NASA Spaceline 9 December 2005 Current Space Life Science Awareness
PubMed’s abstract is linked when available and each will open in a new window.
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Xiao X, Grenon SM, Kim C, Sheynberg N, Hurwitz S, Williams GH, Cohen RJ.
Bed rest effects on human calf hemodynamics and orthostatic intolerance: a model-based analysis.
Aviat Space Environ Med. 2005 Nov;76(11):1037-45.
(HSR&T PIs: G.H. Williams, R.J. Cohen))
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Hinghofer-Szalkay HG, Rossler A, Evans JM, Stenger MB, Moore FB, Knapp CF.
Circulatory galanin levels increase several fold with intense orthostatic challenge in healthy humans.
J Appl Physiol. 2005 Dec 1; [Epub ahead of print]
Note:
ARC’s Human Powered Centrifuge was used in the study.
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Brown M, Foley A, Ferreria JA.
Ovariectomy, hindlimb unweighting, and recovery effects on skeletal muscle in adult rats.
Aviat Space Environ Med. 2005 Nov;76(11):1012-8.
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Kandarian SC, Jackman RW.
Intracellular signaling during skeletal muscle atrophy.
Muscle Nerve. 2005 Oct 14; [Epub ahead of print]
(HSR&T PI: S.C. Kandarian)
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Behnke BJ, Padilla D, Ferreira LF, Delp MD, Musch TI, Poole DC.
Effects of arterial hypotension on microvascular oxygen exchange in contracting skeletal muscle.
J Appl Physiol. 2005 Nov 10; [Epub ahead of print]
(HSR&T PI: M.D. Delp)
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Zayzafoon M, Meyers VE, McDonald JM.
Microgravity: the immune response and bone.
Immunol Rev. 2005 Dec;208:267-80.
(HSR&T PI: J.M.McDonald)
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Riddle RC, Taylor AF, Genetos DC, Donahue HJ.
MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation.
Am J Physiol Cell Physiol. 2005 Nov 2; [Epub ahead of print]
(HSR&T PI: D.C. Genetos, NASA Graduate Student Researcher Program)
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Heiser LM, Colby CL.
Spatial updating in area LIP is independent of saccade direction.
J Neurophysiol. 2005 Nov 16; [Epub ahead of print]
(HSR&T PI: L. Heiser, NASA Graduate Student Researcher Program)
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Lele TP, Pendse J, Kumar S, Salanga M, Karavitis J, Ingber DE.
Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells.
J Cell Physiol. 2005 Nov 15; [Epub ahead of print]
(HSR&T PI: D.E. Ingber)
Note:
From abstract: “These findings demonstrate that the molecular binding kinetics of some, but not all, focal adhesion proteins are sensitive to mechanical force?” Zyxin was found to be sensitive; vinculin was not.
Other papers of interest:
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Voustianiouk A, Kaufmann H, Diedrich A, Raphan T, Biaggioni I, Macdougall H, Ogorodnikov D, Cohen B.
Electrical activation of the human vestibulo-sympathetic reflex.
Exp Brain Res. 2005 Nov 25;:1-11 [Epub ahead of print]
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Popovic ZB, Prasad A, Garcia MJ, Arbab-Zadeh A, Borowski A, Dijk E, Greenberg NL, Levine BD, Thomas JD.
Relationship between diastolic intraventricular pressure gradients, relaxation, and preload: impact of age and fitness.
Am J Physiol Heart Circ Physiol. 2005 Nov 11; [Epub ahead of print]
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Usov AI, Vasiagina TI, Stel’nikova IG.
[Complex morpho-functional characteristic of adrenal medulla and cardiac sino-auricular area in dogs after 30 day hypokinesia]
Morfologiia. 2005;127(2):47-51. Russian.
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Aguila HL, Rowe DW.
Skeletal development, bone remodeling, and hematopoiesis.
Immunol Rev. 2005 Dec;208:7-18.
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Mi LY, Fritton SP, Basu M, Cowin SC.
Analysis of avian bone response to mechanical loading-Part One: Distribution of bone fluid shear stress induced by bending and axial loading.
Biomech Model Mechanobiol. 2005 Oct 25; [Epub ahead of print]
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Xie D, Cheng H, Hamrick M, Zhong Q, Ding KH, Correa D, Williams S, Mulloy A, Bollag W, Bollag RJ, Runner RR, McPherson JC, Insogna K, Isales CM.
Glucose-dependent insulinotropic polypeptide receptor knockout mice have altered bone turnover.
Bone. 2005 Oct 7; [Epub ahead of print]
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Caruso JF, Herron JC, Hernandez DA, Porter A, Schweickert T, Manning TF.
Metabolic responses to the seated calf press exercise performed against inertial resistance.
Aviat Space Environ Med. 2005 Nov;76(11):1019-23.
Note:
The paper describes applicability of this research to the flywheel exercise device said to be scheduled for use on ISS.
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Klosterhalfen S, Kellermann S, Pan F, Stockhorst U, Hall G, Enck P.
Effects of ethnicity and gender on motion sickness susceptibility.
Aviat Space Environ Med. 2005 Nov;76(11):1051-7.
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Bryce LM, Butler WP, Pilmanis AA, King H.
Headache and altitude decompression sickness: joint pain or neurological pain?
Aviat Space Environ Med. 2005 Nov;76(11):1074-8.
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Tafforin C.
Ethological indicators of isolated and confined teams in the perspective of missions to Mars.
Aviat Space Environ Med. 2005 Nov;76(11):1083-7.
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Gandia P, Saivin S, Houin G.
The influence of weightlessness on pharmacokinetics.
Fundam Clin Pharmacol. 2005 Dec;19(6):625-36.
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Maurer C, Mergner T, Peterka RJ.
Multisensory control of human upright stance.
Exp Brain Res. 2005 Nov 24;:1-20 [Epub ahead of print]
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Kasahara S, Akao T, Fukushima J, Kurkin S, Fukushima K.
Further evidence for selective difficulty of upward eye pursuit in juvenile monkeys: effects of optokinetic stimulation, static roll tilt, and active head movements.
Exp Brain Res. 2005 Nov 30;:1-16 [Epub ahead of print]
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Luebke AE, Maroni PD, Guth SM, Lysakowski A.
Alpha-9 nicotinic acetylcholine receptor immunoreactivity in the rodent vestibular labyrinth.
J Comp Neurol. 2005 Nov 21;492(3):323-33.
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Cotrupi S, Ranzani D, Maier JA.
Impact of modeled microgravity on microvascular endothelial cells.
Biochim Biophys Acta. 2005 Nov 2; [Epub ahead of print]
Note:
Used rotating wall vessel bioreactor.
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Carvalho HM, Teel LD, Goping G, O’brien AD.
A three-dimensional tissue culture model for the study of attach and efface lesion formation by enteropathogenic and enterohaemorrhagic Escherichia coli.
Cell Microbiol. 2005 Dec;7(12):1771-81.
Note:
Used rotary cell culture system. This paper can be obtained online without charge.