NASA Spaceline Current Awareness 27 January 2012 (Recent Space Life Science Research Results)

Papers deriving from NASA support:

1
De Ridder S, Migeotte PF, Neyt X, Pattyn N, Prisk GK.
Three-dimensional ballistocardiography in microgravity: A review of past research.
Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:4267-70.
http://www.ncbi.nlm.nih.gov/pubmed/22255282
(PI: G.K. Prisk)
NOTE: This article includes brief reviews of earlier ballistocardiography research during parabolic flight and space flight, including Salyut 6, Spacelab D-1 (STS-61A), and Spacelab D-2 (STS-55).

2
Migeotte PF, Tank J, Pattyn N, Funtova I, Baevsky R, Neyt X, Prisk GK.
Three dimensional ballistocardiography: Methodology and results from microgravity and dry immersion.
Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:4271-4.
http://www.ncbi.nlm.nih.gov/pubmed/22255283
(PI: G.K. Prisk)
NOTE: This article includes an analysis of data from Spacelab D-2 (STS-55), using a new method of analysis.

3
Henderson AC, Sa RC, Barash IA, Holverda S, Buxton RB, Hopkins SR, Prisk GK.
Rapid intravenous infusion of 20 mL/kg saline alters the distribution of perfusion in healthy supine humans.
Respir Physiol Neurobiol. 2011 Dec 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22227320
(PIs: R.C. Sa, NSBRI Postdoctoral Fellowship Program; G.K. Prisk)

4
Spiljak Pakkanen M, Domanjko Petri A, Olsen LH, Stepani A, Schlegel TT, Falk T, Rasmussen CE, Starc V.
Advanced electrocardiographic parameters change with severity of mitral regurgitation in Cavalier King Charles spaniels in sinus rhythm.
J Vet Intern Med. 2012 Jan-Feb;26(1):93-100. Epub 2011 Dec 14.
http://www.ncbi.nlm.nih.gov/pubmed/22168834

5
Pandorf CE, Jiang W, Qin AX, Bodell PW, Baldwin KM, Haddad F.
Regulation of an antisense RNA with the transition of neonatal to IIb myosin heavy chain during postnatal development and hypothyroidism in rat skeletal muscle.
Am J Physiol Regul Integr Comp Physiol. 2012 Jan 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22262309
(PI: C.E. Pandorf, NSBRI Postdoctoral Fellowship Program)

6
Zheng Z, Ng WL, Zhang X, Olson JJ, Hao C, Curran WJ, Wang Y.
RNAi-mediated targeting of non-coding and coding sequences in DNA repair gene messages efficiently radiosensitizes human tumor cells.
Cancer Res. 2012 Jan 11. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22237628
(PI: Y. Wang/NSCOR)

7
Krigsfeld GS, Sanzari JK, Kennedy AR.
The effects of proton radiation on the prothrombin and partial thromboplastin times of irradiated ferrets.
Int J Radiat Biol. 2012 Jan 6. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22221163
(PI: A.R. Kennedy/Center of Acute Radiation Research)

8
Van Dongen HP, Bender AM, Dinges DF.
Systematic individual differences in sleep homeostatic and circadian rhythm contributions to neurobehavioral impairment during sleep deprivation.
Accid Anal Prev. 2012 Mar;45 Suppl:11-6. Epub 2011 Nov 23.
http://www.ncbi.nlm.nih.gov/pubmed/22239924
(PI: D.F. Dinges)
NOTE: This article may be obtained online without charge.

9
Citi L, Bianchi MT, Klerman EB, Barbieri R.
Instantaneous monitoring of sleep fragmentation by point process heart rate variability and respiratory dynamics.
Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:7735-8.
http://www.ncbi.nlm.nih.gov/pubmed/22256131
(PI: E.B. Klerman)

10
Catauro PM, Perchonok MH.
Assessment of the long-term stability of retort pouch foods to support extended duration spaceflight.
J Food Sci. 2012 Jan;77(1):S29-39. Epub 2011 Nov 10.
http://www.ncbi.nlm.nih.gov/pubmed/22260129
(PIs: P.M. Catauro, M.H. Perchonok)

11
Yang LM, Wray R, Parker J, Wilson D, Duran RS, Blount P.
Three routes to modulate the pore size of the MscL channel/nanovalve.
ACS Nano. 2012 Jan 6. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22206349
(PI: P. Blount)

12
Paul AL, Zupanska AK, Ostrow DT, Zhang Y, Sun Y, Li JL, Shanker S, Farmerie WG, Amalfitano CE, Ferl RJ.
Spaceflight transcriptomes: Unique responses to a novel environment.
Astrobiology. 2012 Jan;12(1):40-56. Epub 2012 Jan 5.
http://www.ncbi.nlm.nih.gov/pubmed/22221117
(PIs: R.J. Ferl, A.L. Paul)
NOTE: STS-131 results.

Other papers of interest:

1
Battista N, Meloni MA, Bari M, Mastrangelo N, Galleri G, Rapino C, Dainese E, Agro AF, Pippia P, Maccarrone M.
5-Lipoxygenase-dependent apoptosis of human lymphocytes in the International Space Station: Data from the ROALD experiment.
FASEB J. 2012 Jan 17. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22253478
NOTE: ISS results.

2
Aletti F, Ferrario M, Xu D, Greaves DK, Shoemaker KJ, Arbeille P, Cerutti S, Hughson RL, Baselli G.
System identification of baroreflex response to mild lower body negative pressure.
Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:2550-3.
http://www.ncbi.nlm.nih.gov/pubmed/22254861
NOTE: Analysis uses pre-bed rest control data from WISE-2005 bed rest study.

3
Karata Z, Alp H, ap F, Altin H, Baysal T, Karaarslan S.
Usability of QTc dispersion for the prediction of orthostatic intolerance syndromes.
Eur J Paediatr Neurol. 2012 Jan 8. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22226850

4
Olufsen MS, Smith B, Mehlsen J, Ottesen J.
The impact of gravity during head-up tilt.
Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:2399-402.
http://www.ncbi.nlm.nih.gov/pubmed/22254825

5
Lin CT, Lin CL, Chiu TW, Duann JR, Jung TP.
Effect of respiratory modulation on relationship between heart rate variability and motion sickness.
Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:1921-4.
http://www.ncbi.nlm.nih.gov/pubmed/22254707

6
Kim J, Napadow V, Kuo B, Barbieri R.
A combined HRV-fMRI approach to assess cortical control of cardiovagal modulation by motion sickness.
Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:2825-8.
http://www.ncbi.nlm.nih.gov/pubmed/22254929

7
Guo BS, Cheung KK, Yeung SS, Zhang BT, Yeung EW.
Electrical stimulation influences satellite cell proliferation and apoptosis in unloading-induced muscle atrophy in mice.
PLoS One. 2012;7(1):e30348. Epub 2012 Jan 12.
http://www.ncbi.nlm.nih.gov/pubmed/22253929
NOTE: This article may be obtained online without charge.

8
Liu HJ, Teng XZ, Huang KL Chen XP.
[Current understandings about the signaling mechanisms involved in disuse muscle atrophy]
Sheng Li Ke Xue Jin Zhan. 2011 Oct;42(5):386-9. Chinese.
http://www.ncbi.nlm.nih.gov/pubmed/22242410

9
Fonseca H, Powers SK, Goncalves D, Santos A, Mota MP, Duarte JA.
Physical inactivity is a major contributor to ovariectomy-induced sarcopenia.
Int J Sports Med. 2012 Jan 19. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22261826

10
Beck TW, Kasishke PR 2nd, Stock MS, DeFreitas JM.
Neural contributions to concentric versus eccentric exercise-induced strength loss.
J Strength Cond Res. 2011 Dec 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22207262

11
Karsenty G, Ferron M.
The contribution of bone to whole-organism physiology.
Nature. 2012 Jan 19;481(7381):314-20.
http://www.ncbi.nlm.nih.gov/pubmed/22258610

12
Bouvard B, Mabilleau G, Legrand E, Audran M, Chappard D.
Micro and macroarchitectural changes at the tibia after botulinum toxin injection in the growing rat.
Bone. 2012 Jan 10. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22252044

13
Sheng ZF, Ma YL, Tong D, Fang DY, Liang QC, Liu LH, Zhang J, Liao EY.
Strontium ranelate prevents bone loss in a rat model of localized muscle paralysis.
Ann Biomed Eng. 2012 Jan 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22237860

14
Srinivasan S, Gross TS, Bain SD.
Bone mechanotransduction may require augmentation in order to strengthen the senescent skeleton.
Ageing Res Rev. 2012 Jan 5. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22240208

15
Sun X, McLamore E, Kishore V, Fites K, Slipchenko M, Porterfield DM, Akkus O.
Mechanical stretch induced calcium efflux from bone matrix stimulates osteoblasts.
Bone. 2011 Dec 29;50(3):581-91. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22227434

16
Wysocki A, Butler M, Shamliyan T, Kane RL.
Whole-body vibration therapy for osteoporosis [Internet].
Rockville (MD): Agency for Healthcare Research and Quality (US); 2011 Nov.
http://www.ncbi.nlm.nih.gov/pubmed/22238804
NOTE: This volume may be obtained online without charge.

17
Doherty AH, Frampton JD, Vinyard CJ.
Hibernation does not reduce cortical bone density, area or second moments of inertia in woodchucks (Marmota monax).
J Morphol. 2012 Jan 11. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22234945

18
Xu H, Gao L, Che T, Du W, Li Q, Gao Q, Wang Z.
The effects of (12)C(6+) irradiation on cell cycle, apoptosis, and expression of caspase-3 in the human lung cancer cell line H1299.
Cancer Biother Radiopharm. 2012 Jan 13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22242595

19
Niemantsverdriet M, van Goethem MJ, Bron R, Hogewerf W, Brandenburg S, Langendijk JA, van Luijk P, Coppes RP.
High and low LET radiation differentially induce normal tissue damage signals.
Int J Radiat Oncol Biol Phys. 2012 Jan 13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22245200

20
Boldt S, Knops K, Kriehuber R, Wolkenhauer O.
A frequency based gene selection method to identify robust biomarkers for radiation dose prediction.
Int J Radiat Biol. 2012 Jan 10. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22233095

21
Dalecki M, Draeger T, Mierau A, Bock O.
Production of finely graded forces in humans: Effects of simulated weightlessness by water immersion.
Exp Brain Res. 2012 Jan 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22237940

22
Kashima T, Wada Y, Inui T, Hirata Y.
Effect of gravity on learning and memory of prism adaptation.
Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:3568-72.
http://www.ncbi.nlm.nih.gov/pubmed/22255110

23
Cullen KE.
The vestibular system: Multimodal integration and encoding of self-motion for motor control.
Trends Neurosci. 2012 Jan 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22245372

24
Shanidze N, Lim K, Dye J, King WM.
Galvanic stimulation of the vestibular periphery in guinea pigs during passive whole-body rotation and self-generated head movement.
J Neurophysiol. 2012 Jan 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22262827

25
Bae GY, Flombaum JI.
Close encounters of the distracting kind: Identifying the cause of visual tracking errors.
Atten Percept Psychophys. 2012 Jan 4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22215380

26
Bourke AK, O’Donovan K, Clifford A, Olaighin G, Nelson J.
Optimum gravity vector and vertical acceleration estimation using a tri-axial accelerometer for falls and normal activities.
Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:7896-9.
http://www.ncbi.nlm.nih.gov/pubmed/22256171

27
Vukanti R, Model MA, Leff LG.
Effect of modeled reduced gravity conditions on bacterial morphology and physiology.
BMC Microbiol. 2012 Jan 12;12:4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22239851
NOTE: This article may be obtained online without charge.

28
Li P, Zhang Y, Wang YM, Duan CM, Hao T, Wu BL, Wang CY.
RCCS enhances EOE cell proliferation and their differentiation into ameloblasts.
Mol Biol Rep. 2012 Jan;39(1):309-17. Epub 2011 Jun 11.
http://www.ncbi.nlm.nih.gov/pubmed/21667111

29
Muhammad H, Rais Y, Miosge N, Ornan EM.
The primary cilium as a dual sensor of mechanochemical signals in chondrocytes.
Cell Mol Life Sci. 2012 Jan 13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22241332
NOTE: This article may be obtained online without charge.

30
Wann AK, Zuo N, Haycraft CJ, Jensen CG, Poole CA, McGlashan SR, Knight MM.
Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes.
FASEB J. 2012 Jan 13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22223751

31
Lin YC, Kramer CM, Chen CS, Reich DH.
Probing cellular traction forces with magnetic nanowires and microfabricated force sensor arrays.
Nanotechnology. 2012 Feb 24;23(7):075101. Epub 2012 Jan 20.
http://www.ncbi.nlm.nih.gov/pubmed/22260885

32
Brunoud G, Wells DM, Oliva M, Larrieu A, Mirabet V, Burrow AH, Beeckman T, Kepinski S, Traas J, Bennett MJ, Vernoux T.
A novel sensor to map auxin response and distribution at high spatio-temporal resolution.
Nature. 2012 Jan 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22246322