NASA Spaceline Current Awareness List #1,038 24 February 2023 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm.
Please send any correspondence to Shawna Byrd, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.
Call for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an article that has recently published or will publish in the upcoming weeks within a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your article to the email address mentioned above. Articles received by Wednesday will appear within that week’s list—articles received after Wednesday will appear the following week.
Papers deriving from NASA support:
1
Veliz AL, Mamoun L, Hughes L, Vega R, Holmes B, Monteon A, Bray J, Pecaut MJ, Kearns-Jonker M.
Transcriptomic effects on the mouse heart following 30 days on the International Space Station.
Biomolecules. 2023 Feb 15;13(2):371.
https://doi.org/10.3390/biom13020371
PI: M.J. Pecaut
Note: ISS results. This article is part of Special Issue “Effects of Weightlessness on Molecular Changes in Cellular Organisms, Animals and Plants” (https://www.mdpi.com/journal/biomolecules/special_issues/5JR4HV8X19). The Special Issue also includes articles from previous Current Awareness List #1,035 https://doi.org/10.3390/biom13020201 and https://doi.org/10.3390/biom13020189. Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
Journal Impact Factor: 6.064
Funding: “This research was funded by NASA grant number NNX13AN34G (to MP) and by the Dept of Pathology and Human Anatomy at Loma Linda University.”
2
Aguda R, Stelly C, Fonseca L, LeBoeuf S, Massiha S, Chistoserdov A, Holmes WE, Hernandez R, Zappi ME, Revellame ED.
Effect of macronutrient levels on Chlorella vulgaris cultivation for long duration spaceflights and space settlements.
Acta Astronaut. 2023 Feb 22. Online ahead of print.
https://doi.org/10.1016/j.actaastro.2023.02.031
Note: ISS results.
Journal Impact Factor: 2.954
Funding: “This work was supported by the NASA EPSCoR, the Louisiana Board of Regents [Grant No.: 80NSSC18M0062] and Louisiana Space Grant Consortium (LaSPACE) [Award No.: PO-0000139171].”
3
Clément G, Wood S.
Space physiology.
Biaggioni I, Browning K, Fink G, Jordan J, Low PA, Paton JFR, editors.
In: Primer on the Autonomic Nervous System (Fourth Edition). Academic Press, 2023. p. 329-32.
https://doi.org/10.1016/B978-0-323-85492-4.00058-2
Funding: G. Clément and S. Wood are affiliated with NASA Johnson Space Center.
4
Waisberg E, Ong J, Masalkhi M, Zaman N, Kamran SA, Sarker P, Lee AG, Tavakkoli A.
Text-to-image artificial intelligence to aid clinicians in perceiving unique neuro-ophthalmic visual phenomena.
Ir J Med Sci. 2023 Feb 14.
https://pubmed.ncbi.nlm.nih.gov/36787030
PI: A. Tavakkoli
Journal Impact Factor: 2.089
Note: This is a letter to the editor.
Funding: “NASA Grant [80NSSC20K183]: A Non-intrusive Ocular Monitoring Framework to Model Ocular Structure and Functional Changes due to Long-term Spaceflight.”
5
Washio T, Krainski F, Fu Q, Levine BD.
Blood pressure during ambulation: Are noninvasive beat-by-beat finger measures and intermittent brachial measures comparable?
Clin Auton Res. 2023 Feb 17.
https://pubmed.ncbi.nlm.nih.gov/36800050
PI: B.D. Levine
Note: This is a letter to the editor.
Journal Impact Factor: 5.625
Funding: “This study was supported by the National Space Biomedical Research Institute through National Aeronautic and Space Administration NCC 9-58.”
6
Vann W, Zhou T, Zhu Q, Du E.
Enabling automated facility maintenance from articulated robot collision-free designs.
Adv Eng Inform. 2023 Jan 23;55:101820.
https://doi.org/10.1016/j.aei.2022.101820
PI: E. Du
Journal Impact Factor: 7.862
Funding: “This material is supported by the National Aeronautics and Space Administration (NASA) under grant 80NSSC21K0845.”
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Other papers of interest:
1
Blottner D, Moriggi M, Trautmann G, Hastermann M, Capitanio D, Torretta E, Block K, Rittweger J, Limper U, Gelfi C, Salanova M.
Space omics and tissue response in astronaut skeletal muscle after short and long duration missions.
Int J Mol Sci. 2023 Feb 17;24(4):4095.
https://doi.org/10.3390/ijms24044095
Note: ISS results. This article is part of Special Issue “Novel Molecular Approaches to Skeletal Muscle Disease and Disuse 2.0” (https://www.mdpi.com/journal/ijms/special_issues/Approaches_Skeletal_Muscle2). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
2
Theotokis P, Manthou ME, Deftereou T-E, Miliaras D, Meditskou S.
Addressing spaceflight biology through the lens of a histologist-embryologist.
Life. 2023 Feb 20;13(2):588. Review.
https://doi.org/10.3390/life13020588
Note: This article is part of Special Issue “The Space Environment on Human Health and Disease” (https://www.mdpi.com/journal/life/special_issues/space_microbiome). The Special Issue also includes articles from previous Current Awareness Lists #997 https://doi.org/10.3390/life12040495; #1,011 https://doi.org/10.3390/life12071060 and https://doi.org/10.3390/life12081163; #1,015 https://doi.org/10.3390/life12091301; and #1,026 https://doi.org/10.3390/life12111865. Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
3
Fiedler P, Haueisen J, Alvarez AMC, Cheron G, Cuesta P, Maestú F, Funke M.
Noise characteristics in spaceflight multichannel EEG.
PLoS One. 2023 Feb 17;18(2):e0280822.
https://pubmed.ncbi.nlm.nih.gov/36800392
Note: From the abstract: “The cognitive performance of the crew has a major impact on mission safety and success in spaceflight. Monitoring of cognitive performance during long-duration spaceflight therefore is of paramount importance and can be performed using compact state-of-the-art mobile electroencephalography (EEG). However, signal quality of EEG may be compromised due to the vicinity to various electronic devices and constant movements. We compare noise characteristics between in-flight extraterrestrial microgravity and ground-level terrestrial electroencephalography recordings. EEG data recordings from either aboard International Space Station (ISS) or on Earth’s surface, utilizing three EEG amplifiers and two electrode types, were compared.” This article may be obtained online without charge.
4
Zhao L, Zhang G, Tang A, Huang B, Mi D.
Microgravity alters the expressions of DNA repair genes and their regulatory miRNAs in space-flown Caenorhabditis elegans.
Life Sci Space Res. 2023 May;37:25-38.
https://doi.org/10.1016/j.lssr.2023.02.002
Note: From the abstract: “In this study, we collected all existing datasets including transcriptional and miRNA microarrays from space-flown C. elegans. By principal component analysis (PCA) and differential expression analysis, we investigated the expression patterns of DNA repair genes annotated in different DNA repair pathways and their regulatory miRNAs. By miRNA-mRNA integrated analysis, we determined the regulatory network of differentially expressed DNA repair genes and miRNAs to identify the key miRNAs that potentially regulated the expressions of DNA repair genes. Based on these results, we made efforts to reveal the possible effects and regulatory mechanisms of microgravity on various DNA repair pathways under microgravity.”
5
Bi D, Liu C, Dai Z, Li Z, Li Y, Li B, Li D, Wang L, Qu L, Li Y, Ta D.
Human bone loss assessed by high-resolution peripheral quantitative computed tomography and ultrasonic transmission techniques.
Microgravity Sci Technol. 2023 Feb 21;35:12.
https://doi.org/10.1007/s12217-023-10037-0
Note: Head-down tilt bedrest study. From the article: “This study aims to investigate bone loss and recovery during simulated microgravity by high-resolution peripheral quantitative computed tomography (HR-pQCT) and ultrasonic transmission techniques, and to compare the efficacy of state-of-the-art ultrasonic transmission and backscatter techniques in assessing bone loss.”
6
De Martino E, Green DA, Ciampi de Andrade D, Weber T, Herssens N.
Human movement in simulated hypogravity-Bridging the gap between space research and terrestrial rehabilitation.
Front Neurol. 2023 Feb 6;14:1062349.
https://pubmed.ncbi.nlm.nih.gov/36815001
Note: This article is part of Research Topic “Human Movement in Simulated Hypogravity–Bridging the Gap between Space Research and Terrestrial Rehabilitation” (https://www.frontiersin.org/research-topics/37230/human-movement-in-simuated-hypogravity—bridging-the-gap-between-space-research-and-terrestrial-rehabilitation#overview). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
7
Liu C-J, Yang X, Mao Y, Zhang X-X, Wu X-T, Wang S-H, Fan Y-B, Sun L-W.
The alteration of advanced glycation end products and its potential role on bone loss under microgravity.
Acta Astronaut. 2023 May;206:114-22.
https://doi.org/10.1016/j.actaastro.2023.02.019
Note: Hindlimb unloading study.
8
Saveko A, Bekreneva M, Ponomarev I, Zelenskaya I, Riabova A, Shigueva T, Kitov V, Abu Sheli N, Nosikova I, Rukavishnikov I, Sayenko D, Tomilovskaya E.
Impact of different ground-based microgravity models on human sensorimotor system.
Front Physiol. 2023 Feb 15;14:1085545.
https://doi.org/10.3389/fphys.2023.1085545
Note: This article is part of Research Topic “Women in Space Physiology 2022” (https://www.frontiersin.org/research-topics/34966/women-in-space-physiology-2022#overview). The Research Topic also includes an article from previous Current Awareness List #1,021 https://doi.org/10.3389/fphys.2022.1039924. Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
9
Wu B, Gao X, Qin B, Baldoni M, Zhou L, Qian Z, Zhu Q.
Effect of microgravity on mechanical loadings in lumbar spine at various postures: A numerical study.
npj Microgravity. 2023 Feb 15;9:16.
https://pubmed.ncbi.nlm.nih.gov/36792893
Note: From the abstract: “The aim of this study was to quantitatively analyze the mechanical change of spinal segments (disc, muscle, and ligament) at various postures under microgravity using a full-body musculoskeletal modeling approach. Specifically, in the lumbar spine, the vertebra were modeled as rigid bodies, the intervertebral discs were modeled as 6-degree-of-freedom joints with linear force-deformation relationships, the disc swelling pressure was deformation dependent, the ligaments were modeled as piecewise linear elastic materials, the muscle strength was dependent on its functional cross-sectional area. The neutral posture and the ‘fetal tuck’ posture in microgravity (short as ‘Neutral 0G’ and ‘Fetal Tuck 0G,’ in our simulation, the G constant was set to 0 for simulating microgravity), and for comparison, the relaxed standing posture in 1G and 0G gravity (short as ‘Neutral 1G’ and ‘Standing 0G’) were simulated.” This article may be obtained online without charge.
10
Lee H, Lim D, Kang Y.
Recurrent decompression illness even after the closure of patent foramen ovale in a diver.
JACC: Case Reports. 2023 Jan 4;5:101687.
https://doi.org/10.1016/j.jaccas.2022.101687
Note: From the abstract: “Patent foramen ovale (PFO) is a risk factor for the development of decompression illness (DCI) and a therapeutic target for preventing the recurrence of DCI because nitrogen bubbles generated during diving can be paradoxically embolized through the PFO. Here, we report the case of a diver who experienced recurrent DCI even after a successful PFO closure.”
11
Takahashi I, Matsuzaki T, Kuroki H, Hoso M.
Treadmill exercise suppresses histological progression of disuse atrophy in articular cartilage in rat knee joints during hindlimb unloading.
Cartilage. 2023 Feb 17:19476035231154510. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/36802945
Note: Hindlimb unloading study. From the abstract: “Twenty male rats were divided into 4 experimental groups, including the control, hindlimb unloading, physiological loading, and treadmill walking groups. Histological changes in the articular cartilage and bone of the tibia were histomorphometrically and immunohistochemically evaluated 4 weeks after the intervention.”
12
Bao XC, Wang N, Xu J, Ma J, Fang YQ.
Effects of different simulated submarine escape depths by free ascent in animal models.
Front Physiol. 2023 Jan 27;14:1107782.
https://pubmed.ncbi.nlm.nih.gov/36776974
Note: This article is part of Research Topic “Physiology in extreme conditions: Adaptations and unexpected reactions, Volume II” (https://www.frontiersin.org/research-topics/29492/physiology-in-extreme-conditions-adaptations-and-unexpected-reactions-volume-ii#articles). The Research Topic also includes articles from previous Current Awareness List #1,000 https://doi.org/10.3389/fphys.2022.893025 and https://doi.org/10.3389/fphys.2022.882944. This article may be obtained online without charge.
