NASA Spaceline Current Awareness 1 April 2011 (Recent Space Life Science Research Results)

Papers deriving from NASA support:

1
Asaithamby A, Hu B, Delgado O, Ding LH, Story MD, Minna JD, Shay JW, Chen DJ.
Irreparable complex DNA double-strand breaks induce chromosome breakage in organotypic three-dimensional human lung epithelial cell culture.
Nucleic Acids Res. 2011 Mar 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21421565
(PIs: D.J. Chen; J.D. Minna/A. Asaithamby/M.D. Story/J.W. Shay/D.J. Chen/NSCOR)
NOTE: This article may be obtained online without charge.

2
Templin T, Paul S, Amundson SA, Young EF, Barker CA, Wolden SL, Smilenov LB.
Radiation-induced micro-RNA expression changes in peripheral blood cells of radiotherapy patients.
Int J Radiat Oncol Biol Phys. 2011 Mar 21. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21420249
(PI: L.B. Smilenov)

3
Rabin BM, Joseph JA, Shukitt-Hale B, Carrihill-Knoll KL.
Interaction between age of irradiation and age of testing in the disruption of operant performance using a ground-based model for exposure to cosmic rays.
Age (Dordr). 2011 Mar 22. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21424788
(PI: B.M. Rabin)

4
Jahn-Eimermacher A, Lasarzik I, Raber J.
Statistical analysis of latency outcomes in behavioral experiments.
Behav Brain Res. 2011 Mar 11. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21397635
(PI: J. Raber)

5
Rader AA, Oman CM, Merfeld DM.
Perceived tilt and translation during variable-radius swing motion with congruent or conflicting visual and vestibular cues.
Exp Brain Res. 2011 Apr;210(2):173-84. Epub 2011 Mar 19.
http://www.ncbi.nlm.nih.gov/pubmed/21424258
(PI: D.M. Merfeld)

Other papers of interest:

1
Bonjour J, Bringard A, Antonutto G, Capelli C, Linnarsson D, Pendergast DR, Ferretti G.
Effects of acceleration in the G(z) axis on human cardiopulmonary responses to exercise.
Eur J Appl Physiol. 2011 Mar 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21437604
NOTE: Includes Mir results.

2
Belavy DL, Seibel MJ, Roth HJ, Armbrecht G, Rittweger J, Felsenberg D.
The effects of bed rest and counter measure exercise on the endocrine system in male adults – evidence for immobilization induced reduction in SHBG levels.
J Endocrinol Invest. 2011 Mar 21. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21422800
NOTE: Berlin Bed Rest Study.

3
Trivelloni P, Berrettini U.
[Cardiovascular consequences of aerobic maneuvers]
G Ital Cardiol (Rome). 2010 Oct;11(10 Suppl 1):126S-9S. Italian.
http://www.ncbi.nlm.nih.gov/pubmed/21416842

4
Hinghofer-Szalkay H, Lackner HK, Roessler A, Narath B, Jantscher A, Goswami N.
Hormonal and plasma volume changes after presyncope.
Eur J Clin Invest. 2011 Mar 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21434895

5
Furukawa T, Maggi R, Solano A, Croci F, Brignole M.
Effect of clinical triggers on positive responses to tilt-table testing potentiated with nitroglycerin or clomipramine.
Am J Cardiol. 2011 Mar 21. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21420055

6
Saxon LK, Jackson B, Sugiyama T, Lanyon LE, Price JS.
Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it.
Bone. 2011 Mar 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21419885

7
Keyak JH, Sigurdsson S, Karlsdottir G, Oskarsdottir D, Sigmarsdottir A, Zhao S, Kornak J, Harris TB, Sigurdsson G, Jonsson BY, Siggeirsdottir K, Eiriksdottir G, Gudnason V, Lang TF.
Male-female differences in the association between incident hip fracture and proximal femoral strength: A finite element analysis study.
Bone. 2011 Mar 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21419886

8
Daoussis D, Andonopoulos AP.
The emerging role of Dickkopf-1 in bone biology: Is it the main switch controlling bone and joint remodeling?
Semin Arthritis Rheum. 2011 Mar 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21435697

9
Payne JB, Stoner JA, Lee HM, Nummikoski PV, Reinhardt RA, Golub LM.
Serum bone biomarkers and oral/systemic bone loss in humans.
J Dent Res. 2011 Mar 21. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21422479

10
Washington TA, White JP, Davis JM, Wilson LB, Lowe LL, Sato S, Carson JA.
Skeletal muscle mass recovery from atrophy in IL-6 knockout mice.
Acta Physiol (Oxf). 2011 Mar 19. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21418148

11
Salmanpour A, Brown LJ, Steinback CD, Usselman CW, Goswami R, Shoemaker JK.
Relationship between size and latency of action potentials in human muscle sympathetic nerve activity.
J Neurophysiol. 2011 Mar 23. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21430271

12
Hurley BF, Hanson ED, Sheaff AK.
Strength training as a countermeasure to aging muscle and chronic disease.
Sports Med. 2011 Apr 1;41(4):289-306.
http://www.ncbi.nlm.nih.gov/pubmed/21425888

13
Maalouf M, Durante M, Foray N.
Biological effects of space radiation on human cells: History, advances and outcomes.
J Radiat Res (Tokyo). 2011;52(2):126-46.
http://www.ncbi.nlm.nih.gov/pubmed/21436608
NOTE: This article, an extensive review of the effects of space radiation from a historical perspective, may be obtained online without charge.

14
Hrushesky WJ, Sothern RB, Du-Quiton J, Quiton DF, Rietveld W, Boon ME.
Sunspot dynamics are reflected in human physiology and pathophysiology.
Astrobiology. 2011 Mar;11(2):93-103. Epub 2011 Mar 10.
http://www.ncbi.nlm.nih.gov/pubmed/21391821
NOTE: This article may be obtained online without charge.

15
Pham QC, Berthoz A, Hicheur H.
Invariance of locomotor trajectories across visual and gait direction conditions.
Exp Brain Res. 2011 Apr;210(2):207-15. Epub 2011 Mar 25.
http://www.ncbi.nlm.nih.gov/pubmed/21437633

16
Ushio M, Minor LB, Della Santina CC, Lasker DM.
Unidirectional rotations produce asymmetric changes in horizontal VOR gain before and after unilateral labyrinthectomy in macaques.
Exp Brain Res. 2011 Mar 23. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21431432

17
Tia B, Saimpont A, Paizis C, Mourey F, Fadiga L, Pozzo T.
Does observation of postural imbalance induce a postural reaction?
PLoS One. 2011 Mar 15;6(3):e17799.
http://www.ncbi.nlm.nih.gov/pubmed/21423622
NOTE: This article may be obtained online without charge.

18
Dornmayr-Pfaffenhuemer M, Legat A, Schwimbersky K, Fendrihan S, Stan-Lotter H.
Responses of haloarchaea to simulated microgravity.
Astrobiology. 2011 Mar 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21417742
NOTE: This article may be obtained online without charge.

19
Majumder S, Siamwala JH, Srinivasan S, Sinha S, Sridhara SR, Soundararajan G, Seerapu HR, Chatterjee S.
Simulated microgravity promoted differentiation of Bipotential Murine Oval Liver stem cells by modulating BMP4/Notch1 signaling.
J Cell Biochem. 2011 Mar 23. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21433062

20
Kresh JY, Chopra A.
Intercellular and extracellular mechanotransduction in cardiac myocytes.
Pflugers Arch. 2011 Mar 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21437600

21
Zhang CB, Yuan GZ, Wang J, Pan GT, Rong TZ, Cao MJ.
[Genetic analysis of maize cytoplasmic male sterile mutants obtained by space flight]
Yi Chuan. 2011 Feb;33(2):175-81. Chinese.
http://www.ncbi.nlm.nih.gov/pubmed/21377975
NOTE: Chinese satellite results.