Status Report

NASA Spaceline Current Awareness List #610 8 August 2014

By SpaceRef Editor
August 8, 2014
Filed under , , ,
Papers deriving from NASA support:
Yi B, Rykova M, Feuerecker M, Jäger B, Ladinig C, Basner M, Hörl M, Matzel S, Kaufmann I, Strewe C, Nichiporuk I, Vassilieva G, Rinas K, Baatout S, Schelling G, Thiel M, Dinges DF, Morukov B, Choukèr A.
520-d Isolation and confinement simulating a flight to Mars reveals heightened immune responses and alterations of leukocyte phenotype.
Brain Behav Immun. 2014 Aug;40:203-10. Epub 2014 Apr 2.
(PIs: M. Basner, D.F. Dinges)
Note: Mars520 isolation study.
Journal Impact Factor: 6.12
Funding: “A. Choukèr has received a financial support (Grant No. 50WB0919, 50WB1317) from the German Ministry of Technology and Economics (BMWi as handled by DLR). The work of M. Basner and D. F. Dinges was funded by the National Space Biomedical Research Institute (NSBRI) through NASA NCC 9-58 and by the Institute for Experimental Psychiatry Research Foundation. S.B. received a financial support from the BELSPO/PRODEX/ESA contract (42-000-90-380).”
Wang JH, Singh R, Benoit M, Keyhan M, Sylvester M, Hsieh M, Thathireddy A, Hsieh YJ, Matin AC.
Sigma S-dependent antioxidant defense protects stationary phase Escherichia coliagainst the bactericidal antibiotic gentamicin.
Antimicrob Agents Chemother. 2014 Jul 28. pii: AAC.03683-14. [Epub ahead of print]
(PI: A.C. Matin)
Journal Impact Factor: 4.565
Funding: “This research was supported by NASA grants NNX09AH41G and NNX10AM90A to AM; and NIH DK087895 to MH.”
Bajaj D, Geissler JR, Allen MR, Burr DB, Fritton JC.
The resistance of cortical bone tissue to failure under cyclic loading is reduced with alendronate.
(PI: D. Bajaj, NSBRI Postdoctoral Fellowship Program)
Journal Impact Factor: 3.823
Funding: “Funding sources: The National Institutes of Health (RR010601; AR007581; AR047838; AR062002; AR063351), the National Space Biomedical Research Institute (NASA contract NCC 9-58).”
Lau AG, Sun J, Hannah WB, Livingston EW, Heymann D, Bateman TA, Monahan PE.
Joint bleeding in factor VIII deficient mice causes an acute loss of trabecular bone and calcification of joint soft tissues which is prevented with aggressive factor replacement. Haemophilia. 2014 Apr 8. [Epub ahead of print]
(PI: A.G. Lau)
Journal Impact Factor: 2.468
Funding: “Baxter Health Care Corporation: Provided Investigator – Initiated Study support to Paul E. Monahan and Ted A. Bateman. NIH: P01 HL112761 – Paul E. Monahan. NIH: 5R01AR059221-02 -Ted A. Bateman. National Space Biomedical Research Institute: PF03003 through NASA NCC 9-58 – Anthony G Lau. Center for the Advancement of Science in Space (CASIS) – Ted A. Bateman.”
Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ.
Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysis.
BMC Musculoskelet Disord. 2014 Apr 9;15:122.
(PI: H.J. Donahue)
Note: Hindlimb unloading study. This article may be obtained online without charge.
Journal Impact Factor: 1.90
Funding: “This work was supported by grant R01 AG013087 from the National Institute on Aging and grant MA02802 from the National Space Biomedical Research Institute.”
Krigsfeld GS, Shah JP, Sanzari JK, Lin L, Kennedy AR.
Biological effects of space radiation and development of effective countermeasures.
Life Sci Space Res. 2014 Oct;3:1-9.
(PI: A.R. Kennedy/Center of Acute Radiation Research)
Journal Impact Factor: 1.183
Funding: “The research was supported by the NSBRI Center of Acute Radiation Research (CARR) grant. The NSBRI is funded through NASA NCC 9-58.”
Olsen RH, Marzulla T, Raber J.
Impairment in extinction of contextual and cued fear following post-training whole-body irradiation.
Front Behav Neurosci. 2014 Jul 2;8:231.
(PIs: J. Raber; G.A. Nelson/NSCOR)
Note: This article may be obtained online without charge.
Journal Impact Factor: 4.76
Funding: “This work was supported by NASA Grants no. NNX10AD59G and NNJ12ZSA001N.”
Berman MI, Buckey JC Jr, Hull JG, Linardatos E, Song SL, McLellan RK, Hegel MT.
Feasibility study of an interactive multimedia electronic problem solving treatment program for depression: A preliminary uncontrolled trial.
Behav Ther. 2014 May;45(3):358-75. Epub 2014 Feb 7.
(PI: J.A. Cartriene for the ePST software used in the study)
Journal Impact Factor: 3.099
Funding: From the Headnote: “We appreciate the National Space Biomedical Research Institute for supporting the development of the ePST™ program through NASA NCC 9-58.” From the Disclosure Statement: “This research was funded by a Dartmouth Center for Clinical and Translational Research SYNERGY Pilot Project Grant awarded to Mark Hegel.”
Pellegrino R, Kavakli IH, Goel N, Cardinale CJ, Dinges DF, Kuna ST, Maislin G, Van Dongen HP, Tufik S, Hogenesch JB, Hakonarson H, Pack AI.
A Novel BHLHE41 variant is associated with short sleep and resistance to sleep deprivation in humans.
(PI: D.F. Dinges)
Journal Impact Factor: 5.051
Funding: “This work was supported in part by NIH grant P01 HL094307 and Institutional Development Fund from the Center for Applied Genomics at The Children’s Hospital of Philadelphia. Data analyzed from experiments on chronic partial sleep deprivation were supported by the National Space Biomedical Research Institute through NASA NCC 9-58, NIH NR004281, CTRC UL1RR024134 and the Department of the Navy, Office of Naval Research Award No. N00014-11-1-0361.”
Dhoble AS, Pullammanappallil PC.
Design and operation of an anaerobic digester for waste management and fuel generation during long term lunar mission.
Adv Space Res. 2014 Jun 30. [In Press]
Journal Impact Factor: 1.238
Funding: “The authors gratefully acknowledge the financial support provided by NASA-Johnson Space Center, Houston, TX, USA for this project under Cooperative Agreement NCC9 -110.”
Other papers of interest:
Gerzer R, White R, Graef P, Coordinators. Other Members: Cohen MM, Davis JR, Demaria-Pesce V, Denise P, Dinges D, Ganse B, Horneck G, Horstman AM, Katuntsev VP, Koch B, Kozlovskaya I, van Loon J, Lindsay K, Mukai C, Orlov O, Li YH, Paloski WH, Pinsky LS, Rittweger J, Russomano T, Shang P, Strollo F, Sundblad P, White O, Wuyts F, Young LR, Zhuang F.
Space medicine and physiology in the exploration era: The Cologne Resolution.
Acta Astronaut. 2014 Jul 22. [In Press]
Note: From the abstract: “The general Content of this Resolution was discussed and agreed at the 19th International Academy of Astronautics Humans in Space Symposium in Cologne, Germany, July 7 to 12, 2013 and finally endorsed by the 392 participants of the Symposium from 26 countries. This resolution thus reflects the opinion of a substantial percentage of the global Space Medicine and Physiology Community.”
Ochiai M, Niu A, Steffens H, Balogh W, Haubold H, Othman M, Doi T.
United Nations Human Space Technology Initiative (HSTI).
Acta Astronaut. 2014 Aug 1. [In Press]
Note: From the abstract: “The Human Space Technology…aims to involve more countries in activities related to human spaceflight and space exploration and to increase the benefits from the outcome of such activities through international cooperation, to make space exploration a truly international effort.”
Salotti J-M, Heidmann R.
Roadmap to a human Mars mission.
Acta Astronaut. 2014 Jul 2. [In Press]
Convertino VA.
Neurohumoral mechanisms associated with orthostasis: Reaffirmation of the significant contribution of the heart rate response.
Front Physiol. 2014 Jun 30;5:236. Review.
Note: This article may be obtained online without charge.
Hinojosa-Laborde C, Ryan KL, Rickards CA, Convertino VA.
Resting sympathetic baroreflex sensitivity in subjects with low and high tolerance to central hypovolemia induced by lower body negative pressure.
Front Physiol. 2014 Jun 30;5:241.
Note: This article may be obtained online without charge.
Kamiya A, Kawada T, Sugimachi M.
Systems physiology of the baroreflex during orthostatic stress: From animals to humans.
Front Physiol. 2014 Jul 8;5:256.
Note: This article may be obtained online without charge.
Seldin MM, Byerly MS, Petersen PS, Swanson R, Balkema-Buschmann A, Groschup MH, Wong GW.
Seasonal oscillation of liver-derived hibernation protein complex in the central nervous system of non-hibernating mammals.
J Exp Biol. 2014 Aug 1;217(Pt 15):2667-79.
Caiani EG, Massabuau P, Weinert L, Vaida P, Lang RM.
Effects of 5-days head-down bed-rest, with and without short arm centrifugation as countermeasure, on cardiac function in males (BR-AG1 Study).
J Appl Physiol (1985). 2014 Jul 31. pii: jap.00122.2014. [Epub ahead of print]
Note: Bed rest study.
Cornachione AS, Cação-Benedini LO, Chesca DL, Martinez EZ, Mattiello-Sverzut AC.
Effects of eccentric exercise in rehabilitation of phasic and tonic muscles after leg immobilization in rats.
Acta Histochem. 2014 Jul 27. pii: S0065-1281(14)00182-2. [Epub ahead of print]
Note: A steel mesh and cotton immobilization device was used.
Can T, Faas L, Ashford DA, Dowle A, Thomas J, O’Toole P, Blanco G.
Proteomic analysis of laser capture microscopy purified myotendinous junction regions from muscle sections.
Proteome Sci. 2014 May 7;12:25.
Note: This article may be obtained online without charge.
Gehlert S, Suhr F, Gutsche K, Willkomm L, Kern J, Jacko D, Knicker A, Schiffer T, Wackerhage H, Bloch W.
High force development augments skeletal muscle signalling in resistance exercise modes equalized for time under tension.
Pflugers Arch. 2014 Jul 29. [Epub ahead of print]
Zhang Y, Wesolowski M, Karakatsani A, Witzemann V, Kröger S.
Formation of cholinergic synapse-like specializations at developing murine muscle spindles.
Dev Biol. 2014 Jul 23. pii: S0012-1606(14)00347-9. [Epub ahead of print]
Kouhnavard M, Nasli Esfahani E, Montazeri M, Hashemian SJ, Mehrazma M, Larijani B, Nezami Asl A, Khoshvaghti A, Falsafi A, Lalehfar K, Malekpour K, Vosugh M.
Effects of vitamin D and calcium supplementation on micro-architectural and densitometric changes of rat femur in a microgravity simulator model.
Iran Red Crescent Med J. 2014 Jun;16(6):e18026. Epub 2014 Jun 5.
Note: Hindlimb unloading study. This article may be obtained online without charge.
Sun, L-W, Huang Y-F, Wang Y, Luan H-Q, Fan Y-B.
Comparison of bone histomorphometry and μCT on evaluating the bone quality in tail-suspended rats.
Life Sci Space Res. 2014 Jul 16. [In Press]
Note: Hindlimb unloading study.
McKenna-Lawlor S, Bhardwaj A, Ferrari F, Kuznetsov N, Lal AK, Li Y, Nagamatsu A, Nymmik R, Panasyuk M, Petrov V, Reitz G, Pinsky L, Shukor SM, Singhvi AK, Straube U, Tomi L, Townsend L.
Feasibility study of astronaut standardized career dose limits in LEO and the outlook for BLEO.
Acta Astronaut. 2014 Jul 17. [In Press]
Note:  From the abstract: “Cosmic Study Group SG3.19/1.10 was established in February 2013 under the aegis of the International Academy of Astronautics to consider and compare the dose limits adopted by various space agencies for astronauts in Low Earth Orbit…The present paper presents preliminary results of the study reported at a Symposium held in Turin by the Academy in July2013.”
Fu Q, Levine BD.
Pathophysiology of neurally mediated syncope: Role of cardiac output and total peripheral resistance.
Auton Neurosci. 2014 Jul 16. pii: S1566-0702(14)00098-8. [Epub ahead of print] Review.
Luebke AE, Holt JC, Jordan PM, Wong YS, Caldwell JS, Cullen KE.
Loss of α-calcitonin gene-related peptide (α-CGRP) reduces the efficacy of the vestibulo-ocular reflex (VOR).
J Neurosci. 2014 Jul 30;34(31):10453-8.
Tanigawa N, Yano S, Higashibata A, Tsuchiya Y, Tanii H, Ando N, Kubota K, Nagase M.
Development and validation of a closed chamber for cell culture experiments in space.
Biol Sci Space. 2014;28:1-5
Note: This article may be obtained online without charge.
Wolff SA, Coelho LH, Karoliussen I, Kittang Jost A-I.
Effects of the extraterrestrial environment on plants: Recommendations for future space experiments for the MELiSSA higher plant compartment.
  1. 2014;4(2):189-204. Review.
Note: This article may be obtained online without charge.
Shklavtsova ES, Ushakova SA, Shikhov VN, Anishchenko OV.
Effects of mineral nutrition conditions on heat tolerance of chufa (Cyperus esculentus L.) plant communities to super optimal air temperatures in the BTLSS.
Adv Space Res. 2014;54:1135-45.
Sathishkumar Y, Velmurugan N, Lee HM, Rajagopal K, Im CK, Lee YS.
Effect of low shear modeled microgravity on phenotypic and central chitin metabolism in the filamentous fungi Aspergillus niger and Penicillium chrysogenum.
Antonie Van Leeuwenhoek. 2014 Aug;106(2):197-209. Epub 2014 May 7.
Miyamoto K, Yamasaki T, Uheda E, Ueda J.
Analysis of apical hook formation in Alaska pea with a 3-D clinostat and agravitropic mutant ageotropum.
Front Plant Sci. 2014 Apr 8;5:137.
Note: This article may be obtained online without charge.
Kittang AI, Iversen TH, Fossum KR, Mazars C, Carnero-Diaz E, Boucheron-Dubuisson E, Le Disquet I, Legué V, Herranz R, Pereda-Loth V, Medina FJ.
Exploration of plant growth and development using the European Modular Cultivation System facility on the International Space Station.
Plant Biol (Stuttg). 2014 May;16(3):528-38. Epub 2014 Jan 17. Review.
Note: ISS results.
Aubry-Hivet D, Nziengui H, Rapp K, Oliveira O, Paponov IA, Li Y, Hauslage J, Vagt N, Braun M, Ditengou FA, Dovzhenko A, Palme K.
Analysis of gene expression during parabolic flights reveals distinct early gravity responses in Arabidopsis roots.
Plant Biol (Stuttg). 2014 Jan;16 Suppl 1:129-41.
Note: Parabolic flight results.
Ruyters G, Braun M.
Plant biology in space: Recent accomplishments and recommendations for future research.
Plant Biol (Stuttg). 2014 Jan;16 Suppl 1:4-11. Review.
Janoštiak R, Pataki AC, Brábek J, Rösel D.
Mechanosensors in integrin signaling: The emerging role of p130Cas.
Eur J Cell Biol. 2014 Jul 9. pii: S0171-9335(14)00067-3. [Epub ahead of print] Review.
D’Angelo G, Rampone S.
Towards a HPC-oriented parallel implementation of a learning algorithm for bioinformatics applications.
BMC Bioinformatics. 2014 May 6;15 Suppl 5:S2. Epub 2014 May 6.
Note: From the abstract: “The great versatility that characterizes it, makes U-BRAIN applicable in many of the fields in which there are data to be analyzed.” This article may be obtained online without charge.

SpaceRef staff editor.