NASA Spaceline Current Awareness 12 October 2012 (Recent Space Life Science Research Results)

Next list: October 26, 2012

Papers deriving from NASA support:

1
Carrick-Ranson GC, Hastings JL, Bhella PS, Shibata S, Levine BD.
The effect of exercise training on left ventricular relaxation and diastolic suction at rest and during orthostatic stress after bed rest.
Exp Physiol. 2012 Sep 21. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23002243
(PI: B.D. Levine)
NOTE: Bed rest study.

2
Shirazi-Fard Y, Kupke JS, Bloomfield SA, Hogan HA.
Discordant recovery of bone mass and mechanical properties during prolonged recovery from disuse.
Bone. 2012 Sep 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23017660
(PI: H.A. Hogan)
NOTE: The results are compared with astronaut space flight data.

3
Ryder JW, Buxton RE, Goetchius E, Scott-Pandorf M, Hackney KJ, Fiedler J, Ploutz-Snyder RJ, Bloomberg JJ, Ploutz-Snyder LL.
Influence of muscle strength to weight ratio on functional task performance.
Eur J Appl Physiol. 2012 Sep 26. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23011123
(PIs: J.J. Bloomberg, L.L. Ploutz-Snyder)
NOTE: This study includes Shuttle results.

4
Stowe RP, Peek MK, Cutchin MP, Goodwin JS.
Reactivation of herpes simplex virus type 1 is associated with cytomegalovirus and age.
J Med Virol. 2012 Nov;84(11):1797-802.
http://www.ncbi.nlm.nih.gov/pubmed/22997083
(PI: R.P. Stowe)

5
Li Y, Qian H, Wang Y, Cucinotta FA.
A stochastic model of DNA fragments rejoining.
PLoS One. 2012;7(9):e44293. Epub 2012 Sep 13.
http://www.ncbi.nlm.nih.gov/pubmed/23028515
(PIs: Y. Wang, F.A. Cucinotta)
NOTE: This article may be obtained online without charge.

6
Zhou Y, Ni H, Li M, Sanzari JK, Diffenderfer ES, Lin L, Kennedy AR, Weissman D.
Effect of solar particle event radiation and hindlimb suspension on gastrointestinal tract bacterial translocation and immune activation.
PLoS One. 2012;7(9):e44329. Epub 2012 Sep 19.
http://www.ncbi.nlm.nih.gov/pubmed/23028522
(PI: A.R. Kennedy/D. Weissman/Center of Acute Radiation Research)
NOTE: This article may be obtained online without charge.

7
Yeiser L, Villasana L, Raber J.
ApoE isoform modulates effects of cranial (56)Fe irradiation on spatial learning and memory in the water maze.
Behav Brain Res. 2012 Sep 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23018124
(PIs: J. Raber; G. Nelson/J. Raber/NSCOR)

8
Rithidech KN, Tungjai M, Reungpatthanaphong P, Honikel L, Simon SR.
Attenuation of oxidative damage and inflammatory responses by apigenin given to mice after irradiation.
Mutat Res. 2012 Aug 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23010607
(PI: K.N. Rithidech)

9
Selva P, Oman CM.
Relationships between Observer and Kalman Filter models for human dynamic spatial orientation.
J Vestib Res. 2012 Jan 1;22(2-3):69-80.
http://www.ncbi.nlm.nih.gov/pubmed/23000607
(PI: C.M. Oman)
NOTE: This article and the following five articles and four articles in the other section derive from the Eighth Symposium on the Role of the Vestibular Organs in Space Exploration, held in Houston on April 2011. An introductory article describing the Symposium is available online without charge: http://dx.doi.org/10.3233/VES-2012-0452

10
Cohen HS, Mulavara AP, Peters BT, Sangi-Haghpeykar H, Bloomberg JJ.
Tests of walking balance for screening vestibular disorders.
J Vestib Res. 2012 Jan 1;22(2-3):95-104.
http://www.ncbi.nlm.nih.gov/pubmed/23000609
(PIs: A.P. Mulavara, J.J. Bloomberg)

11
Oman CM.
Are evolutionary hypotheses for motion sickness “just-so” stories?
J Vestib Res. 2012 Jan 1;22(2-3):117-27.
http://www.ncbi.nlm.nih.gov/pubmed/23000611
(PI: C.M. Oman)

12
Shelhamer M, Beaton K.
Pre-flight sensorimotor adaptation protocols for suborbital flight.
J Vestib Res. 2012 Jan 1;22(2-3):139-44.
http://www.ncbi.nlm.nih.gov/pubmed/23000613
(PI: M. Shelhamer)
NOTE: This article is about preparations for commercial suborbital flights.

13
Peters BT, Mulavara AP, Cohen HS, Sangi-Haghpeykar H, Bloomberg JJ.
Dynamic visual acuity testing for screening patients with vestibular impairments.
J Vestib Res. 2012 Jan 1;22(2-3):145-51.
http://www.ncbi.nlm.nih.gov/pubmed/23000614
(PIs: A.P. Mulavara, J.J. Bloomberg)

14
Mulavara AP, Ruttley T, Cohen HS, Peters BT, Miller C, Brady R, Merkle L, Bloomberg JJ.
Vestibular-somatosensory convergence in head movement control during locomotion after long-duration space flight.
J Vestib Res. 2012 Jan 1;22(2-3):153-66.
http://www.ncbi.nlm.nih.gov/pubmed/23000615
(PI: J.J. Bloomberg)
NOTE: This study includes ISS results.

15
Buccello-Stout RR, Cromwell RL, Bloomberg JJ, Whorton EB.
Effects of sensorimotor adaptation training on head stability movement control in response to a lateral perturbation in older adults.
J Aging Phys Act. 2012 Sep 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23006335
(PIs: R.R. Buccello-Stout, NASA Graduate Student Researcher Program; J.J. Bloomberg)

16
Barger LK, Sullivan JP, Vincent AS, Fiedler ER, McKenna LM, Flynn-Evans EE, Gilliland K, Sipes WE, Smith PH, Brainard GC, Lockley SW.
Learning to live on a Mars day: Fatigue countermeasures during the Phoenix Mars Lander mission.
Sleep. 2012 Oct 1;35(10):1423-35.
http://www.ncbi.nlm.nih.gov/pubmed/23024441
(PIs: L.K. Barger, G.C. Brainard, S.W. Lockley)
NOTE: Press release: http://www.brighamandwomens.org/about_bwh/publicaffairs/news/pressreleas…

17
Scheer FA, Morris CJ, Garcia JI, Smales C, Kelly EE, Marks J, Malhotra A, Shea SA.
Repeated melatonin supplementation improves sleep in hypertensive patients treated with beta-blockers: A randomized controlled trial.
Sleep. 2012 Oct 1;35(10):1395-402.
http://www.ncbi.nlm.nih.gov/pubmed/23024438
(PI: C.J. Morris, NSBRI Postdoctoral Fellowship Program)

18
Wessendorf A, Newman D.
Dynamic understanding of human skin movement and strain-field analysis.
IEEE Trans Biomed Eng. 2012 Sep 4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22961262
(PI: D. Newman)

19
Blancaflor EB.
Regulation of plant gravity sensing and signaling by the actin cytoskeleton.
Am J Bot. 2012 Sep 21. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23002165
NOTE: This article may be obtained online without charge.
(PI: E.B. Blancaflor)

20
Mattioda A, Cook A, Ehrenfreund P, Quinn R, Ricco AJ, Squires D, Bramall N, Bryson K, Chittenden J, Minelli G, Agasid E, Allamandola L, Beasley C, Burton R, Defouw G, Diaz-Aguado M, Fonda M, Friedericks C, Kitts C, Landis D, McIntyre M, Neumann M, Rasay M, Ricks R, Salama F, Santos O, Schooley A, Yost B, Young A.
The O/OREOS mission: First science data from the Space Environment Viability of Organics (SEVO) payload.
Astrobiology. 2012 Sep;12(9):841-53.
http://www.ncbi.nlm.nih.gov/pubmed/22984872
NOTE: O/OREOS nanosatellite results. This article may be obtained online without charge.

Other papers of interest:

1
Strewe C, Feuerecker M, Nichiporuk I, Kaufmann I, Hauer D, Morukov B, Schelling G, Chouker A.
Effects of parabolic flight and spaceflight on the endocannabinoid system in humans.
Rev Neurosci. 2012 Sep 28;0(0):1-8. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23023882
NOTE: Parabolic flight and ISS results.

2
Chladekova L, Czippelova B, Turianikova Z, Tonhajzerova I, Calkovska A, Baumert M, Javorka M.
Multiscale time irreversibility of heart rate and blood pressure variability during orthostasis.
Physiol Meas. 2012 Oct;33(10):1747-56. Epub 2012 Sep 26.
http://www.ncbi.nlm.nih.gov/pubmed/23010992

3
Mager DR.
Orthostatic hypotension: Pathophysiology, problems, and prevention.
Home Healthc Nurse. 2012 Oct;30(9):525-30.
http://www.ncbi.nlm.nih.gov/pubmed/23026987
NOTE: This article, which has a clinical focus, may be obtained online without charge. Go to the publisher’s abstract (Lippincott site) and click on full text or pdf under Article Tools on the right side.

4
Liakopoulos V, Leivaditis K, Eleftheriadis T, Dombros N.
The kidney in space.
Int Urol Nephrol. 2012 Sep 22. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23001611

5
Gong Y, Chen L, Shen B, Ma Q.
[Electrical impedance spectroscopy for evaluation of the influence of simulated weightlessness on the electrical properties of rat blood]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2012 Aug;29(4):653-7, 662. Chinese.
http://www.ncbi.nlm.nih.gov/pubmed/23016410

6
Horie M, Kambara T, Kuroda E, Miki T, Honma Y, Aoki S, Morimoto Y.
[Possibility of exacerbation of allergy by lunar regolith]
J UOEH. 2012 Sep 1;34(3):237-43. Japanese.
http://www.ncbi.nlm.nih.gov/pubmed/23035343

7
Liu J, Peng Y, Cui Z, Wu Z, Qian A, Shang P, Qu L, Li Y, Liu J, Long J.
Depressed mitochondrial biogenesis and dynamic remodeling in mouse tibialis anterior and gastrocnemius induced by 4-week hindlimb unloading.
IUBMB Life. 2012 Sep 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23024034

8
Mukai R, Horikawa H, Fujikura Y, Kawamura T, Nemoto H, Nikawa T, Terao J.
Prevention of disuse muscle atrophy by dietary ingestion of 8-prenylnaringenin in denervated mice.
PLoS One. 2012;7(9):e45048. Epub 2012 Sep 19.
http://www.ncbi.nlm.nih.gov/pubmed/23028754
NOTE: This article may be obtained online without charge.

9
Lammers G, Poelkens F, Duijnhoven NT, Pardoel EM, Hoenderop JG, Thijssen DH, Hopman MT.
The expression of genes involved in fatty acid transport and insulin signaling is altered by physical inactivity and exercise training in human skeletal muscle.
Am J Physiol Endocrinol Metab. 2012 Sep 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23011062

10
Hong P, Chen K, Huang B, Liu M, Cui M, Rozenberg I, Chaqour B, Pan X, Barton ER, Jiang XC, Siddiqui MA.
HEXIM1 controls satellite cell expansion after injury to regulate skeletal muscle regeneration.
J Clin Invest. 2012 Oct 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23023707
NOTE: This article may be obtained online without charge.

11
Di Giminiani R, Masedu F, Tihanyi J, Scrimaglio R, Valenti M.
The interaction between body position and vibration frequency on acute response to whole body vibration.
J Electromyogr Kinesiol. 2012 Sep 20. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23000688

12
Klein-Nulend J, Bacabac RG, Bakker AD.
Mechanical loading and how it affects bone cells: The role of the osteocyte cytoskeleton in maintaining our skeleton.
Eur Cell Mater. 2012 Sep 24;24:278-91.
http://www.ncbi.nlm.nih.gov/pubmed/23007912
NOTE: This article may be obtained online without charge.

13
Bleicher M, Burigo L, Durante M, Herrlitz M, Kraemer M, Mishustin I, Mueller I, Natale F, Pshenichnov I, Schramm S, Taucher-Scholz G, Waelzlein C.
Nanolesions induced by heavy ions in human tissues: Experimental and theoretical studies.
Beilstein J Nanotechnol. 2012;3:556-63. Epub 2012 Jul 25.
http://www.ncbi.nlm.nih.gov/pubmed/23019551
NOTE: This article may be obtained online without charge.

14
Rana P, Khan AR, Modi S, Kumar BS, Javed S, Tripathi RP, Khushu S.
Altered brain metabolism after whole body irradiation in mice: A preliminary in vivo (1)H MRS study.
Int J Radiat Biol. 2012 Oct 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23020784

15
Jella KK, Garcia A, McClean B, Byrne HJ, Lyng FM.
Cell death pathways in directly irradiated cells and cells exposed to medium from irradiated cells.
Int J Radiat Biol. 2012 Oct 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23020735

16
Smith RW, Wang J, Schueltke E, Seymour CB, Braeuer-Krisch E, Laissue JA, Blattmann H, Mothersill CE.
Proteomic changes in the rat brain induced by homogenous irradiation and by the bystander effect resulting from high energy synchrotron X-ray microbeams.
Int J Radiat Biol. 2012 Sep 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23004567

17
Butterworth KT, McGarry CK, Clasie B, Carabe-Fernandez A, Schuemann J, Depauw N, Tang S, McMahon SJ, Schettino G, O’Sullivan JM, Lu HM, Kooy H, Paganetti H, Hounsell AR, Held KD, Prise KM.
Relative biological effectiveness (RBE) and out-of-field cell survival responses to passive scattering and pencil beam scanning proton beam deliveries.
Phys Med Biol. 2012 Oct 21;57(20):6671-80. Epub 2012 Oct 1.
http://www.ncbi.nlm.nih.gov/pubmed/23022765

18
Nambiar S, Yeow JT.
Polymer-composite materials for radiation protection.
ACS Appl Mater Interfaces. 2012 Sep 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23009182

19
de Winkel KN, Clement G, Groen EL, Werkhoven PJ.
The perception of verticality in lunar and Martian gravity conditions.
Neurosci Lett. 2012 Sep 19. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22999922
NOTE: Parabolic flight results.

20
Zeredo JL, Toda K, Matsuura M, Kumei Y.
Behavioral responses to partial-gravity conditions in rats.
Neurosci Lett. 2012 Oct 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23036524
NOTE: Parabolic flight results.

21
Dunlap MD, Spoon CE, Grant JW.
Experimental measurement of utricle dynamic response\m{1}.
J Vestib Res. 2012 Jan 1;22(2-3):57-68.
http://www.ncbi.nlm.nih.gov/pubmed/23000606

22
Holly JE, Harmon SM.
Sensory conflict compared in microgravity, artificial gravity, motion sickness, and vestibular disorders.
J Vestib Res. 2012 Jan 1;22(2-3):81-94.
http://www.ncbi.nlm.nih.gov/pubmed/23000608

23
Guterman PS, Allison RS, Palmisano S, Zacher JE.
Influence of head orientation and viewpoint oscillation on linear vection.
J Vestib Res. 2012 Jan 1;22(2-3):105-16.
http://www.ncbi.nlm.nih.gov/pubmed/23000610

24
Young LR, Bernard-Demanze L, Dumitrescu M, Magnan J, Borel L, Lacour M.
Postural performance of vestibular loss patients under increased postural threat.
J Vestib Res. 2012 Jan 1;22(2-3):129-38.
http://www.ncbi.nlm.nih.gov/pubmed/23000612

25
Valko Y, Lewis RF, Priesol AJ, Merfeld DM.
Vestibular labyrinth contributions to human whole-body motion discrimination.
J Neurosci. 2012 Sep 26;32(39):13537-42.
http://www.ncbi.nlm.nih.gov/pubmed/23015443

26
Hills PJ, Sullivan AJ, Pake JM.
Aberrant first fixations when looking at inverted faces in various poses: The result of the centre-of-gravity effect?
Br J Psychol. 2012 Nov;103(4):520-38. Epub 2012 Jan 4.
http://www.ncbi.nlm.nih.gov/pubmed/23034110

27
Tarnutzer AA, Schuler JR, Bockisch CJ, Straumann D.
Hysteresis of haptic vertical and straight ahead in healthy human subjects.
BMC Neurosci. 2012 Sep 22;13:114. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22998034
NOTE: This article may be obtained online without charge.

28
Iwasaki S, Chihara Y, Egami N, Fujimoto C, Murofushi T, Yamasoba T.
Different effects of head tilt on ocular vestibular-evoked myogenic potentials in response to bone-conducted vibration and air-conducted sound.
Exp Brain Res. 2012 Sep 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23007722

29
Porte Y, Morel JL.
Learning on Jupiter, learning on the Moon: The dark side of the G-force. Effects of gravity changes on neurovascular unit and modulation of learning and memory.
Front Behav Neurosci. 2012;6:64. Epub 2012 Sep 24.
http://www.ncbi.nlm.nih.gov/pubmed/23015785
NOTE: This article may be obtained online without charge.

30
Lo JC, Groeger JA, Santhi N, Arbon EL, Lazar AS, Hasan S, von Schantz M, Archer SN, Dijk DJ.
Effects of partial and acute total sleep deprivation on performance across cognitive domains, individuals and circadian phase.
PLoS One. 2012;7(9):e45987. Epub 2012 Sep 24.
http://www.ncbi.nlm.nih.gov/pubmed/23029352
NOTE: This article may be obtained online without charge.

31
Lim AS, Chang AM, Shulman JM, Raj T, Chibnik LB, Cain SW, Rothamel K, Benoist C, Myers AJ, Czeisler CA, Buchman AS, Bennett DA, Duffy JF, Saper CB, De Jager PL.
A common polymorphism near PER1 and the timing of human behavioral rhythms.
Ann Neurol. 2012 Sep;72(3):324-34.
http://www.ncbi.nlm.nih.gov/pubmed/23034908

32
Wu C, Li L, Wei H, Wu Z, Jiang Q, Zhang S.
[Tail-suspended model simulating mouse oocytes maturation inhibited with microgravity]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2012 Aug;29(4):687-90, 696. Chinese.
http://www.ncbi.nlm.nih.gov/pubmed/23016417

33
Sudo M, Osakabe M.
Geotaxis and leaf-surface preferences mitigate negative effects of a predatory mite on an herbivorous mite.
Exp Appl Acarol. 2012 Sep 26. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/23011108

34
Saei AA, Omidi AA, Barzegari A.
Screening and genetic manipulation of green organisms for establishment of biological life support systems in space.
Bioengineered. 2012;4(2). [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22992434

35
Verma D, Ye N, Meng F, Sachs F, Rahimzadeh J, Hua SZ.
Interplay between cytoskeletal stresses and cell adaptation under chronic flow.
PLoS One. 2012;7(9):e44167. Epub 2012 Sep 19.
http://www.ncbi.nlm.nih.gov/pubmed/23028495
NOTE: This article may be obtained online without charge.

36
Castillo AB, Blundo JT, Chen JC, Lee KL, Yereddi NR, Jang E, Kumar S, Tang WJ, Zarrin S, Kim JB, Jacobs CR.
Focal adhesion kinase plays a role in osteoblast mechanotransduction in vitro but does not affect load-induced bone formation in vivo.
PLoS One. 2012;7(9):e43291. Epub 2012 Sep 21.
http://www.ncbi.nlm.nih.gov/pubmed/23028449
NOTE: This article may be obtained online without charge.

37
Kraznov IB.
[Neuromediators and neurotransmitters in the bone tissue remodeling]
Aviakosm Ekolog Med. 2012 Mar-Apr;46(2):3-8. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/22953533

38
Zinkin VN, Bogomolov AV, Akhmetzyanov IM, Sheshegov PM.
[Aviation noise: Specifics of the biological action and protection]
Aviakosm Ekolog Med. 2012 Mar-Apr;46(2):9-16. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/22953534

39
Ushakov IB, Fedorov VP, Afanasiev RV.
[Neuromorphological effects of low doses of ionizing radiation]
Aviakosm Ekolog Med. 2012 Mar-Apr;46(2):16-20. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/22953535

40
Barantseva MYu, Tatarkin SV, Mukhamedieva LN, Shafirkin AV, Ivanova SM.
[Shifts in the mice blood-forming system and energy exchange of erythrocytes due to chronic exposure to chemical agents (acetone, ethanol, acetaldehyde) and radiation in concentrations and doses modeling the conditions in extended orbital mission]
Aviakosm Ekolog Med. 2012 Mar-Apr;46(2):21-8. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/22953536

41
Zaripova YuR, Meigal AYu.
[Neuromuscular status of children of different gestational age on the stage of transition from intrauterine immersion to the Earth’s gravity]
Aviakosm Ekolog Med. 2012 Mar-Apr;46(2):29-33. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/22953537

42
Markin AA, Zhuravleva OA, Morukov BV, Koloteva MI, Zabolotskaya IV, Vostrikova LV, Kuzichkin DS.
[Lipid peroxidation and the antioxidant defense system in hypergravity-exposed human]
Aviakosm Ekolog Med. 2012 Mar-Apr;46(2):34-6. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/22953538

43
Patushkova LKh, Valeeva OA, Kononikhin AS, Nikolaev EN, Popov IA, Larina IM, Dobrokhotov IV, Ivanisenko VA, Tiys ES, Kolchanov NA.
[Analysis of protein ratios based on the studies of human urine proteome in an experiment with 105-day isolation]
Aviakosm Ekolog Med. 2012 Mar-Apr;46(2):37-43. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/22953539

44
Piruzian LA, Protasova OV, Maksimova IA, Morukov BV, Protasov SV, Ushakov IB.
[Calcium and phosphorus content of human organism during 105-day isolation]
Aviakosm Ekolog Med. 2012 Mar-Apr;46(2):43-7. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/22953540

45
Ivanov DG, Podkovkin VG.
[Morphofunctional characteristics of rats’ bone tissue after acute and subchronic emotional stress]
Aviakosm Ekolog Med. 2012 Mar-Apr;46(2):50-5. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/22953542