NASA Spaceline Current Awareness List #790 16 March 2018 (Space Life Science Research Results)
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Papers deriving from NASA support:
1
Carpentier WR, Charles JB, Shelhamer M, Hackler AS, Johnson TL, Domingo CMM, Sutton JP, Scott GBI, Wotring VE.
Biomedical findings from NASA’s Project Mercury: A case series.
npj Microgravity. 2018 Mar 13;4(1):6.
https://www.nature.com/
Note: Mercury results. This article may be obtained online without charge.
Journal Impact Factor:
Not available for this publication
Funding:
“V.E.W, G.B.I.S., T.L.J., C.M.M.D., A.S.H., and J.P.S. were supported
by NSBRI
(A.S.H. is now at USRA). J.B.C. is employed by NASA civil service;
W.R.C. is retired from NASA. M.S. was supported by NASA (detailed from
Johns Hopkins, his current employer.)”
2
Kassemi M, Griffin E, Thompson D.
Numerical assessment of CaOx renal calculi development in space using PBE coupled to urinary flow and species transport.
Int J Heat Mass Transf. 2018 Jun;121:1146-58. Epub 2018 Mar 7.
https://www.sciencedirect.com/
PI: M. Kassemi
Journal Impact Factor: 3.458
Funding:
“We gratefully acknowledge the funding support from the Exploration Medical Capabilities Element of NASA’s Human Research.”
3
Cowings PS, Toscano WB, Reschke MF, Tsehay A.
Psychophysiological assessment and correction of spatial disorientation during simulated Orion spacecraft re-entry.
Int J Psychophysiol. 2018 Mar 2. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PI: P.S. Cowings
Journal Impact Factor: 2.582
Funding:
“This
work was supported by the National Aeronautics and Space Administration
(NASA) (13-13OMNI2-0064), Human Research Program, Human Health
Countermeasures element, and was conducted
at NASA Ames Research Center.”
______________________________
Other papers of interest:
1
Kuzichkin DS, Markin AA, Juravlyova OA, Krivitsina ZA, Vostrikova LV, Zabolotskaya IV.
Reference values of the hemostasis system indices in cosmonauts.
Fiziol Cheloveka. 2017 Jan;43(1):126-9.
https://www.ncbi.nlm.nih.gov/
Note: ISS results. An English translation of this article is available at:
https://link.springer.com/
2
Uchida
T, Sakashita Y, Kitahata K, Yamashita Y, Tomida C, Kimori Y, Komatsu A,
Hirasaka K, Ohno A, Nakao R, Higashitani A, Higashibata A, Ishioka N,
Shimazu T, Kobayashi
T, Okumura Y, Choi I, Oarada M, Mills EM, Teshima-Kondo S, Takeda S,
Tanaka E, Tanaka K, Sokabe M, Nikawa T.
Reactive
oxygen species up-regulate expression of muscle atrophy-associated
ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells.
Am J Physiol Cell Physiol. 2018 Mar 7. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: ISS results. The study was conducted as part of JAXA’s MyoLab project, “Cbl-Mediated
Protein Ubiquitination Downregulates the Response of Skeletal Muscle Cells to Growth Factors in Space.”
3
Di Rienzo M, Vaini E, Lombardi P.
Development
of a smart garment for the assessment of cardiac mechanical performance
and other vital signs during sleep in microgravity.
Sens Actuators A-Phys. 2018 Mar 1. [Article in Press]
http://www.sciencedirect.com/
Note:
ISS results.
4
Friedrich U, Stang K.
[Parabolic flights for multidisciplinary microgravity research – the DLR program from 1999 to 2017].
Flugmedizin Tropenmedizin Reisemedizin. 2018 Feb;25(1):13-8. German.
https://www.thieme-connect.
Note: Parabolic flight results from the German Aerospace Centre DLR parabolic flight campaigns.
5
Pastushkova
LH, Kashirina DN, Brzhozovsky AG, Ivanisenko VA, Tiys ES, Kononikhin
AS, Starodubtseva NL, Nikolaev EN, Binder H, Larina IM.
Effect
of different levels of salt consumption on urine protein composition
during 105-day isolation analyzed with the use of opoSOM software.
Fiziol Cheloveka. 2017 Jan;43(1):89-96.
https://www.ncbi.nlm.nih.gov/
Note:
Mars-500 Program results. An English translation of this article is available at:
https://link.springer.com/
6
Grimm D, Egli M, Krüger M, Riwaldt S, Corydon TJ, Kopp S, Wehland M, Wise P, Infanger M, Mann V, Sundaresan A.
Tissue engineering under microgravity conditions – Use of stem cells and specialized cells.
Stem Cells Dev. 2018 Mar 6. [Article in Press] Review.
https://www.liebertpub.com/
Note: The discussion focuses on random positioning machines, clinostats, and rotating wall
vessels.
7
Stancic A, Jankovic A, Korac A, Cirovic D, Otasevic V, Storey KB, Korac B.
A lesson from the oxidative metabolism of hibernator heart: Possible strategy for cardioprotection.
Comp Biochem Physiol B Biochem Mol Biol. 2018 Mar 5;219-220:1-9.
https://www.ncbi.nlm.nih.gov/
8
Mazzoli V, Gottwald LM, Peper ES, Froeling M, Coolen BF, Verdonschot N, Sprengers AM, van Ooij P, Strijkers GJ, Nederveen AJ.
Accelerated 4D phase contrast MRI in skeletal muscle contraction.
Magn Reson Med. 2018 Mar 5. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
9
Piasecki M, Ireland A, Piasecki J, Stashuk DW, Swiecicka A, Rutter MK, Jones DA, McPhee JS.
Failure
to expand the motor unit size to compensate for declining motor unit
numbers distinguishes sarcopenic from non-sarcopenic older men.
J Physiol. 2018 Mar 11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
10
Zhang ZK, Li J, Guan D, Liang C, Zhuo Z, Liu J, Lu A, Zhang G, Zhang BT.
A newly identified lncRNA MAR1 acts as a miR-487b sponge to promote skeletal muscle differentiation and regeneration.
J Cachexia Sarcopenia Muscle. 2018 Mar 7. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study. This article may be obtained online without charge.
11
George EL, Truesdell SL, York SL, Saunders MM.
Lab-on-a-chip platforms for quantification of multicellular interactions in bone remodeling.
Exp Cell Res. 2018 Feb 28. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
12
Lodberg A, Eijken M, van der Eerden BCJ, Okkels MW, Thomsen JS, Brüel A.
A
soluble activin type IIA receptor mitigates the loss of femoral neck
bone strength and cancellous bone mass in a mouse model of disuse
osteopenia.
Bone. 2018 Feb 28;110:326-34.
https://www.ncbi.nlm.nih.gov/
Note:
Hindlimb immobilization was accomplished via botulinum toxin A.
13
Cook JA, Naz S, Anver MR, Sowers AL, Fabre K, Krishna MC, Mitchell JB.
Cancer incidence in C3H mice protected from lethal total-body radiation after amifostine.
Radiat Res. 2018 Mar 12. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
14
Lamkowski
A, Kreitlow M, Radunz J, Willenbockel M, Sabath F, Schuhn W, Stiemer M,
Fichte LO, Dudzinski M, Böhmelt S, Ullmann R, Majewski M, Franchini V,
Ede S, Rump A, Port
M, Abend M.
Gene expression analysis in human peripheral blood cells after 900 MHz RF-EMF short-term exposure.
Radiat Res. 2018 Mar 6. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
15
Mohan R, Held KD, Story MD, Grosshans D, Capala J.
Proceedings of the National Cancer Institute Workshop on Charged Particle Radiobiology.
Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):816-31.
https://www.ncbi.nlm.nih.gov/
16
Vyšín L, Burian T, Ukraintsev E, Davidková M, Grisham ME, Heinbuch S, Rocca JJ, Juha L.
Dose-rate effects in breaking DNA strands by short pulses of extreme ultraviolet radiation.
Radiat Res. 2018 Mar 5. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
17
Han CH, Zhang PX, Xu WG, Li RP, Xu JJ, Liu WW.
Polarization of macrophages in the blood after decompression in mice.
Med Gas Res. 2017 Oct-Dec;7(4):236-40.
https://www.ncbi.nlm.nih.gov/
Note:
This article may be obtained online without charge.
18
Zou Y, Zhang L, Li L, Ma H, Liu K.
Running experimental research of a wire driven astronaut rehabilitative training robot.
IEEE Access. 2018 Feb 27. [Article in Press]
http://ieeexplore.ieee.org/
Note:
From the abstract: “…this paper proposes a wire driven astronaut
rehabilitative
training robot (ART) that simulates the characteristics of the gravity
environment and load force on the astronauts.” This article may be
obtained online without charge.
19
Scofield DC, Rytlewski JD, Childress P, Shah K, Tucker A, Khan F, Peveler J, Li D, McKinley TO, Chu TG, Hickman DL, Kacena MA.
Development
of a step-down method for altering male C57BL/6 mouse housing density
and hierarchical structure: Preparations for spaceflight studies.
Life Sci Space Res. 2018 Mar 7. [Article in Press]
https://www.sciencedirect.com/
20
Thornhill SG, Kumar M.
Biological filters and their use in potable water filtration systems in spaceflight conditions.
Life Sci Space Res. 2018 Mar 6. [Article in Press]
https://www.sciencedirect.com/
