Status Report

NASA Spaceline Current Awareness List #848 10 May 2019 (Space Life Science Research Results)

By SpaceRef Editor
May 10, 2019
Filed under , , ,

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,


Papers deriving from NASA support:



Thiel CS, Tauber S, Seebacher C, Schropp M, Uhl R, Lauber B, Polzer J, Neelam S, Zhang Y, Ullrich O.

Real-time 3D high-resolution microscopy of human cells on the International Space Station.

Int J Mol Sci. 2019 Apr 25;20(8):E2033.

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 3.687

Funding: “This research was funded by the DLR Space Administration on behalf of the Federal Ministry for Economic Affairs and Energy (BMWi), grant no. 50WB1519.” Y. Zhang is affiliated with NASA Kennedy Space Center.



Fischer U, Mosier KL.

Teamwork in spaceflight operations.

In: Ward P, Schraagen JM, Gore J, Roth EM, eds. The Oxford Handbook of Expertise. New York: Oxford University Press, 2019.

PI: U. Fischer

Journal Impact Factor: Not applicable to this publication

Funding: The PI reports funding under NASA grant NNX16AM16G.



Larson L, Wojcik H, Gokhman I, DeChurch L, Bell S, Contractor N.

Team performance in space crews: Houston, we have a teamwork problem.

Acta Astronaut. 2019 May 3. [Article in Press]

PIs: N. Contractor, L. DeChurch

Note: The study was conducted in NASA’s Human Exploration Research Analog (HERA) facility.

Journal Impact Factor: 1.536

Funding: “This research is based upon work supported by NASA under awards NNX15AM32G (Project CREWS), 80NSSC18K0276 (Project CREST), and 80NSSC18K0221 (Project SCALE). Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Aeronautics and Space Administration. We thank Gabriel Plummer, Ashley Niler, and Alexa Harris for their assistance with this research.”



Jimenez M, Langer R, Traverso G.

Microbial therapeutics: New opportunities for drug delivery.

J Exp Med. 2019 May 6;216(5):1005-9.

PI: R. Langer

Note: This article may be obtained online without charge.

Journal Impact Factor: 10.790

Funding: “This work was supported by the Translational Research Institute for Space Health through Cooperative Agreement NNX16AO69A.”




Other papers of interest:



Tominari T, Ichimaru R, Taniguchi K, Yumoto A, Shirakawa M, Matsumoto C, Watanabe K, Hirata M, Itoh Y, Shiba D, Miyaura C, Inada M.

Hypergravity and microgravity exhibited reversal effects on the bone and muscle mass in mice.

Sci Rep. 2019 Apr 29;9(1):6614.

Note: ISS results. Centrifugation was used for hypergravity experiments. This article may be obtained online without charge.



Khoshvaghti A.

Vitamin D in space.

In: Fads and Facts about Vitamin D [Working Title]. London: InTechOpen, 2019.

Note: Studies from a number of flight missions are mentioned. This chapter may be obtained online without charge.



Qian J, Xie G, Zhen J, Duan B, Cao Y, Wang X, Li F, Hu C.

Rules regulating the change in physiological parameters of rats under simulated microgravity and different ambient temperatures.

Am J Civil Eng. 2019;7(1):27-34.

Note: Hindlimb unloading study. This article may be obtained online without charge.



Koga S, Okushima D, Poole DC, Rossiter HB, Kondo N, Barstow TJ.

Unaltered V̇O2 kinetics despite greater muscle oxygenation during heavy-intensity two-legged knee extension versus cycle exercise in humans.

Am J Physiol Regul Integr Comp Physiol. 2019 May 1. [Epub ahead of print]



Konda NN, Karri RS, Winnard A, Nasser M, Evetts S, Boudreau E, Caplan N, Gradwell D, Velho RM.

A comparison of exercise interventions from bed rest studies for the prevention of musculoskeletal loss.

npj Microgravity. 2019 May 8;5(1):12. Review.

Note: Bed rest studies are reviewed. This article may be obtained online without charge.



Sharlo K, Paramonova I, Turtikova O, Tyganov SA, Shenkman BS.

Plantar mechanical stimulation prevents calcineurin/NFATc1 inactivation and slow-to-fast fiber-type shift in rat soleus muscle under hindlimb unloading.

J Appl Physiol (1985). 2019 May 2. [Epub ahead of print]

Note: Hindlimb unloading study.



Yang H, Xu X, Bullock W, Main RP.

Adaptive changes in micromechanical environments of cancellous and cortical bone in response to in vivo loading and disuse.

J Biomech. 2019 Apr 19. [Epub ahead of print]

Note: Hindlimb unloading study. Cyclic compressive loading was used for the loading component of the experiment.



Caudell DL, Michalson KT, Andrews RN, Snow WW, Bourland JD, DeBo RJ, Cline JM, Sempowski GD, Register TC.

Transcriptional profiling of non-human primate lymphoid organ responses to total-body irradiation.

Radiat Res. 2019 May 6. [Epub ahead of print]



Mukherjee S, Laiakis EC, Fornace AJ Jr, Amundson SA.

Impact of inflammatory signaling on radiation biodosimetry: Mouse model of inflammatory bowel disease.

BMC Genomics. 2019 May 2;20(1):329.

Note: This article may be obtained online without charge.



Pei W, Hu W, Chai Z, Zhou G.

Current status of space radiobiological studies in China.

Life Sci Space Res. 2019 May 8. [Article in Press]

Note: The authors review the development of China’s manned space exploration missions and plans for radiobiology research on the China Space Station.



Bannova O, Camba JD, Bishop S.

Projection-based visualization technology and its design implications in space habitats.

Acta Astronaut. 2019 Jul;160:310-6. Epub 2019 May 2.



Guillot A, Debarnot U.

Benefits of motor imagery for human space flight: A brief review of current knowledge and future applications.

Front Physiol. 2019 Apr 11;10:396. Review.

Note: This article may be obtained online without charge.



Stepanova ER, Quesnel D, Riecke BE.

Space—A virtual frontier: How to design and evaluate a virtual reality experience of the overview effect.

Front Digit Humanit. 2019 Apr 25;6:7. Review.

Note: This article may be obtained online without charge.



Pogson JM, Taylor RL, McGarvie L, Bradshaw AP, D’Souza M, Halmagyi GM, Welgampola MS.

The human vestibulo-ocular reflex and saccades: Normal subjects and the effect of age.

J Neurophysiol. 2019 May 1. [Epub ahead of print]



Salter S, Diels C, Herriotts P, Kanarachos S, Thake D.

Motion sickness in automated vehicles with forward and rearward facing seating orientations.

Appl Ergon. 2019 Jul;78:54-61. Epub 2019 Feb 19.



Boschert AL, Elmenhorst D, Gauger P, Li Z, Garcia-Gutierrez MT, Gerlach D, Johannes B, Zange J, Bauer A, Rittweger J.

Sleep is compromised in -12° head down tilt position.

Front Physiol. 2019 Apr 16;10:397.

Note: Head-down tilt study. This article may be obtained online without charge.



Doyle SM, Rigal A, Grones P, Karady M, Barange DK, Majda M, Pařízková B, Karampelias M, Zwiewka M, Pěnčik A, Almqvist F, Ljung K, Novák O, Robert S.

A role for the auxin precursor anthranilic acid in root gravitropism via regulation of PIN-FORMED protein polarity and relocalization in Arabidopsis.

New Phytol. 2019 Apr 30. [Epub ahead of print]



Guo R, Li Y, Lv M.

Design of infinite sliding mode state observer with application to CO2 absorption system of space station.

Acta Astronaut. 2019 May 2. [Article in Press]



Gao J, Liu S, Feng Q, Zhang X, Jiang M, Wang L, Zhang J, Zhang Q.

Subjective and objective quantification of the effect of distraction on physician’s workload and performance during simulated laparoscopic surgery.

Med Sci Monit. 2019 Apr 28;25:3127-32.

Note: The NASA Task Load Index was used. This article may be obtained online without charge.


SpaceRef staff editor.