NASA Spaceline Current Awareness List #760 4 August 2017 (Space Life Science Research Results))
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Papers deriving from NASA support:
1
Rettig TA, Ward C, Pecaut MJ, Chapes SK.
Validation of methods to assess the immunoglobulin gene repertoire in tissues obtained from mice on the International Space Station.
Gravit Space Res. 2017 Jul;5(1):2-23.
http://
PIs: M.J. Pecaut, S.K. Chapes
Note: ISS results. GeneLab: “The MiSeq® workflow described above was modified to analyze mouse liver transcriptomic data from the Rodent Research 1 (RR1) NASA validation flight provided by the NASA GeneLab program (https://genelab-data.ndc.
Journal Impact Factor: Not available for this journal
Funding: “This work was supported by NASA grants NNX13AN34G and NNX15AB45G, NIH grant GM103418, the Molecular Biology Core supported by the College of Veterinary Medicine at Kansas State University, and the Kansas State University Johnson Cancer Center.”
2
Massa GD, Newsham G, Hummerick ME, Morrow RC, Wheeler RM.
Plant pillow preparation for the Veggie plant growth system on the International SpaceStation.
Gravit Space Res. 2017 Jul;5(1):24-34.
http://
PI: G.D. Massa
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This work was supported by NASA’s Division of Space Life and Physical Sciences Research and Applications.”
3
Frippiat JP, Crucian BE, de Quervain DJ, Grimm D, Montano N, Praun S, Roozendaal B, Schelling G, Thiel M, Ullrich O, Choukèr A.
Towards human exploration of space: The THESEUS review series on immunology research priorities.
npj Microgravity. 2016 Dec;2:16040. Review.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “This review is a product of the Theseus Project: Towards Human Exploration of Space: a European Strategy of the European Science Foundation and was supported by European Community’s 7th Framework Programme (FP7/2007–2013) under grant agreement #242482. We also thank the French (CNES), the German (DLR), the Italian (ASI), the Russian (IBMP, Rocosmos) and the American (NASA) space agencies for their support.” B. E. Crucian is affiliated with NASA Johnson Space Center.
4
Mao XW, Nishiyama NC, Campbell-Beachler M, Gifford P, Haynes KE, Gridley DS, Pecaut MJ.
Role of NADPH oxidase as a mediator of oxidative damage in low-dose irradiated and hindlimb-unloaded mice.
Radiat Res. 2017 Aug 1. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study.
PI: X.W. Mao
Journal Impact Factor: 2.539
Funding: “This study was supported by National Aeronautics and Space Administration (NASA grant no. NNX13AL97G) and the Department of Basic Sciences, Loma Linda University.”
5
Werner E, Wang Y, Doetsch PW.
A single exposure to low- or high-LET radiation induces persistent genomic damage in mouse epithelial cells in vitro and in lung tissue.
Radiat Res. 2017 Jul 28. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
PIs: Y. Wang/P.W. Doetsch/NSCOR
Journal Impact Factor: 2.539
Funding: “This research project was supported in part by the Emory University Integrated Cellular Imaging Microscopy Core of the Winship Cancer Institute comprehensive cancer center grant, no. P30CA138292. This work was funded by NASA NSCOR grant no. NNX11AC30G and DoD grant no. W81XWH-17-1-0187 to PD and NNX11AC30G to YW.”
6
Nielsen C, Rahman A, Rehman AU, Walsh MK, Miller CD.
Food waste conversion to microbial polyhydroxyalkanoates.
Microb Biotechnol. 2017 Jul 24. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.513
Funding: “Asad Ur Rehman was supported by a U.S. Fulbright Scholarship.” A. Rahman is affiliated with NASA Ames Research Center.
7
Smith DJ, Sowa MB.
Ballooning for biologists: Mission essentials for flying life science experiments to near space.
Gravit Space Res. 2017 Jul;5(1):52-73. Review.
http://
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: No funding cited. D.J. Smith and M.B. Sowa are affiliated with NASA Ames Research Center.
______________________________
Other papers of interest:
1
Zhao L, Rui Q, Wang D.
Molecular basis for oxidative stress induced by simulated microgravity in nematodeCaenorhabditis elegans.
Sci Total Environ. 2017 Dec;607-608:1381-90. Epub 2017 Jul 19.
https://www.ncbi.nlm.nih.gov/
Note: A Rotary Cell Culture System was used.
2
Arun RP, Sivanesan D, Vidyasekar P, Verma RS.
PTEN/FOXO3/AKT pathway regulates cell death and mediates morphogenetic differentiation of colorectal cancer cells under simulated microgravity.
Sci Rep. 2017 Jul 20;7(1):5952.
https://www.ncbi.nlm.nih.gov/
Note: A Rotational Cell Culture System was used. This article may be obtained online without charge.
3
Ogoh S, Hirasawa A, de Abreu S, Denise P, Normand H.
Internal carotid, external carotid and vertebral artery blood flow responses to a 3-day of head-out dry immersion.
Exp Physiol. 2017 Jul 26. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
Note: Dry immersion was used to simulate weightlessness.
4
Lautridou J, Buzzacott P, Belhomme M, Dugrenot E, Lafère P, Balestra C, Guerrero F.
Evidence of heritable determinants of decompression sickness in rats.
Med Sci Sports Exerc. 2017 Jul 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
5
Matsumoto T, Ono T, Ishikura H, Aihara K, Sato Y, Tasaka A, Umei N, Tsumiyama W, Oki S.
Effects of joint immobilization and hindlimb unloading on collagen fibers of soleus muscles in rats.
J Phys Ther Sci. 2017 Jul;29(7):1192-5.
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading was used. Joint fixation was accomplished with non-elastic tape. This article may be obtained online without charge.
6
Perry RA, Martin JL, Vickers SD, Cesarz GM, Bai L, Selimovic EA, Muntis F, Parmar PJ, Caruso JF.
Lower leg anthropometry as a correlate to performance and metabolism from dynamic exercise.
Gravit Space Res. 2017 Jul;5(1):41-51.
http://
Note: This article may be obtained online without charge.
7
Takemura A, Roy RR, Yoshihara I, Ishihara A.
Unloading-induced atrophy and decreased oxidative capacity of the soleus muscle in rats are reversed by pre- and postconditioning with mild hyperbaric oxygen.
Physiol Rep. 2017 Jul;5(14).
https://www.ncbi.nlm.nih.gov/
Note: Hindlimb unloading study. This article may be obtained online without charge.
8
Johannesdottir F, Thrall E, Muller J, Keaveny TM, Kopperdahl DL, Bouxsein ML.
Comparison of non-invasive assessments of strength of the proximal femur.
Bone. 2017 Jul 21. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
9
Scheuren A, Wehrle E, Flohr F, Müller R.
Bone mechanobiology in mice: toward single-cell in vivo mechanomics.
Biomech Model Mechanobiol. 2017 Jul 22. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
10
Swanson C, Shea SA, Wolfe P, Markwardt S, Cain SW, Munch M, Czeisler CA, Orwoll ES, Buxton OM.
24-hour profile of serum sclerostin and its association with bone biomarkers in men.
Osteoporos Int. 2017 Jul 26. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
11
Miller AC, Rivas R, McMahon R, Miller K, Tesoro L, Villa V, Yanushkevich D, Lison P.
Radiation protection and mitigation potential of phenylbutyrate: Delivered via oral administration.
Int J Radiat Biol. 2017 Jul 27:1-13. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
12
Tharmalingam S, Sreetharan S, Kulesza AV, Boreham DR, Tai TC.
Low-dose ionizing radiation exposure, oxidative stress and epigenetic programing of health and disease.
Radiat Res. 2017 Jul 28. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
13
Lim K, Wang W, Merfeld DM.
Unbounded evidence accumulation characterizes subjective visual vertical (SVV) forced-choice perceptual choice and confidence.
J Neurophysiol. 2017 Jul 26:jn.00318.2017. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
14
Lacerenza CN, Reyes DL, Marlow SL, Joseph DL, Salas E.
Leadership training design, delivery, and implementation: A meta-analysis.
J Appl Psychol. 2017 Jul 27. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
15
Reinerman-Jones L, Barber DJ, Szalma JL, Hancock PA.
Human interaction with robotic systems: Performance and workload evaluations.
Ergonomics. 2017 Jul 26:1-18. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/
16
Kovacs GTA, Shadden M.
Analysis of age as a factor in NASA astronaut selection and career landmarks.
PLoS One. 2017 Jul 27;12(7):e0181381.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
17
Lüthen C, Jaschinski N.
Pressure suits for suborbital spaceflight – mandatory or not?
J Space Safety Eng. 2017 Jul 26. [Article in Press]
http://www.sciencedirect.com/
18
Pu Y, Luo X, Bassham DC.
TOR-dependent and -independent pathways regulate autophagy in Arabidopsis thaliana.
Front Plant Sci. 2017 Jul 11;8:1204.
https://www.ncbi.nlm.nih.gov/
Note: This article may be obtained online without charge.
19
Wang P, Mugume Y, Bassham DC.
New advances in autophagy in plants: Regulation, selectivity and function.
Semin Cell Dev Biol. 2017 Jul 20. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/
