Status Report

NASA Spaceline Current Awareness 6 December 2103 (Recent Space Life Science Research Results)

By SpaceRef Editor

December 6, 2013

Filed under Spaceline, Spaceline Current Awareness, US

Next list: December 20, 2013

Papers deriving from NASA support:

Schmidt MA, Goodwin TJ.

Personalized medicine in human space flight: using Omics based analyses to develop individualized countermeasures that enhance astronaut safety and performance.

http://www.ncbi.nlm.nih.gov/pubmed/24273472

NOTE: This article may be obtained online without charge via PubMed Central or at the publisher’s site: http://link.springer.com/article/10.1007/s11306-013-0556-3

The article appears to be featured on the cover of the journal: http://link.springer.com/journal/11306/9/6/page/1

Meyers VE, García HD, McMullin TS, Tobin JM, James JT.

Safe human exposure limits for airborne linear siloxanes during spaceflight.

Inhal Toxicol. 2013 Nov;25(13):735-46.

http://www.ncbi.nlm.nih.gov/pubmed/24255951

Zanello SB, Theriot CA, Prospero Ponce CM, Chevez-Barrios P.

Spaceflight effects and molecular responses in the mouse eye: Observations after Shuttle Mission STS-133.

Gravit Space Res. 2013 Oct;1(1):29-46.

http://gravitationalandspacebiology.org/index.php/journal/issue/view/49/showToc

(PI: S.B. Zanello)

NOTE: STS-133 results. This article may be obtained online without charge.

This issue of Gravitational and Space Research, with a new volume and issue number, is a new iteration of the journal of the American Society for Gravitational and Space Research. The society and journal have been renamed to reflect the addition of space and gravitational physical sciences research to what had been space and gravitational life sciences research. This article and all of the articles in the issue may be obtained online without charge.

Evans JM, Mohney L, Wang S, Moore RK, Elayi SC, Stenger MB, Moore FB, Knapp CF.

Cardiovascular regulation during body unweighting by lower body positive pressure.

Aviat Space Environ Med. 2013 Nov;84(11):1140-6.

http://www.ncbi.nlm.nih.gov/pubmed/24279226

Sung M, Li J, Spieker AJ, Spatz J, Ellman R, Ferguson VL, Bateman TA, Rosen GD, Bouxsein M, Rutkove SB.

Spaceflight and hind limb unloading induce similar changes in electrical impedance characteristics of mouse gastrocnemius muscle.

J Musculoskelet Neuronal Interact. 2013 Dec;13(4):405-11.

http://www.ncbi.nlm.nih.gov/pubmed/24292610

(PIs: M. Bouxsein, T.A. Bateman)

NOTE: STS-135 results. This article may be obtained online without charge: http://www.ismni.org/jmni/pdf/54/02SUNG.pdf

Ellman R, Grasso DJ, van Vliet M, Brooks DJ, Spatz JM, Conlon C, Bouxsein ML.

Combined effects of botulinum toxin injection and hind limb unloading on bone and muscle.

Calcif Tissue Int. 2013 Nov 17. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24240478

(PIs: M.L. Bouxsein; NSBRI?; R. Ellman, NASA Harriet G. Jenkins Predoctoral Fellowship)

Lloyd SA, Ferguson VS, Simske SJ, Dunlap AW, Livingston EW, Bateman TA.

Housing in the Animal Enclosure Module spaceflight hardware increases trabecular bone mass in ground-control mice.

Gravit Space Res. 2013 Oct;1(1):2-19.

http://gravitationalandspacebiology.org/index.php/journal/issue/view/49/showToc

(PI: T.A. Bateman)

NOTE: The mice used in this experiment were the ground control for an STS-108 experiment.

Chowdhury P, Long A, Harris G, Soulsby ME, Dobretsov M.

Animal model of simulated microgravity: A comparative study of hindlimb unloading via tail versus pelvic suspension.

Physiol Rep. 2013 Jun;1(1):e00012. Epub 2013 Jun 12.

http://www.ncbi.nlm.nih.gov/pubmed/24303103

NOTE: This article may be obtained online without charge: http://onlinelibrary.wiley.com/doi/10.1002/phy2.12/abstract

Cavanagh PR, Rice AJ, Licata AA, Kuklis MM, Novotny SC, Genc KO, Englehaupt RK, Hanson AM.

A novel lunar bed rest analogue.

Aviat Space Environ Med. 2013 Nov;84(11):1191-5.

http://www.ncbi.nlm.nih.gov/pubmed/24279234

Shymon SJ, Yaszay B, Dwek JR, Proudfoot JA, Donohue M, Hargens AR.

Altered disc compression in children with idiopathic low back pain: An upright MRI backpack study.

Spine (Phila Pa 1976). 2013 Nov 18. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24253789

(PI: A.R. Hargens)

Hammond TG, Stodieck L, Birdsall HH, Becker JL, Koenig P, Hammond JS, Gunter MA, Allen PL.

Effects of microgravity on the virulence of Listeria monocytogenes, Enterococcus faecalis, Candida albicans, and methicillin-resistant Staphylococcus aureus.

http://www.ncbi.nlm.nih.gov/pubmed/24283929

(PI: T.G. Hammond)

NOTE: ISS results.

Saha J, Wang M, Cucinotta FA.

Investigation of switch from ATM to ATR signaling at the sites of DNA damage induced by low and high LET radiation.

DNA Repair (Amst). 2013 Dec;12(12):1143-51. Epub 2013 Nov 12.

http://www.ncbi.nlm.nih.gov/pubmed/24238855

(PI: F.A. Cucinotta)

Hu S, Cucinotta FA.

Epidermal homeostasis and radiation responses in a multiscale tissue modeling framework.

Integr Biol (Camb). 2013 Nov 25. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24270511

(PI: F.A. Cucinotta)

Sanzari JK, Wan XS, Krigsfeld GS, Wroe AJ, Gridley DS, Kennedy AR.

The effects of gamma and proton radiation exposure on hematopoietic cell counts in the ferret model.

Gravit Space Res. 2013 Oct;1(1):79-94.

http://gravitationalandspacebiology.org/index.php/journal/issue/view/49/showToc

(PI: A.R. Kennedy/Center of Acute Radiation Research)

NOTE: This article may be obtained online without charge.

Hlatky L, Hahnfeldt P.

Beyond the cancer cell: Progression-level determinants highlight the multi-scale nature of carcinogenesis risk.

Cancer Res. 2013 Nov 27. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24272486

(PI: L. Hlatky)

Dynlacht JR.

The role of age, sex and steroid sex hormones in radiation cataractogenesis.

Radiat Res. 2013 Nov 21. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24261552

(PI: J.R. Dynlacht)

Grant JL, Fishbein MC, Hong LS, Krysan K, Minna JD, Shay JW, Walser TC, Dubinett SM.

A novel molecular pathway for Snail-dependent, SPARC-mediated invasion in non-small cell lung cancer pathogenesis.

Cancer Prev Res (Phila). 2013 Nov 19. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24253315

(PIs: J.D. Minna/J.W. Shay/NSCOR)

Forsman AD, Nier HA.

The effects of spaceflight on mucin production in the mouse uterus.

Gravit Space Res. 2013 Oct;1(1):20-8.

http://gravitationalandspacebiology.org/index.php/journal/issue/view/49/showToc

NOTE: STS-118 results. This article may be obtained online without charge.

Benjaminson MA, Gilchriest JA, Lehrer S.

Development in altered gravity influences height in Dictyostelium.

Gravit Space Res. 2013 Oct;1(1):51-8.

http://gravitationalandspacebiology.org/index.php/journal/issue/view/49/showToc

(PI: M.A. Benjaminson)

NOTE: This article may be obtained online without charge.

Ronca AE, Alwood JS, Globus RK, Souza KA.

Mammalian reproduction and development on the International Space Station (ISS): Proceedings of the Rodent Mark III Habitat Workshop.

Gravit Space Res. 2013 Oct;1(1):107-23.

http://gravitationalandspacebiology.org/index.php/journal/issue/view/49/showToc

NOTE: This article may be obtained online without charge.

Denison FC, Gökirmak T, Ferl RJ.

Phosphorylation-related modification at the dimer interface of 14-3-3ω dramatically alters monomer interaction dynamics.

Arch Biochem Biophys. 2013 Nov 5;541C:1-12. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24211434

(PI: R.J. Ferl)

Massa G, Newsham G, Hummerick ME, Caro JL, Stutte GW, Morrow RC, Wheeler RM.

Preliminary species and media selection for the Veggie space hardware.

Gravit Space Res. 2013 Oct;1(1):95-106.

http://gravitationalandspacebiology.org/index.php/journal/issue/view/49/showToc

NOTE: This article may be obtained online without charge.

Other papers of interest:

Arai T, Limper U, Gauger P, Beck L.

Pulse contour methods to estimate cardiovascular indices in micro- and hypergravity.

Aviat Space Environ Med. 2013 Nov;84(11):1178-85.

http://www.ncbi.nlm.nih.gov/pubmed/24279232

NOTE: Parabolic flight results.

Morel JL, Dabertrand F, Porte Y, Prevot A, Macrez N.

Up-regulation of ryanodine receptor expression increases the calcium-induced calcium release and spontaneous calcium signals in cerebral arteries from hindlimb unloaded rats.

Pflugers Arch. 2013 Nov 15. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24233561

Tseng L, Tang SC, Chang CY, Lin YC, Abbod MF, Shieh JS.

Nonlinear and conventional biosignal analyses applied to tilt table test for evaluating autonomic nervous system and autoregulation.

Open Biomed Eng J. 2013 Sep 6;7:93-9.

http://www.ncbi.nlm.nih.gov/pubmed/24222803

NOTE: This article may be obtained online without charge via PubMed Central or at the publisher’s site: http://dx.doi.org/10.2174/1874120720130905004

Robbins D, Yoganathan P, Goss-Sampson M.

The influence of whole body vibration on the central and peripheral cardiovascular system.

Clin Physiol Funct Imaging. 2013 Nov 17. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24237890

Kim HA, Yi HA, Lee H.

Spectrum of autonomic dysfunction in orthostatic dizziness.

Clin Neurophysiol. 2013 Nov 5. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24268815

Ono K, Kuniyoshi H, Tanigaki Y.

Effects of underwater arm-cranking exercise on cardiac autonomic nervous activity.

Gravit Space Res. 2013 Oct;1(1):47-50.

http://gravitationalandspacebiology.org/index.php/journal/issue/view/49/showToc

NOTE: This article may be obtained online without charge.

Fleischman D, Allingham RR.

The role of cerebrospinal fluid pressure in glaucoma and other ophthalmic diseases: A review.

Saudi J Ophthalmol. 2013 Apr;27(2):97-106. Epub 2013 Mar 17.

http://www.ncbi.nlm.nih.gov/pubmed/24227969

NOTE: This article has a short section on this topic as applied to microgravity; these authors have previously written about this subject. The article may be obtained online without charge via PubMed Central or at the publisher’s site: http://www.sciencedirect.com/science/article/pii/S1319453413000283

Yang Z, Fei J, Song D, Zhao Y, Yu J, Yu X.

Effects of simulated natural air movement on thermoregulatory response during head-down bed rest.

J Therm Biol. 2013 Oct;38(7):363-8.

http://dx.doi.org/10.1016/j.jtherbio.2013.04.006

NOTE: Bed rest study.

Crookham J.

A guide to exercise prescription.

Prim Care. 2013 Dec;40(4):801-20.

http://www.ncbi.nlm.nih.gov/pubmed/24209719

NOTE: This article and the following article are examples of articles that suggest that physical activity/exercise should be prescribed or directed by physicians as part of medical care.

Taylor D.

Physical activity is medicine for older adults.

Postgrad Med J. 2013 Nov 19. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24255119

NOTE: This article may be obtained online without charge.

Asmaro D, Mayall J, Ferguson S.

Cognition at altitude: Impairment in executive and memory processes under hypoxic conditions.

Aviat Space Environ Med. 2013 Nov;84(11):1159-65.

http://www.ncbi.nlm.nih.gov/pubmed/24279229

Mardanov AV, Babykin MM, Beletsky AV, Grigoriev AI, Zinchenko VV, Kadnikov VV, Kirpichnikov MP, Mazur AM, Nedoluzhko AV, Novikova ND, Prokhortchouk EB, Ravin NV, Skryabin KG, Shestakov SV.

Metagenomic analysis of the dynamic changes in the gut microbiome of the participants of the MARS-500 experiment, simulating long term space flight.

Acta Naturae. 2013 Jul;5(3):116-25.

http://www.ncbi.nlm.nih.gov/pubmed/24303207

NOTE: This article may be obtained online without charge. Click on the article title (find the issue if a different issue appears), then scroll to and open the pdf, which is the pdf for the entire issue: http://actanaturae.ru/

Fardo F, Spironelli C, Angrilli A.

Horizontal body position reduces cortical pain-related processing: Evidence from late ERPs.

PLoS One. 2013 Nov 20;8(11):e81964.

http://www.ncbi.nlm.nih.gov/pubmed/24278467

NOTE: Short-term bed rest study. This article may be obtained online without charge.

Iwata C, Abe C, Nakamura M, Morita H.

Hypergravity exposure for 14 days increases the effects of propofol in rats.

Anesth Analg. 2013 Nov 15. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24247228

Stoupel EG.

Gene functional dynamics: Environment as a trigger?

J Basic Clin Physiol Pharmacol. 2013 Nov 21:1-4. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24259246

Sawai T, Uzuki M, Miura Y, Kamataki A, Matsumura T, Saito K, Kurose A, Osamura YR, Yoshimi N, Kanno H, Moriya T, Ishida Y, Satoh Y, Nakao M, Ogawa E, Matsuo S, Kasai H, Kumagai K, Motoda T, Hopson N.

World’s first telepathology experiments employing WINDS ultra-high-speed internet satellite, nicknamed “KIZUNA”.

J Pathol Inform. 2013 Sep 27;4:24.

http://www.ncbi.nlm.nih.gov/pubmed/24244882

NOTE: This article may be obtained online without charge via PubMed Central or at the publisher’s site: http://dx.doi.org/10.4103/2153-3539.119002

Calhoun J, Savoie C, Randolph-Gips M, Bozkurt I.

Human reliability analysis in spaceflight applications.

Qual Reliabil Eng Int. 2013 Oct;29(6):869-82.

http://dx.doi.org/10.1002/qre.1442

Calhoun J, Savoie C, Randolph-Gips M, Bozkurt I.

Human reliability analysis in spaceflight applications, Part 2: Modified CREAM for spaceflight.

Qual Reliabil Eng Int. 2013 Jan 29. [Epub ahead of print]

http://dx.doi.org/10.1002/qre.1471

Macilwain C.

Thrill of space exploration is a universal constant.

http://www.ncbi.nlm.nih.gov/pubmed/24256771

NOTE: This article, well worth reading, may be obtained online without charge. Also see: http://www.nature.com/news/space-spectacular-1.14201

Salanova M, Schiffl G, Gutsmann M, Felsenberg D, Furlan S, Volpe P, Clarke A, Blottner D.

Nitrosative stress in human skeletal muscle attenuated by exercise countermeasure after chronic disuse.

Redox Biol. 2013 Oct 28;1(1):514-26.

http://www.ncbi.nlm.nih.gov/pubmed/24251120

NOTE: Second Berlin Bed Rest Study. This article may be obtained online without charge via PubMed Central or at the publisher’s site:http://www.sciencedirect.com/science/article/pii/S221323171300075X

Garton FC, Seto JT, Quinlan KG, Yang N, Houweling PJ, North KN.

α-Actinin-3 deficiency alters muscle adaptation in response to denervation and immobilization.

Hum Mol Genet. 2013 Nov 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24234654

Snijders T, Wall BT, Dirks ML, Senden JM, Hartgens F, Dolmans J, Losen M, Verdijk LB, van Loon LJ.

Muscle disuse atrophy is not accompanied by changes in skeletal muscle satellite cell content.

Clin Sci (Lond). 2013 Nov 12. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24215591

Dirks ML, Wall BT, Snijders T, Ottenbros CL, Verdijk LB, van Loon LJ.

Neuromuscular electrical stimulation prevents muscle disuse atrophy during leg immobilisation in humans.

Acta Physiol (Oxf). 2013 Nov 20. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24251881

Boesen AP, Dideriksen KJ, Couppe C, Magnusson SP, Schjerling P, Boesen M, Aagaard P, Kjaer M, Langberg H.

Effect of growth hormone on aging connective tissue in muscle and tendon – gene expression, morphology and function following immobilization and rehabilitation.

J Appl Physiol (1985). 2013 Nov 14. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24235105

Sieck GC, Ferreira LF, Reid MB, Mantilla CB.

Mechanical properties of respiratory muscles.

Compr Physiol. 2013 Oct 1;3(4):1553-67.

http://www.ncbi.nlm.nih.gov/pubmed/24265238

Reidy PT, Hinkley JM, Trappe TA, Trappe SW, Harber MP.

Protein composition of endurance trained human skeletal muscle.

Int J Sports Med. 2013 Nov 14. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24234010

Paddon-Jones D, Leidy H.

Dietary protein and muscle in older persons.

Curr Opin Clin Nutr Metab Care. 2013 Jan;17(1):5-11.

http://www.ncbi.nlm.nih.gov/pubmed/24241130

NOTE: This article is in a section on Aging: Biology and Nutrition (click on issue): http://journals.lww.com/co-clinicalnutrition/Abstract/2014/01000/Dietary_protein_and_muscle_in_older_persons.3.aspx

Senf SM.

Skeletal muscle heat shock protein 70: Diverse functions and therapeutic potential for wasting disorders.

Front Physiol. 2013 Nov 11;4:330.

http://www.ncbi.nlm.nih.gov/pubmed/24273516

NOTE: This article may be obtained online without charge.

Wakabayashi H, Sakuma K.

Comprehensive approach to sarcopenia treatment.

Curr Clin Pharmacol. 2013 Nov 11. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24219006

Biryukov NS, Ogneva IV.

Interaction between muscle cell and external mechanical field: A model study.

http://dx.doi.org/10.1134/S0006350913030044

This paper is a translation in English of the Russian original published in Biofizika. 2013 May-Jun;58(3):531-9: http://www.ncbi.nlm.nih.gov/pubmed/24159824

Li CR, Zhang GW, Niu YB, Pan YL, Zhai YK, Mei QB.

Antiosteoporosis effect of Radix Scutellariae extract on density and microstructure of long bones in tail-suspended Sprague-Dawley rats.

Evid Based Complement Alternat Med. 2013;2013:753703. Epub 2013 Oct 9.

http://www.ncbi.nlm.nih.gov/pubmed/24223617

NOTE: This article may be obtained online without charge.

Zahoor M, Cha PH, Min DS, Choi KY.

Indirubin-3′-oxime reverses bone loss in ovariectomized, hindlimb-unloaded mice via activation of the Wnt/β-catenin signaling.

J Bone Miner Res. 2013 Nov 16. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24243753

Shang P, Zhang J, Qian A, Li J, Meng R, Di S, Hu L, Gu Z.

Bone cells under microgravity.

J Mech Med Biol. 2013 Oct;13(5):1340006.

http://dx.doi.org/10.1142/S021951941340006X

Klika V, Pérez MA, García-Aznar JM, Maršík F, Doblaré M.

A coupled mechano-biochemical model for bone adaptation.

J Math Biol. 2013 Nov 12. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24212399

Reijnders CM, van Essen HW, van Rens BT, van Beek JH, Ylstra B, Blankenstein MA, Lips P, Bravenboer N.

Increased expression of matrix extracellular phosphoglycoprotein (MEPE) in cortical bone of the rat tibia after mechanical loading: Identification by oligonucleotide microarray.

PLoS One. 2013 Nov 8;8(11):e79672.

http://www.ncbi.nlm.nih.gov/pubmed/24255709

NOTE: This article may be obtained online without charge.

Aleshcheva G, Sahana J, Ma X, Hauslage J, Hemmersbach R, Egli M, Infanger M, Bauer J, Grimm D.

Changes in morphology, gene expression and protein content in chondrocytes cultured on a Random Positioning Machine.

PLoS One. 2013 Nov 11;8(11):e79057.

http://www.ncbi.nlm.nih.gov/pubmed/24244418

NOTE: This article may be obtained online without charge.

Lee KL, Hoey DA, Spasic M, Tang T, Hammond HK, Jacobs CR.

Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo.

FASEB J. 2013 Nov 25. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24277577

Loiselle AE, Lloyd SA, Paul EM, Lewis GS, Donahue HJ.

Inhibition of GSK-3β rescues the impairments in bone formation and mechanical properties associated with fracture healing in osteoblast selective connexin 43 deficient mice.

PLoS One. 2013 Nov 8;8(11):e81399.

http://www.ncbi.nlm.nih.gov/pubmed/24260576

NOTE: This article may be obtained online without charge.

Mendy A, Vieira ER, Albatineh AN, Nnadi AK, Lowry D, Gasana J.

Low bone mineral density is associated with balance and hearing impairments.

Ann Epidemiol. 2013 Oct 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24263001

Juffer P, Jaspers RT, Klein-Nulend J, Bakker AD.

Mechanically loaded myotubes affect osteoclast formation.

Calcif Tissue Int. 2013 Nov 22. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24264813

Sondag GR, Salihoglu S, Lababidi SL, Crowder DC, Moussa FM, Abdelmagid SM, Safadi FF.

Osteoactivin induces transdifferentiation of C2C12 myoblasts into osteoblasts.

J Cell Physiol. 2013 Nov 22. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24265122

Berger T, Bilski P, Hajek M, Puchalska M, Reitz G.

The MATROSHKA experiment: Results and comparison from extravehicular activity (MTR-1) and intravehicular activity (MTR-2A/2B) exposure.

Radiat Res. 2013 Nov 19. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24252101

NOTE: ISS results.

Hu Y, Hellweg CE, Baumstark-Khan C, Reitz G, Lau P.

Cell cycle delay in murine pre-osteoblasts is more pronounced after exposure to high-LET compared to low-LET radiation.

Radiat Environ Biophys. 2013 Nov 16. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24240273

Hu Y, Ru N, Xiao H, Chaturbedi A, Hoa NT, Tian XJ, Zhang H, Ke C, Yan F, Nelson J, Li Z, Gramer R, Yu L, Siegel E, Zhang X, Jia Z, Jadus MR, Limoli CL, Linskey ME, Xing J, Zhou YH.

Tumor-specific chromosome mis-segregation controls cancer plasticity by maintaining tumor heterogeneity.

PLoS One. 2013 Nov 25;8(11):e80898.

http://www.ncbi.nlm.nih.gov/pubmed/24282558

NOTE: From abstract: “Overall, our findings show, for the first time, the involvement of chromosome instability in maintaining tumor heterogeneity, which underlies the enhanced growth, persistence and treatment resistance of cancers.” This article may be obtained online without charge.

Tommasino F, Friedrich T, Scholz U, Taucher-Scholz G, Durante M, Scholz M.

A DNA double-strand break kinetic rejoining model based on the local effect model.

Radiat Res. 2013 Nov;180(5):524-38. Epub 2013 Oct 21.

http://www.ncbi.nlm.nih.gov/pubmed/24138482

Heuskin AC, Wéra AC, Riquier H, Michiels C, Lucas S.

Low-dose hypersensitivity and bystander effect are not mutually exclusive in A549 lung carcinoma cells after irradiation with charged particles.

Radiat Res. 2013 Nov;180(5):491-8. Epub 2013 Oct 14.

http://www.ncbi.nlm.nih.gov/pubmed/24125486

Oliai C, Yang LX.

Radioprotectants to reduce the risk of radiation-induced carcinogenesis.

Int J Radiat Biol. 2013 Nov 14. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24164532

Kim KS, Kim JE, Choi KJ, Bae S, Kim DH.

Characterization of DNA damage-induced cellular senescence by ionizing radiation in endothelial cells.

Int J Radiat Biol. 2013 Oct 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24164458

Šimeček M, Šikl R.

[Long-term group isolation and its influence on visual perception: Results of Mars-500 project]

Československá psychologie. 2013;57(4):342-57. Czech.

http://cspsych.psu.cas.cz/result.php?from=811&to=811

Tribukait A, Bergsten E, Eiken O.

Variability in perceived tilt during a roll plane canal-otolith conflict in a gondola centrifuge.

Aviat Space Environ Med. 2013 Nov;84(11):1131-9.

http://www.ncbi.nlm.nih.gov/pubmed/24279225

Kryskow MA, Beidleman BA, Fulco CS, Muza SR.

Performance during simple and complex military psychomotor tasks at various altitudes.

Aviat Space Environ Med. 2013 Nov;84(11):1147-52.

http://www.ncbi.nlm.nih.gov/pubmed/24279227

Cheung B.

Spatial disorientation: More than just illusion.

Aviat Space Environ Med. 2013 Nov;84(11):1211-4.

http://www.ncbi.nlm.nih.gov/pubmed/24279238

Crane BT.

Human visual and vestibular heading perception in the vertical planes.

J Assoc Res Otolaryngol. 2013 Nov 19. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24249574

Chen X, DeAngelis GC, Angelaki DE.

Diverse spatial reference frames of vestibular signals in parietal cortex.

http://www.ncbi.nlm.nih.gov/pubmed/24239126

NOTE: This article may be obtained online without charge.

Berlin JC, Kirk EC, Rowe TB.

Functional implications of ubiquitous semicircular canal non-orthogonality in mammals.

PLoS One. 2013 Nov 19;8(11):e79585.

http://www.ncbi.nlm.nih.gov/pubmed/24260256

NOTE: This article may be obtained online without charge.

Bourrelly A, Vercher JL, Bringoux L.

To pass or not to pass: More a question of body orientation than visual cues.

Q J Exp Psychol (Hove). 2013 Nov 14. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24224565

Zemková E, Hamar D.

Physiological mechanisms of post-exercise balance impairment.

Sports Med. 2013 Nov 22. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24264058

Koslucher FC, Haaland EJ, Stoffregen TA.

Body load and the postural precursors of motion sickness.

Gait Posture. 2014 Jan;39(1):606-10. Epub 2013 Oct 5.

http://www.ncbi.nlm.nih.gov/pubmed/24269524

Cushman JD, Aharoni DB, Willers B, Ravassard P, Kees A, Vuong C, Popeney B, Arisaka K, Mehta MR.

Multisensory control of multimodal behavior: Do the legs know what the tongue is doing?

PLoS One. 2013 Nov 4;8(11):e80465.

http://www.ncbi.nlm.nih.gov/pubmed/24224054

NOTE: This article may be obtained online without charge.

Pomper JK, Gebert L, Fischer M, Bunjes F, Thier P.

Does chronic idiopathic dizziness reflect an impairment of sensory predictions of self-motion?

Front Neurol. 2013 Nov 8;4:181.

http://www.ncbi.nlm.nih.gov/pubmed/24265626

NOTE: This article may be obtained online without charge.

Šolcová I, Gushin V, Vinokhodova A, Lukavský J.

Emotional energy, work self-efficacy, and perceived similarity during the Mars 520 study.

Aviat Space Environ Med. 2013 Nov;84(11):1186-90.

http://www.ncbi.nlm.nih.gov/pubmed/24279233

Santhi N, Groeger JA, Archer SN, Gimenez M, Schlangen LJ, Dijk DJ.

Morning sleep inertia in alertness and performance: Effect of cognitive domain and white light conditions.

PLoS One. 2013 Nov 18;8(11):e79688.

http://www.ncbi.nlm.nih.gov/pubmed/24260280

NOTE: This article may be obtained online without charge.

Vorselen D, Roos WH, MacKintosh FC, Wuite GJ, van Loon JJ.

The role of the cytoskeleton in sensing changes in gravity by nonspecialized cells.

FASEB J. 2013 Nov 21. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/24249634

Haranas I, Gkigkitis I, Zouganelis GD.

A computational study of the mechanics of gravity-induced torque on cells.

Gravit Space Res. 2013 Oct;1(1):59-78.

http://gravitationalandspacebiology.org/index.php/journal/issue/view/49/showToc

NOTE: This article may be obtained online without charge.

Carruthers CW Jr, Gerdts C, Johnson MD, Webb P.

A microfluidic, high throughput protein crystal growth method for microgravity.

PLoS One. 2013 Nov 21;8(11):e82298.

http://www.ncbi.nlm.nih.gov/pubmed/24278480

NOTE: ISS results. This article may be obtained online without charge.

Campbell AI, Ebbens SJ.

Gravitaxis in spherical Janus swimming devices.

http://www.ncbi.nlm.nih.gov/pubmed/24134682

Seong J, Tajik A, Sun J, Guan JL, Humphries MJ, Craig SE, Shekaran A, García AJ, Lu S, Lin MZ, Wang N, Wang Y.

Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19372-7. Epub 2013 Nov 12.

http://www.ncbi.nlm.nih.gov/pubmed/24222685

Romet-Lemonne G, Jégou A.

Mechanotransduction down to individual actin filaments.

Eur J Cell Biol. 2013 Oct-Nov;92(10-11):333-8. Epub 2013 Nov 4.

http://www.ncbi.nlm.nih.gov/pubmed/24252518

NOTE: This article is in an issue on the topic: Actin Dynamics–Part 1.

Li X, Yang X, Wu HX.

Transcriptome profiling of radiata pine branches reveals new insights into reaction wood formation with implications in plant gravitropism.

BMC Genomics. 2013 Nov 8;14:768.

http://www.ncbi.nlm.nih.gov/pubmed/24209714

NOTE: This article may be obtained online without charge.

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