NASA Spaceline Current Awareness List #809 27 July 2018 (Space Life Science Research Results)
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Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,
SPACELINE@nasaprs.com.
Papers deriving from NASA support:
1
Makedonas G, Choukèr A, Mehta S, Simpson RJ, Stowe R, Sams C, Pierson D, Crucian B.
Mechanistic clues to overcome spaceflight-induced immune dysregulation.
Curr Pathobiol Rep. 2018 July 19. [Article in Press] Review.
https://link.springer.com/
Note: ISS results. This article is part of the journal’s Topical Collection on the “Effects
of the Space Environments on Human Pathobiology.”
Journal Impact Factor:
Not available for this journal
Funding:
No
funding cited. The following authors are affiliated with NASA Johnson
Space Center or have been funded by NASA for related projects: G.
Makedonas, S. Mehta, R. Simpson, R. Stowe,
C. Sams, D. Pierson, and B. Crucian.
2
Caruso JF, Voor M, Jaggers J, Symons TB, Stith J, Bai L, Selimovic E, Carter K, Daily J.
Musculoskeletal outcomes from chronic high-speed, high-impulse resistance exercise.
Int J Sports Med. 2018 Jul 19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Journal Impact Factor: 2.084
Funding:
“This project was funded by a grant provided by The [NASA] Kentucky Space Grant Consortium (Announcement: RFP-16-001).”
3
Wang J, Song J, Clark GB, Roux SJ.
AnnAt1 and AnnAt2 function in post-phloem sugar transport in root tips to affect primary root growth.
Plant Physiol. 2018 Jul 17. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI:
S.J. Roux
Note:
This article may be obtained online without charge.
Journal Impact Factor: 6.456
Funding: “This work was supported by the National Science Foundation grant [IOS-1027514
to S.J.R. and G.C.], and the National Aeronautics and Space Administration grant [NNX13AM54G to S.J.R. and G.C.]”
______________________________
Other papers of interest:
1
Baio J, Martinez AF, Silva I, Hoehn CV, Countryman S, Bailey L, Hasaniya N, Pecaut MJ, Kearns-Jonker M.
Cardiovascular
progenitor cells cultured aboard the International Space Station
exhibit altered developmental and functional properties.
npj Microgravity. 2018 Jul 26;4(1):13.
https://www.nature.com/
Note: ISS results. This article may be obtained online without charge.
2
Sakai T, Moteki Y, Takahashi T, Shida K, Kiwaki M, Shimakawa Y, Matsui A, Chonan O, Morikawa K, Ohta T, Ohshima H, Furukawa S.
Probiotics
into outer space: Feasibility assessments of encapsulated freeze-dried
probiotics during 1 month’s storage on the International Space Station.
Sci Rep. 2018 Jul 16;8(1):10687.
https://www.ncbi.nlm.nih.gov/
Note: ISS results. This article may be obtained online without charge.
3
Blanco MB, Dausmann KH, Faherty SL, Yoder AD.
Tropical heterothermy is “cool”: The expression of daily torpor and hibernation in primates.
Evol Anthropol. 2018 Jul 17. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
4
Frigault JJ, Gaudet JD, Morin PJ.
Investigating Nrf2-associated non-coding RNAs in the hibernating ground squirrel,
Ictidomys tridecemlineatus.
J Therm Biol. 2018 Jul;75:38-44.
https://www.ncbi.nlm.nih.gov/
5
Xu D, Guo YB, Zhang M, Sun YQ.
The subsequent biological effects of simulated microgravity on endothelial cell growth in HUVECs.
Chin J Traumatol. 2018 Jun 28. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
A rotary cell culture system was used. This article may be obtained online without charge.
6
de
Sire R, Rizzatti G, Ingravalle F, Pizzoferrato M, Petito V, Lopetuso L,
Graziani C, de Sire A, Mentella MC, Mele MC, Gasbarrini A, Scaldaferri
F.
Skeletal muscle-gut axis: Emerging mechanisms of sarcopenia for intestinal and extra intestinal diseases.
Minerva Gastroenterol Dietol. 2018 Jul 18. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
Note:
From
the abstract: “This review summarized the potential pathways linking
gut with muscle, in particular in conditions as sarcopenia and cachexia.
The main emerging pathways implicated
in the skeletal muscle-gut axis are: the myostatin/activin signaling
pathway, the IGF1/PI3K/AKT/mTOR signaling pathway, which results
suppressed, the NF-kB signaling pathway and the FOXO signaling pathway.”
7
Bathgate KE, Bagley JR, Jo E, Talmadge RJ, Tobias IS, Brown LE, Coburn JW, Arevalo JA, Segal NL, Galpin AJ.
Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits.
Eur J Appl Physiol. 2018 Jul 14. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
8
Schaller
SJ, Nagashima M, Schonfelder M, Sasakawa T, Schulz F, Khan MAS, Kem WR,
Schneider G, Schlegel J, Lewald H, Blobner M, Martyn JAJ.
GTS-21
attenuates loss of body mass, muscle mass, and function in rats having
systemic inflammation with and without disuse atrophy.
Pflugers Arch. 2018 Jul 13. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Immobilization of one hindlimb was accomplished via pinning of knee and ankle joints.
9
Schoenrock B, Zander V, Dern S, Limper U, Mulder E, Veraksits A, Viir R, Kramer A, Stokes MJ, Salanova M, Peipsi A, Blottner D.
Bed rest, exercise countermeasure and reconditioning effects on the human resting muscle tone system.
Front Physiol. 2018 Jul 3;9:810.
https://www.ncbi.nlm.nih.gov/
Note: Bed rest study. This article may be obtained online without charge.
10
Cunningham HC, West DWD, Baehr LM, Tarke FD, Baar K, Bodine SC, Christiansen BA.
Age-dependent bone loss and recovery during hindlimb unloading and subsequent reloading in rats.
BMC Musculoskelet Disord. 2018 Jul 18;19(1):223.
https://www.ncbi.nlm.nih.gov/
Note:
Hindlimb unloading study. This article may be obtained online without charge.
11
Murray D, Mirzayans R, McBride WH.
Defenses against pro-oxidant forces – Maintenance of cellular and genomic integrity and longevity.
Radiat Res. 2018 Jul 24. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
12
Wei W, Wang J, He J, Xie X.
Serum microRNA as noninvasive indicator for space radiation.
Acta Astronaut. 2018 Jul 25. [Article in Press]
https://www.sciencedirect.com/
13
Shayman CS, Seo JH, Oh Y, Lewis RF, Peterka RJ, Hullar TE.
The relationship between vestibular sensitivity and multisensory temporal integration.
J Neurophysiol. 2018 Jul 18. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
14
Okamoto T, Takatani S, Noutoshi Y, Motose H, Takahashi T.
Omeprazole enhances mechanical stress-induced root growth reduction in
Arabidopsis thaliana.
Plant Cell Physiol. 2018 Jul 14. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
15
Tsugama D, Liu S, Fujino K, Takano T.
Calcium signalling regulates the functions of the bZIP protein VIP1 in touch responses in
Arabidopsis thaliana.
Ann Bot. 2018 Jul 14. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
16
Zhao Q, Wang W, Gao S, Sun Y.
Analysis of DNA methylation alterations in rice seeds induced by different doses of carbon-ion radiation.
J Radiat Res. 2018 Jul 18. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
This article may be obtained online without charge.
17
Hao Z, Li L, Fu Y, Liu H.
The
influence of bioregenerative life-support system (BLSS) dietary
structure and lifestyle on the gut microbiota: A 105-day ground-based
space simulation in Lunar Palace
1.
Environ Microbiol. 2018 Jul 12. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note:
The study was conducted for China’s Lunar Palace 1, a bioregenerative life support system.
18
Besharati A, Daneshmandi H, Zareh K, Fakherpour A, Zoaktafi M.
Work-related musculoskeletal problems and associated factors among office workers.
Int J Occup Saf Ergon. 2018 Jul 17. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: The NASA Task Load Index was used.
Please Note:
Gravitational Biology I: Gravity Sensing and Graviorientation in Microorganisms and Plants,
is a new book from the “SpringerBriefs in Space Life Sciences” series.
From the publisher’s website: “This book summarizes what is currently
known about gravity
sensing and response mechanisms in microorganisms, fungi, lower and
higher plants; starting from the historical eye-opening experiments from
the 19th century up to today’s extremely rapid advancing cellular,
molecular and biotechnological research. All forms
of life are constantly exposed to gravity and it can be assumed that
almost all organisms have developed sensors and respond in one way or
the other to the unidirectional acceleration force; this book shows us
some of these different ways.”
19
Braun M, Böhmer M, Häder D-P, Hemmersbach R, Palme K, editors.
Gravitational Biology I: Gravity Sensing and Graviorientation in Microorganisms and Plants.
Chaum: Springer International Publishing, 2018. 139 p.
https://link.springer.com/
20
Häder D-P, Braun M, Hemmersbach R.
Gravity sensing, graviorientation and microgravity.
In:
Braun M, Böhmer M, Häder D-P, Hemmersbach R, Palme K, eds.
Gravitational Biology I: Gravity Sensing and Graviorientation in
Microorganisms and Plants. Cham: Springer
International Publishing, 2018. p. 1-11.
https://link.springer.com/
Note:
Studies from parabolic flight and various spaceflights as well as ground-based simulation methods are discussed.
21
Hemmersbach R, Häder D-P, Braun M.
Methods for gravitational biology research.
In:
Braun M, Böhmer M, Häder D-P, Hemmersbach R, Palme K, eds.
Gravitational Biology I: Gravity Sensing and Graviorientation in
Microorganisms and Plants. Cham: Springer
International Publishing, 2018. p. 13-26.
https://link.springer.com/
22
Häder D-P, Hemmersbach R.
Gravitaxis in flagellates and ciliates.
In:
Braun M, Böhmer M, Häder D-P, Hemmersbach R, Palme K, eds.
Gravitational Biology I: Gravity Sensing and Graviorientation in
Microorganisms and Plants. Cham: Springer
International Publishing, 2018. p. 27-45.
https://link.springer.com/
Note: Ground-based and spaceflight studies are discussed.
23
Braun M.
Gravitropism in tip-growing rhizoids and protonemata of characean algae.
In:
Braun M, Böhmer M, Häder D-P, Hemmersbach R, Palme K, eds.
Gravitational Biology I: Gravity Sensing and Graviorientation in
Microorganisms and Plants. Cham: Springer
International Publishing, 2018. p. 47-65.
https://link.springer.com/
Note: Parabolic flight, sounding rocket, and Space Shuttle results.
24
Häder D-P.
Gravitropism in fungi, mosses and ferns.
In:
Braun M, Böhmer M, Häder D-P, Hemmersbach R, Palme K, eds.
Gravitational Biology I: Gravity Sensing and Graviorientation in
Microorganisms and Plants. Cham: Springer
International Publishing, 2018. p. 67-74.
https://link.springer.com/
25
Gadalla DS, Braun M, Böhmer M.
Gravitropism in higher plants: Cellular aspects.
In:
Braun M, Böhmer M, Häder D-P, Hemmersbach R, Palme K, eds.
Gravitational Biology I: Gravity Sensing and Graviorientation in
Microorganisms and Plants. Cham: Springer
International Publishing, 2018. p. 75-92.
https://link.springer.com/
Note: Parabolic flight and various spaceflight results are discussed as well as studies
that used clinostats, centrifuges, and drop towers.
26
Palme K, Teale W, Ditengou FA.
Gravitropism in higher plants: Molecular aspects.
In:
Braun M, Böhmer M, Häder D-P, Hemmersbach R, Palme K, eds.
Gravitational Biology I: Gravity Sensing and Graviorientation in
Microorganisms and Plants. Cham: Springer
International Publishing, 2018. p. 93-111.
https://link.springer.com/
27
Häder D-P, Braun M, Hemmersbach R.
Bioregenerative life support systems in space research.
In:
Braun M, Böhmer M, Häder D-P, Hemmersbach R, Palme K, eds.
Gravitational Biology I: Gravity Sensing and Graviorientation in
Microorganisms and Plants. Cham: Springer
International Publishing, 2018. p. 113-22.
https://link.springer.com/
