NASA Spaceline Current Awareness List #826 30 November 2018 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Singh NK, Bezdan D, Checinska Sielaff A, Wheeler K, Mason CE, Venkateswaran K.
Multi-drug resistant Enterobacter bugandensis species isolated from the International Space Station and comparative genomic analyses with human pathogenic strains.
BMC Microbiol. 2018 Nov 23;18(1):175.
https://www.ncbi.nlm.nih.gov/
PIs: C.E. Mason, K. Venkateswaran
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: 2.829
Funding: “This research was funded by a 2012 Space Biology NNH12ZTT001N grant no. 19–12829-26 under Task Order NNN13D111T award to KV, which also funded post-doctoral fellowship for ACS and NKS. We would also like to thank the Epigenomics Core Facility at Weill Cornell Medicine, the Bert L and N Kuggie Vallee Foundation, the WorldQuant Foundation, NASA (NNX14AH50G, NNX17AB26G), the National Institutes of Health (R01ES021006, 1R21AI129851), the Bill and Melinda Gates Foundation (OPP1151054), and the Alfred P. Sloan Foundation (G-2015-13964).”
2
Pattison PM, Tsao JY, Brainard GC, Bugbee B.
LEDs for photons, physiology and food.
Nature. 2018 Nov;563(7732):493-500.
https://www.ncbi.nlm.nih.gov/
PIs: G.C. Brainard, L. Barger
Journal Impact Factor: 41.577
Funding: “P.M.P. and J.Y.T. acknowledge support from the Department of Energy through its Office of Energy Efficiency and Renewable Energy’s Solid-State Lighting Program under contract DE-FE0025912. J.Y.T. acknowledges support from Sandia National Laboratories, a multi-program laboratory managed and operated by National Technology and Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International, Inc., for the US Department of Energy’s National Nuclear Security Administration under contract DE-NA0003525. The work of SSLS, Inc. is carried out on behalf of the US Department of Energy SSL Program, Washington, DC. G.C.B. acknowledges J. Hanifin for discussions, editorial review and referencing; F. Scheer, K. Roecklein and R. Lucas for insights on portions of the text; and B. Warfield for help with the design of Fig. 3. G.C.B. was supported, in part, by NASA grants NNX15AC14, NNX08AD66A and NNX09AM68G; NSF grant EEC-0812056; DOE grant DEEE0008207; The Institute for Integrative Health; and the Philadelphia Section of the Illuminating Engineering Society. B.B. is indebted to 35 years of discussions with colleagues from around the world including T. Volk, M. van Iersel, M. Blonquist, J. Frantz, R. Heins, R. Wheeler and C. Mitchell. B.B. also acknowledges support from NASA grant NNX17AJ31G, the USDA Specialty Crop Research Initiative and the Utah Agricultural Experiment Station.”
3
Steller JG, Alberts JR, Ronca AE.
Oxidative stress as cause, consequence, or biomarker of altered female reproduction and development in the space environment.
Int J Mol Sci. 2018 Nov 23;19(12):E3729. Review.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.687
Funding: “This research received no external funding.” A.E. Ronca is affiliated with NASA Ames Research Center.
4
Zhang Y, Olenick J, Chang C-H, Kozlowski SWJ, Hung H.
TeamSense: Assessing personal affect and group cohesion in small teams through dyadic interaction and behavior analysis with wearable sensors.
Proc ACM Interact Mob Wearable Ubiquitous Technol. 2018 Sep;2(3):1-22.
https://dl.acm.org/citation.
PI: S.W.J. Kozlowski
Note: From the abstract: “This work investigates whether sensing social interactions and individual behaviors with wearable sensors can provide insights into assessing individual affect states and group cohesion. We analyzed wearable sensor data from a team of six crew members who were deployed on a four-month simulation of a space exploration mission at a remote location.”
Journal Impact Factor: Not available for this journal
Funding: “Their research, which generated the data, was supported by the National Aeronautics and Space Administration (NASA; NNX13AM77G, S.W.J. Kozlowski, Principal Investigator).”
5
Moreno-Villanueva M, Feiveson AH, Krieger S, Kay Brinda A, von Scheven G, Bürkle A, Crucian B, Wu H.
Synergistic effects of weightlessness, isoproterenol, and radiation on DNA damage response and cytokine production in immune cells.
Int J Mol Sci. 2018 Nov 21;19(11):E3689.
https://www.ncbi.nlm.nih.gov/
Note: A rotating-wall vessel was used. This article may be obtained online without charge.
Journal Impact Factor: 3.687
Funding: “This research was funded by NASA Space Biology Program and by the German Research Association (DFG) (Grant # MO 2243-2-1).”
6
Sanseverino MJ, Speacht TL, Donahue HJ, Lau AG.
The effects of hind limb suspension and cast mediated immobilization on bone strength properties.
Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:1747-50.
https://www.ncbi.nlm.nih.gov/
PI: H.J. Donahue
Note: Hindlimb unloading and cast immobilization were used.
Journal Impact Factor: Not available for this journal
Funding: “Research Supported by National Space Biomedical Research Institute (MA02802); and National Institutes of Health (R01AR068132, R37 AA0011290 and F32 AA023422), The College of New Jersey Mentored Undergraduate Summer Experience (MUSE) and the New Jersey Space Grant Consortium. (NJSGC) and the VCU School of Engineering Foundation Endowment.”
7
Baulch JE.
Radiation-induced genomic instability, epigenetic mechanisms and the mitochondria: A dysfunctional ménage a trois?
Int J Radiat Biol. 2018 Nov 19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PIs: C.L. Limoli/J.E. Baulch/NSCOR
Journal Impact Factor: 1.97
Funding: “This work was supported by Defense Threat Reduction Agency grant HDTRA 1-16-1-0022 and NASA grant NNX15AI22G to JEB.”
8
Cekanaviciute E, Rosi S, Costes SV.
Central nervous system responses to simulated galactic cosmic rays.
Int J Mol Sci. 2018 Nov 20;19(11):E3669. Review.
https://www.ncbi.nlm.nih.gov/
PIs: S.V. Costes, S. Rosi
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.687
Funding: “This research was funded by NASA grant number #NNX14AC94G (SR) and NASA grant number #NNJ16HP24I (SVC).”
9
Johnson D, Lawrence SE, Livingston EW, Hienz RD, Davis CM, Lau AG.
Modeling space radiation induced bone changes in rat femurs through finite element analysis.
Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:1763-6.
https://www.ncbi.nlm.nih.gov/
PIs: R.D. Hienz, C.M. Davis
Journal Impact Factor: Not available for this journal
Funding: “Research supported by The New Jersey Space Grant Consortium, The College of New Jersey Mentored Undergraduate Research Experience, and NASA Cooperative agreement NCC 9-58 with the National Space Biomedical Research Institute (NBPF04201, NBPF01604, EO00010), and NASA NNX15AC71G.”
10
Rosi S.
The final frontier: Transient microglia reduction after cosmic radiation exposure mitigates cognitive impairments and modulates phagocytic activity.
Brain Circ. 2018 Jul-Sep;4(3):109-13. Review.
https://www.ncbi.nlm.nih.gov/
PI: S. Rosi
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This work was supported by NASA grant NNX14AC94G.”
11
Lifshitz-Assaf H.
Dismantling knowledge boundaries at NASA: The critical role of professional identity in open innovation.
Adm Sci Q. 2018 Dec;63(4):746-82.
https://www.ncbi.nlm.nih.gov/
Note: From the Abstract: “Using a longitudinal in-depth field study at NASA, I investigate how the open, or peer-production, innovation model affects R&D professionals, their work, and the locus of innovation.” The research was conducted within NASA’s Space Life Science Directorate (SLSD). Author acknowledges funding from Harvard University. This article may be obtained online without charge.
______________________________
Other papers of interest:
1
Johnson KT, Taylor S, Fedor S, Jaques N, Chen W, Picard RW.
Vomit comet physiology: Autonomic changes in novice flyers.
Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:1172-6.
https://www.ncbi.nlm.nih.gov/
Note: Parabolic flight results.
2
Strauch SM, Grimm D, Corydon TJ, Kruger M, Bauer J, Lebert M, Wise P, Infanger M, Richter P.
Current knowledge about the impact of microgravity on the proteome.
Expert Rev Proteomics. 2018 Nov 19. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
Note: Flight studies reviewed include MAXUS-9, Shenzhou-8, STS-135, Bion M1, ISS, and parabolic flight. Ground-based studies used centrifugation and clinorotation.
3
Chen Y, Zhang H, Xu J, Yang C, Wu F, Lu X, Chen J, Li K, Wang H, Zhong Y, Nie H, Li Y, Li Y, Dai Z.
Simulated microgravity led to increased brown adipose tissue activity in rats.
Acta Astronaut. 2018 Nov 22. [Article in Press]
https://www.sciencedirect.com/
Note: Hindlimb unloading study.
4
Usik MA, Ogneva IV.
Cytoskeleton structure in mouse sperm and testes after 30 days of hindlimb unloading and 12 hours of recovery.
Cell Physiol Biochem. 2018 Nov;51(1):375-92.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study. This article may be obtained online without charge.
5
Cécile P, Julien A, Andrea A, Agnès C, Cécile CG, Clara T, Christiane D, Lydie C, Daniel B, Marco S, Didier A, Daniel T.
UBE2E1 is preferentially expressed in the cytoplasm of slow-twitch fibers and protects skeletal muscles from exacerbated atrophy upon dexamethasone treatment.
Cells. 2018 Nov 16;7(11):E214.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
6
Hyatt H, Deminice R, Yoshihara T, Powers SK.
Mitochondrial dysfunction induces muscle atrophy during prolonged inactivity: A review of the causes and effects.
Arch Biochem Biophys. 2018 Nov 16. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
7
Mirzoev TM, Tyganov SA, Petrova IO, Shenkman BS.
Acute recovery from disuse atrophy: The role of stretch-activated ion channels in the activation of anabolic signaling in skeletal muscle.
Am J Physiol Endocrinol Metab. 2018 Nov 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
8
Oliveira JRS, Mohamed JS, Myers MJ, Brooks MJ, Alway SE.
Effects of hindlimb suspension and reloading on gastrocnemius and soleus muscle mass and function in geriatric mice.
Exp Gerontol. 2018 Nov 16;115:19-31.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study. This article may be obtained online without charge.
9
Kuehn F, Adiliaghdam F, Hamarneh SR, Vasan R, Liu E, Liu Y, Ramirez JM, Hoda RS, Munoz AR, Ko FC, Armanini M, Brooks DJ, Bouxsein ML, Demay MB, Hodin RA.
Loss of intestinal alkaline phosphatase leads to distinct chronic changes in bone phenotype.
J Surg Res. 2018 Dec;232:325-31.
https://www.ncbi.nlm.nih.gov/
10
Veeriah V, Paone R, Chatterjee S, Teti A, Capulli M.
Osteoblasts regulate angiogenesis in response to mechanical unloading.
Calcif Tissue Int. 2018 Nov 21. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: A rotating wall vessel bioreactor was used.
11
Múčka V, Červenák J, Reimitz D, Čuba V, Bláha P, Neužilová B.
Effects of irradiation conditions on the radiation sensitivity of microorganisms in the presence of OH-radical scavengers.
Int J Radiat Biol. 2018 Nov 19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
12
MacNeilage PR, Glasauer S.
Gravity perception: The role of the cerebellum.
Curr Biol. 2018 Nov 19;28(22):R1296-R1298.
https://www.ncbi.nlm.nih.gov/
13
Dużmańska N, Strojny P, Strojny A.
Can simulator sickness be avoided? A review on temporal aspects of simulator sickness.
Front Psychol. 2018 Nov 6;9:2132.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
14
Nalivaiko E.
Thermoregulation and nausea.
Handb Clin Neurol. 2018;156:445-56.
https://www.ncbi.nlm.nih.gov/
15
Favre-Bulle IA, Vanwalleghem G, Taylor MA, Rubinsztein-Dunlop H, Scott EK.
Cellular-resolution imaging of vestibular processing across the larval zebrafish brain.
Curr Biol. 2018 Nov 1. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
16
Ma CW, Kwan PY, Wu KL, Shum DK, Chan YS.
Regulatory roles of perineuronal nets and semaphorin 3A in the postnatal maturation of the central vestibular circuitry for graviceptive reflex.
Brain Struct Funct. 2018 Nov 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
17
Migault G, van der Plas TL, Trentesaux H, Panier T, Candelier R, Proville R, Englitz B, Debrégeas G, Bormuth V.
Whole-brain calcium imaging during physiological vestibular stimulation in larval zebrafish.
Curr Biol. 2018 Nov 2. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
18
Arico P, Reynal M, Imbert JP, Hurter C, Borghini G, Di Flumeri G, Sciaraffa N, Di Florio A, Terenzi M, Ferreira A, Pozzi S, Betti V, Marucci M, Pavone E, Telea AC, Babiloni F.
Human-machine interaction assessment by neurophysiological measures: A study on professional air traffic controllers.
Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:4619-22.
https://www.ncbi.nlm.nih.gov/
19
Cinelli I.
Space medicine requirements open to innovation in biomedical engineering.
Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:973-6.
https://www.ncbi.nlm.nih.gov/
20
Villoslada A, Rivera C, Escudero N, Martin F, Blanco D, Moreno L.
Hand exo-muscular system for assisting astronauts during extravehicular activities.
Soft Robot. 2018 Nov 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
21
Clark G, Roux SJ.
Role of Ca2+ in mediating plant responses to extracellular ATP and ADP.
Int J Mol Sci. 2018 Nov 14;19(11):E3590. Review.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
22
Liu H, Liu B, Chen X, Zhu H, Zou C, Men S.
AUX1 acts upstream of PIN2 in regulating root gravitropism.
Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):433-6.
https://www.ncbi.nlm.nih.gov/
23
Xie J, Zheng H.
Arabidopsis flowering induced by photoperiod under 3-D clinostat rotational simulated microgravity.
Acta Astronaut. 2018 Nov 23. [Article in Press]
https://www.sciencedirect.com/
Note: A 3-D clinostat was used.
24
Zhu G, Liu G, Liu D, Chen H, Fang C, Yi Y, Li M, Xie B, Liu H.
Research on the hydrolysis of human urine using biological activated carbon and its application in bioregenerative life support system.
Acta Astronaut. 2018 Nov 22. [Article in Press]
https://www.sciencedirect.com/
25
Nayar SK, Musto L, Fernandes R, Bharathan R.
Validation of a virtual reality laparoscopic appendicectomy simulator: A novel process using cognitive task analysis.
Ir J Med Sci. 2018 Nov 19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used.
