Status Report

NASA Spaceline Current Awareness List #797 4 May 2018 (Space Life Science Research Results)

By SpaceRef Editor
May 4, 2018
Filed under , , ,

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at
https://taskbook.nasaprs.com/Publication/spaceline.cfm.
Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,
SPACELINE@nasaprs.com.

Papers deriving from NASA support:

1

Meyer ME, Urban DL, Mulholland GW, Bryg V, Yuan ZG, Ruff GA, Cleary T, Yang J.

Evaluation of spacecraft smoke detector performance in the low-gravity environment.

Fire Saf J. 2018 Jun;98:74-81. Epub 2018 Apr 25.

https://www.sciencedirect.com/science/article/pii/S0379711216302181

Note:
ISS results.

Journal Impact Factor: 1.165

Funding: No funding cited. M.E. Meyer, D.L. Urban, and G.A. Ruff are affiliated with NASA
Glenn Research Center.

 

2

Uzer G, Bas G, Sen B, Xie Z, Birks S, Olcum M, McGrath C, Styner M, Rubin J.

Sun-mediated mechanical LINC between nucleus and cytoskeleton regulates betacatenin nuclear access.

J Biomech. 2018 Apr 12. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29691054

PI:
G. Uzer, NSBRI Postdoctoral Fellowship Program

Journal Impact Factor: 2.664

Funding:
“This
study was supported by NIH AR056655 (JR), AR066616 (JR), EB014351 (JR),
AR062097 (MS), P30DK056350 (MS), P20GM109095 (GU) and NSBRI PF04304
(GU) and NASA EPSCoR NNX15AK35A (GU).”

 

3

Ko
KA, Wang Y, Kotla S, Fujii Y, Vu HT, Venkatesulu BP, Thomas TN, Medina
JL, Gi YJ, Hada M, Grande-Allen J, Patel ZS, Milgrom SA, Krishnan S,
Fujiwara K, Abe JI.

Developing a reliable mouse model for cancer therapy-induced cardiovascular toxicity in cancer patients and survivors.

Front Cardiovasc Med. 2018 Apr 5;5:26.

https://www.ncbi.nlm.nih.gov/pubmed/29675417

PI: Z.S. Patel

Note:
This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “This work was partially supported by funding from the National Institutes of Health
to J-IA (HL- 130193, HL-123346, and HL-118462), and by NASA grant NASA 13-13OMNI2-0032 to ZP and JG-A.”

 

4

Almeida-Porada
G, Rodman C, Kuhlman B, Brudvik E, Moon J, George S, Guida P, Sajuthi
SP, Langefeld CD, Walker SJ, Wilson PF, Porada CD.

Exposure
of the bone marrow microenvironment to simulated solar and galactic
cosmic radiation induces biological bystander effects on human
hematopoiesis
.

Stem Cells Dev. 2018 Apr 26. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29698131

PI: C.D. Porada

Journal Impact Factor:
2.539

Funding:
“This
work was supported by grant no. NNX13AB67G from the National
Aeronautics and Space Administration (NASA) Human Research Program and
grant no. NNX17AE49G from the NASA Space
Biology Program.”

 

5

Raber J, Torres ERS, Akinyeke T, Lee J, Weber Boutros SJ, Turker MS, Kronenberg A.

Detrimental effects of helium ion irradiation on cognitive performance and cortical levels of MAP-2 in B6D2F1 mice.

Int J Mol Sci. 2018 Apr 20;19(4):E1247.

https://www.ncbi.nlm.nih.gov/pubmed/29677125

PI: A. Kronenberg

Note: This article may be obtained online without charge.

Journal Impact Factor:
3.226

Funding:
“This work was supported by NASA Grant NNJ16HP23I.”

 

6

Clément G, Reschke MF.

Relationship between motion sickness susceptibility and vestibulo-ocular reflex gain and phase.

J Vestib Res. 2018 Apr 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29689763

PI:
M.F. Reschke

Journal Impact Factor:
0.900

Funding:
“This study was supported by the National Aeronautics and Space Administration (NASA).”

__________________________________________________________________

 

 

Other papers of interest:

 

1

Baiocco
G, Giraudo M, Bocchini L, Barbieri S, Locantore I, Brussolo E, Giacosa
D, Meucci L, Steffenino S, Ballario A, Barresi B, Barresi R, Benassai M,
Ravagnolo L, Narici
L, Rizzo A, Carrubba E, Carubia F, Neri G, Crisconio M, Piccirillo S,
Valentini G, Barbero S, Giacci M, Lobascio C, Ottolenghi A.

A water-filled garment to protect astronauts during interplanetary missions tested on board the ISS.

Life Sci Space Res. 2018 Aug;18:1-11. Epub 2018 Apr 26.

https://www.sciencedirect.com/science/article/pii/S2214552417301335

Note: ISS results.

 

2

Wang L, Li Z, Tan C, Liu S, Zhang J, He S, Zou P, Liu W, Li Y.

Physiological effects of weightlessness: Countermeasure system development for a long-term Chinese manned spaceflight.

Front Med. 2018 Apr 25. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/29693211

 

3

Zhu H, Wang H, Yu C, Liu Z.

Effects of simulated weightlessness on thermal sweating of human body: An experimental study.

Indoor Built Environ. 2018 Apr 24.

http://journals.sagepub.com/doi/abs/10.1177/1420326X18770501

Note:
Bed rest study. This article may be obtained online without charge.

 

4

Mathieu E, Gupta N, Ahari A, Zhou X, Hanna J, Yucel YH.

Evidence for cerebrospinal fluid entry into the optic nerve via a glymphatic pathway.

Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4784-91.

https://www.ncbi.nlm.nih.gov/pubmed/28973323

Note:
See
also the comment by: Wostyn P, De Deyn PP. The “ocular glymphatic
system”: An important missing piece in the puzzle of optic disc edema in
astronauts? Invest Ophthalmol Vis Sci.
2018 Apr 1;59(5):2090-1. http://www.ncbi.nlm.nih.gov/pubmed/29677371. This article may be obtained online without charge.

 

5

Wostyn P, De Deyn PP.

The “ocular glymphatic system”: An important missing piece in the puzzle of optic disc edema in astronauts?

Invest Ophthalmol Vis Sci. 2018 Apr 1;59(5):2090-1.

https://www.ncbi.nlm.nih.gov/pubmed/29677371

Note: Comment on Mathieu E, Gupta N, Ahari A, Zhou X, Hanna J, Yucel YH. Evidence for cerebrospinal
fluid entry into the optic nerve via a glymphatic pathway. Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4784-91.
http://www.ncbi.nlm.nih.gov/pubmed/28973323. Cited above. This article may be obtained online without charge.

 

6

Kruck
B, Zimmermann EA, Damerow S, Figge C, Julien C, Wulstein D, Thiele T,
Martin M, Hamdy R, Reumann MK, Duda GN, Checa S, Willie BM.

Sclerostin-neutralizing antibody treatment enhances bone formation but does not rescue mechanically-induced delayed healing.

J Bone Miner Res. 2018 Apr 25. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29694687

 

7

Emoto K, Takao Y, Kuninaka H.

A preliminary study on radiation shielding using Martian magnetic anomalies.

Biol Sci Space. 2018 Apr 28;32:1-5.

https://www.jstage.jst.go.jp/article/bss/32/0/32_1/_article/-char/en

Note: This article may be obtained online without charge.

 

8

Kocher DC, Apostoaei AI, Hoffman FO, Trabalka JR.

Probability
distribution of dose and dose-rate effectiveness factor for use in
estimating risks of solid cancers from exposure to low-LET radiation
.

Health Phys. 2018 Jun;114(6):602-22. Epub 2018 Apr 23.

https://www.ncbi.nlm.nih.gov/pubmed/29697512

 

9

Gu Y.

Vestibular signals in primate cortex for self-motion perception.

Curr Opin Neurobiol. 2018 Apr 21;52:10-7. Review.

https://www.ncbi.nlm.nih.gov/pubmed/29694922

 

10

Jiang P, Turek FW.

The endogenous circadian clock programs animals to eat at certain times of the 24-hour day: What if we ignore the clock?

Physiol Behav. 2018 Apr 16. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/29673860  

 

11

Zhai B, Shang X, Fu J, Li F, Zhang T.

Rapamycin relieves anxious emotion and synaptic plasticity deficits induced by hindlimb unloading in mice.

Neurosci Lett. 2018 Apr 25;677:44-8.

https://www.ncbi.nlm.nih.gov/pubmed/29684531

Note: Hindlimb unloading study.

 

12

Nordberg RC, Bodle JC, Loboa EG.

Mechanical
stimulation of adipose-derived stem cells for functional tissue
engineering of the musculoskeletal system via cyclic hydrostatic
pressure, simulated microgravity,
and cyclic tensile strain
.

Methods Mol Biol. 2018;1773:215-30.

https://www.ncbi.nlm.nih.gov/pubmed/29687393

Note: A Rotary Cell Culture System was used.

 

13

Baba
AI, Rigó G, Ayaydin F, Rehman AU, Andrási N, Zsigmond L, Valkai I,
Urbancsok J, Vass I, Pasternak T, Palme K, Szabados L, Cséplő Á.

Functional analysis of the
Arabidopsis thaliana CDPK-related kinase family: AtCRK1 regulates responses to continuous light
.

Int J Mol Sci. 2018 Apr 25;19(5):E1282.

https://www.ncbi.nlm.nih.gov/pubmed/29693594

Note:
This article may be obtained online without charge.

 

14

Dupuy LX, Mimault M, Patko D, Ladmiral V, Ameduri B, MacDonald MP, Ptashnyk M.

Micromechanics of root development in soil.

Curr Opin Genet Dev. 2018 Apr 16;51:18-25. Review.

https://www.ncbi.nlm.nih.gov/pubmed/29674100

 

15

Kamal KY, Herranz R, van Loon J, Medina FJ.

Simulated microgravity, Mars gravity, and 2g hypergravity affect cell cycle regulation, ribosome biogenesis, and epigenetics in
Arabidopsis cell cultures
.

Sci Rep. 2018 Apr 23;8(1):6424.

https://www.ncbi.nlm.nih.gov/pubmed/29686401

Note: A Random Positioning Machine and a Large Diameter Centrifuge were used. This article
may be obtained online without charge.

 

16

Bornemann G, Waßer K, Hauslage J.

The influence of nitrogen concentration and precipitation on fertilizer production from urine using a trickling filter.

Life Sci Space Res. 2018 May 2. [Article in Press]

https://www.sciencedirect.com/science/article/pii/S2214552417301281

Note: This article may be obtained online without charge.

 

SpaceRef staff editor.