Status Report

NASA SPACELINE Current Awareness List #666 25 September 2015

By SpaceRef Editor
September 25, 2015
Filed under , , ,

Papers deriving from NASA support:



Crucian B, Stowe RP, Mehta S, Quiriarte H, Pierson D, Sams C.

Alterations in adaptive immunity persist during long-duration spaceflight.

npj Microgravity. 2015;1:15013. Epub 2015 Sep 3.

PI: C. Sams

Note: ISS results.

Journal Impact Factor: Not available for this journal

Funding: “This work was supported by National Aeronautics and Space Administration.” From Contributions: “…CS [Clarence Sams]: principal investigator.”



Johnson CM, Subramanian A, Edelmann RE, Kiss JZ.

Morphometric analyses of petioles of seedlings grown in a spaceflight experiment.

J Plant Res. 2015 Sep 16. [Epub ahead of print]

PI: J.Z. Kiss

Note: STS-131 results.

Journal Impact Factor: 1.823

Funding: “Financial support for this project was provided by NASA though grant NNX10AF44G.”



Fiuza-Luces C, Simpson RJ, Ramirez M, Lucia A, Berger NA.

Physical function and quality of life in patients with chronic GvHD: A summary of preclinical and clinical studies and a call for exercise intervention trials in patients.

Bone Marrow Transplant. 2015 Sep 14. [Epub ahead of print] Review.

PI: R.J. Simpson

Journal Impact Factor: 3.570

Funding: “This work was supported, in part, by PI07/0907 and PI10/02802 to MR; PI12/0094, Instituto de Salud Carlos III (Spain) and P2015UEM49 Universidad Europea and co-funded by Fondo de Investigaciones Sanitarias and FEDER (Spain) to AL; Sara Borell PhD Contract CD14/00005, Institute de Salud Carlos III (Spain) to CF-L; USA NASA Grant NNJ1 0ZSA003N to RS; and Ellison Medical Foundation and USA NIH Grants P50 CA150964 and U54CA163060 to NB.”



Romero LM, Platts SH, Schoech SJ, Wada H, Crespi E, Martin LB, Buck CL.

Understanding stress in the healthy animal – Potential paths for progress.

Stress. 2015 Sep 12:1-7. [Epub ahead of print]

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.715

Funding: “The workshop was funded by NSF IOS-1403615 to LMR and funding from NASA.” S.H. Platts is at NASA Johnson Space Center.



Gurzadyan VG, Yan H, Vlahovic G, Kashin A, Killela P, Reitman Z, Sargsyan S, Yegorian G, Milledge G, Vlahovic B.

Detecting somatic mutations in genomic sequences by means of Kolmogorov-Arnold analysis.

R Soc Open Sci. 2015 Aug;2(8):150143.

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “V.G.G., A.K., S.S., G.Y., G.M. and B.V. are funded by NSF (HRD-0833184) and NASA (NNX09AV07A). H.Y., G.V., P.K., G.V. and Z.R. are funded by The V Foundation and an Accelerate Brain Cancer Cure Foundation grant, a Voices Against Brain Cancer Foundation grant, a Pediatric Brain Tumor Foundation Institute grant, a James S. McDonnell Foundation grant, American Cancer Society Research Scholar Award RSG-10-126-01-CCE and National Cancer Institute grant no. 5R01-CA140316.”



Elkin SR, Bendris N, Reis C, Zhou Y, Xie Y, Huffman KE, Minna JD, Schmid SL.

A systematic analysis reveals heterogeneous changes in the endocytic activities of cancer cells.

Cancer Res. 2015 Sep 10. [Epub ahead of print]

PIs: J.D. Minna/Y. Xie/NSCOR

Journal Impact Factor: 9.329

Funding: “This work was supported by NIH grant R01GM042455 and R01GM073165 to SLS, NIH grant RO1CA15230 and Cancer Prevention Research Institute of Texas Award RP101251 to YX, as well as Lung Cancer SPORE P50CA70907 and NASA NSCOR NNX11AC54G to JDM. SRE was supported by an HHMI Med into Grad Grant (Grant#56006776) to the Mechanisms of Disease and Translational Science Track supported by NIH T32 (Grant#1T32GM10977601) and the Pharmacological Sciences Training Grant (GM00706240).”



Philbrick KA, Turner RT, Branscum AJ, Wong CP, Iwaniec UT.

Paradoxical effects of partial leptin deficiency on bone in growing female mice.

Anat Rec (Hoboken). 2015 Sep 15. [Epub ahead of print]

PI: R.T. Turner

Journal Impact Factor: 1.542

Funding: “Grant Sponsors: NIH, AR 060913; NASA, NNX12AL24G; and USDA, 38420-17804.”



Deymier-Black AC, Pasteris JD, Genin GM, Thomopoulos S.

Allometry of the tendon enthesis: Mechanisms of load transfer between tendon and bone.

J Biomech Eng. 2015 Sep 10. [Epub ahead of print]

PI: A.C. Deymier-Black, NSBRI Postdoctoral Fellowship Program

Journal Impact Factor: 1.780

Funding: “This project was funded by National Institute of Health (NIH) R01 EB016422 and R01 AR057836. Dr. Deymier-Black was funded in part by the National Space Biomedical Research Institute (NSBRI) NSBRI-RFA-13-01 Postdoctoral First Fellow Award.”



Other papers of interest:



Wakabayashi K, Soga K, Hoson T, Kotake T, Yamazaki T, Higashibata A, Ishioka N, Shimazu T, Fukui K, Osada I, Kasahara H, Kamada M.

Suppression of hydroxycinnamate network formation in cell walls of rice shoots grown under microgravity conditions in space.

PLoS One. 2015 Sep 17;10(9):e0137992.

Note: ISS results. From the Acknowledgements: “The Ferulate experiment was close collaboration between the Japan Aerospace Exploration Agency (JAXA), the National Aeronautics and Space Administration (NASA), and related organizations and companies.” This article may be obtained online without charge.



Wang Y, Javed I, Liu Y, Su R, Lu S, Peng G, Zhang Y, Qing H, Deng Y.

Effects of simulated microgravity on the expression of presynaptic proteins distorting the GABA/glutamate equilibrium – A proteomics approach.

Proteomics. 2015 Sep 11. [Epub ahead of print]

Note: Hindlimb unloading study.



Jagodnik KM, Blana D, van den Bogert AJ, Kirsch RF.

An optimized proportional-derivative controller for the human upper extremity with gravity.

J Biomech. 2015 Aug 29. [Epub ahead of print]



Hiramatsu Y, Kimura D, Kadota K, Ito T, Kinoshita H.

Control of precision grip force in lifting and holding of low-mass objects.

PLoS One. 2015 Sep 16;10(9):e0138506.

Note: This article may be obtained online without charge.



Schwartz C, Ballinger MA, Andrews MT.

Melatonin receptor signaling contributes to neuroprotection upon arousal from torpor in thirteen-lined ground squirrels.

Am J Physiol Regul Integr Comp Physiol. 2015 Sep 9:ajpregu.00292.2015. [Epub ahead of print]



van Helmond N, Johnson BD, Curry TB, Cap AP, Convertino VA, Joyner MJ.

Coagulation changes during lower body negative pressure and blood loss in humans.

Am J Physiol Heart Circ Physiol. 2015 Sep 14:ajpheart.00435.2015. [Epub ahead of print]



Trotter B, Otte KA, Schoppmann K, Hemmersbach R, Fröhlich T, Arnold GJ, Laforsch C.

The influence of simulated microgravity on the proteome of Daphnia magna.

npj Microgravity. 2015;1:15016. Epub 2015 Sep 24.

Note: A 2D clinostat was used.



Brocca L, Longa E, Cannavino J, Seynnes O, de Vito G, McPhee J, Narici M, Pellegrino MA, Bottinelli R.

Human skeletal muscle fibre contractile properties and proteomic profile: Adaptations to 3-week unilateral lower limb suspension and active recovery.

J Physiol. 2015 Sep 15. [Epub ahead of print]

Note: Unilateral lower limb suspension was used.



Beharry AW, Judge AR.

Differential expression of HDAC and HAT genes in atrophying skeletal muscle.

Muscle Nerve. 2015 Sep 15. [Epub ahead of print]



Fallahi M, Motamedzade M, Heidarimoghadam R, Soltanian AR, Miyake S.

Effects of mental workload on physiological and subjective responses during traffic density monitoring: A field study.

Appl Ergon. 2016 Jan;52:95-103. Epub 2015 Jul 25

Note: The NASA Task Load Index was used.



Jürgens R, Kliegl K, Kassubek J, Becker W.

Optokinetic circular vection: A test of visual-vestibular conflict models of vection nascensy.

Exp Brain Res. 2015 Sep 10. [Epub ahead of print]



Zhang Y, Li Z, Liu X, Liu F, Jing X, Wu B.

Simulated spaceflight operations under sleep deprivation and confinement.

Aerosp Med Hum Perform. 2015 Sep;86(10):865-74.



Weafer PP, Reynolds NH, Jarvis SP, McGarry JP.

Single cell active force generation under dynamic loading – Part I: AFM experiments.

Acta Biomater. 2015 Sep 7. [Epub ahead of print]



Reynolds NH, McGarry JP.

Single cell active force generation under dynamic loading – Part II: Active modelling insights.

Acta Biomater. 2015 Sep 7. [Epub ahead of print]



Honoré E, Martins JR, Penton D, Patel A, Demolombe S.

The piezo mechanosensitive ion channels: May the force be with you!

Rev Physiol Biochem Pharmacol. 2015 Sep 16:Review.



Wong JY.

On-Site 3D printing of functional custom mallet splints for Mars analogue crewmembers.

Aerosp Med Hum Perform. 2015 Sep;86(10):911-4.



Baykaner KR, Huckvale M, Whiteley I, Andreeva S, Ryumin O.

Predicting fatigue and psychophysiological test performance from speech for safety-critical environments.

Front Bioeng Biotechnol. 2015 Aug 25;3:124.

Note: This article may be obtained online without charge.

SpaceRef staff editor.