NASA Spaceline Current Awareness 25 May 2012 (Recent Space Life Science Research Results)

Next list: June 8, 2012

Papers deriving from NASA support:

1
Davis SA, Davis BL.
Exercise equipment used in microgravity: Challenges and opportunities.
Curr Sports Med Rep. 2012 May-Jun;11(3):142-7.
http://www.ncbi.nlm.nih.gov/pubmed/22580492
(PI: B.L. Davis)

2
Jayroe J, Soulsby M, Chowdhury P.
Attenuation of tissue oxidative stress by dietary restriction in rats on simulated microgravity.
Ann Clin Lab Sci. 2012 Spring;42(2):140-4.
http://www.ncbi.nlm.nih.gov/pubmed/22585609

3
Gupta S, Vijayaraghavan S, Uzer G, Judex S.
Multiple exposures to unloading decrease bone’s responsivity but compound skeletal losses in C57BL/6 mice.
Am J Physiol Regul Integr Comp Physiol. 2012 May 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22592559
(PI: S. Judex)

4
Lin L, Cheng J, Lin W, Qin YX.
Prediction of trabecular bone principal structural orientation using quantitative ultrasound scanning.
J Biomech. 2012 May 7. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22560370
(PI: Y.X. Qin)

5
Alwood JS, Kumar A, Tran LH, Wang A, Limoli CL, Globus RK.
Low-dose, ionizing radiation and age-related changes in skeletal microarchitecture.
J Aging Res. 2012;2012:481983. Epub 2012 Apr 18.
http://www.ncbi.nlm.nih.gov/pubmed/22570786
(PIs: R.K. Globus, C.L. Limoli)
NOTE: This article may be obtained online without charge.

6
Suman S, Datta K, Trani D, Laiakis EC, Strawn SJ, Fornace AJ Jr.
Relative biological effectiveness of (12)C and (28)Si radiation in C57BL/6J mice.
Radiat Environ Biophys. 2012 May 5. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22562428
(PIs: A.J. Fornace; A.J. Fornace/K. Datta/NSCOR; D. Trani, NSBRI Postdoctoral Fellowship Program)

7
Thomas SN, Waters KM, Morgan WF, Yang AJ, Baulch JE.
Quantitative proteomic analysis of mitochondrial proteins reveals prosurvival mechanisms in the perpetuation of radiation-induced genomic instability.
Free Radic Biol Med. 2012 Apr 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22569412
(PI: J.E. Baulch)

8
Sharungbam GD, Schwager C, Chiblak S, Brons S, Hlatky L, Haberer T, Debus J, Abdollahi A.
Identification of stable endogenous control genes for transcriptional profiling of photon, proton and carbon-ion irradiated cells.
Radiat Oncol. 2012 May 17;7:70. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22594372
(PI: L. Hlatky/A. Abdollahi/NSCOR)
NOTE: This article may be obtained online without charge.

9
Brady RA, Peters BT, Batson CD, Ploutz-Snyder R, Mulavara AP, Bloomberg JJ.
Gait adaptability training is affected by visual dependency.
Exp Brain Res. 2012 May 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22585123
(PI: J.J. Bloomberg)

Other papers of interest:

1
Kelsen J, Bartels LE, Dige A, Hvas CL, Frings-Meuthen P, Boehme G, Thomsen MK, Fenger-Gron M, Dahlerup JF.
21 Days head-down bed rest induces weakening of cell-mediated immunity – Some spaceflight findings confirmed in a ground-based analog.
Cytokine. 2012 May 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22595648
NOTE: Bed rest study.

2
Kiviniemi AM, Frances MF, Rachinsky M, Craen R, Petrella RJ, Huikuri HV, Tulppo MP, Shoemaker JK.
Non-alpha-adrenergic effects on systemic vascular conductance during lower-body negative pressure, static exercise and muscle metaboreflex activation.
Acta Physiol (Oxf). 2012 May 17. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22591110

3
Logan IC, Witham MD.
Efficacy of treatments for orthostatic hypotension: A systematic review.
Age Ageing. 2012 May 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22591985

4
Puca A, Russo G, Giordano A.
Properties of mechano-transduction via simulated microgravity and its effects on intracellular trafficking of VEGFR’s.
Oncotarget. 2012 Apr;3(4):426-34.
http://www.ncbi.nlm.nih.gov/pubmed/22566481
NOTE: This article may be obtained online without charge.

5
Thompson WR, Rubin CT, Rubin J.
Mechanical regulation of signaling pathways in bone.
Gene. 2012 May 2. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22575727

6
Mateus J, Hargens AR.
Photoplethysmography for non-invasive in vivo measurement of bone hemodynamics.
Physiol Meas. 2012 May 4;33(6):1027-42. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22562998

7
Manske SL, Good CA, Zernicke RF, Boyd SK.
High-frequency, low-magnitude vibration does not prevent bone loss resulting from muscle disuse in mice following botulinum toxin injection.
PLoS One. 2012;7(5):e36486. Epub 2012 May 10.
http://www.ncbi.nlm.nih.gov/pubmed/22590551
NOTE: This article may be obtained online without charge.

8
Wade-Gueye NM, Boudiffa M, Vanden-Bossche A, Laroche N, Aubin JE, Vico L, Lafage-Proust MH, Malaval L.
Absence of bone sialoprotein (BSP) impairs primary bone formation and resorption: The marrow ablation model under PTH challenge.
Bone. 2012 May;50(5):1064-73.
http://www.ncbi.nlm.nih.gov/pubmed/22586700

9
Wein MN, Jones DC, Shim JH, Aliprantis AO, Sulyanto R, Lazarevic V, Poliachik SL, Gross TS, Glimcher LH.
Control of bone resorption in mice by Schnurri-3.
Proc Natl Acad Sci U S A. 2012 May 22;109(21):8173-8. Epub 2012 May 9.
http://www.ncbi.nlm.nih.gov/pubmed/22573816

10
Rangaswami H, Schwappacher R, Tran T, Chan GC, Zhuang S, Boss GR, Pilz RB.
Protein kinase G and focal adhesion kinase converge on a Src/Akt/-catenin signaling module in osteoblast mechanotransduction.
J Biol Chem. 2012 May 4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22563076
NOTE: This article may temporarily be obtained online without charge.

11
Maimoun L, Brennan-Speranza TC, Rizzoli R, Ammann P.
Effects of ovariectomy on the changes in microarchitecture and material level properties in response to hind leg disuse in female rats.
Bone. 2012 May 9. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22580391

12
Wuenschel M, Leichtle U, Lo J, Wuelker N, Mueller O.
Differences in tibiofemoral kinematics between the unloaded robotic passive path and a weightbearing knee simulator.
Orthop Rev (Pavia). 2012 Jan 2;4(1):e2. Epub 2012 Jan 3.
http://www.ncbi.nlm.nih.gov/pubmed/22577503
NOTE: This article may be obtained online without charge via PubMed Central or at the publisher’s site: http://www.pagepress.org/journals/index.php/or/article/view/or.2012.e2

13
Bruusgaard JC, Egner IM, Larsen TK, Dupre-Aucouturier S, Desplanches D, Gundersen K.
No change in myonuclear number during muscle unloading and reloading.
J Appl Physiol. 2012 May 10. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22582213

14
Leiter JR, Upadhaya R, Anderson JE.
Nitric oxide and voluntary exercise together promote quadriceps hypertrophy and increase vascular density in female 18-mo-old mice.
Am J Physiol Cell Physiol. 2012 May;302(9):C1306-15. Epub 2012 Feb 8.
http://www.ncbi.nlm.nih.gov/pubmed/22322971

15
Klammer H, Zhang LH, Kadhim M, Iliakis G.
Dependence of adaptive response and its bystander transmission on the genetic background of tested cells.
Int J Radiat Biol. 2012 May 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22574641

16
Faria FP, Dickman R, Moreira CH.
Models of the radiation-induced bystander effect.
Int J Radiat Biol. 2012 May 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22587665

17
Kujjo LL, Ronningen R, Ross P, Pereira RJ, Rodriguez R, Beyhan Z, Goissis MD, Baumann T, Kagawa W, Camsari C, Smith GW, Kurumizaka H, Yokoyama S, Cibelli JB, Perez GI.
RAD51 plays a crucial role in halting cell death program induced by ionizing radiation in bovine oocytes.
Biol Reprod. 2012 Mar 1;86(3):76.
http://www.ncbi.nlm.nih.gov/pubmed/22190703
NOTE: This article may be obtained online without charge.

18
Hirano T, Kazama Y, Ohbu S, Shirakawa Y, Liu Y, Kambara T, Fukunishi N, Abe T.
Molecular nature of mutations induced by high-LET irradiation with argon and carbon ions in Arabidopsis thaliana.
Mutat Res. 2012 May 8. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22579628

19
Gabriel M, Frippiat JP, Frey H, Horn ER.
The sensitivity of an immature vestibular system to altered gravity.
J Exp Zool A Ecol Genet Physiol. 2012 May 8. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22570271
NOTE: Results of Soyuz TMA8 mission to ISS (Soyuz TMA7 return).

20
DeAngelis GC, Angelaki DE.
Visual-vestibular integration for self-motion perception.
In: Murray MM, Wallace MT, editors. The Neural Bases of Multisensory Processes. Boca Raton (FL): CRC Press; 2012. Chapter 31.
http://www.ncbi.nlm.nih.gov/pubmed/22593867
NOTE: This article may be obtained online without charge.

21
Roll R, Kavounoudias A, Albert F, Legre R, Gay A, Fabre B, Roll JP.
Illusory movements prevent cortical disruption caused by immobilization.
Neuroimage. 2012 May 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22584228

22
Tarnutzer AA, Palla A, Marti S, Schuknecht B, Straumann D.
Hypertrophy of the inferior olivary nucleus impacts perception of gravity.
Front Neurol. 2012;3:79. Epub 2012 May 11.
http://www.ncbi.nlm.nih.gov/pubmed/22593754
NOTE: This article may be obtained online without charge.

23
Crane BT.
Fore-aft translation aftereffects.
Exp Brain Res. 2012 May 5. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22562589

24
Sierra-Hidalgo F, de Pablo-Fernandez E, Herrero-San Martin A, Correas-Callero E, Herreros-Rodriguez J, Romero-Munoz JP, Martin-Gil L.
Clinical and imaging features of the room tilt illusion.
J Neurol. 2012 May 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22588254

25
Boselli F, Obrist D, Kleiser L.
Vortical flow in the utricle and the ampulla: A computational study on the fluid dynamics of the vestibular system.
Biomech Model Mechanobiol. 2012 May 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22588372

26
Roditi RE, Crane BT.
Suprathreshold asymmetries in human motion perception.
Exp Brain Res. 2012 Jun;219(3):369-79. Epub 2012 May 5.
http://www.ncbi.nlm.nih.gov/pubmed/22562587

27
Frenzel H, Bohlender J, Pinsker K, Wohlleben B, Tank J, Lechner SG, Schiska D, Jaijo T, Rueschendorf F, Saar K, Jordan J, Millan JM, Gross M, Lewin GR.
A genetic basis for mechanosensory traits in humans.
PLoS Biol. 2012 May;10(5):e1001318. Epub 2012 May 1.
http://www.ncbi.nlm.nih.gov/pubmed/22563300
NOTE: This article may be obtained online without charge.

28
Tahara Y, Kuroda H, Saito K, Nakajima Y, Kubo Y, Ohnishi N, Seo Y, Otsuka M, Fuse Y, Ohura Y, Komatsu T, Moriya Y, Okada S, Furutani N, Hirao A, Horikawa K, Kudo T, Shibata S.
In vivo monitoring of peripheral circadian clocks in the mouse.
Curr Biol. 2012 May 10. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22578421

29
Choong YK, Chen X, Jamal JA, Wang Q, Lan J.
Preliminary results of determination of chemical changes on Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (W.Curt.:Fr.)P. Karst. (higher basidiomycetes) carried by Shenzhou I Spaceship with FTIR and 2D-IR correlation spectroscopy.
Int J Med Mushrooms. 2012;14(3):295-305.
http://www.ncbi.nlm.nih.gov/pubmed/22577979
NOTE: Shenzhou 1 results.

30
Takebe T, Kobayashi S, Kan H, Suzuki H, Yabuki Y, Mizuno M, Adegawa T, Yoshioka T, Tanaka J, Maegawa J, Taniguchi H.
Human elastic cartilage engineering from cartilage progenitor cells using rotating wall vessel bioreactor.
Transplant Proc. 2012 May;44(4):1158-61.
http://www.ncbi.nlm.nih.gov/pubmed/22564652

31
Aoyagi H, Kuroda A.
Effects of low-shear modeled microgravity on a microbial community filtered through a 0.2-m filter and its potential application in screening for novel microorganisms.
J Biosci Bioeng. 2012 May 7. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22571963

32
Goldmann WH.
Mechanotransduction in cells.
Cell Biol Int. 2012 Jun 1;36(6):567-70.
http://www.ncbi.nlm.nih.gov/pubmed/22568704

33
Pan F, Liu S, Wang Z, Shang P, Xiao W.
Digital holographic microscopy long-term and real-time monitoring of cell division and changes under simulated zero gravity.
Opt Express. 2012 May 7;20(10):11496-505.
http://www.ncbi.nlm.nih.gov/pubmed/22565769
NOTE: This article may be obtained online without charge: http://www.opticsinfobase.org/oe/abstract.cfm?uri=oe-20-10-11496

34
Kim ST, Shin Y, Brazin K, Mallis RJ, Sun ZY, Wagner G, Lang MJ, Reinherz EL.
TCR mechanobiology: Torques and tunable structures linked to early T cell signaling.
Front Immunol. 2012;3:76. Epub 2012 Apr 18.
http://www.ncbi.nlm.nih.gov/pubmed/22566957
NOTE: This article may be obtained online without charge.

35
Fisahn J, Yazdanbakhsh N, Klingele E, Barlow P.
Arabidopsis thaliana root growth kinetics and lunisolar tidal acceleration.
New Phytol. 2012 May 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22583121