NASA Spaceline Current Awareness 18 January 2013 (Recent Space Life Science Research Results)

Next list: February 1, 2013
Papers deriving from NASA support:

1
Weaver AS, Zakrajsek AD, Lewandowski BE, Brooker JE, Myers JG Jr.
Predicting head injury risk during International Space Station increments.
Aviat Space Environ Med. 2013 Jan;84(1):38-46.
http://www.ncbi.nlm.nih.gov/pubmed/23304998
(PI: J.G. Myers Jr.)

2
Law J, Mathers CH, Fondy SR, Vanderploeg JM, Kerstman EL.
NASA’s human system risk management approach and its applicability to commercial spaceflight.
Aviat Space Environ Med. 2013 Jan;84(1):68-73.
http://www.ncbi.nlm.nih.gov/pubmed/23305003

3
Cartreine JA, Locke SE, Buckey JC, Sandoval L, Hegel MT.
Electronic problem-solving treatment: Description and pilot study of an interactive media treatment for depression.
J Med Internet Res Res Protoc. 2012 Sep 25;1(2):e11.
http://dx.doi.org/10.2196/resprot.1925
(PI: J.A. Cartreine)
NOTE: This article may be obtained online without charge.

4
Brault JJ, Pizzimenti NM, Dentel JN, Wiseman RW.
Selective inhibition of ATPase activity during contraction alters the activation of p38 MAP kinase isoforms in skeletal muscle.
J Cell Biochem. 2013 Jan 7. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23296747
(PI: R.W. Wiseman)

5
Harnish R, Streeper T, Saeed I, Schreck C, Dannoon S, Slater J, Blecha J, VanBrocklin H, Hernandez-Pampaloni M, Hawkins R, Seo Y, Sayre G, Lang T.
Quantification of changes in skeletal muscle amino acid kinetics in adult humans in response to exercise via positron-emission tomography with L-[methyl-11C] methionine.
J Mol Imaging Dyn. 2012;2:103.
http://dx.doi.org/10.4172/2155-9937.1000103
(PI: T. Lang)
NOTE: This article may be obtained online without charge.

6
Soller BR, Sliwa J, Yang Y, Zou F, Ryan KL, Rickards CA, Convertino VA.
Simultaneous spectroscopic determination of forearm muscle pH and oxygen saturation during simulated haemorrhage.
J Near Infrared Spectrosc. 2012 Mar;20(1):141-50.
http://dx.doi.org/10.1255/jnirs.968
(PI: B.R. Soller)

7
Lan ML, Acharya MM, Tran KK, Bahari-Kashani J, Patel NH, Strnadel J, Giedzinski E, Limoli CL.
Characterizing the radioresponse of pluripotent and multipotent human stem cells.
PLoS One. 2012;7(12):e50048. Epub 2012 Dec 14.
http://www.ncbi.nlm.nih.gov/pubmed/23272054
(PI: C.L. Limoli)
NOTE: This article may be obtained online without charge.

8
Little MP, Azizova TV, Bazyka D, Bouffler SD, Cardis E, Chekin S, Chumak VV, Cucinotta FA, de Vathaire F, Hall P, Harrison JD, Hildebrandt G, Ivanov V, Kashcheev VV, Klymenko SV, Laurent O, Ozasa K, Tapio S, Taylor AM, Tzoulaki I, Vandoolaeghe WL, Wakeford R, Zablotska L, Zhang W, Lipshultz SE.
Comment on “Dose-responses from multi-model inference for the non-cancer disease mortality of atomic bomb survivors” (Radiat. Environ. Biophys (2012) 51:165-178) by Schoellnberger et al.
Radiat Environ Biophys. 2013 Jan 8. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23296519
(PI: F.A. Cucinotta)

9
Peters BT, Brady RA, Bloomberg JJ.
Walking on an oscillating treadmill: Strategies of stride-time adaptation.
Ecol Psychol. 2012;24(4):265-78.
http://dx.doi.org/10.1080/10407413.2012.702637
(PI: J.J. Bloomberg)

10
Basner M, Dinges DF, Mollicone D, Ecker A, Jones CW, Hyder EC, Di Antonio A, Savelev I, Kan K, Goel N, Morukov BV, Sutton JP.
Mars 520-d mission simulation reveals protracted crew hypokinesis and alterations of sleep duration and timing.
Proc Natl Acad Sci U S A. 2013 Jan 7. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23297197
(PI: D.F. Dinges)

11
Roecklein KA, Wong PM, Miller MA, Donofry SD, Kamarck ML, Brainard GC.
Melanopsin, photosensitive ganglion cells, and seasonal affective disorder.
Neurosci Biobehav Rev. 2012 Dec 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23286902
(PI: G.C. Brainard)

12
Vaishampayan P, Moissl-Eichinger C, Pukall R, Schumann P, Sproeer C, Augustus A, Hayden Roberts A, Namba G, Cisneros J, Salmassi T, Venkateswaran K.
Description of Tersicoccus phoenicis gen. nov., sp. nov. isolated from spacecraft assembly clean room environments.
Int J Syst Evol Microbiol. 2012 Dec 7. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23223813

13
Rand E, Periyakaruppan A, Tanaka Z, Zhang DA, Marsh MP, Andrews RJ, Lee KH, Chen B, Meyyappan M, Koehne JE.
A carbon nanofiber based biosensor for simultaneous detection of dopamine and serotonin in the presence of ascorbic acid.
Biosens Bioelectron. 2012 Nov 16;42C:434-8. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23228495

NOTE: The article by PI Michael Delp, “Effects of spaceflight and ground recovery on mesenteric artery and vein constrictor properties in mice” (PubMed ID 23099650), which was included in the October 26, 2012 Current Awareness list as an epub ahead of print, appears in the January 2013 FASEB Journal print issue. The article is highlighted on the cover of the journal with an interesting engraving (by an interesting artist): http://www.fasebj.org/content/27/1.cover-expansion
This is a reminder that this journal features original artwork on its journal covers that can be viewed online. JAMA also features artwork on its covers, although the cover illustrations for this journal are less accessible online.

Other papers of interest:

1
Vandeput S, Widjaja D, Aubert AE, Van Huffel S.
Adaptation of autonomic heart rate regulation in astronauts after spaceflight.
Med Sci Monit. 2013 Jan 4;19:9-17.
http://www.ncbi.nlm.nih.gov/pubmed/23291736
NOTE: ISS results. A personal copy of this article may be obtained online without charge by agreeing to a licensing agreement at the publisher’s site: http://www.medscimonit.com/abstract/index/idArt/883724

2
Blaber AP, Hinghofer-Szalkay H, Goswami N.
Blood volume redistribution during hypovolemia.
Aviat Space Environ Med. 2013 Jan;84(1):59-64.
http://www.ncbi.nlm.nih.gov/pubmed/23305001

3
Villar R, Hughson RL.
Effect of altered arterial perfusion pressure on vascular conductance and muscle blood flow dynamic response during exercise in humans.
J Appl Physiol. 2013 Jan 10. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23305983

4
Moffitt JA, Henry MK, Welliver KC, Jepson AJ, Garnett ER.
Hindlimb unloading results in increased predisposition to cardiac arrhythmias and alters left ventricular connexin43 expression.
Am J Physiol Regul Integr Comp Physiol. 2013 Jan 9. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23302960

5
Kawabe T, Kawabe K, Sapru HN.
Effect of barodenervation on cardiovascular responses elicited from the hypothalamic arcuate nucleus of the rat.
PLoS One. 2012;7(12):e53111. Epub 2012 Dec 27.
http://www.ncbi.nlm.nih.gov/pubmed/23300873
NOTE: This article may be obtained online without charge.

6
Liao Y, Zhang J, Huang Z, Xi Y, Zhang Q, Zhu T, Liu X.
Altered baseline brain activity with 72 h of simulated microgravity – Initial evidence from resting-state fMRI.
PLoS One. 2012;7(12):e52558. Epub 2012 Dec 21.
http://www.ncbi.nlm.nih.gov/pubmed/23285086
NOTE: Bed rest study. This article may be obtained online without charge.

7
Liu Q, Zhou R, Chen S, Tan C.
Effects of head-down bed rest on the executive functions and emotional response.
PLoS One. 2012;7(12):e52160. Epub 2012 Dec 17.
http://www.ncbi.nlm.nih.gov/pubmed/23284916
NOTE: Bed rest study. This article may be obtained online without charge.

8
Meigal AY.
Synergistic action of gravity and temperature on the motor system within the lifespan: A “Baby Astronaut” hypothesis.
Med Hypotheses. 2012 Dec 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23287049

9
Nelson BT, Ding X, Boney-Montoya J, Gerard RD, Kliewer SA, Andrews MT.
Metabolic hormone FGF21 is induced in ground squirrels during hibernation but its overexpression is not sufficient to cause torpor.
PLoS One. 2013;8(1):e53574. Epub 2013 Jan 2.
http://www.ncbi.nlm.nih.gov/pubmed/23301087
NOTE: This article may be obtained online without charge.

10
Flagg SY, Regis DP, Petersen K, Mahon RT.
Interrupted oxygen pre-breathing and decompression outcomes in swine.
Aviat Space Environ Med. 2013 Jan;84(1):12-6.
http://www.ncbi.nlm.nih.gov/pubmed/23304993

11
Wiseman RL, Kelly PT, Swanney MP, McNamara KP, Beckert L.
Hypoxemia in healthy subjects at moderate altitude.
Aviat Space Environ Med. 2013 Jan;84(1):22-6.
http://www.ncbi.nlm.nih.gov/pubmed/23304995

12
Hampson NB, Kregenow DA, Mahoney AM, Kirtland SH, Horan KL, Holm JR, Gerbino AJ.
Altitude exposures during commercial flight: A reappraisal.
Aviat Space Environ Med. 2013 Jan;84(1):27-31.
http://www.ncbi.nlm.nih.gov/pubmed/23304996

13
Ignatescu M, Bryson P, Klingmann C.
Susceptibility of the inner ear structure to shunt-related decompression sickness.
Aviat Space Environ Med. 2012 Dec;83(12):1145-51.
http://www.ncbi.nlm.nih.gov/pubmed/23316542

14
Okuneva AD, Vikhlyantsev IM, Shpagina MD, Rogachevskii VV, Khutzyan SS, Podlubnaya ZA, Grigoriev AI.
Changes in titin and myosin heavy chain isoform composition in skeletal muscles of Mongolian gerbil (Meriones unguiculatus) after 12-day spaceflight.
Biophysics. 2012 Sep;57(5):581-6.
http://link.springer.com/article/10.1134/S0006350912050144
NOTE: Foton M3 results. This paper is a translation in English of the Russian original published in Biofizika. 2012 Sep-Oct;57(5):756-63: http://www.ncbi.nlm.nih.gov/pubmed/23136767

15
Ye F, Mathur S, Liu M, Borst SE, Walter GA, Sweeney HL, Vandenborne K.
Overexpression of IGF-1 attenuates skeletal muscle damage and accelerates muscle regeneration and functional recovery after disuse.
Exp Physiol. 2013 Jan 4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23291913

16
Cornachione AS, Cacao-Benedini LO, Benedini-Elias PC, Martinez EZ, Mattiello-Sverzut AC.
Effects of 40 min of maintained stretch on the soleus and plantaris muscles of rats applied for different periods of time after hindlimb immobilization.
Acta Histochem. 2012 Dec 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23287280

17
Tyapkina OV, Nurullin LF, Rezvyakov PN, Kozlovskaya IB, Nikolsky EE, Islamov RR.
Myelination disorders in the mechanism of hypogravity motor syndrome development.
Biophysics. 2012 Sep;57(5):681-3.
http://link.springer.com/article/10.1134/S0006350912050223
NOTE: This paper is a translation in English of the Russian original published in Biofizika. 2012 Sep-Oct;57(5):876-9: http://www.ncbi.nlm.nih.gov/pubmed/23136782

18
Suetta C, Frandsen U, Jensen L, Jensen MM, Jespersen JG, Hvid LG, Bayer M, Petersson SJ, Schroder HD, Andersen JL, Heinemeier KM, Aagaard P, Schjerling P, Kjaer M.
Aging affects the transcriptional regulation of human skeletal muscle disuse atrophy.
PLoS One. 2012;7(12):e51238. Epub 2012 Dec 19.
http://www.ncbi.nlm.nih.gov/pubmed/23284670
NOTE: This article may be obtained online without charge.

19
Sindler AL, Reyes RA, Chen B, Ghosh P, Gurovich AN, Kang LS, Cardounel AJ, Delp MD, Muller-Delp JM.
Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles.
J Appl Physiol. 2013 Jan 3. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23288555

20
Latouche C, Jowett JB, Carey AL, Bertovic DA, Owen N, Dunstan DW, Kingwell BA.
Effects of breaking up prolonged sitting on skeletal muscle gene expression.
J Appl Physiol. 2012 Dec 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23271697

21
Zwetsloot KA, Childs TE, Gilpin LT, Booth FW.
Non-passaged muscle precursor cells from 32-month old rat skeletal muscle have delayed proliferation and differentiation.
Cell Prolif. 2013 Feb;46(1):45-57. Epub 2012 Dec 21.
http://www.ncbi.nlm.nih.gov/pubmed/23279018
NOTE: This article may be obtained online without charge.

22
Falcai MJ, Louzada MJ, de Paula FJ, Okubo R, Volpon JB.
A modified technique of rat tail suspension for longer periods of observation.
Aviat Space Environ Med. 2012 Dec;83(12):1176-80.
http://www.ncbi.nlm.nih.gov/pubmed/23316547

23
Smriti AA, Miyai K, Ezura Y, Hayata T, Notomi T, Nakamoto T, Pawson T, Noda M.
Nck1 deficiency accelerates unloading-induced bone loss.
J Cell Physiol. 2012 Dec 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23280595

24
Utsunomiya K, Owaki K, Okumura Y, Yano M, Oto T, Suzuki E, Tamura S, Abe T, Kohno S, Ohno A, Hirasaka K, Teshima-Kondoh S, Nikawa T.
An intracellular fragment of osteoactivin formed by ectodomain shedding translocated to the nucleoplasm and bound to RNA binding proteins.
Biosci Biotechnol Biochem. 2012 Dec 23;76(12):2225-9. Epub 2012 Dec 7.
http://www.ncbi.nlm.nih.gov/pubmed/23221696
NOTE: This article may be obtained online without charge.

25
Niu HJ, Wang Q, Wang YX, Li A, Sun LW, Yan Y, Fan F, Li DY, Fan YB.
The study on the mechanical characteristics of articular cartilage in simulated microgravity
Acta Mechanica Sinica. 2012 Oct;28(5):1488-93.
http://dx.doi.org/10.1007/s10409-012-0150-3

26
Boccafoschi F, Mosca C, Ramella M, Valente G, Cannas M.
The effect of mechanical strain on soft (cardiovascular) and hard (bone) tissues: Common pathways for different biological outcomes.
Cell Adh Migr. 2013 Jan 3;7(2). [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23287581

27
Stein EM, Carrelli A, Young P, Bucovsky M, Zhang C, Schrope B, Bessler M, Zhou B, Wang J, Guo XE, McMahon DJ, Silverberg SJ.
Bariatric surgery results in cortical bone loss.
J Clin Endocrinol Metab. 2013 Jan 7. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23295461

28
Khayyeri H, Prendergast PJ.
The emergence of mechanoregulated endochondral ossification in evolution.
J Biomech. 2012 Dec 20. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23261239

29
Narici L, Casolino M, Di Fino L, Larosa M, Larsson O, Picozza P, Zaconte V.
Iron flux inside the International Space Station is measured to be lower than predicted.
Radiat Meas. 2012 Oct;47(10):1030-4.
http://dx.doi.org/10.1016/j.radmeas.2012.07.006
NOTE: ISS results.

30
Derveni M, Allen M, Sawakuchi GO, Yukihara EG, Richter L, Sims MR, Cullen DC.
Survivability of immunoassay reagents exposed to the space radiation environment on board the ESA BIOPAN-6 platform as a prelude to performing immunoassays on Mars.
Astrobiology. 2013 Jan;13(1):92-102. Epub 2013 Jan 3.
http://www.ncbi.nlm.nih.gov/pubmed/23286207
NOTE: FOTON M3 results (BIOPAN-6 platform, Life Marker Chip instrument).

31
Szabo J, Palfalvi JK.
Calibration of solid state nuclear track detectors at high energy ion beams for cosmic radiation measurements: HAMLET results.
Nucl Instrum Methods Phys Res A. 2012 Dec 1;694:193-8.
http://dx.doi.org/10.1016/j.nima.2012.08.010
NOTE: This article reports on a ground research component to ISS research.

32
Chen Y, Reeves G, Friede RH, Thomsen MF, Looper M, Evans D, Sauvaud JA.
LEEM: A new empirical model of radiation-belt electrons in the low-Earth-orbit region.
J Geophys Res Space Phys. 2012 Nov;117:A11205.
http://dx.doi.org/10.1029/2012JA017941

33
Schaue D, Kachikwu EL, McBride WH.
Cytokines in radiobiological responses: A review.
Radiat Res. 2012 Dec;178(6):505-23. Epub 2012 Oct 29.
http://www.ncbi.nlm.nih.gov/pubmed/23106210

34
Becker D, Adhikary A, Tetteh ST, Bull AW, Sevilla MD.
Kr-86 ion-beam irradiation of hydrated DNA: Free radical and unaltered base yields.
Radiat Res. 2012 Dec;178(6):524-37. Epub 2012 Oct 29.
http://www.ncbi.nlm.nih.gov/pubmed/23106211

35
Singh SK, Wu W, Stuschke M, Bockisch A, Iliakis G.
Reduced contribution of thermally-labile sugar lesions to DNA double-strand break formation after exposure to neutrons.
Radiat Res. 2012 Dec;178(6):581-90. Epub 2012 Oct 23.
http://www.ncbi.nlm.nih.gov/pubmed/23088767

36
Williams PT.
Walking and running are associated with similar reductions in cataract risk.
Med Sci Sports Exerc. 2012 Dec 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23274600

37
Kornilova LN, Naumov IA, Azarov KA, Sagalovitch VN.
Gaze control and vestibular-cervical-ocular responses after prolonged exposure to microgravity.
Aviat Space Environ Med. 2012 Dec;83(12):1123-34.
http://www.ncbi.nlm.nih.gov/pubmed/23316540
NOTE: ISS results.

38
McCall AA, Moy JD, DeMayo WM, Puterbaugh SR, Miller DJ, Catanzaro MF, Yates BJ.
Processing of vestibular inputs by the medullary lateral tegmental field of conscious cats: Implications for generation of motion sickness.
Exp Brain Res. 2012 Dec 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23274644

39
Sheldon R.
Tilt table testing and implantable loop recorders for syncope.
Cardiol Clin. 2013 Feb;31(1):67-74.
http://www.ncbi.nlm.nih.gov/pubmed/23217688
NOTE: The topic of this issue is syncope.

40
Lee AT, Schrumpf MA, Choi D, Meyers KN, Patel R, Wright TM, Hotchkiss RN, Daluiski A.
The influence of gravity on the unstable elbow.
J Shoulder Elbow Surg. 2013 Jan;22(1):81-7.
http://www.ncbi.nlm.nih.gov/pubmed/23237692
NOTE: This article may be obtained online without charge.

41
Sulpizio V, Committeri G, Lambrey S, Berthoz A, Galati G.
Selective role of lingual/parahippocampal gyrus and retrosplenial complex in spatial memory across viewpoint changes relative to the environmental reference frame.
Behav Brain Res. 2012 Dec 26;242C:62-75. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23274842

42
On Orbit and Beyond: Psychological Perspectives on Human Spaceflight.
Vakoch DA (Ed.)
Springer; Series: Space Technology Library, Vol. 29, 2013, 317 p.
http://www.springer.com/engineering/mechanical+engineering/book/978-3-64…
NOTE: This book is the second, expanded edition to: “Psychology of Space Exploration: Contemporary Research in Historical Perspective” (available online without charge at: http://history.nasa.gov/SP-4411.pdf )
The Table of Contents, Preface, and Chapter 2 of the second edition are available online without charge.

43
Fraser W.
Mechanobiology.
Aviat Space Environ Med. 2012 Dec;83(12):1190-1.
http://www.ncbi.nlm.nih.gov/pubmed/23316551
NOTE: This article may be obtained online without charge at: http://www.ingentaconnect.com/content/asma/asem

44
Burridge K, Wittchen ES.
The tension mounts: Stress fibers as force-generating mechanotransducers.
J Cell Biol. 2013 Jan 7;200(1):9-19.
http://www.ncbi.nlm.nih.gov/pubmed/23295347
NOTE: This article may be obtained online without charge.

45
Leerberg JM, Yap AS.
Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions.
Protoplasma. 2012 Dec 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23274283

46
Bharadwaj R, Roy M, Ohyama T, Sivan-Loukianova E, Delannoy M, Lloyd TE, Zlatic M, Eberl DF, Kolodkin AL.
Cbl-associated protein regulates assembly and function of two tension-sensing structures in Drosophila.
Development. 2013 Feb 1;140(3):627-38.
http://www.ncbi.nlm.nih.gov/pubmed/23293294

47
Kerstein PC, Jacques-Fricke BT, Rengifo J, Mogen BJ, Williams JC, Gottlieb PA, Sachs F, Gomez TM.
Mechanosensitive TRPC1 channels promote calpain proteolysis of talin to regulate spinal axon outgrowth.
J Neurosci. 2013 Jan 2;33(1):273-85.
http://www.ncbi.nlm.nih.gov/pubmed/23283340
NOTE: This article may be obtained online without charge via PubMed Central.

48
Dumais J.
Beyond the sine law of plant gravitropism.
Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):391-2. Epub 2012 Dec 28.
http://www.ncbi.nlm.nih.gov/pubmed/23275295
NOTE: This is a comment on an article by Bastien et al. that appeared in the previous Current Awareness list (PMID: 23236182). The Bastien article is featured on the cover of PNAS: http://www.pnas.org/content/110/2.cover-expansion

49
Lupini A, Araniti F, Sunseri F, Abenavoli MR.
Gravitropic response induced by coumarin: Evidences of ROS distribution involvement.
Plant Signal Behav. 2013 Jan 8;8(2). [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23299434
NOTE: This article may temporarily be obtained online without charge.

50
Kurusu T, Kuchitsu K, Nakano M, Nakayama Y, Iida H.
Plant mechanosensing and Ca(2+) transport.
Trends Plant Sci. 2013 Jan 3. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23291244