Status Report

NASA SPACELINE Current Awareness List #615 12 September 2014

By SpaceRef Editor
September 12, 2014
Filed under , , ,

Papers deriving from NASA support:


Monsieurs P, Mijnendonckx K, Provoost A, Venkateswaran K, Ott CM, Leys N, Van Houdt R.

Draft genome sequences ofRalstonia pickettiistrains SSH4 and CW2, isolated from space equipment.

Genome Announc. 2014 Sep 4;2(5). pii: e00887-14.

Note:ISS results. From the abstract: “Ralstonia pickettiiSSH4 and CW2 are Gram-negative bacteria (Burkholderiaceaefamily) isolated pre-flight from the surface of the Mars Odyssey Orbiter during assembly at the Kennedy Space Center in Florida and from a water sample taken in-flight from the American segment of the International Space Station (ISS) cooling system, respectively.” This article may be obtained online without charge.

Journal Impact Factor:Not available for this journal.

Funding:“This work was supported by the European Space Agency (ESA-PRODEX) and the Belgian Science Policy (Belspo) through the COMICS project (C90356).”


Gale RP, Hlatky L, Sachs RK, Radivoyevitch T.

Why is there so much therapy-related AML and MDS and so little therapy-related CML?

Leuk Res. 2014 Aug 11. pii: S0145-2126(14)00235-5. [Epub ahead of print]

(PI: L. Hlatky, L. Hlatky/NSCOR)

Journal Impact Factor:2.692

Funding:“LH and RKS were supported by Award Number U54CA149233 from the National Cancer Institute (to LH) and by the National Aeronautics and Space Administration under grant nos. NNJ06HA28G/NNX11AK26G and NNX13AJ01G issued through the Human Research Program (to LH). NIH RO1CA138858 (TR). RPG thanks the NIHR Biomedical Research Centre funding scheme.”


Qin Q, Xie H, Wise SS, Browning CL, Thompson KN, Holmes AL, Wise JP Sr.

Homologous recombination repair signaling in chemical carcinogenesis: Prolonged particulate hexavalent chromium exposure suppresses the Rad51 response in human lung cells.

Toxicol Sci. 2014 Aug 30. pii: kfu175. [Epub ahead of print]

(PI: J.P. Wise)

Journal Impact Factor:4.478

Funding:“National Institute of Environmental Health Sciences (ES016893 to J.P.W.); National Aeronautics and Space Administration (NASA) (ACD FSB-2009 to J.P.W.); Maine Center for Toxicology and Environmental Health. Funding for open access charge: National Institutes of Health (ES016893 to J.P.W.); NASA (ACD FSB-2009 to J.P.W.).”


Mellor LF, Baker TL, Brown RJ, Catlin LW, Oxford JT.

Optimal 3D culture of primary articular chondrocytes for use in the rotating wall vessel bioreactor.

Aviat Space Environ Med. 2014 Aug;85(8):798-804.

(PI: L.F. Mellor, NSBRI Postdoctoral Fellowship Program)

Note:A rotating wall vessel bioreactor was used.

Journal Impact Factor:0.782

Funding:“This work was supported in part by the National Space Biomedical Research Institute through NASA NCC9-58, the Idaho Space Grant Consortium, NASA (NNX10AN29A), the Arthritis Foundation, NIH/NIAMS Grants R01AR047985 and K02AR48672, NIH/NCRR Grant P20RR016454, NIH/NIGMS P20GM103408, the National Science Foundation (0619793, 0923535), the M. J. Murdock Charitable Trust, and the Idaho State Board of Education Higher Education Research Council for support of the Musculoskeletal Research Institute.”


Britten RA, Davis LK, Jewell JS, Miller VD, Hadley MM, Sanford LD, Machida M, Lonart G.

Exposure to mission relevant doses of 1 GeV/nucleon (56)Fe particles leads to impairment of attentional set-shifting performance in socially mature rats.

Radiat Res. 2014 Sep;182(3):292-8. Epub 2014 Jul 16.

(PI: R.A. Britten)

Journal Impact Factor:2.445

Funding:“This work was funded by NASA grant support NNJ06HD89D and NNX11AC56G (RB) and by NIH research grant MH64827 (LS).”


Liber HL, Idate R, Warner C, Bailey SM.

Radiation quality and mutagenesis in human lymphoblastoid cells.

Radiat Res. 2014 Sep 3. [Epub ahead of print]

(PI: H.L. Liber)

Journal Impact Factor:2.445

Funding:“This work was funded by NASA grant NNX10AB36G.”


Cohen HS, Mulavara AP, Sangi-Haghpeykar H, Peters BT, Bloomberg JJ, Pavlik VN.

Screening people in the waiting room for vestibular impairments.

South Med J. 2014 Sep;107(9):549-53.

(PIs: J.J. Bloomberg, A.P. Mulavara)

Journal Impact Factor:1.116

Funding:“The study was supported by National Institutes of Health grant R01DC009031 (HSC) and grants from the National Space Biomedical Research Institute through NASA NCC 9-58 (A.P.M. and J.J.B.).V.N.P. has received grants from the Agency for Healthcare Research and Quality.”


Wu L, Boyd JL, Daniels V, Wang Z, Chow DS, Putcha L.

Dose escalation pharmacokinetics of intranasal scopolamine gel formulation.

J Clin Pharmacol. 2014 Sep 4. [Epub ahead of print]

(PI: L. Putcha)

Journal Impact Factor:2.472

Funding:“This work was supported by a grant from the National Space Biomedical Research Institute.”


Dean DA 2nd, Adler GK, Nguyen DP, Klerman EB.

Biological time series analysis using a context free language: Applicability to pulsatile hormone data.

PLoS One. 2014 Sep 3;9(9):e104087.

(PI: E.B. Klerman)

Note:This article may be obtained online without charge.

Journal Impact Factor:3.534

Funding:“This work received funding from the following sources: AFOSR F49620-95-1-0388, FA9550-06-0080; NIH NCRR-GCRC-M01-RR-02635, P01-AG09975, T32 HL07901-10 (DAD), F31-GM095340-01 (DAD), K24-HL105664 (EBK), K02-HD045459 (EBK), RC2-HL101340, R01-AR43130 (GKA), K24-HL103845 (GKA), R01-MH071847, R01 HL098433, and R01 HL098433-02S1(DAD), NSBRI through NASA NCC 9-58 HFP01603 and HPF00405.”


Other papers of interest:


Kim HS, Jung YY, Do SI.

Hepatic inducible nitric oxide synthase expression increases upon exposure to hypergravity.

Braz J Med Biol Res. 2014 Aug 29;0:0. [Epub ahead of print]

Note:Centrifugation was used. This article may be obtained online without charge.


Siques P, Brito J, Naveas N, Pulido R, De la Cruz JJ, Mamani M, Len-Velarde F.

Plasma and liver lipid profiles in rats exposed to chronic hypobaric hypoxia: Changes in metabolic pathways.

High Alt Med Biol. 2014 Sep 3. [Epub ahead of print]


Shi HZ, Li YZ, Tang ZZ, Zhong CF, Fan QC, Gao JY, Liu JL, Mi T, Zhao S, Li YH.

Impact of 60 days of 6 head down bed rest on cardiopulmonary function, and the effects of Taikong Yangxin prescription as a countermeasure.

Chin J Integr Med. 2014 Sep;20(9):654-60. Epub 2014 May 8.

Note:Bed rest study.


Blanque R, Lepescheux L, Auberval M, Minet D, Merciris D, Cottereaux C, Clment-Lacroix P, Delerive P, Namour F.

Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization.

BMC Musculoskelet Disord. 2014 Sep 3;15(1):291. [Epub ahead of print]

Note:Hindlimb unloading study. This article may be obtained online without charge.


Shenton F, Bewick GS, Banks RW.

A study of the expression of small conductance calcium-activated potassium channels (SK1-3) in sensory endings of muscle spindles and lanceolate endings of hair follicles in the rat.

PLoS One. 2014 Sep 5;9(9):e107073.

Note:This article may be obtained online without charge.


Barcellos-Hoff MH, Cucinotta FA.

New tricks for an old fox: Impact of TGF on the DNA damage response and genomic stability.

Sci Signal. 2014 Sep 2;7(341):re5. Review.


Hardee JP, Puppa MJ, Fix DK, Gao S, Hetzler KL, Bateman TA, Carson JA.

The effect of radiation dose on mouse skeletal muscle remodeling.

Radiol Oncol. 2014 Jul 10;48(3):247-56.

Note:This article may be obtained online without charge.


Osborne JR, Lanza MVA, Desclaux DF, Goswami N, Alonso DVG, Moser M, Grote V, Garcia-Cuadrado G, Perez-Poch A.

Effect of mental arithmetic on heart rate responses during parabolic flights: The Barcelona Zero-G Challenge.

Microgravity Sci Technol. 2014 Jul;26(1):11-6.

Note:Parabolic flight results.


Tarnutzer AA, Bockisch CJ, Straumann D, Marti S, Bertolini G.

Static roll-tilt over five minutes locally distorts the internal estimate of direction of gravity.

J Neurophysiol. 2014 Sep 3. pii: jn.00540.2014. [Epub ahead of print]

Note:A three-axis motor-driven turntable was used.


Harris LR, Herpers R, Hofhammer T, Jenkin M.

How much gravity is needed to establish the perceptual upright?

PLoS One. 2014 Sep 3;9(9):e106207.

Note:A short-arm centrifuge was used. This article may be obtained online without charge.


Soga K, Biology Club, Kurita A, Yano S, Ichikawa T, Kamada M, Takaoki M.

Growth and morphogenesis of azuki bean seedlings in space during SSAF2013 program.

Biol Sci Space. 2014 Aug 23;28:6-11.

Note:ISS results. From the article: “The “Space Seeds for Asian Future (SSAF)” program is one of the activities of the “Asian Beneficial Collaboration through Kibo Utilization (Kibo-ABC)” initiative under the “Asia-Pacific Regional Space Agency Forum (APRSAF)”… In the SSAF2013 program, seeds of the azuki bean were germinated and their seedlings were cultivated by astronauts in the Kibo.”


Nakano M, Samejima R, Iida H.

Mechanosensitive channel candidate MCA2 is involved in touch-induced root responses inArabidopsis.

Front Plant Sci. 2014 Aug 21;5:421.

Note:This article may be obtained online without charge.


Leblanc-Fournier N, Martin L, Lenne C, Decourteix M.

To respond or not to respond, the recurring question in plant mechanosensitivity.

Front Plant Sci. 2014 Aug 14;5:401. Review.

Note:This article may be obtained online without charge.


Simon DD, Murtada SI, Humphrey JD.

Computational model of matrix remodeling and entrenchment in the free-floating fibroblast-populated collagen lattice.

Int J Numer Method Biomed Eng. 2014 Sep 1. [Epub ahead of print]


Snedeker JG.

The nuclear envelope as a mechanostat: A central cog in the machinery of cell and tissue regulation?

Bonekey Rep. 2014 Aug 13;3:562.

SpaceRef staff editor.