Status Report

NASA Spaceline Current Awareness List #637 – 27 February 2015

By SpaceRef Editor
February 27, 2015
Filed under , , ,

Papers deriving from NASA support:



Zhang L, Kim SB, Jia G, Buhemeida A, Dallol A, Wright WE, Fornace AJ, Al-Qahtani M, Shay JW.

Exome sequencing of normal and isogenic transformed human colonic epithelial cells (HCECs) reveals novel genes potentially involved in the early stages of colorectal tumorigenesis.

BMC Genomics. 2015;16(Suppl 1):S8.

PIs: J.W. Shay; A.J. Fornace/W.E. Wright/NSCOR; J.D. Minna/J.W. Shay/NSCOR

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.041

Funding: “This work was supported by CPRIT Training Grant #RP130189 to LZ, NASA grants NNX09AU95G, NNX11AC15G, and NNX11AC54G to JWS and support from Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah, Saudi Arabia, project no (HiCi-143216-4). This work was performed in laboratories constructed with support from NIH grant C06 RR30414.”



Deng C, Wang P, Zhang X, Wang Y.

Short-term, daily exposure to cold temperature may be an efficient way to prevent muscle atrophy and bone loss in a microgravity environment.

Life Sci Space Res. 2015 Feb 20. [Article in Press]

Journal Impact Factor: 1.183

Funding: “This work was supported by grants from the National Aeronautics and Space Administration (NNX11AC39G) and the National Institutes of Health (P30CA138292).”



Geissler JR, Bajaj D, Fritton JC.

American Society of Biomechanics Journal of Biomechanics Award 2013: Cortical bone tissue mechanical quality and biological mechanisms possibly underlying atypical fractures.

J Biomech. 2015 Feb 2. [Epub ahead of print] Review.

PI: D. Bajaj, NSBRI Postdoctoral Fellowship Program

Note: The Journal of Biomechanics Award is judged based on abstract submissions for the annual American Society of Biomechanics meeting.

Journal Impact Factor: 2.496

Funding: “Publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the NIH (award number AR063351, JCF), the National Space Biomedical Research Institute through NASA contract NCC 9-58 (Fellowship DB) and the NSF GK-12 Graduate Teaching Fellowship Program, New Jersey Space Grant Consortium and Sigma Xi (Fellowships, JRG).”



Suman S, Kallakury BV, Fornace AJ, Jr., Datta K.

Protracted upregulation of leptin and IGF1 is associated with activation of PI3K/Akt and JAK2 pathway in mouse intestine after ionizing radiation exposure.

Int J Biol Sci. 2015 11(3):274-83.

PIs: K. Datta; A.J. Fornace, Jr./K. Datta/NSCOR

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.372

Funding: “This study is supported in part by NASA Grant # NNX13AD58G and NNX09AU95G. We acknowledge the Histopathology and Tissue Shared Resources at Georgetown University supported by Award Number P30CA051008 from the National Cancer Institute.”



Other papers of interest:



Zaripova RI, Andrianov VV, Iafarova GG, Gainutdinov KL, Khabibrakhmanov II, Zefirov TL.

[Influence of hypokinezia of varying duration on the nitric oxide productions dynamics in rat’s heart, spinal cord and liver].

Ross Fiziol Zh Im I M Sechenova. 2014 Aug;100(8):926-35. Russian.

Note: Method used for hypokinesia is not identified.



Balcioglu HE, van Hoorn H, Donato DM, Schmidt T, Danen EH.

Integrin expression profile modulates orientation and dynamics of force transmission at cell matrix adhesions.

J Cell Sci. 2015 Feb 6. [Epub ahead of print]



Bryndina IG, Shalagina MN, Ovechkin SV, Ovchinina NG.

[Sphingolipids in skeletal muscles of C57B1/6 mice after short-term simulated microgravity].

Ross Fiziol Zh Im I M Sechenova. 2014 Nov;100(11):1280-6. Russian.

Note: The method of microgravity simulation is not identified.



Lerebours C, Thomas CD, Clement JG, Buenzli PR, Pivonka P.

The relationship between porosity and specific surface in human cortical bone is subject specific.



McKenna-Lawlor S, Bhardwaj A, Ferrari F, Kuznetsov N, Lal AK, Li Y, Nagamatsu A, Nymmik R, Panasyuk M, Petrov V, Reitz G, Pinsky L, Shukor M, Singhvi AK, Straube U, Tomi L, Lawrence T.

Recommendations to mitigate against human health risks incurred due to energetic particle irradiation beyond low earth orbit/BLEO.

Acta Astronaut. 2015 Apr;109:182-93.



Weyemi U, Redon CE, Aziz T, Choudhuri R, Maeda D, Parekh PR, Bonner MY, Arbiser JL, Bonner WM.

Inactivation of NADPH oxidases NOX4 and NOX5 protects human primary fibroblasts from ionizing radiation-induced DNA damage.

Radiat Res. 2015 Feb 23. [Epub ahead of print]



Hellweg CE.

The nuclear factor kappaB pathway: A link to the immune system in the radiation response.

Cancer Lett. 2015 Feb 14. [Epub ahead of print]



Luu BE, Tessier SN, Duford DL, Storey KB.

The regulation of troponins I, C and ANP by GATA4 and Nkx2-5 in heart of hibernating thirteen-lined ground squirrels, Ictidomys tridecemlineatus.

PLoS One. 2015 Feb 13;10(2):e0117747.

Note: This article may be obtained online without charge.



Barth S, Schraagen JM, Schmettow M.

Network measures for characterising team adaptation processes.



Bastien R, Douady S, Moulia B.

A unified model of shoot tropism in plants: Photo-, gravi- and propio-ception.

PLoS Comput Biol. 2015 Feb;11(2):e1004037.

Note: This article may be obtained online without charge.



Enders TA, Strader LC.

Auxin activity: Past, present, and future.

Am J Bot. 2015 Feb;102(2):180-96. Epub 2015 Jan 29. Review.



Hirano T, Kazama Y, Ishii K, Ohbu S, Shirakawa Y, Abe T.

Comprehensive identification of mutations induced by heavy-ion beam irradiation in Arabidopsis thaliana.

Plant J. 2015 Feb 17. [Epub ahead of print]



Salvi JD, Ó Maoiléidigh D, Fabella BA, Tobin M, Hudspeth AJ.

Control of a hair bundle’s mechanosensory function by its mechanical load.

Proc Natl Acad Sci U S A. 2015 Feb 17. [Epub ahead of print]

Note: This article may be obtained online without charge.



Kim TJ, Joo C, Seong J, Vafabakhsh R, Botvinick EL, Berns MW, Palmer AE, Wang N, Ha T, Jakobsson E, Sun J, Wang Y.

Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs.

Note: This article may be obtained online without charge.



Battista E, Causa F, Lettera V, Panzetta V, Guarnieri D, Fusco S, Gentile F, Netti PA.

Ligand engagement on material surfaces is discriminated by cell mechanosensoring.


SpaceRef staff editor.