NASA Spaceline Current Awareness List #820 19 October 2018 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Koppelmans V, Scott JM, Downs ME, Cassady KE, Yuan P, Pasternak O, Wood SJ, De Dios YE, Gadd NE, Kofman I, Riascos R, Reuter-Lorenz PA, Bloomberg JJ, Mulavara AP, Ploutz-Snyder LL, Seidler RD.
Exercise effects on bed rest-induced brain changes.
PLoS One. 2018 Oct 11;13(10):e0205515.
https://www.ncbi.nlm.nih.gov/
PIs: R.D. Seidler; V. Koppelmans, NSBRI Postdoctoral Fellowship Program
Note: Head-down tilt bed rest study. This article may be obtained online without charge.
Journal Impact Factor: 2.766
Funding: “This work is supported by grants from the following institutions: 1) The National Space Biomedical Research Institute (http://nsbri.org/funding/): a. NASA cooperative agreement NCC 9-58 awarded to RDS. b. MA02701 awarded to RDS. c. PF04101 awarded to VK. 2) The National Aeronautics and Space Administration (https://www.nasa.gov/about/
2
Fajardo-Cavazos P, Morrison MD, Miller KM, Schuerger AC, Nicholson WL.
Transcriptomic responses of Serratia liquefaciens cells grown under simulated Martian conditions of low temperature, low pressure, and CO2-enriched anoxic atmosphere.
Sci Rep. 2018 Oct 8;8(1):14938.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.122
Funding: “This work was funded by the National Aeronautics and Space Administration (NASA) Planetary Protection grant NNX12AJ84G.”
3
Laurie SS, Macias BR, Dunn JT, Young M, Stern C, Lee SMC, Stenger MB.
Optic disc edema after 30 days of strict head-down tilt bed rest.
Ophthalmology. 2018 Oct 8. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: S.S. Laurie
Note: Head-down tilt bed rest study.
Journal Impact Factor: 7.479
Funding: “National Aeronautics and Space Administration Human Research Program Grant #NNJ14ZSA001N (SSL).”
4
Liu J, Li X, Zhang D, Jiao J, Wu L, Hao F, Qin YX.
Acceleration of bone defect healing and regeneration by low-intensity ultrasound radiation force in a rat tibial model.
Ultrasound Med Biol. 2018 Oct 1. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: Y.X. Qin
Journal Impact Factor: 2.645
Funding: “This research was kindly supported by the National Institutes of Health (Grants R01AR52379, AR61821 and AR49286), the U.S. Army Medical Research and Materiel Command and the National Space Biomedical Research Institute through NASA Cooperative Agreement NCC9-58. The first author was partially supported by the China National Natural Science Foundation (Grant 81500869).”
5
Zanni G, Deutsch HM, Rivera PD, Shih HY, LeBlanc JA, Amaral WZ, Lucero MJ, Redfield RL, DeSalle MJ, Chen BPC, Whoolery CW, Reynolds RP, Yun S, Eisch AJ.
Whole-body 12C irradiation transiently decreases mouse hippocampal dentate gyrus proliferation and immature neuron number, but does not change new neuron survival rate.
Int J Mol Sci. 2018 Oct 9;19(10):E3078.
https://www.ncbi.nlm.nih.gov/
PIs: A.J. Eisch, B.P.C. Chen
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.687
Funding: “Research supported by NASA grants NNX07AP84G (to BPCC and AJE), NNX12AB55G (to AJE and BPC), and NNX15AE09G (to AJE) and NIH grants to AJE DA007290, DA023555, and DA016765. CWW was supported by an NIH Institutional Training grant (DA007290, PI: AJE, DW Self).”
6
Hanifin JP, Lockley SW, Cecil K, West K, Jablonski M, Warfield B, James M, Ayers M, Byrne B, Gerner E, Pineda C, Rollag M, Brainard GC.
Randomized trial of polychromatic blue-enriched light for circadian phase shifting, melatonin suppression, and alerting responses.
Physiol Behav. 2018 Oct 5. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PIs: G.C. Brainard, S.W. Lockley
Journal Impact Factor: 2.517
Funding: “Primary research support was provided by the National Space Biomedical Research Institute through NASA NCC 9-58. Additional support was provided by the Philadelphia Section of the Illuminating Engineering Society.”
______________________________
Other papers of interest:
1
Zangheri M, Mirasoli M, Guardigli M, Di Nardo F, Anfossi L, Baggiani C, Simoni P, Benassai M, Roda A.
Chemiluminescence-based biosensor for monitoring astronauts’ health status during space missions: Results from the International Space Station.
Biosens Bioelectron. 2018 Sep 17. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: ISS results.
2
Yamagishi A, Kawaguchi Y, Hashimoto H, Yano H, Imai E, Kodaira S, Uchihori Y, Nakagawa K.
Environmental data and survival data of Deinococcus aetherius from the Exposure Facility of the Japan Experimental Module of the International Space Station obtained by the Tanpopo Mission.
Astrobiology. 2018 Oct 5. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: ISS results.
3
Wei Y, Zhang J, Xu S, Peng X, Yan X, Li X, Wang H, Chang H, Gao Y.
Controllable oxidative stress and tissue specificity in major tissues during the torpor-arousal cycle in hibernating Daurian ground squirrels.
Open Biol. 2018 Oct 10;8(10):180068.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
4
Horii Y, Shiina T, Shimizu Y.
The mechanism enabling hibernation in mammals.
Adv Exp Med Biol. 2018;1081:45-60.
https://www.ncbi.nlm.nih.gov/
5
Huang W, Chen C, Liu X.
Hindlimb suspension-induced cell apoptosis in the posterior parietal cortex and lateral geniculate nucleus: Corresponding changes in cFos protein and the PI3K/Akt signaling pathway.
Acta Neurobiol Exp (Wars). 2018;78(3):220-30.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study. This article may be obtained online without charge.
6
Edgell H, Grinberg A, Beavers KR, Gagné N, Hughson RL.
Efficacy of fluid loading as a countermeasure to the hemodynamic and hormonal changes of 28-h head-down bed rest.
Physiol Rep. 2018 Sep;6(19):e13874.
https://www.ncbi.nlm.nih.gov/
Note: Head-down tilt bed rest study; lower body negative pressure was used. This article may be obtained online without charge.
7
Petty HR.
A new interpretation of the mechanism underlying visual anomalies of astronauts.
Exp Eye Res. 2019 Jan;178:133-4. Epub 2018 Oct 4.
https://www.ncbi.nlm.nih.gov/
Note: The author proposes “that transient membrane defects couple lipid damage to certain physiological changes and cell death during tissue exposure to HZEs.” This article may be obtained online without charge.
8
Ninfali C, Siles L, Darling DS, Postigo A.
Regulation of muscle atrophy-related genes by the opposing transcriptional activities of ZEB1/CtBP and FOXO3.
Nucleic Acids Res. 2018 Oct 10. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
9
Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, Greenblatt MB, Mangala LS, Lopez-Berestein G, Kirsch DG, Sood AK, Zhao L, Zhao B.
Bone protection by inhibition of microRNA-182.
Nat Commun. 2018 Oct 5;9(1):4108.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
10
Ma L, Kazama Y, Hirano T, Morita R, Tanaka S, Abe T, Hatakeyama S.
LET dependence on killing effect and mutagenicity in the model filamentous fungus Neurospora crassa.
Int J Radiat Biol. 2018 Oct 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
11
Xiang S, Zhou Y, Fu J, Zhang T.
rTMS pre-treatment effectively protects against cognitive and synaptic plasticity impairments induced by simulated microgravity in mice.
Behav Brain Res. 2018 Oct 4. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study.
12
Darioli V, Taffé P, Carron PN, Dami F, Vallotton L, Yersin B, Schoettker P, Pasquier M.
Evaluation of the discriminative performance of the prehospital National Advisory Committee for Aeronautics score regarding 48-h mortality.
Eur J Emerg Med. 2018 Oct 10. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The National Advisory Committee for Aeronautics (NACA) score was used.
13
Liu G, Bollier D, Gübeli C, Peter N, Arnold P, Egli M, Borghi L.
Simulated microgravity and the antagonistic influence of strigolactone on plant nutrient uptake in low nutrient conditions.
npj Microgravity. 2018 Oct 17;4(1):20.
https://www.nature.com/
Note: A 3-D random positioning machine was used. This article may be obtained online without charge.
14
Wolff SA, Palma CF, Marcelis L, Kittang Jost AI, van Delden SH.
Testing new concepts for crop cultivation in space: Effects of rooting volume and nitrogen availability.
Life (Basel). 2018 Oct 6;8(4):E45.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
15
Kalbarczyk KZ, Mazeau EJ, Rapp KM, Marchand N, Koffas MAG, Collins CH.
Engineering Bacillus megaterium strains to secrete cellulases for synergistic cellulose degradation in a microbial community.
ACS Synth Biol. 2018 Oct 3. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
16
Zheng C, Jin FQ, Trippe BL, Wu J, Chalfie M.
Inhibition of cell fate repressors secures the differentiation of the touch receptor neurons of Caenorhabditis elegans.
Development. 2018 Oct 5. [Epub ahead of print]
