Status Report

NASA Spaceline Current Awareness List #617 26 September 2014

By SpaceRef Editor

September 26, 2014

Filed under ISS, Spaceline, Spaceline Current Awareness, US

Papers deriving from NASA support:

De Witt JK, Edwards WB, Scott-Pandorf MM, Norcross JR, Gernhardt ML.

The preferred walk to run transition speed in actual lunar gravity.

J Exp Biol. 2014 Sep 15;217(Pt 18):3200-3.

http://www.ncbi.nlm.nih.gov/pubmed/25232195

(PI: J.K. De Witt)

Note:Parabolic flight results. Over-head suspension was used to simulate lunar gravity.

Journal Impact Factor:3.002

Funding:“This work was a directed study funded by the Human Health and Countermeasures Element of the National Aeronautics and Space Administration’s Human Research Program.”

Johnston SL, Blue RS, Jennings RT, Tarver WJ, Gray GW.

Astronaut medical selection during the Shuttle era: 1981-2011.

Aviat Space Environ Med. 2014 Aug;98(8):823-7.

http://www.ingentaconnect.com/content/asma/asem/2014/00000085/00000008/art00007

Journal Impact Factor:0.782

Funding:No funding cited. S.L. Johnston and W.J. Tarver are at NASA Johnson Space Center.

Respress JL, Gershovich PM, Wang T, Reynolds JO, Skapura DG, Sutton JP, Miyake CY, Wehrens XH.

Long-term simulated microgravity causes cardiac RyR2 phosphorylation and arrhythmias in mice.

Int J Cardiol. 2014 Sep 6. pii: S0167-5273(14)01685-4. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25227892

(PI: P.M. Gershovich, NSBRI Postdoctoral Fellowship Program)

Note:Hindlimb unloading study.

Journal Impact Factor:6.175

Funding:“X.H.T.W. is an American Heart Association Established Investigator (grant 13EIA14560061), and is supported by NIH grants HL089598, HL091947, and HL117641, a Muscular Dystrophy Association grant (186530), and the Juanita P. Quigley Endowed Chair in Cardiology (at Baylor College of Medicine). J.L.R. is a recipient of the NIH Training Grant Science Award T32-HL07676. P.M.G. is a recipient of the National Space Biomedical Research Institute (NSBRI) Postdoctoral Fellowship Award (NCC 9-58). J.P.S. acknowledges the support of the Friedkin Chair for Research in Sensory System Integration and Space Medicine (at Baylor College of Medicine).”

Swift SN, Swift JM, Bloomfield SA.

Mechanical loading increases detection of estrogen receptor-alpha in osteocytes and osteoblasts despite chronic energy restriction.

J Appl Physiol (1985). 2014 Sep 11. pii: jap.00588.2013. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25213639

(PI: S.A. Bloomfield)

Journal Impact Factor:3.434

Funding:“SNS and JMS were supported by Dept. of Defense project #WSIXWH-06-1-0479 and National Space Biomedical Research Institute Project #MA01602 via NASA Cooperative Agreement NCC9-58, respectively.”

Wang H, Wang Y.

Heavier ions with a different linear energy transfer spectrum kill more cells due to similar interference with the Ku-dependent DNA repair pathway.

Radiat Res. 2014 Sep 17. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25229976

(PI: Y. Wang/NSCOR)

Journal Impact Factor:2.445

Funding:“This work is supported by the National Aeronautics and Space Administration (grant no. NNX11AC30G, YW).”

Brandizzi F, Frigerio L, Howell SH, Schfer P.

Endoplasmic reticulum-shape and function in stress translation.

Front Plant Sci. 2014 Sep 1;5:425. Editorial.

http://www.ncbi.nlm.nih.gov/pubmed/25225498

(PI: F. Brandizzi)

Note:This article may be obtained online without charge.

Journal Impact Factor:3.637

Funding:“Research in the lab of Federica Brandizzi is supported by the NIH, NASA, NSF, and DOE. Research in the lab of Lorenzo Frigerio is supported by the BBSRC and the Leverhulme Trust. Research in the lab of Patrick Schfer is supported by the Deutsche Forschungsgemeinschaft (DFG), BASF and the University of Warwick.”

The journalLife, a publication of the Multidisciplinary Digital Publishing Institute (MDPI), has produced a special issue “Response of Terrestrial Life to Space Conditions,” edited by David M. Klaus.Lifeis an open access journal and the articles are available free of charge at the publisher’s website:http://www.mdpi.com/journal/life/special_issues/space-conditions.

The articles include recent research and reviews of prior studies; those written with NASA support are included in this section of Current Awareness. The remaining articles are listed at the end of the ‘Other papers of interest’ section.

Clment G, Skinner A. Lathan C.

Distance and size perception in astronauts during long-duration spaceflight.

http://www.mdpi.com/2075-1729/3/4/524

(PI: C. Lathan)

Note:ISS results. This article may be obtained online without charge.

Journal Impact Factor:Not available for this journal.

Funding:“This work was supported by the Centre National d’Etudes Spatiales (CNES), the European Space Agency (ESA), and the National Aeronautics and Space Administration (NASA).”

Foster JS, Wheeler RM, Pamphile R.

Host-microbe interactions in microgravity: Assessment and implications.

http://www.mdpi.com/2075-1729/4/2/250

(PI: J.S. Foster)

Note:This article may be obtained online without charge.

Journal Impact Factor:Not available for this journal.

Funding:“This work was supported by the Florida Space Research Institute and the NASA Space Biology program (NNX13AM44G) awarded to J.S.F.”

Nagaraja MP, Jo H.

The role of mechanical stimulation in recovery of bone loss High versus low magnitude and frequency of force.

http://www.mdpi.com/2075-1729/4/2/117

Note:This article may be obtained online without charge.

Journal Impact Factor:Not available for this journal.

Funding:“Hanjoong Jo’s work was supported by funding from NIH grants HL095070, HL70531 and HHSN268201000043C.” M.P. Nagaraja is at NASA Johnson Space Center.

Chancellor, JC, Scott GBL, Sutton JP.

Space radiation: The number one risk to astronaut health beyond low earth orbit.

http://www.mdpi.com/2075-1729/4/3/491

Note:This article may be obtained online without charge.

Journal Impact Factor:Not available for this journal.

Funding:“The authors (Jeffery C. Chancellor, Graham B. I. Scott and Jeffrey P. Sutton) acknowledge support from the National Space Biomedical Research Institute through NASA cooperative agreement NCC 9-58. Support from the Friedkin Chair for Research in Sensory System Integration and Space Medicine (to Jeffrey P. Sutton) is also acknowledged.”

__________________________________________________________________________

Other papers of interest:

Chelyshev YA, Muhamedshina YO, Povysheva TV, Shaymardanova GF, Rizvanov AA, Nigmetzyanova MV, Tiapkina OV, Bondarenko NI, Nikolskiy EE, Islamov RR.

Characterization of spinal cord glial cells in a model of hindlimb unloading in mice.

http://www.ncbi.nlm.nih.gov/pubmed/25218808

Note:Hindlimb unloading study.

Masiello MG, Cucina A, Proietti S, Palombo A, Coluccia P, D’Anselmi F, Dinicola S, Pasqualato A, Morini V, Bizzarri M.

Phenotypic switch induced by simulated microgravity on MDA-MB-231 breast cancer cells.

Biomed Res Int. 2014;2014:652434. Epub 2014 Aug 18.

http://www.ncbi.nlm.nih.gov/pubmed/25215287

Note:A random positioning machine was used. This article may be obtained online without charge.

Jrgensen PG, Arnemo J, Swenson JE, Jensen JS, Galatius S, Frbert O.

Low cardiac output as physiological phenomenon in hibernating, free-ranging Scandinavian brown bears (Ursus arctos) – An observational study.

Cardiovasc Ultrasound. 2014 Sep 16;12:36.

http://www.ncbi.nlm.nih.gov/pubmed/25224464

Note:This article may be obtained online without charge.

Hockerman GH, Dethrow NM, Hameed S, Doran M, Jaeger C, Wang WH, Pond AL.

The Ubr2 gene is expressed in skeletal muscle atrophying as a result of hind limb suspension, but not Merg1a expression alone.

Eur J Transl Myol. 2014 Mar 31;24(3):173-179.

http://www.ncbi.nlm.nih.gov/pubmed/25232465

Note:Hindlimb unloading study. This article may be obtained online without charge.

Lau YC, Qian X, Po KT, Li LM, Guo X.

Electrical stimulation at the dorsal root ganglion preserves trabecular bone mass and microarchitecture of the tibia in hindlimb-unloaded rats.

Osteoporos Int. 2014 Sep 12. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25212672

Note:Hindlimb unloading study.

Safer U, Tasci I, Cintosun U, Safer VB.

Nutrition interventions in bed rest trials.

J Appl Physiol (1985). 2014 Sep 15;117(6):679. Letter.

http://www.ncbi.nlm.nih.gov/pubmed/25225227

Note:This letter is a comment onPMID 24790012 by Krainski, et al., “The effect of rowing ergometry and resistive exercise on skeletal muscle structure and function during bed rest,” cited in Current Awareness List #601, 6 June 2014. The authors’ reply is PMID 25225228:http://www.ncbi.nlm.nih.gov/pubmed/25225228. These articles may be obtained online without charge.

Asakawa JI, Kamiguchi Y, Kamiya K, Nakamura N.

Mutagenic effects of ionizing radiation on immature rat oocytes.

Radiat Res. 2014 Sep 17. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25229977

Hada M, Chappell LJ, Wang M, George KA, Cucinotta FA.

Induction of chromosomal aberrations at fluences of less than one HZE particle per cell nucleus.

Radiat Res. 2014 Sep 17. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25229974

Wanyan X, Zhuang D, Zhang H.

Improving pilot mental workload evaluation with combined measures.

Biomed Mater Eng. 2014 Jan 1;24(6):2283-90.

http://www.ncbi.nlm.nih.gov/pubmed/25226928

Note:Pilot behavioral performance evaluation was based on the NASA Task Load Index. This article may be obtained online without charge.

Kosmadopoulos A, Sargent C, Darwent D, Zhou X, Dawson D, Roach GD.

The effects of a split sleep-wake schedule on neurobehavioural performance and predictions of performance under conditions of forced desynchrony.

Chronobiol Int. 2014 Sep 15:1-9. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25222348

Note:This article may be obtained online without charge.

Singh NK, Pandey P, Mahesh S.

Assessment of otolith function using cervical and ocular vestibular evoked myogenic potentials in individuals with motion sickness.

http://www.ncbi.nlm.nih.gov/pubmed/25220694

Desai M, Rangarajan P, Donahue JL, Williams SP, Land ES, Mandal MK, Phillippy BQ, Perera IY, Raboy V, Gillaspy GE.

Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants.

Plant J. 2014 Sep 17. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25231822

Huang JB, Liu H, Chen M, Li X, Wang M, Yang Y, Wang C, Huang J, Liu G, Liu Y, Xu J, Cheung AY, Tao LZ.

ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth inArabidopsis.

Plant Cell. 2014 Sep 12. pii: tpc.114.127902. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25217509

Starke J, Wehrle-Haller B, Friedl P.

Plasticity of the actin cytoskeleton in response to extracellular matrix nanostructure and dimensionality.

Biochem Soc Trans. 2014 Oct 1;42(5):1356-66.

http://www.ncbi.nlm.nih.gov/pubmed/25233415

Zhong D, Blount P.

Electrostatics at the membrane define MscL channel mechanosensitivity and kinetics.

FASEB J. 2014 Sep 15. pii: fj.14-259309. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/25223610

The remaining citations are from theLifespecial issue “Response of Terrestrial Life to Space Conditions:”

Leuko S, Rettberg P, Pontifex A, Burns B.

On the response of halophilic Archaea to space conditions.

http://www.mdpi.com/2075-1729/4/1/66

Note:Ground-based simulation and space flight results are discussed. This article may be obtained online without charge.

Zeredo Z, Toda K, Kumei Y.

Neuronal activity in the subthalamic cerebrovasodilator area under partial-gravity conditions in rats.

http://www.mdpi.com/2075-1729/4/1/107

Note:Parabolic flight results. This article may be obtained online without charge.

Hasegawa K, de Campos P, Zeredo J, Kumei Y.

Cineradiographic analysis of mouse postural response to alteration of gravity and jerk (gravity deceleration rate).

http://www.mdpi.com/2075-1729/4/2/174

Note:Parabolic flight results. This article may be obtained online without charge.

Bradamante S, Barenghi L, Maier J.

Stem cells toward the future: The space challenge.

http://www.mdpi.com/2075-1729/4/2/267

Note:Results from simulated microgravity and space flight studies are discussed. This article may be obtained online without charge.

De la Torre G.

Cognitive neuroscience in space.

http://www.mdpi.com/2075-1729/4/3/281

Note:This article may be obtained online without charge.

Hackney K, English, K.

Protein and essential amino acids to protect musculoskeletal health during spaceflight: Evidence of a paradox?

http://www.mdpi.com/2075-1729/4/3/295

Note:This article may be obtained online without charge.

The following citations appeared in previous Lists:

Wolff S, Coelho L, Karoliussen I, Jost A.

Effects of the extraterrestrial environment on plants: Recommendations for future space experiments for the MELiSSA higher plant compartment.

http://www.mdpi.com/2075-1729/4/2/189

Note:This article was in CA 610, 8 Aug 2014.

Hoson T.

Plant growth and morphogenesis under different gravity conditions: Relevance to plant life in space.

http://www.mdpi.com/2075-1729/4/2/205

Note:This article was in CA 609, 1 Aug 2014.

SpaceRef Editor

SpaceRef staff editor.

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