Status Report

NASA Spaceline Current Awareness 4 November 2011 (Recent Space Life Science Research Results)

By SpaceRef Editor
November 4, 2011
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NASA Spaceline Current Awareness 4 November 2011 (Recent Space Life Science Research Results)

Papers deriving from NASA support:

Smith SM, Heer M, Wang Z, Huntoon CL, Zwart SR.
Long-duration space flight and bed rest effects on testosterone and other steroids.
J Clin Endocrinol Metab. 2011 Nov 2. [Epub ahead of print]
(PI: S.M. Smith, C.L. Huntoon)
NOTE: ISS, Shuttle, Skylab, bed rest results.

Dyckman DJ, Sauder CL, Ray CA.
Effects of short term and prolonged bed rest on the vestibulosympathetic reflex.
Am J Physiol Heart Circ Physiol. 2011 Oct 21. [Epub ahead of print]
(PI: C.A. Ray)
NOTE: Bed rest studies (short term study conducted at M.S. Hershey Medical Center, Hershey, PA; long term study at U. Texas Medical Branch Flight Analogs Research Center, Galveston, TX).

Cheng J, Serra-Hsu F, Tian Y, Lin W, Qin YX.
Effects of phase cancellation and receiver aperture size on broadband ultrasonic attenuation for trabecular bone in vitro.
Ultrasound Med Biol. 2011 Oct 26. [Epub ahead of print]
(PI: Y.X. Qin)

Mujoo K, Krumenacker JS, Murad F.
Nitric oxide-cyclic GMP signaling in stem cell differentiation.
Free Radic Biol Med. 2011 Oct 5. [Epub ahead of print]
(PI: F. Murad)

Gridley DS, Pecaut MJ, Green LM, Sanchez MC, Kadhim MA.
Strain-related differences and radiation quality effects on mouse leukocytes: Gamma-rays and protons (with and without aluminum shielding).
In Vivo. 2011 Nov-Dec;25(6):871-80.

Pecaut MJ, Gridley DS.
Impact of head-only iron ion radiation on the peripheral LPS response.
In Vivo. 2011 Nov-Dec;25(6):903-16.

Fernandez-Varea JM, Segui S, Dingfelder M.
L, L, and L x-ray production cross sections of Hf, Ta, W, Re, Os, Au, Pb, and Bi by electron impact: Comparison of distorted-wave calculations with experiment.
Phys Rev A. 2011 Feb;83(2):022702.
(PI: M. Dingfelder)

He Z, Zhang Y, Mehta SK, Pierson DL, Wu H, Rohde LH.
Expression profile of apoptosis related genes and radio-sensitivity of prostate cancer cells.
J Radiat Res (Tokyo). 2011 Oct 22. [Epub ahead of print]
NOTE: This article may be obtained online without charge.

Wood SJ, Loehr JA, Guilliams ME.
Sensorimotor reconditioning during and after spaceflight.
NeuroRehabilitation. 2011;29(2):185-95.
NOTE: ISS results. This article describes the decline in sensorimotor function that occurs during space flight, and countermeasures being employed to counteract this decline on ISS and postflight. The article appears in an issue on the topic of vestibular rehabilitation therapies.

Goel N, Dinges DF.
Behavioral and genetic markers of sleepiness.
J Clin Sleep Med. 2011 Oct 15;7(5 Suppl):S19-21.
(PI: D.F. Dinges)
NOTE: This article is one of a number of articles in this issue on the topic: “Finding a research path for the indentification of biomarkers of sleepiness.” The articles derive from a conference of the same title. Publisher’s site: Go to Supplementary Articles (find the issue if necessary).

Stolc V, Shmygelska A, Griko Y.
Adaptation of organisms by resonance of RNA transcription with the cellular redox cycle.
PLoS One. 2011;6(9):e25270. Epub 2011 Sep 28.
NOTE: This article may be obtained online without charge.

Tsou PL, Lee SY, Allen NS, Winter-Sederoff H, Robertson D.
An ER-targeted calcium-binding peptide confers salt and drought tolerance mediated by CIPK6 in Arabidopsis.
Planta. 2011 Oct 5. [Epub ahead of print]
(PI: C. Brown/N.S. Allen/D. Robertson/NSCORT)

Tavana M, Hatami-Marbini A.
A group AHP-TOPSIS framework for human spaceflight mission planning at NASA.
Expert Syst Applic. 2011 Oct;38(11):13588-603.

Other papers of interest:

Iwasaki KI, Ogawa Y, Aoki K, Yanagida R.
Cerebral circulation during mild +Gz hypergravity by short-arm human centrifuge.
J Appl Physiol. 2011 Nov 3. [Epub ahead of print]…

Zhang R, Ran HH, Ma J, Bai YG, Lin LJ.
NAD(P)H oxidase inhibiting with apocynin improved vascular reactivity in tail-suspended hindlimb unweighting rat.
J Physiol Biochem. 2011 Oct 21. [Epub ahead of print]

Voichanski S, Grossman C, Leibowitz A, Peleg E, Koren-Morag N, Sharabi Y, Shamiss A, Grossman E.
Orthostatic hypotension is associated with nocturnal change in systolic blood pressure.
Am J Hypertens. 2011 Oct 20. [Epub ahead of print]

Perlmuter LC, Sarda G, Casavant V, O’Hara K, Hindes M, Knott PT, Mosnaim AD.
A review of orthostatic blood pressure regulation and its association with mood and cognition.
Clin Auton Res. 2011 Sep 25. [Epub ahead of print]

Moon J, Shim J, Park JH, Hwang HJ, Joung B, Ha JW, Lee MH, Pak HN.
Small left atrial volume is an independent predictor for fainting during head-up tilt test: The impact of intracardiac volume reserve in vasovagal syncope.
Int J Cardiol. 2011 Oct 13. [Epub ahead of print]

Cui J, Leuenberger UA, Gao Z, Sinoway LI.
Sympathetic and cardiovascular responses to venous distension in an occluded limb.
Am J Physiol Regul Integr Comp Physiol. 2011 Sep 21. [Epub ahead of print]

Grosse J, Wehland M, Pietsch J, Ma X, Ulbrich C, Schulz H, Saar K, Huebner N, Hauslage J, Hemmersbach R, Braun M, van Loon J, Vagt N, Infanger M, Eilles C, Egli M, Richter P, Baltz T, Einspanier R, Sharbati S, Grimm D.
Short-term weightlessness produced by parabolic flight maneuvers altered gene expression patterns in human endothelial cells.
FASEB J. 2011 Oct 24. [Epub ahead of print]
NOTE: Parabolic flight results.

Johnson BD, Mather KJ, Wallace JP.
Mechanotransduction of shear in the endothelium: Basic studies and clinical implications.
Vasc Med. 2011 Oct;16(5):365-77.

Blatteau JE, Hugon J, Gempp E, Castagna O, Peny C, Vallee N.
Oxygen breathing or recompression during decompression from nitrox dives with a rebreather: Effects on intravascular bubble burden and ramifications for decompression profiles.
Eur J Appl Physiol. 2011 Oct 14. [Epub ahead of print]

Belav DL, Wilson SJ, Armbrecht G, Rittweger J, Felsenberg D, Richardson CA.
Resistive vibration exercise during bed-rest reduces motor control changes in the lumbo-pelvic musculature.
J Electromyogr Kinesiol. 2011 Oct 19. [Epub ahead of print]
NOTE: Berlin Bed Rest Study.

Fujita N, Murakami S, Fujino H.
The combined effect of electrical stimulation and high-load isometric contraction on protein degradation pathways in muscle atrophy induced by hindlimb unloading.
J Biomed Biotechnol. 2011;2011:401493. Epub 2011 Oct 5.
NOTE: This article may be obtained online without charge via PubMed Central or at the publisher’s site:

Kawano F, Fujita R, Nakai N, Terada M, Ohira T, Ohira Y.
HSP25 can modulate myofibrillar desmin cytoskeleton following the phosphorylation at Ser15 in rat soleus muscle.
J Appl Physiol. 2011 Oct 13. [Epub ahead of print]

Lang TF.
The bone-muscle relationship in men and women.
J Osteoporos. 2011;2011:702735. Epub 2011 Oct 5.
NOTE: This article may be obtained online without charge via PubMed Central or at the publisher’s site:

Eliasson P, Andersson T, Aspenberg P.
Influence of a single loading episode on gene expression in healing rat Achilles tendons.
J Appl Physiol. 2011 Oct 13. [Epub ahead of print]

Morse LR, Sudhakar S, Danilack V, Tun C, Lazzari A, Gagnon DR, Garshick E, Battaglino RA.
Association between sclerostin and bone density in chronic SCI.
J Bone Miner Res. 2011 Oct 17. [Epub ahead of print]

Ishihara A, Nagatomo F, Fujino H, Kondo H, Nojima K.
A threshold dose of heavy ion radiation that decreases the oxidative enzyme activity of spinal motoneurons in rats.
Neurochem Res. 2011 Oct 21. [Epub ahead of print]

Chen Y, Chen X, Li Y, Zhang H, Xie Y, Zhang X, Ren H, Wang Y, Liao S, He M, Ren J, Zhang J, Zhou X, Zheng T, Kilfoy BA, Zhang Y.
Early effects of low dose 12C6+ ion or X-ray irradiation on peripheral blood lymphocytes of patients with alimentary tract cancer.
Dose Response. 2011;9(3):356-68. Epub 2010 Aug 2.
NOTE: This article may be obtained online without charge via PubMed Central or at the publisher’s site:

Moyers MF, Vatnitsky AS, Vatnitsky SM.
Factors for converting dose measured in polystyrene phantoms to dose reported in water phantoms for incident proton beams.
Med Phys. 2011 Oct;38(10):5799.
NOTE: This article may be obtained online without charge:

Shay JW, Wright WE.
Role of telomeres and telomerase in cancer.
Semin Cancer Biol. 2011 Oct 15. [Epub ahead of print]

Juergens R, Becker W.
Human spatial orientation in non-stationary environments: Relation between self-turning perception and detection of surround motion.
Exp Brain Res. 2011 Oct 18. [Epub ahead of print]

Akin FW, Murnane OD, Pearson A, Byrd S, Kelly JK.
Normative data for the subjective visual vertical test during centrifugation.
J Am Acad Audiol. 2011 Jul;22(7):460-8.

McCaslin DL, Jacobson GP, Grantham SL, Piker EG, Verghese S.
The influence of unilateral saccular impairment on functional balance performance and self-report dizziness.
J Am Acad Audiol. 2011 Sep;22(8):542-9.

Santhi N, Thorne HC, van der Veen DR, Johnsen S, Mills SL, Hommes V, Schlangen LJ, Archer SN, Dijk DJ.
The spectral composition of evening light and individual differences in the suppression of melatonin and delay of sleep in humans.
J Pineal Res. 2011 Oct 24. [Epub ahead of print]

de Diego-Castilla G, Cruz-Gil P, Mateo-Marti E, Fernandez-Calvo P, Rivas LA,
Parro V.
Assessing antibody microarrays for space missions: Effect of long-term storage, gamma radiation, and temperature shifts on printed and fluorescently labeled antibodies.
Astrobiology. 2011 Oct;11(8):759-73.

Chen J, Liu R, Yang Y, Li J, Zhang X, Li J, Wang Z, Ma J.
The simulated microgravity enhances the differentiation of mesenchymal stem cells into neurons.
Neurosci Lett. 2011 Oct 12. [Epub ahead of print]

King JS, Veltman DM, Insall RH.
The induction of autophagy by mechanical stress.
Autophagy. 2011 Dec;7(12). [Epub ahead of print]

Peng X, Huang J, Xiong C, Fang J.
Cell adhesion nucleation regulated by substrate stiffness: A Monte Carlo study.
J Biomech. 2011 Oct 19. [Epub ahead of print]

Deguchi S, Matsui TS, Iio K.
The position and size of individual focal adhesions are determined by intracellular stress-dependent positive regulation.
Cytoskeleton (Hoboken). 2011 Oct 21. [Epub ahead of print]

Pompe T, Kaufmann M, Kasimir M, Johne S, Glorius S, Renner L, Bobeth M, Pompe W, Werner C.
Friction-controlled traction force in cell adhesion.
Biophys J. 2011 Oct 19;101(8):1863-70.

SpaceRef staff editor.