (Albany NY). 2019 Jun 25;11(12):4145-58.

PIs: K. Datta; A.J. Fornace/K. Datta/NSCOR

Note: This article may be obtained online without charge.

Journal Impact Factor: 5.179

Funding: “This study is funded through NASA Grant# NNX13AD58G and NNX15AI21G.”



Burke CS, Georganta E, Marlow S.

A bottom up perspective to understanding the dynamics of team roles in mission critical teams.

Front Psychol. 2019 Jun 11;10:1322.

PI: E. Salas

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.089

Funding: “This work was supported by funding from the National Aeronautics and Space Administration (Grant NNX16AB08G).”




Other papers of interest:



Gulimova V, Proshchina A, Kharlamova A, Krivova Y, Barabanov V, Berdiev R, Asadchikov V, Buzmakov A, Zolotov D, Saveliev S.

Reptiles in space missions: Results and perspectives.

Int J Mol Sci. 2019 Jun 20;20(12):E3019.

Note: Results from Foton-M2, Foton-M3, Foton-M4, and Bion-M1 are discussed. This article may be obtained online without charge.



Kinney L, O’Hare D.

Responding to an unexpected in-flight event: Physiological arousal, information processing, and performance.

Hum Factors. 2019 Jun 25. [Epub ahead of print]



Wang Y, Zhao W, Shi J, Wang J, Hao J, Pang X, Huang X, Chen X, Li Y, Jin R, Ge Q.

Intestinal microbiota contributes to altered glucose metabolism in simulated microgravity mouse model.

FASEB J. 2019 Jun 25. [Epub ahead of print]

Note: Hindlimb unloading study.



Han B, Zhang Y, Li H, Wei S, Li R, Zhang X. 

[Research of simulated microgravity regulate MC3T3-E1 cells differentiation through the nuclear factor-κB signaling pathway].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2019 Jun 25;36(3):421-7. Chinese.

Note: The method of microgravity simulation is not identified in the English abstract.



Ratushnyy A, Yakubets D, Andreeva E, Buravkova L.

Simulated microgravity modulates the mesenchymal stromal cell response to inflammatory stimulation.

Sci Rep. 2019 Jun 26;9(1):9279.

Note: A random positioning machine was used. This article may be obtained online without charge.



Rindom E, Kristensen AM, Overgaard K, Vissing K, de Paoli FV.

Activation of mTORC1 signaling in rat skeletal muscle is independent of the EC-coupling sequence but dependent on tension per se in a dose-response relationship.

Acta Physiol (Oxf). 2019 Jun 24. [Epub ahead of print]



Mattazio RR, Noritomi PY, Silveira ZC.

An in silico model for the prediction of changes in mineral density in cortical bone remodeling.

J Biomech Eng. 2019 Jun 24. [Epub ahead of print]



Qu H, Yi J, Gao X, Zhao H, Wang Z.

Anti-disuse osteoporosis activity of a complex of calcium-binding peptide from Auricularia auricula protein hydrolysates.

J Food Sci. 2019 Jun 25. [Epub ahead of print]

Note: Hindlimb unloading study.



Lee CL, Daniel AR, Holbrook M, Brownstein J, Da Silva Campos L, Hasapis S, Ma Y, Borst L, Badea CT, Kirsch DG.

Sensitization of vascular endothelial cells to ionizing radiation promotes the development of delayed intestinal injury in mice.

Radiat Res. 2019 Jul 2. [Epub ahead of print]



Liu X, Zhou Y, Wang S, Guan H, Hu S, Huang R, Zhou P.

Impact of low-dose ionising radiation on the composition of the gut microbiota of mice.

Toxicol Sci. 2019 Jun 24. [Epub ahead of print]



Klotz IN, Gvozdik TE, Oganesyan AO, Karal-Ogly DD, Demenkova NP, Mukhametzyanova EI, Gvaramiya IA, Danilova IG, Agrba VZ, Lapin BA.

Water immersion as a model of hypogravity.

Bull Exp Biol Med. 2019 Jun;167(2):284-6.

Note: Water immersion was used with rhesus macaques.



Beylergil SB, Karmali F, Wang W, Bermúdez Rey MC, Merfeld DM.

Vestibular roll tilt thresholds partially mediate age-related effects on balance.

Prog Brain Res. 2019;248:249-67.



Clark TK, Newman MC, Karmali F, Oman CM, Merfeld DM.

Mathematical models for dynamic, multisensory spatial orientation perception.

Prog Brain Res. 2019;248:65-90. Review.



King S, Benoit C, Bandealy N, Karmali F.

The influence of target distance on perceptual self-motion thresholds and the vestibulo-ocular reflex during interaural translation.

Prog Brain Res. 2019;248:197-208.

Note: A six degree of freedom motion platform was used.



Laurens J, Angelaki DE.

A model-based reassessment of the three-dimensional tuning of head direction cells in rats.

J Neurophysiol. 2019 Jun 26. [Epub ahead of print]



Sufrinko AM, Kegel NE, Mucha A, Collins MW, Kontos AP.

History of high motion sickness susceptibility predicts vestibular dysfunction following sport/recreation-related concussion.

Clin J Sport Med. 2019 Jul;29(4):318-23.



Roberts SSH, Teo WP, Aisbett B, Warmington SA.

Extended sleep maintains endurance performance better than normal or restricted sleep.

Med Sci Sports Exerc. 2019 Jun 25. [Epub ahead of print]



Argueso CT, Assmann SM, Birnbaum KD, Chen S, Dinneny JR, Doherty CJ, Eveland AL, Friesner J, Greenlee VR, Law JA, Marshall-Colón A, Mason GA, O’Lexy R, Peck SC, Schmitz RJ, Song L, Stern D, Varagona MJ, Walley JW, Williams CM. 

Directions for research and training in plant omics: Big questions and big data.

Plant Direct. 2019 Apr;3(4):e00133.

Note: From the abstract: “In this white paper, we provide a summary of the discussions and insights arising from the second ART-21 [“Arabidopsis Research and Training for the 21st Century”] workshop. The second workshop focused on experimental aspects of omics data acquisition and analysis and involved a broad spectrum of participants from academics and industry, ranging from graduate students through post-doctorates, early career and established investigators.” This article may be obtained online without charge.



Fruleux A, Verger S, Boudaoud A.

Feeling stressed or strained? A biophysical model for cell wall mechanosensing in plants.

Front Plant Sci. 2019 Jun 12;10:757.

Note: This article may be obtained online without charge.



Lee JS, Wilson ME, Richardson RA, Haswell ES.

Genetic and physical interactions between the organellar mechanosensitive ion channel homologs MSL1, MSL2, and MSL3 reveal a role for inter-organellar communication in plant development.

Plant Direct. 2019 Mar;3(3):e00124.

Note: This article may be obtained online without charge.



Marboe I.

Agreement on the Rescue and Return of Astronauts and Objects Launched into Outer Space.

In: Oxford Research Encyclopedia, Planetary Science. Oxford: Oxford University Press, 2019. 26 p.

Note: The author examines implications of space tourism and suborbital flights on provisions set forth in the Agreement on the Rescue and Return of Astronauts and Objects Launched into Outer Space of 1968. This article may be obtained online without charge.



Head J, Tenan MS, Tweedell AJ, Wilson KM, Helton WS.

Response complexity reduces errors on a response inhibition task.

Hum Factors. 2019 Jun 25. [Epub ahead of print]

Note: The NASA Task Load Index was used.

SpaceRef staff editor.