NASA Spaceline Current Awareness List #647 – 8 May 2015
Papers deriving from NASA support:
1
Siamwala JH, Lee PC, Macias BR, Hargens AR.
Lower body negative pressure restores leg bone microvascular flow to supine levels during head down tilt.
J Appl Physiol (1985). 2015 Apr 30:jap.00028.2015. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25930022
PI: A.R. Hargens; B.R. Macias, NSBRI Postdoctoral Fellowship Program
Note: A head-down tilt table combined with a lower body negative pressure chamber was used.
Journal Impact Factor: 3.434
Funding: “This work is supported by the Wood Whelan Fellowship (to JHS), National Space Biomedical Research Institute through NCC 9-58 (to BRM). This study was funded by NASA grant NNX13AJ12G (to ARH).”
2
Florian JP, Baisch FJ, Heer M, Pawelczyk JA.
Caloric restriction decreases orthostatic tolerance independently from 6° head-down bedrest.
PLoS One. 2015 Apr 27;10(4):e0118812.
http://www.ncbi.nlm.nih.gov/pubmed/25915488
PI: J.A. Pawelczyk
Note: Bed rest study. This article may be obtained online without charge.
Journal Impact Factor: 3.534
Funding: “This research was supported by National Space Biomedical Research Institute Contract TD00206.”
3
Abdelmoaty H, Hammond TG, Wilson BL, Birdsall HH, Clement JQ.
Identification of putative major space genes using genome-wide literature data.
In: Biotechnology. Rijeka, Croatia: InTech, 2015. p. 93-116.
PI: T.G. Hammond
Note: This article may be obtained online without charge.
Journal Impact Factor: Not applicable to this publication.
Funding: The researcher reports NASA funding under NNX12AM93G.
4
Nusbaum DM, Wu SM, Frankfort BJ.
Elevated intracranial pressure causes optic nerve and retinal ganglion cell degeneration in mice.
Exp Eye Res. 2015 Apr 23. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25912998
PI: D.M. Nussbaum
Note: From the abstract: “The purpose of this study was to develop a novel experimental system for the modulation and measurement of intracranial pressure (ICP), and to use this system to assess the impact of elevated ICP on the optic nerve and retinal ganglion cells (RGCs) in CD1 mice. . .Potentially, this model can also be used to study the relationship between ICP and IOP, as well diseases impacted by ICP variation such as glaucoma, idiopathic intracranial hypertension, and the spaceflight-related visual impairment intracranial pressure syndrome.”
Journal Impact Factor: 3.017
Funding: “This work was supported by NASA Grant NNX 10AK70G (DMN), NIH Grants EY021479 (BJF), EY019908 (SMW), and EY02520 (Ophthalmology Core Grant to Baylor College of Medicine), the Retina Research Foundation (BJF and SMW), Research to Prevent Blindness (BJF and Baylor College of Medicine), and the Oshman Foundation (BJF).”
5
Duda KR, Vasquez RA, Middleton AJ, Hansberry ML, Newman DJ, Jacobs SE, West JJ.
The Variable Vector Countermeasure Suit (V2Suit) for space habitation and exploration.
Front Syst Neurosci. 2015 Apr;9:55.
http://www.ncbi.nlm.nih.gov/pubmed/25914631
PI: K.R. Duda
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this publication
Funding: “This work was supported by Phase I and Phase II grants from NASA’s Innovative Advanced Concepts (NIAC), NNX11AR25G and NNX12AQ58G.”
______________________________________________________
Other papers of interest:
1
Kramer LA, Hasan KM, Sargsyan AE, Wolinsky JS, Hamilton DR, Riascos RF, Carson WK, Heimbigner J, Patel VS, Romo S, Otto C.
MR-derived cerebral spinal fluid hydrodynamics as a marker and a risk factor for intracranial hypertension in astronauts exposed to microgravity.
J Magn Reson Imaging. 2015 Apr 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25920095
2
Morgan M, Grant S, Melmoth D, Solomon JA.
Tilted frames of reference have similar effects on the perception of gravitational vertical and the planning of vertical saccadic eye movements.
Exp Brain Res. 2015 Apr 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25921228
Note: This article may be obtained online without charge.
3
Nicolson T.
Ribbon synapses in zebrafish hair cells.
Hear Res. 2015 Apr 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25916266
4
Alvarado S, Mak T, Liu S, Storey KB, Szyf M.
Dynamic changes in global and gene specific DNA methylation during hibernation in adult thirteen-lined ground squirrels, Ictidomys tridecemlineatus.
J Exp Biol. 2015 Apr 23. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25908059
5
Wang JQ, Qi RR, Zhou W, Tang YF, Pan LL, Cai YL.
Differential gene expression profile in the rat caudal vestibular nucleus is associated with individual differences in motion sickness susceptibility.
PLoS One. 2015 Apr 24;10(4):e0124203.
http://www.ncbi.nlm.nih.gov/pubmed/25910039
Note: Rotation was used to induce motion sickness. This article may be obtained online without charge.
6
Bos JE.
Less sickness with more motion and/or mental distraction.
J Vestib Res. 2015 Jan 1;25(1):23-33.
http://www.ncbi.nlm.nih.gov/pubmed/25882474
Note: Vertical axis rotation was used. This article may be obtained online without charge.
7
Peters RM, Rasman BG, Inglis JT, Blouin JS.
The gain and phase of virtual rotation evoked by electrical vestibular stimuli.
J Neurophysiol. 2015 Apr 29:jn.00114.2015. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25925318
8
O’Shea D, Lackner HK, Rossler A, Green DA, Gauger P, Mulder E, Tamma G, Hinghofer-Szalkay H, Valenti G, Goswami N.
Influence of bedrest on plasma galanin and adrenomedullin at presyncope.
Eur J Clin Invest. 2015 Apr 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25912957
Note: Bed rest study.
9
Meakin LB, Delisser PJ, Galea GL, Lanyon LE, Price JS.
Disuse rescues the age-impaired adaptive response to external loading in mice.
Osteoporos Int. 2015 Apr 29. Epub 2015 Apr 6.
http://www.ncbi.nlm.nih.gov/pubmed/25920749
Note: Neurectomy was used to induce tibial disuse. This article may be obtained online without charge.
10
Eom HS, Park HR, Jo SK, Kim YS, Moon C, Jung U.
Ionizing radiation induces neuronal differentiation of Neuro-2a cells via PI3-kinase and p53-dependent pathways.
Int J Radiat Biol. 2015 Apr 27:1-41. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25912236
11
Yokota Y, Funayama T, Mutou-Yoshihara Y, Ikeda H, Kobayashi Y.
The bystander cell-killing effect mediated by nitric oxide in normal human fibroblasts varies with irradiation dose but not with radiation quality.
Int J Radiat Biol. 2015 May;91(5):383-8.
http://www.ncbi.nlm.nih.gov/pubmed/25908166
12
Hill MA.
FISHing for radiation quality: Chromosome aberrations and the role of radiation track structure.
Radiat Prot Dosimetry. 2015 Apr 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25883310
13
Berardinelli F, Nieri D, Tanzarella C, Cherubini R, De Nadal V, Gerardi S, Sgura A, Antoccia A.
mFISH analysis of irradiated human fibroblasts: A comparison among radiations with different quality in the low-dose range.
Radiat Prot Dosimetry. 2015 Apr 20. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25897136
14
Solov’yov AV, Surdutovich E.
Thermomechanical effects caused by heavy ions propagating in tissue.
Radiat Prot Dosimetry. 2015 Apr 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25911404
15
Maguire A, Vegacarrascal I, White L, McClean B, Howe O, Lyng FM, Meade AD.
Analyses of ionizing radiation effects in vitro in peripheral blood lymphocytes with Raman spectroscopy.
Radiat Res. 2015 Apr;183(4):407-16. Epub 2015 Apr 6.
http://www.ncbi.nlm.nih.gov/pubmed/25844945
16
Shrestha P, Mandal S, Mao H.
Mechanochemical sensing: A biomimetic sensing strategy.
http://www.ncbi.nlm.nih.gov/pubmed/25916512
17
Meng Q, Fang P, Hu Z, Ling Y, Liu H.
Mechanotransduction of trigeminal ganglion neurons innervating inner walls of rat anterior eye chambers.
Am J Physiol Cell Physiol. 2015 Apr 22:ajpcell.00028.2015. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25904679
18
Entradas M.
What is the public’s role in ‘space’ policymaking? Images of the public by practitioners of ‘space’ communication in the United Kingdom.
Public Underst Sci. 2015 Apr 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/25926503
Note: This article may be obtained online without charge.
19
Winter G.
Surgery in space.
Bull R Coll Surg Engl. 2015 May;97(5):208-11.
http://www.ingentaconnect.com/content/rcse/brcs/2015/00000097/00000005/art00011
Note: A science writer interviews NASA PI Scott Dulchavsky and others about the prospects for performing surgery aboard the International Space Station or on other long-duration missions. This article may be obtained online without charge.
