New Space and Tech

NASA Spaceline Current Awareness List #1,068 29 September 2023 (Space Life Science Research Results)

By Keith Cowing

Status Report

NASA

October 2, 2023

Filed under Astrobiology, Microgravity, NASA, space biology, Space Life Science, Space Medicine, space station

NASA Spaceline Current Awareness List #1,068 29 September 2023 (Space Life Science Research Results) — Astronaut Kate Rubins working with Wet Lab-2, a tool for quantitative gene expression analysis set for further testing this year. Credits: NASA

NASA

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Shawna Byrd, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

Call for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an article that has recently published or will publish in the upcoming weeks within a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your article to the email address mentioned above. Articles received by Wednesday will appear within that week’s list—articles received after Wednesday will appear the following week.

Papers deriving from NASA support:

Olanrewaju GO, Kruse CPS, Wyatt SE.

Functional meta-analysis of the proteomic responses of Arabidopsis seedlings to the spaceflight environment reveals multi-dimensional sources of variability across spaceflight experiments.

Int J Mol Sci. 2023 Sep 22;24(19):14425.

https://doi.org/10.3390/ijms241914425

PI: S.E. Wyatt

Note: ISS results. This article is part of Special Issue “Cellular and Molecular Signaling Meet the Space Environment 2.0” (https://www.mdpi.com/journal/ijms/special_issues/NG6NTA62OE). The Special Issue includes articles from Current Awareness lists #1,034 https://doi.org/10.3390/ijms24021540; #1,048 https://doi.org/10.3390/ijms24087656; #1,058 https://doi.org/10.3390/ijms241311135; #1,064 https://doi.org/10.3390/ijms241612640; and #1,065 https://doi.org/10.3390/ijms241713569 and https://doi.org/10.3390/ijms241713604. This article may be obtained online without charge.

Journal Impact Factor: 5.6

Funding: “This work was partially funded by the National Aeronautics and Space Administration (NASA) Science Mission Directorate grants NASA #80NSSC19K1481 to SEW.”

Vergnes L, Foucaud B, Cepeda C, Espinosa-Jeffrey A.

Metabolomics profile of the secretome of space-flown oligodendrocytes.

Cells. 2023 Sep 11;12(18):2249.

https://doi.org/10.3390/cells12182249

PI: A. Espinosa-Jeffrey

Note: ISS Results. This article belongs to Topical Collection “Oligodendrocyte Physiology and Pathology Function” (https://www.mdpi.com/journal/cells/topical_collections/oligodendrocyte_function) and may be obtained online without charge.

Journal Impact Factor: 6.0

Funding: “NASA Space Biology Grant: NNX15AB43G; the Cell Culture and Imaging Core is supported by the NIH (Grant U54HD08710).”

Ramos-Nascimento A, Grenga L, Haange SB, Himmelmann A, Arndt FS, Ly YT, Miotello G, Pible O, Jehmlich N, Engelmann B, von Bergen M, Mulder E, Frings-Meuthen P, Hellweg CE, Jordan J, Rolle-Kampczyk U, Armengaud J, Moeller R.

Human gut microbiome and metabolite dynamics under simulated microgravity.

Gut Microbes. 2023 Dec;15(2):2259033.

https://pubmed.ncbi.nlm.nih.gov/37749878

Note: Bed rest study (AGBRESA is the Artificial Gravity Bed Rest—European Space Agency). This article may be obtained online without charge.

Journal Impact Factor: 12.2

Funding: “The DLR research team received funding from the following DLR grants: ISS LIFE (Program RF-FuW, Grant#475). The study was funded by the German Aerospace Center, the European Space Agency (contract number 4000113871/15/ NL/PG) and the National Aeronautics and Space Administration (contract number 80JSC018P0078), and performed at the :envihab research facility of the DLR Institute of Aerospace Medicine. A.R.N. was supported by the DLR/ DAAD Research Fellowship [57575486]. These results will be included in the PhD thesis of A. H.”

Rosa-Caldwell ME, Mortreux M, Wadhwa A, Kaiser UB, Sung D-M, Bouxsein ML, Rutkove SB.

Sex differences in muscle health in simulated micro- and partial-gravity environments in rats.

Sports Med Health Sci. 2023 Sep 12. Onine ahead of print.

https://doi.org/10.1016/j.smhs.2023.09.002

PIs: M.E. Rosa-Caldwell, S.B. Rutkove

Note: Hindlimb unloading study.

Journal Impact Factor: Not available for this journal

Funding: “This study was funded by NASA Awards: 80NSSC21K0311 (M.E.R/S.B.R) and 80NSSC19K1598 (S.B.R) as well as NIH Award: R37HD019938 (U.B.K.), and T32GM144273 (A.W.) from the National Institute of General Medical Sciences.”

Waisberg E, Ong J, Zaman N, Paladugu P, Kamran SA, Tavakkoli A, Lee AG.

The spaceflight contrast sensitivity hypothesis and its role to investigate the pathophysiology of spaceflight-associated neuro-ocular syndrome.

Front Ophthalmol. 2023 Sep 5;3:1229748.

https://doi.org/10.3389/fopht.2023.1229748

PI: A. Tavakkoli

Note: This is an opinion article and may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “This work is supported by the National Aeronautics and Space Administration (NASA) and is part of our development of a non-invasive framework for astronaut vision, with the goal of monitoring subtle vision changes that occur during spaceflight.”

Desorgher L, Stabilini A, Rostomyan T, Reggiani D, Hajdas W, Marcinkowski RM, Vozenin M-C, Limoli CL, Yukihara EG, Bailat C.

Dosimetry of the PIM1 pion beam at the Paul Scherrer Institute for Radiobiological Studies of Mice.

Radiat Res. 2023 Sep 13. Online ahead of print.

https://doi.org/10.1667/RADE-23-00029.1

PI: C.L. Limoli

Journal Impact Factor: 3.4

Funding: NASA grant NNX15AI22G.

Ranson TM, Barton ME, McLean RJC.

Influence of central metabolism disruption on Escherichia coli biofilm formation.

Can J Microbiol. 2023 Sep 20. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/37728257

PI: R.J.C. McLean

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.8

Funding: “This study was funded by grants from the National Aeronautics and Space Administration (grant HS5HWWK1AAU5), the US National Science Foundation (grant 2224449) and a Research Enhancement Program grant from Texas State University.”

Bakshi A, Choi WG, Kim SH, Gilroy S.

The vacuolar Ca²⁺

transporter CATION EXCHANGER 2 regulates cytosolic calcium homeostasis, hypoxic signaling, and response to flooding in Arabidopsis thaliana.

New Phytol. 2023 Sep 25. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/37743731

PI: S. Gilroy

Note: This article may be obtained online without charge.

Journal Impact Factor: 9.4

Funding: “We thank Dr. Sarah Swanson, for critical reading of the manuscript and Amanda Miller for invaluable technical assistance. Supported by NSF (NSF IOS1557899, MCB2016177), NASA (NNX14AT25G, 80NSSC19K0126 and 80NSSC21K0577), and USDA Hatch (NEV00389).”

Garcias-Bonet N, Roik A, Tierney B, García FC, Villela HDM, Dungan AM, Quigley KM, Sweet M, Berg G, Gram L, Bourne DG, Ushijima B, Sogin M, Hoj L, Duarte G, Hirt H, Smalla K, Rosado AS, Carvalho S, Thurber RV, Ziegler M, Mason CE, van Oppen MJH, Voolstra CR, Peixoto RS.

Horizon scanning the application of probiotics for wildlife.

Trends Microbiol. Sep 25. Online ahead of print.

https://doi.org/10.1016/j.tim.2023.08.012

PI: C.E. Mason

Note: This article may be obtained online without charge.

Journal Impact Factor: 15.9

Funding: “… C.E.M. and B.T. would also like to thank the WorldQuant Foundation, NASA (80NSSC22K0254), and the National Institutes of Health (R01AI151059, U01DA053941). …”

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Other papers of interest:

Scarsoglio S, Fois M, Ridolfi L.

Increased hemodynamic pulsatility in the cerebral microcirculation during parabolic flight-induced microgravity: A computational investigation.

Acta Astronaut. 2023 Oct;211:344-52.

https://doi.org/10.1016/j.actaastro.2023.06.018

Tong F, Wu C, Wang L, Jing X, Wu S, Sun J, Hu Y, Li J, Wang Y, Li Y.

Can XunTian Tai Chi intervention improve the level of emotional regulation of crew members in the Controlled Ecological Life Support System?

Sports Med Health Sci. 2023 Sep;5(3):245-50.

https://pubmed.ncbi.nlm.nih.gov/37753425

Note: From the abstract: “To explore the appropriate exercise methods and means for astronauts in confined and small isolation conditions, a set of XunTian Tai Chi suitable for the spaceflight workforce was created, with the aim of discovering the practical effects of XunTian Tai Chi and providing a scientific basis for the subsequent development of new astronaut health maintenance techniques with Chinese characteristics.”

Waisberg E, Ong J, Lee AG.

Space radiation and the potential for early cataract development.

Eye (Lond). 2023 Sep 21.

https://pubmed.ncbi.nlm.nih.gov/37735211

Note: This article is a comment.

Wang J, Huang Z.

Multiscale numerical simulations of plasma charging effects for astronaut at the lunar terminator.

IEEE Transactions on Plasma Science. 2023 Jul 31;1-10.

https://doi.org/10.1109/TPS.2023.3295416

Note: From the abstract: “We present four correlated simulation studies concerning plasma charging and its effects over ten orders of magnitude in length scales for astronaut on extravehicular activity (EVA) at the lunar terminator.”

Wiedmann I, Weerts G, Brixius K, Seemüller A, Mittelstädt J, Herssens N, Weber T.

The ESA Parastronaut Feasibility Project: Investigating the need and contents of physical performance tests for an inclusive European Astronaut Corps.

Sports Med. 2023 Sep 25. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/37747665

Note: This article may be obtained online without charge.

Muñoz-Hisado V, Ruiz-Blas F, Sobrado JM, Garcia-Lopez E, Martinez-Alonso E, Alcázar A, Cid C.

Bacterial molecular machinery in the Martian cryosphere conditions.

Front Microbiol. 2023 Jul 26;14.

https://doi.org/10.3389/fmicb.2023.1176582

Note: This article is part of Research Topic “The Impact of the Space Environment on Microbial Growth and Behavior” (https://www.frontiersin.org/research-topics/27130/the-impact-of-the-space-environment-on-microbial-growth-and-behavior#overview). The Research Topic also includes articles from previous Current Awareness Lists #1,009 https://doi.org/10.3389/fmicb.2022.877625, https://doi.org/10.3389/fmicb.2022.893071, and https://doi.org/10.3389/fmicb.2022.909997; #1,041 https://doi.org/10.3389/fmicb.2023.1090740; #1,046 https://doi.org/10.3389/fmicb.2023.1155726; #1,050 https://doi.org/10.3389/fmicb.2023.1150224; and #1,053 https://doi.org/10.3389/fmicb.2023.1150224. This article may be obtained online without charge.