Status Report

NASA Spaceline Current Awareness List #624 14 November 2014

By SpaceRef Editor
November 14, 2014
Filed under , , ,

Papers deriving from NASA support:



Reyes DP, McClure SS, Chancellor JC, Blue RS, Castleberry TL, Vanderploeg JM.

Implanted medical devices in the radiation environment of commercial spaceflight.

Aviat Space Environ Med. 2014 Nov;85(11):1106-13. Review.

(PI: J.M. Vanderploeg)

Journal Impact Factor: 0.782

Funding: “The authors further acknowledge the contributions of the FAA Center of Excellence grant for Commercial Space Transportation as well as additional support from the National Space Biomedical Research Institute (NSBRI) through NASA NCC 9-58.”



Goel N, Abe T, Braun ME, Dinges DF.

Cognitive workload and sleep restriction interact to influence sleep homeostatic responses.

(PI: D.F. Dinges)

Journal Impact Factor: 5.062

Funding: “This work was supported by the National Space Biomedical Research Institute through NASA NCC 9-58; by the CTRC UL1 TR000003; by the Japan Society for the Promotion of Science Postdoctoral Fellowships for Research Abroad and by NIH T32 HL07713.



Shao C, Sullivan JP, Girard L, Augustyn A, Yenerall P, Rodriguez-Canales J, Liu H, Behrens C, Shay JW, Wistuba II, Minna JD.

Essential role of aldehyde dehydrogenase 1A3 for the maintenance of non-small cell lung cancer stem cells is associated with the STAT3 pathway.

Clin Cancer Res. 2014 Aug 1;20(15):4154-66. Epub 2014 Jun 6.

(PI: J.D. Minna/W.J. Shay/L. Girard/NSCOR)

Journal Impact Factor: 8.193

Funding: “This project was supported by CPRIT to J.D. Minna, C. Shao, L.Girard, CB, IIW, NCI SPORE P50CA70907 to JDM, CS, LG, CB, JWS, IIW, UTSW Cancer Center Support Grant 5P30-CA142543, the Gillson-Longenbaugh Foundation, to JDM and NSCOR NNX11AC54G to JDM and JWS.”



Zheng X, Zhang X, Ding L, Lee JR, Weinberger PM, Dynan WS.

Synergistic effect of high charge and energy particle radiation and chronological age on biomarkers of oxidative stress and tissue degeneration: A ground-based study using the vertebrate laboratory model organismOryzias latipes.

PLoS One. 2014 Nov 6;9(11):e111362.

(PIs: Y. Wang/W.D. Dynan/NSCOR)

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.534

Funding: “This work was supported by the US Department of Energy Low Dose Radiation Research Program, award number DE-SC0002343 to WSD and the National Aeronautics and Space Administration, award number NNX11AC30G to WSD.”



Badavi FF, Nealy JE.

A deterministic computational model for the two dimensional electron and photon transport.

Acta Astronaut. 2014 Nov 4. [Article in Press]

(PI: J. Norbury)

Journal Impact Factor: 0.816

Funding: “This work was sponsored by the Human Research Program (HRP), under the Human Exploration and Operations Mission Directorate of NASA and partially funded by the NASA Grants NNX12AN58A and NNX09AR20A.”


The Health Risks of Extraterrestrial Environments (THREE) website is “an encyclopedic site whose goal is to present a discussion of the space radiation environment and its health risks to humans…The web site is produced and managed by the Universities Space Research Association Division of Space Life Sciences. Articles posted to this site have been written by investigators and colleagues of the NASA Space Radiation Program and have been reviewed by an Editorial Board.” The website can be found at:


Recent articles posted to the THREE website include:



Datta K, Suman S, Hyduke D, Shaw JW, Fornace AJ Jr.

Developing omic-based approaches for short- and long-term space radiation risk assessment.

(PIs: A.J. Fornace, Jr./K. Datta/J.W. Shay/NSCOR)

Journal Impact Factor: Not applicable.

Funding: “This study is supported by National Aeronautics and Space Administration (NASA) Grant# NNX13AD58G, NNX13AD54G and NNX09AU95G.”



Kennedy EM, Conneely KN, Vertino PM.

Epigenetic memory of space radiation exposure.

(PIs: Y. Wang/P.M. Vertino/NSCOR)

Journal Impact Factor: Not applicable.

Funding: “Supported in part by funds from a US National Aeronautics and Space Administration NSCOR Program grant (NNX11AC30G) to PMV.”



Pirkkanen J, von Neubeck D, Sowa MB.

Summary of an integrated experimental and computational approach to study the effects of heavy ion exposures on skin.

(PI: M.B. Sowa)

Journal Impact Factor: Not applicable.

Funding: “This work was supported by the National Aeronautics and Space Administration [NNX10AB06G] and the Biological and Environmental Research Program, U.S. Department of Energy [DE AC06- 76RLO].”



Other papers of interest:



Truszczynski O, Lewkowicz R, Wojtkowiak M, Biernacki MP.

Reaction time in pilots during intervals of high sustained g.

Aviat Space Environ Med. 2014 Nov;85(11):1114-20.



Hovis JK, Milburn NJ, Nesthus TE.

Protan response times to red lights in a mildly hypoxic environment.

Aviat Space Environ Med. 2014 Nov;85(11):1078-85.



Willems J, Deroanne C, Colige A, Garbacki N.

Cell models adapted to real-time imaging of the cytoskeleton dynamics in altered gravity.

Microgravity Sci Technol. 2014 Nov;26(4):257-70.



Huangfu J, Qi F, Liu H, Zou H, Ahmed MS, Li C.

Novel helper factors influencing recombinant protein production in Pichia pastoris based on proteomic analysis under simulated microgravity.

Appl Microbiol Biotechnol. 2014 Oct 31. [Epub ahead of print]

Note: A Rotary Cell Culture System was used.



Itoh Y, Hayakawa K, Mori T, Agata N, Inoue-Miyazu M, Murakami T, Sokabe M, Kawakami K.

Stand-up exercise training facilitates muscle recovery from disuse atrophy by stimulating myogenic satellite cell proliferation in mice.

Physiol Rep. 2014 Nov 3;2(11). pii: e12185. Print 2014 Nov 1.

Note: Hindlimb suspension study. This article may be obtained online without charge.



Mezil YA, Allison D, Kish K, Ditor D, Ward WE, Tsiani E, Klentrou P.

Response of bone turnover markers and cytokines to high-intensity low-impact exercise.

Med Sci Sports Exerc. 2014 Nov 4. [Epub ahead of print]



Vaughan TJ, Voisin M, Niebur GL, McNamara L.

Multiscale modelling of trabecular bone marrow: Understanding the micromechanical environment of mesenchymal stem cells during osteoporosis.

J Biomech Eng. 2014 Nov 1. [Epub ahead of print]



Metzger TA, Kreipke TC, Vaughan TJ, McNamara L, Niebur GL.

The in situ mechanics of trabecular bone marrow: The potential for mechanobiological response.

J Biomech Eng. 2014 Nov 1. [Epub ahead of print]



Maier J, Cialdai F, Monici M, Morbidelli L.

The impact of microgravity and hypergravity on endothelial cells.

Biomed Res Int. 2014 Nov 10. Review.

Note: Microgravity simulation methods included clinostat, rotating wall vessel bioreactor, and magnetic levitation. Centrifugation was used for hypergravity. Spaceflight and parabolic flight results are included.



Avakyan SV, Kovalenok VV, Savinykh VP, Ivanchenkov AS, Voronin NA, Trchounian A, Baranova LA.

The role of a space patrol of solar X-ray radiation in the provisioning of the safety of orbital and interplanetary manned space flights.

Acta Astronaut.  2014 Nov 4. [Article in Press]



Butler JS, Campos JL, Bülthoff HH.

Optimal visual-vestibular integration under conditions of conflicting intersensory motion profiles.

Exp Brain Res. 2014 Nov 2. [Epub ahead of print]



An Y, Wang S, Hao Z, Zhou Y, Liu Y.

O2 evolution and cyclic electron flow around photosystem I in long-term ground batch culture of Euglena gracilis.

Adv Space Res. 2014 Dec;54(11):2456-65.



Islamov RR, Gusev OA, Tanabe A, Terada M, Tyapkina OV, Petrov KA, Rizvanov AA, Kozlovskaya IB, Nikolskiy EE, Grigorjev AI.

Genomic analysis of mouse lumbar spinal cord after 30-day space flight on biosatellite Bion-M1.

Dokl Biochem Biophys. 2014 Sep;458(1):177-8. Epub 2014 Nov 4.

Note: Bion-M1 results.



Zhang Y, Wang L, Xie J, Zheng H.

Differential protein expression profiling of Arabidopsis thaliana callus under microgravity on board the Chinese SZ-8 spacecraft.

Note: Shenzhou 8 results.



Peyronnet R, Tran D, Girault T, Frachisse JM.

Mechanosensitive channels: Feeling tension in a world under pressure.

Front Plant Sci. 2014 Oct 21;5:558. Review.

Note: This article may be obtained online without charge.



McMurray RJ, Dalby MJ, Tsimbouri PM.

Using biomaterials to study stem cell mechanotransduction, growth and differentiation.

J Tissue Eng Regen Med. 2014 Nov 5. [Epub ahead of print] Review.

Note: This article may be obtained online without charge.



De Vos WH, Beghuin D, Schwarz CJ, Jones DB, van Loon JJ, Bereiter-Hahn J, Stelzer EH.

Invited review article: Advanced light microscopy for biological space research.

Rev Sci Instrum. 2014 Oct;85(10):101101. Review.

Note: This article may be obtained online without charge.


SpaceRef staff editor.