Status Report

NASA Spaceline Current Awareness List #667 2 October 2015

By SpaceRef Editor

October 2, 2015

Filed under ISS, Spaceline, Spaceline Current Awareness, US

Papers deriving from NASA support:

Hryciw G, Grygoryev D, Lasarev M, Ohlrich A, Dan C, Madhira R, Eckelmann B, Gauny S, Kronenberg A, Turker MS.

Accelerated Ti ions induce autosomal mutations in mouse kidney epithelium at low dose and fluence.

Radiat Res. 2015. Epub 2015 Sep 23.

http://www.ncbi.nlm.nih.gov/pubmed/26397174

PIs: A. Kronenberg, M.S. Turker

Journal Impact Factor: 2.911

Funding: “This work was supported by NASA grants (nos. NNJ12HB88I and NNJ13ZSA001N), a Murdock Scholar Fellowship to Gwen Hryciw and an Oregon Institute of Occupational Health Sciences summer fellowship to Bradley Eckelmann.”

Rithidech K, Tungjai M, Jangiam W, Honikel L, Gordon C, Lai X, Witzmann F.

Proteomic profiling of hematopoietic stem/progenitor cells after a whole body exposure of CBA/CaJ mice to titanium (48Ti) ions.

Proteomes. 2015 Sep;3(3):132.

http://www.mdpi.com/2227-7382/3/3/132

PI: K.N. Rithidech

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “This research was supported in part by the National Aeronautics and Space Administration (NASA) Grant # NNX11AK91G and the Department of Pathology, Stony Brook University, Stony Brook, NY, USA.”

Rithidech KN, Honikel LM, Reungpathanaphong P, Tungjai M, Jangiam W, Whorton EB.

Late-occurring chromosome aberrations and global DNA methylation in hematopoietic stem/progenitor cells of CBA/CaJ mice exposed to silicon (Si) ions.

Mutat Res. 2015 Sep 12;781:22-31. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26398320

PI: K.N. Rithidech

Journal Impact Factor: 3.680

Funding: “This research was supported by the National Aeronautics and Space Administration (NASA) Grant # NNX11AK91G.”

Lee CL, Castle KD, Moding EJ, Blum JM, Williams N, Luo L, Ma Y, Borst LB, Kim Y, Kirsch DG.

Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma.

Nat Commun. 2015 Sep 24;6:8477.

http://www.ncbi.nlm.nih.gov/pubmed/26399548

PI: D.G. Kirsch/NSCOR

Note: This article may be obtained online without charge.

Journal Impact Factor: 11.470

Funding: “These studies were supported by NIAID R01 AI080488 (D.G.K.), NASA NSCOR NNX11AC60G (D.G.K.) and partially by the P30-CA14236 Cancer Center Core grant.”

Koppelmans V, Mulavara AP, Yuan P, Cassady KE, Cooke KA, Wood SJ, Reuter-Lorenz PA, De Dios YE, Stepanyan V, Szecsy DL, Gadd NE, Kofman I, Scott JM, Downs ME, Bloomberg JJ, Ploutz-Snyder L, Seidler RD.

Exercise as potential countermeasure for the effects of 70 days of bed rest on cognitive and sensorimotor performance.

Front Syst Neurosci. 2015 Sep 3;9:121.

http://www.ncbi.nlm.nih.gov/pubmed/26388746

PIs: R.D. Seidler; L. Ploutz-Snyder; V. Koppelmans, NSBRI Postdoctoral Fellowship Program

Note: Bed rest study. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “This work is supported by the National Space Biomedical Research Institute (NASA NCC 9-58, MA02701, and PF04101), grants from the National Aeronautics and Space Administration (NASA; NNX11AR02G) and NASA Flight Analogs Project, National Institutes of Health, and National Center for Advancing Translational Sciences, 1UL1RR029876-01.”

Loureno TF, Serra TS, Cordeiro AM, Swanson SJ, Gilroy S, Saibo NJ, Oliveira MM.

The rice E3 ubiquitin ligase OsHOS1 modulates the expression of OsRMC, a gene involved in root mechano-sensing, through the interaction with two ERF transcription factors.

Plant Physiol. 2015 Sep 17. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26381316

PI: S. Gilroy

Journal Impact Factor: 6.841

Funding: “This work was supported by the Fundao para a Cincia e a Tecnologia (FCT) through the projects POCI/BIA-BCM/56063/2004, PTDC/BIA_BCM/099836/2008, and research unit GREEN-iT “Bioresources for Sustainability” (UID/Multi/04551/2013), and fellowships SFRH/BPD/102872/2014 (TFL), SFRH/BD/31011/2006 (TSS), and SFRH/BD/74946/2010 (AMC). NJMS was supported by Programa Cincia 2007 and FCT Investigator 2012, financed by POPH (QREN). SG was supported by NSF (IOS-11213800) and NASA (NNX12AK79G).”

___________________________________________________

Other papers of interest:

Chatani M, Mantoku A, Takeyama K, Abduweli D, Sugamori Y, Aoki K, Ohya K, Suzuki H, Uchida S, Sakimura T, Kono Y, Tanigaki F, Shirakawa M, Takano Y, Kudo A.

Microgravity promotes osteoclast activity in medaka fish reared at the International Space Station.

Sci Rep. 2015 Sep 21;5:14172.

http://www.ncbi.nlm.nih.gov/pubmed/26387549

Note: ISS results. This article may be obtained online without charge.

Proshchina AE, Krivova YS, Saveliev SC.

Pancreas of C57 black mice after long-term space flight (Bion-M 1 space mission).

Life Sci Space Res. 2015 Sep 30. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552415000796

Note: Bion-M1 results.

Grigorenko DY, Sapin MR, Yerofeyeva LM.

[Characteristics of the reactions of the spleen lymphoid structures in mice in a terrestrial experiment and after a prolonged spaceflight].

Morfologiia. 2015;147(3):22-6. Russian.

http://www.ncbi.nlm.nih.gov/pubmed/26390542

Note: Space flight and ground study results; the particular flight and method of microgravity simulation are not specified in the abstract.

Tipton MJ.

Environmental extremes: Origins, consequences and amelioration in humans.

Exp Physiol. 2015 Sep 22. [Epub ahead of print]. Review

http://www.ncbi.nlm.nih.gov/pubmed/26391095

Note: This article is the text of the GL Brown Lecture, given in memory of the distinguished physiologist Sir George Lindor Brown (1903-1971). It is aimed at a younger audience with a view to stimulating an interest in physiology. Extreme environments discussed include: microgravity, hypobaria, hyperbaria, heat, cold air, and cold water. This article may be obtained online without charge.

Waha JE, Goswami N, Schlagenhauf A, Leschnik B, Koestenberger M, Reibnegger G, Roller RE, Hinghofer-Szalkay H, Cvirn G.

Effects of exercise and nutrition on the coagulation system during bedrest immobilization.

Medicine (Baltimore). 2015 Sep;94(38):e1555.

http://www.ncbi.nlm.nih.gov/pubmed/26402815

Note: Bed rest study.

Rabinovitch A, Friedman M, Braunstein D, Biton Y, Aviram I.

The baroreflex mechanism revisited.

Bull Math Biol. 2015 Sep 22. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26394627

Sayk F, Wobbe I, Twesten C, Meusel M, Wellhner P, Derad I, Dodt C.

Prolonged blood pressure elevation following continuous infusion of angiotensin-II – A baroreflex study in healthy humans.

Am J Physiol Regul Integr Comp Physiol. 2015 Sep 23:ajpregu.00111.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26400183

Lee I, Httemann M, Malek MH.

(-)-Epicatechin attenuates degradation of mouse oxidative muscle following hindlimb suspension.

J Strength Cond Res. 2015 Sep 12. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26382133

Note: Hindlimb unloading study.

Hashimoto R, Sakai A, Murayama M, Ochi A, Abe T, Hirasaka K, Ohno A, Teshima-Kondo S, Yanagawa H, Yasui N, Inatsugi M, Doi D, Takeda M, Mukai R, Terao J, Nikawa T.

Effects of dietary soy protein on skeletal muscle volume and strength in humans with various physical activities.

J Med Invest. 2015 Aug;62(3-4):177-83.

http://www.ncbi.nlm.nih.gov/pubmed/26399344

Note: This article may be obtained online without charge.

Xie P, Tang Z, Qing F, Chen X, Zhu X, Fan Y, Yang X, Zhang X.

Bone mineral density, microarchitectural and mechanical alterations of osteoporotic rat bone under long-term whole-body vibration therapy.

J Mech Behav Biomed Mater. 2015 Sep 8;53:341-9. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26398779

Belley MD, Ashcraft KA, Lee CT, Cornwall-Brady MR, Chen JJ, Gunasingha R, Burkhart M, Dewhirst M, Yoshizumi TT, Down JD.

Microdosimetric and biological effects of photon irradiation at different energies in bone marrow.

Radiat Res. 2015 Sep 24. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26401594

Du YR, Pan D, Chen YX, Xue G, Ren ZX, Li XM, Zhang SC, Hu BR.

Irradiation response of adipose-derived stem cells under three-dimensional culture condition.

Biomed Environ Sci. 2015 Aug;28(8):549-57.

http://www.ncbi.nlm.nih.gov/pubmed/26383593

Note: This article may be obtained online without charge.

Hamaguchi Y, Tahara Y, Kuroda H, Haraguchi A, Shibata S.

Entrainment of mouse peripheral circadian clocks to <24 h feeding/fasting cycles under 24 h light/dark conditions.

Sci Rep. 2015 Sep 23;5:14207.

http://www.ncbi.nlm.nih.gov/pubmed/26395309

Note: This article may be obtained online without charge.

Lei Q, Lee E, Keerthisinghe S, Lai L, Li M, Lucas JR, Wen X, Ren X, Sack FD.

The FOUR LIPS and MYB88 transcription factor genes are widely expressed in Arabidopsis thaliana during development.

Am J Bot. 2015 Sep;102(9):1521-8. Epub 2015 Sep 7.

http://www.ncbi.nlm.nih.gov/pubmed/26391711

Note: Fred Sack, a former Space Biology Flight PI, passed away in June.

Pesacreta TC.

F-actin distribution in root primary tissues of several seed plant species.

Am J Bot. 2015 Sep;102(9):1422-33. Epub 2015 Sep 7.

http://www.ncbi.nlm.nih.gov/pubmed/26391707

Brazin KN, Mallis RJ, Das DK, Feng Y, Hwang W, Wang JH, Wagner G, Lang MJ, Reinherz EL.

Structural features of the TCR mechanotransduction apparatus that promote pMHC discrimination.

Front Immunol. 2015 Sep 3;6:441.

http://www.ncbi.nlm.nih.gov/pubmed/26388869

Note: This article may be obtained online without charge.

SpaceRef Editor

SpaceRef staff editor.

Follow on Twitter