Status Report

NASA Spaceline Current Awareness List #622 31 October 2014

By SpaceRef Editor
October 31, 2014
Filed under , ,

Papers deriving from NASA support:


Ploutz-Snyder LL, Downs M, Ryder J, Hackney K, Scott J, Buxton R, Goetchius E, Crowell B.

Integrated resistance and aerobic exercise protects fitness during bed rest.

Med Sci Sports Exerc. 2014 Feb;46(2):358-68.

(PI: L.L. Ploutz-Snyder)

Note:Bed rest study.

Journal Impact Factor:4.459

Funding:“This work was funded by NASA’s Human Research Program.”


Blue RS, Pattarini JM, Reyes DP, Mulcahy RA, Garbino A, Mathers CH, Vardiman JL, Castleberry TL, Vanderploeg JM.

Tolerance of centrifuge-simulated suborbital spaceflight by medical condition.

Aviat Space Environ Med. 2014 Jul;85(7):721-9.

(PI: J.M. Vanderploeg)

Note:Centrifugation was used.

Journal Impact Factor:0.782

Funding:“The authors acknowledge additional support from the National Space Biomedical Research Institute (NSBRI) through NASA NCC 9-58.”


Stabley JN, Moningka NC, Behnke BJ, Delp MD.

Exercise training augments regional bone and marrow blood flow during exercise.

Med Sci Sports Exerc. 2014 Nov;46(11):2107-12.

(PI: M.D. Delp)

Journal Impact Factor:4.459

Funding:“This study was supported by grants from the National Aeronautics and Space Administration (NNX12AL41G) and the National Institutes of Health (AG-31317).”


Ni J, Romero-Weaver AL, Kennedy AR.

Potential beneficial effects of Si-Wu-Tang on white blood cell numbers and the gastrointestinal tract of -ray irradiated mice.

Int J Biomed Sci. 2014 Sep;10(3):182-90.

(PI: A.R. Kennedy)

Note:This article may be obtained online without charge.

Journal Impact Factor:Not available for this journal.

Funding:“This study was supported by a grant from the National Space Biomedical Research Institute (NSBRI). The NSBRI is funded through the National Aeronautics and Space Administration (NASA) Class Code (NCC) 9-58. Dr. Jin Ni was supported by the State Scholarship Fund of China Scholarship Council (No.2011317036). Dr. Ana Romero-Weaver was supported by NIH Training Grant 2T32CA009677.”


Parihar VK, Pasha J, Tran KK, Craver BM, Acharya MM, Limoli CL.

Persistent changes in neuronal structure and synaptic plasticity caused by proton irradiation. Brain Struct Funct. 2014 Jan 21. [Epub ahead of print]

(PI: C.L. Limoli)

Journal Impact Factor:4.567

Funding:“This work was supported by the National Institutes of Health NINDS Grant R01 NS074388 (CLL) and by NASA Grants NNX13AD59G and NNX10AD59G (CLL).”


White RC, Yu T, Gupta K, Babitz SK, Black LL, Kabarowski JH, Kucik DF.

Early changes in vascular reactivity in response to 56Fe irradiation in ApoE -/- mice.

Acta Astronat. 2014 Oct 16. [Article in Press]

(PI: D.F. Kucik)

Journal Impact Factor:0.816

Funding:“This work was supported by NASA grant NNX11AC61G.”


Yan X, Sasi SP, Gee H, Lee J, Yang Y, Mehrzad R, Onufrak J, Song J, Enderling H, Agarwal A, Rahimi L, Morgan J, Wilson PF, Carrozza J, Walsh K, Kishore R, Goukassian DA.

Cardiovascular risks associated with low dose ionizing particle radiation.

PLoS One. 2014 Oct 22;9(10):e110269.

(PI: D.A. Goukassian)

Note:This article may be obtained online without charge.

Journal Impact Factor:3.534

Funding:“This material is based upon work supported by the National Aeronautic and Space Administration under Grant No. NNJ10ZSA001N to DAG and in part by grants from AHA 14GRNT18860032 to DAG, AHA grant 10GRNT4710003 and NHLBI HL106098 to XY, and NIH HL091983 to RK.”


Li Z, Wang H, Wang Y, Murnane JP, Dynan WS.

Effect of radiation quality on mutagenic joining of enzymatically-induced DNA double-strand breaks in previously irradiated human cells.

Radiat Res. 2014 Oct 20. [Epub ahead of print]

(PIs: Y. Wang/H. Wang/W.S. Dynan/NSCOR)

Journal Impact Factor:3.534

Funding:“An NSCOR award from the U.S. National Aeronautic and Space Administration (no. NNX11AC30G) supported this work.”


Wheeler KT, Payne V, D’Agostino RB Jr, Walb MC, Munley MT, Metheny-Barlow LJ, Robbins ME.

Impact of breathing 100% oxygen on radiation-induced cognitive impairment.

Radiat Res. 2014 Oct 22. [Epub ahead of print]

Journal Impact Factor:2.445

Funding:“This work was supported by NIH grant, CA112593 (MER, LJM) from NCI and two NASA sponsored supplements, CA112593-S1 (MER) and CA136910-S1 (MTM).”


Assad A, de Weck OL.

Model of medical supply and astronaut health for long-duration human space flight.

Acta Astronaut. 2014 Oct 12. [Article in Press]

Journal Impact Factor:0.816

Funding:“The authors would gratefully like to acknowledge NASA and the Exploration Systems Mission Directorate for funding this research, (Grant number NNX06AH24H).”


Other papers of interest:


Li X, Wang X, Li Y, Zhu J, Su X, Yao X, Fan X, Duan Y.

The activity, protein, and mRNA expression of CYP2E1 and CYP3A1 in rats after exposure to acute and chronic high altitude hypoxia.

High Alt Med Biol. 2014 Oct 20. [Epub ahead of print]


Borges JB, Hedenstierna G, Bergman JS, Amato MB, Avenel J, Montmerle-Borgdorff S.

First-time imaging of effects of inspired oxygen concentration on regional lung volumes and breathing pattern during hypergravity.

Eur J Appl Physiol. 2014 Oct 17. [Epub ahead of print]

Note:Centrifugation was used.


White JP, Wrann CD, Rao RR, Nair SK, Jedrychowski MP, You JS, Martnez-Redondo V, Gygi SP, Ruas JL, Hornberger TA, Wu Z, Glass DJ, Piao X, Spiegelman BM.

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy.

Proc Natl Acad Sci U S A. 2014 Oct 21. pii: 201417898. [Epub ahead of print]


Schneider S, Peipsi A, Stokes M, Knicker A, Abeln V.

Feasibility of monitoring muscle health in microgravity environments using Myoton technology.

Med Biol Eng Comput. 2014 Oct 21. [Epub ahead of print]

Note:Parabolic flight results.


Meakin LB, Price JS, Lanyon LE.

The contribution of experimental in vivo models to understanding the mechanisms of adaptation to mechanical loading in bone.

Front Endocrinol (Lausanne). 2014 Oct 1;5:154. Review.

Note:Models of mechanical loading discussed include artificial loading of bones in vivo with external devices, attaching electrical resistance strain gages to bone surfaces, and non-invasive transcutaneous loading in rats and mice such as the four-point and cantilever bending models. Models of mechanical unloading include hindlimb suspension, sciatic or tibial denervation, and injection of botulinum toxin. This article may be obtained online without charge.


Yatagai F, Ishioka N.

Are biological effects of space radiation really altered under the microgravity environment?

Life Sci. Space Res.2014 Oct 23. [Article in Press] Review.

Note:Reviews both space- and ground-based studies.


Calabrese EJ, O’Connor MK.

Estimating risk of low radiation doses – A critical review of the BEIR VII Report and its use of the linear no-threshold (LNT) hypothesis.

Radiat Res. 2014 Oct 20. [Epub ahead of print]

Note:The National Research Council’s report onBiological Effects of Ionizing Radiation VII Phase 2(BEIR VII) develops risk estimates for exposure to low-dose, low linear energy transfer (LET) radiation in humans.


Rosenberg A, Angelaki DE.

Gravity influences the visual representation of object tilt in parietal cortex.

J Neurosci. 2014 Oct 22;34(43):14170-80.


Ramaioli C, Colagiorgio P, Salam M, Heuser F, Schneider E, Ramat S, Lehnen N.

The effect of vestibulo-ocular reflex deficits and covert saccades on dynamic vision in opioid-induced vestibular dysfunction.

PLoS One. 2014 Oct 20;9(10):e110322.

Note:This article may be obtained online without charge.


Wong AM.

New understanding on the contribution of the central otolithic system to eye movement and skew deviation.

Eye (Lond). 2014 Oct 17. [Epub ahead of print]


Modarres HP, Mofradt MR.

Filamin: A structural and functional biomolecule with important roles in cell biology, signaling and mechanics.

Mol Cell Biomech. 2014 Mar;11(1):39-65. Review.


Sun J, Xiao Y, Wang S, Slepian MJ, Wong PK.

Advances in techniques for probing mechanoregulation of tissue morphogenesis.

J Lab Autom. 2014 Oct 20. pii: 2211068214554802. [Epub ahead of print] Review.


Cai T, Groves AK.

The role of atonal factors in mechanosensory cell specification and function.

Mol Neurobiol. 2014 Oct 23. [Epub ahead of print]


Hu WR, Zhao JF, Long M, Zhang XW, Liu QS, Hou MY, Kang Q, Wang YR, Xu SH, Kong WJ, Zhang H, Wang SF, Sun YQ, Hang HY, Huang YP, Cai WM, Zhao Y, Dai JW, Zheng HQ, Duan EK, Wang JF.

Space program SJ-10 of microgravity research.

Microgravity Sci Technol. 2014 Oct;26(3):159-69.

Note:From the abstract: “SJ-10 program provides a mission of space microgravity experiments including both fields of microgravity science and space life science aboard the 24threcoverable satellite of China.”


Frett T, Mayrhofer M, Schwandtner J, Anken R, Petrat G.

An innovative short arm centrifuge for future studies on the effects of artificial gravity on the human body.

Microgravity Sci Technol. 2014 Sep 19. [Article in Press].


Howell E.

NASA spots creepy face on the sun (Photos).

  1. . 2014 Oct 14.

Note:A timely photograph from NASA’s Solar Dynamics Observatory.

SpaceRef staff editor.