NASA Spaceline Current Awareness List #814 7 September 2018 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Kim KJ, Gimmon Y, Sorathia S, Beaton KH, Schubert MC.
Exposure to an extreme environment comes at a sensorimotor cost.
npj Microgravity. 2018 Sep 5;4(1):17.
https://www.nature.com/
PI: M.C. Schubert
Note: From the abstract: “The aims of the present study were…(1) to develop a Portable Sensorimotor Assessment Platform (PSAP) to enable a crewmember to independently and quickly assess his/her sensorimotor function during the NASA’s Extreme Environment Mission Operations (NEEMO) and (2) to investigate changes in performance of static posture, tandem gait, and lower limb ataxia due to exposure in an extreme environment.” This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “Funding was provided by private donations and in part by NASA through the Human Research Program grant (NNX10AO19G) and the Department of Defense (W81XWH-15-1-0442).”
2
Smith DJ, Ravichandar JD, Jain S, Griffin DW, Yu H, Tan Q, Thissen J, Lusby T, Nicoll P, Shedler S, Martinez P, Osorio A, Lechniak J, Choi S, Sabino K, Iverson K, Chan L, Jaing C, McGrath J.
Airborne bacteria in Earth’s lower stratosphere resemble taxa detected in the troposphere: Results from a New NASA Aircraft Bioaerosol Collector (ABC).
Front Microbiol. 2018 Aug 14;9:1752.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.019
Funding: “Our study was funded by the NASA Office of the Chief Scientist (FY17 Science Innovation Fund award), a FY17/18 Biodiversity grant from the NASA Earth Science Division, internal awards from NASA Ames Research Center and Lawrence Livermore National Laboratory (LLNL) in FY18, and the U.S. Geological Survey’s Environmental Health Toxic Substances Hydrology and Contaminate Biology Programs.”
3
Matelli JA, Goebel K.
Resilience evaluation of the environmental control and life support system of a spacecraft for deep space travel.
Acta Astronaut. 2018 Aug 28. [Article in Press]
http://www.sciencedirect.com/
Journal Impact Factor: 2.227
Funding: “FAPESP – São Paulo Research Foundation, for sponsoring the postdoc internship of the first author at NASA Ames Research Center (Grant number: 2016/19255-7).” J.A. Matelli was a visiting scientist at NASA Ames Research Center during 2017.
Please Note: The September issue of Medicine & Science in Sports & Exercise contains a Special Section of articles about the NASA 70-Day Bed Rest Study. Six of the articles appeared ahead of print in earlier SPACELINE Current Awareness Lists; the Commentary was added at publication. The articles are listed again here as a group.
4
Grassi B.
Bed rest studies as analogs of conditions encountered in space and in diseases.
Med Sci Sports Exerc. 2018 Sep;50(9):1907-8.
https://www.ncbi.nlm.nih.gov/
Note: This Commentary introduces the Special Section in the September issue of Medicine & Science in Sports & Exercise about the NASA 70-Day Bed Rest Study.
5
Cromwell RL, Scott JM, Downs M, Yarbough PO, Zanello SB, Ploutz-Snyder L.
Overview of the NASA 70-day bed rest study.
Med Sci Sports Exerc. 2018 Sep;50(9):1909-19. Epub 2018 Mar 22.
https://www.ncbi.nlm.nih.gov/
PIs: R.L. Cromwell, L.L. Ploutz-Snyder
Note: Head-down tilt bed rest study. This article also appeared in SPACELINE Current Awareness List #793, 6 Apr 2018.
Journal Impact Factor: 4.291
Funding: “Study infrastructure and operations were supported by the NASA HRP Flight Analogs Project, and the University of Texas Medical Branch, Institute for Translational Sciences – Clinical Research Center (ITS-CRC) through an NIH/NCATS Center for Translational Science Award (UL1TR000071). Individual research studies were supported by the NASA Human Research Program (HRP) and the National Space Biomedical Research Institute.”
6
Ploutz-Snyder LL, Downs M, Goetchius E, Crowell B, English KL, Ploutz-Snyder R, Ryder J, Dillon EL, Sheffield-Moore M, Scott JM.
Exercise training mitigates multi-system deconditioning during bed rest.
Med Sci Sports Exerc. 2018 Sep;50(9):1920-8. Epub 2018 Mar 26.
https://www.ncbi.nlm.nih.gov/
PIs: L.L. Ploutz-Snyder, R.L. Cromwell
Note: Bed rest study. This article also appeared in SPACELINE Current Awareness List #805, 29 Jun 2018.
Journal Impact Factor: 4.291
Funding: “This study was supported by the Human Research Program of the National Aeronautics and Space Administration (NASA) and National Space Biomedical Research Institute (NSBRI NNJ11ZSA002N)….This study was conducted with the support of the Institute for Translational Sciences at the University of Texas Medical Branch, supported in part by a Clinical and Translational Science Award (UL1TR000071) from the National Center for Advancing Translational Sciences, National Institutes of Health.”
7
Dillon EL, Sheffield-Moore M, Durham WJ, Ploutz-Snyder LL, Ryder JW, Danesi CP, Randolph KM, Gilkison CR, Urban RJ.
Efficacy of testosterone plus NASA exercise countermeasures during head-down bed rest.
Med Sci Sports Exerc. 2018 Sep;50(9):1929-39. Epub 2018 Mar 26.
https://www.ncbi.nlm.nih.gov/
PIs: R.J. Urban, R.L. Cromwell
Note: Head-down tilt bed rest study. This article also appeared in SPACELINE Current Awareness List #794, 13 Apr 2018.
Journal Impact Factor: 4.291
Funding: “This study was funded by the National Aeronautics and Space Administration (#NNX10AP86G, RJU/MSM) and conducted with the support of the Institute for Translational Sciences at the University of Texas Medical Branch, supported in part by a Clinical and Translational Science Award (UL1TR000071) from the National Center for Advancing Translational Sciences, National Institutes of Health.”
8
Scott JM, Martin D, Ploutz-Snyder R, Downs M, Dillon EL, Sheffield-Moore M, Urban RJ, Ploutz-Snyder LL.
Efficacy of exercise and testosterone to mitigate atrophic cardiovascular remodeling.
Med Sci Sports Exerc. 2018 Sep;50(9):1940-9. Epub 2018 Mar 22.
https://www.ncbi.nlm.nih.gov/
PIs: R.J. Urban, L.L. Ploutz-Snyder, R.L. Cromwell
Note: Head-down tilt bed rest study. This article also appeared in SPACELINE Current Awareness List #793, 6 Apr 2018.
Journal Impact Factor: 4.291
Funding: “This study was supported by the Human Research Program of the National Aeronautics and Space Administration (NASA), and the Institute for Translational Sciences at the University of Texas Medical Branch, supported in part by a Clinical and Translational Science Award (UL1TR000071) from the National Center for Advancing Translational Sciences, National Institutes of Health….JMS is supported by grants from AKTIV Against Cancer, and the Memorial Sloan Kettering Cancer Center Support Grant/Core Grant (P30 CA008748).” The authors report that the following grants should also be acknowledged: NASA (NNX10AP86G) to Dr. Randall J. Urban, NASA (NNX16AO74G) to Dr. Lori L. Ploutz-Snyder, NSBRI (MA02801) Dr. Lori L. Ploutz-Snyder, and National Center for Advancing Translational Sciences (UL1TR000071) to Dr. Allan R. Brasier.
9
Murach KA, Minchev K, Grosicki GJ, Lavin K, Perkins RK, Ryder JW, Scott J, Ploutz-Snyder L, Trappe TA, Trappe S.
Myocellular responses to concurrent flywheel training during 70 days of bed rest.
Med Sci Sports Exerc. 2018 Sep;50(9):1950-60. Epub 2018 Mar 22.
https://www.ncbi.nlm.nih.gov/
PI: R.L. Cromwell
Note: Head-down tilt bed rest study. This article also appeared in SPACELINE Current Awareness List #793, 6 Apr 2018.
Journal Impact Factor: 4.291
Funding: “This work was supported by: the National Aeronautics and Space Administration, NNJ06HF59G; the Institute for Translational Sciences at the University of Texas Medical Branch, supported in part by a Clinical and Translational Science Award (UL1TR000071) from the National Center for Advancing Translational Sciences, National Institutes of Health; and the NASA Flight Analogs Project (planning and implementation).”
10
Mulavara AP, Peters BT, Miller CA, Kofman IS, Reschke MF, Taylor LC, Lawrence EL, Wood SJ, Laurie SS, Lee SMC, Buxton RE, May-Phillips TR, Stenger MB, Ploutz-Snyder LL, Ryder JW, Feiveson AH, Bloomberg JJ.
Physiological and functional alterations after spaceflight and bed rest.
Med Sci Sports Exerc. 2018 Sep;50(9):1961-80. Epub 2018 Apr 3.
https://www.ncbi.nlm.nih.gov/
PIs: J.J. Bloomberg, R.L. Cromwell
Note: ISS and head-down tilt bed rest study results. This article also appeared in SPACELINE Current Awareness List #794, 13 Apr 2018.
Journal Impact Factor: 4.291
Funding: “This study was conducted with the support from NASA’s Human Research Program and the Institute for Translational Sciences at the University of Texas Medical Branch, supported in part by a Clinical and Translational Science Award (UL1TR000071) from the National Center for Advancing Translational Sciences, National Institutes of Health.”
______________________________
Other papers of interest:
1
Kobayashi A, Kim HJ, Tomita Y, Miyazawa Y, Fujii N, Yano S, Yamazaki C, Kamada M, Kasahara H, Miyabayashi S, Shimazu T, Fusejima Y, Takahashi H.
Circumnutational movement in rice coleoptiles involves the gravitropic response: Analysis of an agravitropic mutant and space-grown seedlings.
Physiol Plant. 2018 Aug 29. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: ISS results.
2
Treat MD, Scholer L, Barrett B, Khachatryan A, McKenna AJ, Reyes T, Rezazadeh A, Ronkon CF, Samora D, Santamaria JF, Silva Rubio C, Sutherland E, Richardson J, Lighton JRB, van Breukelen F.
Extreme physiological plasticity in a hibernating basoendothermic mammal, Tenrec ecaudatus.
J Exp Biol. 2018 Aug 29. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
3
Gries KJ, Raue U, Perkins RK, Lavin KM, Overstreet BS, D’Acquisto LJ, Graham B, Finch WH, Kaminsky LA, Trappe TA, Trappe SW.
Cardiovascular and skeletal muscle health with lifelong exercise.
J Appl Physiol (1985). 2018 Aug 30. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
4
Song H, Cho S, Lee HY, Lee H, Song W.
The effects of progressive resistance exercise on recovery rate of bone and muscle in a rodent model of hindlimb suspension.
Front Physiol. 2018 Aug 13;9:1085.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study. This article may be obtained online without charge.
5
Huyan T, Du Y, Dong D, Li Q, Zhang R, Yang J, Yang Z, Li J, Shang P.
Osteoclast-derived exosomes inhibit osteogenic differentiation through Wnt/β-catenin signaling pathway in simulated microgravity model.
Acta Astronaut. 2018 Aug 29. [Article in Press]
http://www.sciencedirect.com/
Note: A Random Positioning Machine was used.
6
Hubert G, Aubry S.
Analysis of exposure to solar and galactic cosmic radiations of flights representative of the European international air traffic.
Radiat Res. 2018 Sep;190(3):271-81.
https://www.ncbi.nlm.nih.gov/
7
Pannkuk EL, Laiakis EC, Garcia M, Fornace AJ Jr, Singh VK.
Nonhuman primates with acute radiation syndrome: Results from a global serum metabolomics study after 7.2 Gy total-body irradiation.
Radiat Res. 2018 Sep 5. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
8
Wang B, Tanaka K, Ninomiya Y, Maruyama K, Vares G, Katsube T, Murakami M, Liu C, Fujimori A, Fujita K, Liu Q, Eguchi-Kasai K, Nenoi M.
Increased hematopoietic stem cells/hematopoietic progenitor cells measured as endogenous spleen colonies in radiation-induced adaptive response in mice (Yonezawa Effect).
Dose Response. 2018 Jul-Sep;16(3):1-10.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
9
Wang Y, Zhou X, Zhao B, Ren X, Chen Y, Si J, Zhou R, Gan L, Zhang H.
Early embryonic exposure of ionizing radiations disrupts zebrafish pigmentation.
J Cell Physiol. 2018 Aug 24. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
10
Zhao F, van Rietbergen B, Ito K, Hofmann S.
Flow rates in perfusion bioreactors to maximise mineralisation in bone tissue engineering in vitro.
J Biomech. 2018 Aug 13. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
11
Narayana R, Fliegmann J, Paponov IA, Maffei ME.
Reduction of geomagnetic field (GMF) to near null magnetic field (NNMF) affects Arabidopsis thaliana root mineral nutrition.
Life Sci Space Res. 2018 Sep 1. [Article in Press]
http://www.sciencedirect.com/
12
Lee CY, Chan H, Ujiie H, Fujino K, Kinoshita T, Irish JC, Yasufuku K.
Novel thoracoscopic navigation system with augmented real-time image guidance for chest wall tumors.
Ann Thorac Surg. 2018 Aug 15. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used.
13
Zavlin D, Chegireddy V, Nguyen-Lee JJ, Shih L, Nia AM, Friedman JD, Echo A.
Training effects of visual stroboscopic impairment on surgical performance: A randomized-controlled trial.
J Surg Educ. 2018 Aug 18. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used.
