NASA Spaceline Current Awareness 31 August 2012 (Recent Space Life Science Research Results)

Next list: September 14, 2012

Papers deriving from NASA support:

A paper by Smith, Heer, et al. that appeared in the May 11 Current Awareness list as an epub (PubMed ID 22549960, PI=Smith) is now featured on the cover of the print copy of the journal: http://onlinelibrary.wiley.com/doi/10.1002/jbmr.1647/abstract The article is now available online without charge. Press release: http://www.nasa.gov/home/hqnews/2012/aug/HQ_12-291_ISS_Bone_Density.html

1 Paulus DC, Settlage DM.
Bilateral symmetry of ground reaction force with a motor-controlled resistance exercise system using a mechanical advantage barbell for spaceflight.
Biomed Sci Instrum. 2012;48:340-4.
http://www.ncbi.nlm.nih.gov/pubmed/22846303

2 Li Y, Wang M, Carra C, Cucinotta FA.
Modularized Smad-regulated TGF signaling pathway.
Math Biosci. 2012 Aug 6. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22892478
(PI: F.A. Cucinotta)

3 Ly P, Kim SB, Kaisani AA, Marian G, Wright WE, Shay JW.
Aneuploid human colonic epithelial cells are sensitive to AICAR-induced growth inhibition through EGFR degradation.
Oncogene. 2012 Aug 13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22890317
(PIs: J.W. Shay; A.J. Fornace/W.E. Wright/J.W. Shay/NSCOR; J.D. Minna/J.W. Shay/NSCOR)

4 Allen JD, Xie Y, Chen M, Girard L, Xiao G.
Comparing statistical methods for constructing large scale gene networks.
PLoS One. 2012;7(1):e29348. Epub 2012 Jan 17.
http://www.ncbi.nlm.nih.gov/pubmed/22272232
(PI: J.D. Minna/L. Girard/NSCOR)
NOTE: This article may be obtained online without charge.

5 Olsen RH, Agam M, Davis MJ, Raber J.
ApoE isoform-dependent deficits in extinction of contextual fear conditioning.
Genes Brain Behav. 2012 Aug 9. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22883220
(PI: J. Raber)

6 Shine JM, Naismith SL, Palavra NC, Lewis SJ, Moore ST, Dilda V, Morris TR.
Attentional set-shifting deficits correlate with the severity of freezing of gait in Parkinson’s disease.
Parkinsonism Relat Disord. 2012 Aug 20. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22906729
(PI: S.T. Moore)

7 Sun GS, Tou JC, Reiss-Bubenheim DA, Hill EL, Liittschwager KW, Girten BE, Pena-Yewkukhiw E.
Oxidative and nutrient stability of a standard rodent spaceflight diet during long-term storage.
Lab Anim (NY). 2012 Sep;41(9):252-9.
http://www.ncbi.nlm.nih.gov/pubmed/22914028
NOTE: This article is featured on the cover of the journal: http://www.labanimal.com/laban/journal/v41/n9/index.html

8 Rosenzweig JA, Chopra AK.
The effect of low shear force on the virulence potential of Yersinia pestis: New aspects that space-like growth conditions and the final frontier can teach us about a formidable pathogen.
Front Cell Infect Microbiol. 2012;2:107. Epub 2012 Aug 9.
http://www.ncbi.nlm.nih.gov/pubmed/22919696
NOTE: This article may be obtained online without charge via PubMed Central or at the publisher’s site: http://www.frontiersin.org/Cellular_and_Infection_Microbiology/10.3389/f…

9 Iscla I, Wray R, Blount P.
The dynamics of protein-protein interactions between domains of MscL at the cytoplasmic-lipid interface.
Channels (Austin). 2012 Jul/Aug;6(4).
http://www.ncbi.nlm.nih.gov/pubmed/22874845
(PI: P. Blount)
NOTE: This article is in a special issue on mechanosensitive ion channels: http://www.landesbioscience.com/journals/channels/toc/volume/6/issue/4/

10 McCoy KB, Derecho I, Wong T, Tran HM, Huynh TD, La Duc MT, Venkateswaran K, Mogul R.
Insights into the extremotolerance of Acinetobacter radioresistens 50v1, a Gram-negative bacterium isolated from the Mars Odyssey spacecraft.
Astrobiology. 2012 Aug 23. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22917036

11 Kaplan F, Zhao W, Richards JT, Wheeler RM, Guy CL, Levine LH.
Transcriptional and metabolic insights into the differential physiological responses of Arabidopsis to optimal and supraoptimal atmospheric CO(2).
PLoS One. 2012;7(8):e43583. Epub 2012 Aug 20.
http://www.ncbi.nlm.nih.gov/pubmed/22916280
NOTE: This article may be obtained online without charge.

Other papers of interest:

1 Crawford I, McBeth PB, Mitchelson M, Ferguson J, Tiruta C, Kirkpatrick AW.
How to set up a low cost tele-ultrasound capable videoconferencing system with wide applicability.
Crit Ultrasound J. 2012 May 29;4:13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22871099
NOTE: This article may be obtained online without charge: http://www.criticalultrasoundjournal.com/content/4/1/13/abstract

2 Jackson JR, Mula J, Kirby TJ, Fry CS, Lee JD, Ubele MF, Campbell KS, McCarthy JJ, Peterson CA, Dupont-Versteegden EE.
Satellite cell depletion does not inhibit adult skeletal muscle re-growth following unloading-induced atrophy.
Am J Physiol Cell Physiol. 2012 Aug 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22895262

3 Li Y, Li S, Niu ZY, Bao B, Shi X.
[The effect of Smads signal pathway on the osteogenesis of human periodontal ligament stem cells in simulated microgravity]
Shanghai Kou Qiang Yi Xue. 2012 Jun;21(3):246-50. Chinese.
http://www.ncbi.nlm.nih.gov/pubmed/22885480
NOTE: Translated title of journal is Shanghai Journal of Stomatology.

4 Guilhem G, Cornu C, Maffiuletti NA, Guevel A.
Neuromuscular adaptations to isoload versus isokinetic eccentric resistance training.
Med Sci Sports Exerc. 2012 Aug 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22903139

5 Cook SB, Murphy BG, LaBarbera KE.
Neuromuscular function following a bout of low-load blood flow restricted exercise.
Med Sci Sports Exerc. 2012 Aug 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22895371

6 Palumbo C, Rovesta C, Ferretti M.
Striated muscle fiber apoptosis after experimental tendon lesion in a rat model.
J Anat. 2012 Aug 13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22881388

7 Greenberg MJ, Lin T, Goldman YE, Shuman H, Ostap EM.
Myosin IC generates power over a range of loads via a new tension-sensing mechanism.
Proc Natl Acad Sci U S A. 2012 Aug 20. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22908250

8 Sherk VD, Chrisman C, Smith J, Young KC, Singh H, Bemben MG, Bemben DA.
Acute bone marker responses to whole-body vibration and resistance exercise in young women.
J Clin Densitom. 2012 Aug 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22902255

9 Chan ME, Adler BJ, Green DE, Rubin CT.
Bone structure and B-cell populations, crippled by obesity, are partially rescued by brief daily exposure to low-magnitude mechanical signals.
FASEB J. 2012 Aug 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22898923

10 Collette NM, Genetos DC, Economides AN, Xie L, Shahnazari M, Yao W, Lane NE, Harland RM, Loots GG.
Targeted deletion of Sost distal enhancer increases bone formation and bone mass.
Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14092-7. Epub 2012 Aug 10.
http://www.ncbi.nlm.nih.gov/pubmed/22886088
NOTE: This article may be obtained online without charge.

11 Robling AG.
The interaction of biological factors with mechanical signals in bone adaptation: Recent developments.
Curr Osteoporos Rep. 2012 Jun;10(2):126-31.
http://www.ncbi.nlm.nih.gov/pubmed/22538521
NOTE: This issue has a number of papers on topics related to signaling in bone: http://www.springerlink.com/content/1544-1873/10/2/

12 Brakspear KS, Mason DJ.
Glutamate signaling in bone.
Front Endocrinol (Lausanne). 2012;3:97. Epub 2012 Aug 6.
http://www.ncbi.nlm.nih.gov/pubmed/22888325
NOTE: This article may be obtained online without charge.

13 Zhou WJ, Liu ZH, Hao PJ, Xu S, Sun AJ, Li ZR.
[Expression of receptor activator of NF-B ligand and osteoprotegerin in peri-implant tissues during unloading period]
Zhonghua Kou Qiang Yi Xue Za Zhi. 2012 May;47(5):310-3. Chinese.
http://www.ncbi.nlm.nih.gov/pubmed/22883830
NOTE: Translated title of journal is Chinese Journal of Stomatology.

14 Manova VI, Singh SK, Iliakis G.
Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin.
Genome Integr. 2012 Aug 22;3:4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22908892
NOTE: This article may be obtained online without charge.

15 Wedenberg M, Lind BK, Hardemark B.
A model for the relative biological effectiveness of protons: The tissue specific parameter / of photons is a predictor for the sensitivity to LET changes.
Acta Oncol. 2012 Aug 22. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22909391

16 Endo A, Sato T.
Analysis of linear energy transfers and quality factors of charged particles produced by spontaneous fission neutrons from 252Cf and 244Pu in the human body.
Radiat Prot Dosimetry. 2012 Aug 19. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22908356

17 Antonovic L, Brahme A, Furusawa Y, Toma-Dasu I.
Radiobiological description of the LET dependence of the cell survival of oxic and anoxic cells irradiated by carbon ions.
J Radiat Res. 2012 Aug 21. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22915783
NOTE: This article may be obtained online without charge.

18 Yonai S, Matsufuji N, Namba M.
Calculation of out-of-field dose distribution in carbon-ion radiotherapy by Monte Carlo simulation.
Med Phys. 2012 Aug;39(8):5028-39.
http://www.ncbi.nlm.nih.gov/pubmed/22894428

19 Raisali G, Mirzakhanian L, Masoudi SF, Semsarha F.
Calculation of DNA strand breaks due to direct and indirect effects of Auger electrons from incorporated (123)I and (125)I radionuclides using Geant4 computer code.
Int J Radiat Biol. 2012 Aug 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22892102

20 Derveni M, Hands A, Allen M, Sims MR, Cullen DC.
Effects of simulated space radiation on immunoassay components for life-detection experiments in planetary exploration missions.
Astrobiology. 2012 Aug 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22897155

21 Kindt KS, Finch G, Nicolson T.
Kinocilia mediate mechanosensitivity in developing zebrafish hair cells.
Dev Cell. 2012 Aug 14;23(2):329-41.
http://www.ncbi.nlm.nih.gov/pubmed/22898777

22 Massot C, Schneider AD, Chacron MJ, Cullen KE.
The vestibular system implements a linear-nonlinear transformation in order to encode self-motion.
PLoS Biol. 2012 Jul;10(7):e1001365. Epub 2012 Jul 24.
http://www.ncbi.nlm.nih.gov/pubmed/22911113
NOTE: This article may be obtained online without charge.

23 Barresi M, Grasso C, Bruschini L, Berrettini S, Manzoni D.
Effects of trunk-to-head rotation on the labyrinthine responses of rat reticular neurons.
Neuroscience. 2012 Aug 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22903024

24 Plaisier MA, Smeets JB.
Mass is all that matters in the size-weight illusion.
PLoS One. 2012;7(8):e42518. Epub 2012 Aug 9.
http://www.ncbi.nlm.nih.gov/pubmed/22912704
NOTE: This article may be obtained online without charge.

25 Cooke NJ, Duchon A, Gorman JC, Keyton J, Miller A.
Preface to the special section on methods for the analysis of communication.
Hum Factors. 2012 Aug;54(4):485-8.
http://www.ncbi.nlm.nih.gov/pubmed/22908673
NOTE: This preface introduces a special section consisting of seven articles on this topic, including communication in teams: http://hfs.sagepub.com/content/54/4.toc

26 Jackson ML, Gunzelmann G, Whitney P, Hinson JM, Belenky G, Rabat A, Van Dongen HP.
Deconstructing and reconstructing cognitive performance in sleep deprivation.
Sleep Med Rev. 2012 Aug 9. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22884948

27 Pacello F, Rotilio G, Battistoni A.
Low-shear modeled microgravity enhances Salmonella enterica resistance to hydrogen peroxide through a mechanism involving KatG and KatN.
Open Microbiol J. 2012;6:53-64. Epub 2012 Jul 27.
http://www.ncbi.nlm.nih.gov/pubmed/22888375
NOTE: This article may be obtained online without charge via PubMed Central or at the publisher’s site: http://dx.doi.org/10.2174/1874285801206010053

28 Korin N, Kanapathipillai M, Matthews BD, Crescente M, Brill A, Mammoto T, Ghosh K, Jurek S, Bencherif SA, Bhatta D, Coskun AU, Feldman CL, Wagner DD, Ingber DE.
Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels.
Science. 2012 Aug 10;337(6095):738-42. Epub 2012 Jul 5.
http://www.ncbi.nlm.nih.gov/pubmed/22767894

29 Malcolm HR, Maurer JA.
The mechanosensitive channel of small conductance (MscS) superfamily: Not just mechanosensitive channels anymore.
Chembiochem. 2012 Aug 22. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22915507

30 Huang C, Akaishi S, Ogawa R.
Mechanosignaling pathways in cutaneous scarring.
Arch Dermatol Res. 2012 Aug 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22886298

31 Piragyte I, Jun CD.
Actin engine in immunological synapse.
Immune Netw. 2012 Jun;12(3):71-83. Epub 2012 Jun 30.
http://www.ncbi.nlm.nih.gov/pubmed/22916042
NOTE: This article may be obtained online without charge via PubMed Central or at the publisher’s site: http://dx.doi.org/10.4110/in.2012.12.3.71

32 Burke DP, Kelly DJ.
Substrate stiffness and oxygen as regulators of stem cell differentiation during skeletal tissue regeneration: A mechanobiological model.
PLoS One. 2012;7(7):e40737. Epub 2012 Jul 24.
http://www.ncbi.nlm.nih.gov/pubmed/22911707
NOTE: This article may be obtained online without charge.

33 ivanovi BD.
Surface tip-to-base Ca(2+) and H (+) ionic fluxes are involved in apical growth and graviperception of the Phycomyces stage I sporangiophore.
Planta. 2012 Aug 22. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22910875