NASA Spaceline Current Awareness 25 March 2011 (Recent Space Life Science Research Results)

Papers deriving from NASA support:

1
Hamilton DR, Alferova IV, Sargsyan AE, Fincke EM, Magnus SH, Lonchakov YV, Dulchavsky SA, Ebert D, Garcia K, Martin D, Matveev VP, Voronkov YI, Melton SL, Bogomolov VV, Duncan JM.
Right ventricular tissue Doppler assessment in space during circulating volume modification using the Braslet device.
Acta Astronaut. 2011 May-Jun;68(9-10):1501-8.
http://dx.doi.org/10.1016/j.actaastro.2009.11.015
(PIs: J.M. Duncan, S.A. Dulchavsky)
NOTE: ISS results.

2
Dulchavsky SA, Sargsyan AE, Garcia KM, Melton SL, Ebert D, Hamilton DR.
Intuitive ultrasonography for autonomous medical care in limited-resource environments.
Acta Astronaut. 2011 May-Jun;68(9-10):1595-607.
http://dx.doi.org/10.1016/j.actaastro.2009.08.024
(PI: S.A. Dulchavsky)

3
Das B, Bennett PV, Cutter NC, Sutherland JC, Sutherland BM.
Melatonin protects human cells from clustered DNA damages, killing and acquisition of soft agar growth induced by X-rays or 970 MeV/n Fe ions.
Int J Radiat Biol. 2011 Mar 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21401316
(PIs: B.M. Sutherland, A. Gewirtz)

4
Young LR.
Optimal estimator models for spatial orientation and vestibular nystagmus.
Exp Brain Res. 2011 Mar 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21416377
(PI: L.R. Young)

5
Tomilovskaya ES, Reschke MF, Krnavek JM, Kozlovskaya I.
Effects of long-duration space flight on target acquisition.
Acta Astronaut. 2011 May-Jun;68(9-10):1454-61.
http://dx.doi.org/10.1016/j.actaastro.2009.11.005
NOTE: Mir results.

6
Roma PG, Hursh SR, Hienz RD, Emurian HH, Gasior ED, Brinson ZS, Brady JV.
Behavioral and biological effects of autonomous versus scheduled mission management in simulated space-dwelling groups.
Acta Astronaut. 2011 May-Jun;68(9-10):1581-8.
http://dx.doi.org/10.1016/j.actaastro.2009.09.034
(PI: J.V. Brady)

7
Jennings ME, Quick LN, Soni A, Davis RR, Crosby K, Ott CM, Nickerson CA, Wilson JW.
Characterization of the Salmonella enterica serovar Typhimurium ydcI gene which encodes a conserved DNA binding protein required for full acid stress resistance.
J Bacteriol. 2011 Mar 11. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21398541
(PI: C.A. Nickerson)

8
Ritter JA, Bhadra SJ, Ebner AD.
On the use of the dual-process Langmuir model for correlating unary equilibria and predicting mixed-gas adsorption equilibria.
Langmuir. 2011 Mar 17. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21413784
(PI: J.A. Ritter)

9
MacLeish MY, Thomson WA, Moreno NP.
The National Space Biomedical Research Institute’s Education and Public Outreach Program: Working toward a global 21st century space exploration society.
Acta Astronaut. 2011 May-Jun;68(9-10):1614-9.
http://dx.doi.org/10.1016/j.actaastro.2009.12.005

Other papers of interest:

1
Kozlovskaya IB, Tomilovskaya ES, Gerzer R.
The 17th IAA Humans in Space Symposium 2009 in Moscow, Russia.
Acta Astronaut. 2011 May-Jun;68(9-10):1417.
http://dx.doi.org/10.1016/j.actaastro.2011.01.009
NOTE: This editorial introduces this issue of Acta Astronautica, which contains papers deriving from the 17th IAA Humans in Space Symposium. All 28 papers in the issue are included in this list; five of the papers are in the first part of the list.

2
Grigoriev AI, Kotovskaya AR, Fomina GA.
The human cardiovascular system during space flight.
Acta Astronaut. 2011 May-Jun;68(9-10):1495-500.
http://dx.doi.org/10.1016/j.actaastro.2009.11.013
NOTE: Review of Salyut-7 and Mir results.

3
Goswami N, Lackner HK, Papousek I, Jezova D, Montani JP, Hinghofer-Szalkay HG.
Interaction of mental and orthostatic stressors.
Acta Astronaut. 2011 May-Jun;68(9-10):1509-16.
http://dx.doi.org/10.1016/j.actaastro.2009.12.007

4
Goswami N, Lackner HK, Papousek I, Montani JP, Jezova D, Hinghofer-Szalkay HG.
Does mental arithmetic before head up tilt have an effect on the orthostatic cardiovascular and hormonal responses?
Acta Astronaut. 2011 May-Jun;68(9-10):1589-94.
http://dx.doi.org/10.1016/j.actaastro.2009.09.033

5
Ivanova SM, Brazhe NA, Luneva OG, Yarlikova YV, Labetskaya OI, Parshina EY, Baizhumanov AA, Maksimov GV, Morukov BV.
Physical-chemical properties of plasma membrane and function of erythrocytes of cosmonauts after long-term space flight.
Acta Astronaut. 2011 May-Jun;68(9-10):1517-22.
http://dx.doi.org/10.1016/j.actaastro.2010.06.046
NOTE: ISS results.

6
Pakharukova NA, Pastushkova LKh, Larina IM, Grigoriev AI.
Changes of human serum proteome profile during 7-day “dry” immersion.
Acta Astronaut. 2011 May-Jun;68(9-10):1523-8.
http://dx.doi.org/10.1016/j.actaastro.2009.10.014

7
Fujimoto N, Shibata S, Hastings JL, Carrick-Ranson GC, Bhella PS, Palmer MD, Fu Q, Levine BD.
Effects of pericardial constraint and ventricular interaction on left ventricular hemodynamics in the unloaded heart.
Am J Physiol Heart Circ Physiol. 2011 Mar 11. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21398598
NOTE: From Introduction of paper: “However, it is unclear whether pericardial constraint and/or ventricular interaction influence LV hemodynamics in healthy individuals at low cardiac filling pressure, such as observed during orthostatic stress or the upright position. If so, pericardial constraint could be a previously unrecognized factor that could contribute to orthostatic blood pressure control in otherwise healthy subjects with orthostatic intolerance.”

8
Brothers RM, Keller DM, Wingo JE, Ganio MS, Crandall CG.
Heat-stress induced changes in central venous pressure do not explain inter-individual differences in orthostatic tolerance during heat stress.
J Appl Physiol. 2011 Mar 17. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21415173

9
Fedorowski A, Hedblad B, Engstroem G, Melander O.
Directionality of blood pressure response to standing may determine development of heart failure: Prospective cohort study.
Eur J Heart Fail. 2011 Mar 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21406482

10
Felipe de Vasconcelos T, Sapoval B, Andrade JS Jr, Grotberg JB, Hu Y, Filoche M.
Particle capture into the lung made simple?
J Appl Physiol. 2011 Mar 17. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21415177

11
Rai B, Kaur J, Catalina M, Anand SC, Jacobs R, Teughels W.
Effect of simulated microgravity on salivary and serum oxidants, antioxidants and periodontal status.
J Periodontol. 2011 Mar 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21405937
NOTE: Bed rest study.

12
Ilyin V, Moukhamedieva L, Osipov G, Batov A, Soloviova Z, Mardanov R, Panina Y, Gegenava A.
Non-cultural methods of human microflora evaluation for the benefit of crew medical control in confined habitat.
Acta Astronaut. 2011 May-Jun;68(9-10):1529-36.
http://dx.doi.org/10.1016/j.actaastro.2010.01.013

13
Kotovskaya AR.
The problem of artificial gravity in piloted space exploration missions.
Acta Astronaut. 2011 May-Jun;68(9-10):1608-13.
http://dx.doi.org/10.1016/j.actaastro.2009.11.012

14
Paul PK, Kumar A.
TRAF6 coordinates the activation of autophagy and ubiquitin-proteasome systems in atrophying skeletal muscle.
Autophagy. 2011 May 1;7(5). [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21412053

15
Dupont E, Stevens L, Cochon L, Falempin M, Bastide B, Canu MH.
ERK is involved in the reorganization of somatosensory cortical maps in adult rats submitted to hindlimb unloading.
PLoS One. 2011 Mar 8;6(3):e17564.
http://www.ncbi.nlm.nih.gov/pubmed/21408155
NOTE: This article may be obtained online without charge.

16
Ogneva IV, Ponomareva EV, Kartashkina NL, Altaeva EG, Fokina NM, Kurushin VA, Kozlovskaya IB, Shenkman BS.
Decrease of contractile properties and transversal stiffness of single fibers in human soleus after 7-day “dry” immersion.
Acta Astronaut. 2011 May-Jun;68(9-10):1478-85.
http://dx.doi.org/10.1016/j.actaastro.2010.01.012

17
Kartashkina N, Lomonosova Y, Shevchenko TF, Bugrova AE, Turtikova OV, Kalamkarov GR, Nemirovskaya TL.
Prevention of muscle fibers atrophy during gravitational unloading: The effect of L-arginine administration.
Acta Astronaut. 2011 May-Jun;68(9-10):1486-94.
http://dx.doi.org/10.1016/j.actaastro.2010.02.013

18
Rendina E, Lim YF, Marlow D, Wang Y, Clarke SL, Kuvibidila S, Lucas EA, Smith BJ.
Dietary supplementation with dried plum prevents ovariectomy-induced bone loss while modulating the immune response in C57BL/6J mice.
J Nutr Biochem. 2011 Mar 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21414765

19
Saravi FD.
Asymmetries in hip mineralization in mobile cellular phone users.
J Craniofac Surg. 2011 Mar;22(2):706-10.
http://www.ncbi.nlm.nih.gov/pubmed/21415640
NOTE: Should you alternate locations where you carry your cell phone? This article may be obtained online without charge.

20
Petrov VM.
Using radiation risk for assessment of space radiation hazard.
Acta Astronaut. 2011 May-Jun;68(9-10):1424-9.
http://dx.doi.org/10.1016/j.actaastro.2010.08.034

21
Spillantini P.
Superconducting magnets and mission strategies for protection from ionizing radiation in interplanetary manned missions and interplanetary habitats.
Acta Astronaut. 2011 May-Jun;68(9-10):1430-9.
http://dx.doi.org/10.1016/j.actaastro.2010.07.023

22
Denisov AN, Kuznetsov NV, Nymmik RA, Panasyuk MI, Sobolevsky NM.
Assessment of the radiation environment on the Moon.
Acta Astronaut. 2011 May-Jun;68(9-10):1440-7.
http://dx.doi.org/10.1016/j.actaastro.2010.01.025

23
Petrov VM, Kartashov DA, Akatov YuA, Kolomensky AV, Shurshakov VA.
Comparison of space radiation doses inside the Matroshka-torso phantom installed outside the ISS with the doses in a cosmonaut body in Orlan-M spacesuit during EVA.
Acta Astronaut. 2011 May-Jun;68(9-10):1448-53.
http://dx.doi.org/10.1016/j.actaastro.2010.06.002
NOTE: ISS results.

24
Kim K, Damoiseaux R, Norris AJ, Rivina L, Bradley K, Jung ME, Gatti RA, Schiestl RH, McBride WH.
High throughput screening of small molecule libraries for modifiers of radiation responses.
Int J Radiat Biol. 2011 Mar 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21401317

25
Kornilova LN, Naumov IA, Makarova SM.
Static torsional otolith-cervical-ocular reflex after prolonged exposure to weightlessness and a 7-day immersion.
Acta Astronaut. 2011 May-Jun;68(9-10):1462-8.
http://dx.doi.org/10.1016/j.actaastro.2010.04.016
NOTE: ISS results.

26
Islamov RR, Mishagina EA, Tyapkina OV, Shajmardanova GF, Eremeev AA, Kozlovskaya IB, Nikolskij EE, Grigorjev AI.
Mechanisms of spinal motoneurons survival in rats under simulated hypogravity on Earth.
Acta Astronaut. 2011 May-Jun;68(9-10):1469-77.
http://dx.doi.org/10.1016/j.actaastro.2009.12.001

27
Jenkin MR, Dyde RT, Jenkin HL, Zacher JE, Harris LR.
Perceptual upright: The relative effectiveness of dynamic and static images under different gravity states.
Seeing Perceiving. 2011;24(1):53-64.
http://www.ncbi.nlm.nih.gov/pubmed/21406155
NOTE: Parabolic flight results.

28
Zanelli G, Cappa P, Petrarca M, Berthoz A.
Vestibular and proprioceptive estimation of imposed rotation and spatial updating in standing subjects.
Gait Posture. 2011 Mar 11. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21397506

29
Lopez C, Vibert D, Mast FW.
Can imagined whole-body rotations improve vestibular compensation?
Med Hypotheses. 2011 Mar 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21398044

30
Ehmann B, Balazs L, Fueloep E, Hargitai R, Kabai P, Peley B, Polya T, Vargha A, Laszlo J.
Narrative psychological content analysis as a tool for psychological status monitoring of crews in isolated, confined and extreme settings.
Acta Astronaut. 2011 May-Jun;68(9-10):1560-6.
http://dx.doi.org/10.1016/j.actaastro.2010.01.021

31
Novikova N, Gusev O, Polikarpov N, Deshevaya E, Levinskikh M, Alekseev V, Okuda T, Sugimoto M, Sychev V, Grigoriev A.
Survival of dormant organisms after long-term exposure to the space environment.
Acta Astronaut. 2011 May-Jun;68(9-10):1574-80.
http://dx.doi.org/10.1016/j.actaastro.2010.05.019
NOTE: ISS results.

32
Ishikawa M, Sekine K, Okamura A, Zheng YW, Ueno Y, Koike N, Tanaka J, Taniguchi H.
Reconstitution of hepatic tissue architectures from fetal liver cells obtained from a three-dimensional culture with a rotating wall vessel bioreactor.
J Biosci Bioeng. 2011 Mar 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21402492

33
Guseva K, Thiel M, Booth I, Miller S, Grebogi C, de Moura A.
Collective response of self-organized clusters of mechanosensitive channels.
Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Feb;83(2-1):020901. Epub 2011 Feb 4.
http://www.ncbi.nlm.nih.gov/pubmed/21405810

34
Gautel M.
Cytoskeletal protein kinases: Titin and its relations in mechanosensing.
Pflugers Arch. 2011 Mar 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21416260
NOTE: This article may be obtained online without charge.

35
Soh H, Auh C, Soh WY, Han K, Kim D, Lee S, Rhee Y.
Gene expression changes in Arabidopsis seedlings during short- to long-term exposure to 3-D clinorotation.
Planta. 2011 Mar 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21416242

36
Du F, Li Z, Yang S, Xie B, Liu H.
Electricity generation directly using human feces wastewater for life support system.
Acta Astronaut. 2011 May-Jun;68(9-10):1537-47.
http://dx.doi.org/10.1016/j.actaastro.2009.12.013

37
Tikhomirov AA, Ushakova SA, Velichko VV, Tikhomirova NA, Kudenko YuA, Gribovskaya IV, Gros JB, Lasseur Ch.
Assessment of the possibility of establishing material cycling in an experimental model of the bio-technical life support system with plant and human wastes included in mass exchange.
Acta Astronaut. 2011 May-Jun;68(9-10):1548-54.
http://dx.doi.org/10.1016/j.actaastro.2010.10.005

38
Grigoriev AI, Sinyak YuE, Samsonov NM, Bobe LS, Protasov NN, Andreychuk PO.
Regeneration of water at space stations.
Acta Astronaut. 2011 May-Jun;68(9-10):1567-73.
http://dx.doi.org/10.1016/j.actaastro.2010.05.018
NOTE: Describes water recovery on Salyut and Mir space stations and ISS.

39
Grigoriev AI.
Role of O.G. Gazenko in formation and advancement of space biology and medicine.
Acta Astronaut. 2011 May-Jun;68(9-10):1418-23.
http://dx.doi.org/10.1016/j.actaastro.2009.12.019

40
Deshevaya EA, Shubralova EV, Novikova ND, Borisov VV, Kononenko OD, Polikarpov NA.
Testing and evaluation of a method for locating potentially hazardous sites of eventual microdestruction and detecting marks of ISS RS hull leakage.
Acta Astronaut. 2011 May-Jun;68(9-10):1555-9.
http://dx.doi.org/10.1016/j.actaastro.2010.10.006
NOTE: ISS results.

41
Hellweg CE, Gerzer R, Reitz G.
A new chapter in doctoral candidate training: The Helmholtz Space Life Sciences Research School (SpaceLife).
Acta Astronaut. 2011 May-Jun;68(9-10):1620-7.
http://dx.doi.org/10.1016/j.actaastro.2010.03.014