NASA Spaceline Current Awareness List #1,034 27 January 2023 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm.
Please send any correspondence to Shawna Byrd, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.
Call for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an article that has recently published or will publish in the upcoming weeks within a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your article to the email address mentioned above. Articles received by Wednesday will appear within that week’s list—articles received after Wednesday will appear the following week.
Papers deriving from NASA support:
1
Anupom T, Vanapalli SA.
A compact imaging platform for conducting C. elegans phenotypic assays on Earth and in spaceflight.
Life (Basel). 2023 Jan 10;13(1):200.
https://pubmed.ncbi.nlm.nih.gov/36676149
PI: S.A. Vanapalli
Note: From the abstract: “In this study, we report a 3D printed compact imaging platform (CIP) that is integrated with a smart-device camera for the whole-organism phenotyping of C. elegans.” This article is part of Special Issue “Advances in Space Biology” (https://www.mdpi.com/journal/life/special_issues/_space_biology). The Special Issue also includes articles from previous Current Awareness Lists #1,002 https://doi.org/10.3390/life12050610, #1,015 https://doi.org/10.3390/life12081176, #1,019 https://doi.org/10.3390/life12101498, and #1,025 https://doi.org/10.3390/life12111838. Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
Journal Impact Factor: 3.253
Funding: “We thank Hunter Edwards for suggesting the strains used for the behavioral studies and for valuable discussions. We are also grateful for Dhaval Patel and Mizanur Rahman for the critical reading of the manuscript, statistical analysis and feedback provided. The strains used in this study were acquired from Caenorhabditis Genetics Center (CGC), funded by the NIH Office of Research Infrastructure Programs (P40 OD010440). This work was partially funded by NASA (Grant No. NNX15AL16G).”
2
Chander AM, Teixeira MM, Singh NK, Williams MP, Simpson AC, Damle N, Parker CW, Stajich JE, Mason CE, Torok T, Venkateswaran K.
Description and genome characterization of three novel fungal strains isolated from Mars 2020 mission-associated spacecraft assembly facility surfaces-recommendations for two new genera and one species.
J Fungi (Basel). 2022 Dec 23;9(1):31.
https://pubmed.ncbi.nlm.nih.gov/36675851
Note: This article is part of Special Issue “Genomics Analysis of Fungi” (https://www.mdpi.com/journal/jof/special_issues/fungi_genomics). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
Journal Impact Factor: 5.724
Funding: “The research described in this manuscript was funded by the NNH18ZDA001N-PPR award 18-PPR18-0011 to KV.”
3
Macaulay TR, Wood SJ, Bollinger A, Schubert MC, Shelhamer M, Bishop MO, Reschke MF, Clément G.
Comparison of asymmetry between perceptual, ocular, and postural vestibular screening tests.
Brain Sci. 2023 Jan 23;13(2):189.
https://doi.org/10.3390/brainsci13020189
PIs: M.C. Schubert, M. Shelhamer, M.F. Reschke, G. Clément
Note: This article is part of Section “Sensory and Motor Neuroscience” (https://www.mdpi.com/journal/brainsci/sections/Sensory_Motor_Neuroscience_) and may be obtained online without charge.
Journal Impact Factor: 3.333
Funding: “This research was funded by the NASA Human Research Program (HRP) Human Health and Countermeasures Element 80JSC017N0001 Complement of Integrated Protocols for Human Ex-ploration Research (T.R.M., S.J.W., A.B., M.O.B., M.F.R., G.R.C.), and NASA HRP 80NSSC19K0487, NASA HRP 80NSSC20K1498, and the Translational Research Institute through NASA NNX16AO69A (M.C.S. and M.S.).
Note about funding: Found Shubert, Reschke, and Clement under 80JSC017N0001. Shelhamer is 80NSSC19K0487, NASA HRP 80NSSC20K1498 pi. Macaulay and Wood are listed under Clement as CO-Is.”
4
Lalwala M, Koya B, Devane K, Gayzik FS, Weaver AA.
Modular incorporation of deformable spine and 3D neck musculature into a simplified human body finite element model.
Comput Methods Biomech Biomed Engin. 2023 Jan 19:1-11.
https://pubmed.ncbi.nlm.nih.gov/36657616
PI: A.A. Weaver
Journal Impact Factor: 1.669
Funding: “This study was supported by NASA [grant number NNX16AP89G]. Dr. Weaver is supported by a Career Development Award from the NIH [grant number K25 AG058804].”
5
Su SH, Moen A, Groskopf RM, Baldwin KL, Vesperman B, Masson PH.
Low-speed clinorotation of Brachypodium distachyon and Arabidopsis thaliana seedlings triggers root tip curvatures that are reminiscent of gravitropism.
Int J Mol Sci. 2023 Jan 12;24(2):1540.
https://pubmed.ncbi.nlm.nih.gov/36675054
PI: P.H. Masson
Note: This article is part of Special Issue “Cellular and Molecular Signaling Meet the Space Environment 2.0” (https://www.mdpi.com/journal/ijms/special_issues/NG6NTA62OE). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
Journal Impact Factor: 6.208
Funding: “This work was supported by grants from the National Aeronautics and Space Administration (grant number 80NSSC18K1481) and from the National Science Foundation (grant number 1951182-IOS).”
6
Griffith JL, Cluff K, Downes GM, Eckerman B, Bhandari S, Loflin BE, Becker R, Alruwaili F, Mohammed N.
Wearable sensing system for noninvasive monitoring of intracranial biofluid shifts in aerospace applications.
Sensors (Basel). 2023 Jan 14;23(2):985.
https://pubmed.ncbi.nlm.nih.gov/36679781
Note: From the abstract: “The alteration of the hydrostatic pressure gradient in the human body has been associated with changes in human physiology, including abnormal blood flow, syncope, and visual impairment. The focus of this study was to evaluate changes in the resonant frequency of a wearable electromagnetic resonant skin patch sensor during simulated physiological changes observed in aerospace applications.” This article may be obtained online without charge.
Journal Impact Factor: 3.847
Funding: “This work was supported in part by a grant from the National Aeronautics and Space Administration (NASA) (Grant number: NNX16AQ99A) and National Science Foundation Graduate Research Fellowship (#1849525). This material is also the result of work supported in part with the resources and the use of facilities at Wichita State University.”
7
Westover C, Rahmatulloev S, Danko D, Afshin EE, O’Hara NB, Ounit R, Bezdan D, Mason CE.
Ozone disinfection for elimination of bacteria and degradation of SARS-CoV2 RNA for medical environments.
Genes (Basel). 2022 Dec 28;14(1):85.
https://pubmed.ncbi.nlm.nih.gov/36672826
PI: C.E. Mason
Note: This article is part of Special Issue “Microbiome Analysis Techniques and Discovery” (https://www.mdpi.com/journal/genes/special_issues/microbiome_a_techniques). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
Journal Impact Factor: 4.69
Funding: “We would like to thank funding from the Irma T. Hirschl and Monique Weill-Caulier Charitable Trusts, Bert L and N Kuggie Vallee Foundation, the WorldQuant Foundation, the Pershing Square Sohn Cancer Research Alliance as well as NASA (NNX14AH50G, NNX17AB26G), the National Institutes of Health (R25EB020393, R01NS076465, R01AI125416, R01ES021006, 1R21AI129851, 1R01MH117406), the Bill and Melinda Gates Foundation (OPP1151054).”
___________________________________________________
Other papers of interest:
1
Navarro Morales DC, Kuldavletova O, Quarck G, Denise P, Clément G.
Time perception in astronauts onboard the International Space Station.
npj Microgravity. 2023 Jan 19;9:6.
https://pubmed.ncbi.nlm.nih.gov/36658133
Note: ISS results. This article may be obtained online without charge.
2
Gupta U, Baig S, Majid A, Bell SM.
The neurology of spaceflight; How does spaceflight effect the human nervous system?
Life Sci Space Res. 2023 Feb;36:105-15. Review.
https://doi.org/10.1016/j.lssr.2022.09.003
Note: From the abstract: “This review aims to describe the neurological effects of spaceflight and to assess countermeasures such as pre-flight prophylaxis, training, and possible therapeutics to reduce long-term effects.”
3
Larina IM, Buravkova LB, Grigoriev AI.
Oxygen-dependent adaptation processes in a human organism in normal living conditions and during spaceflight.
Hum Physiol. 2023 Jan;48(7):838-50. Review.
https://doi.org/10.1134/S0362119722070118
Note: From the abstract: “This review examines various parties of oxygen-dependent human adaptation to microgravity belonging to different levels of the integral system organization.”
4
Rasheed M, Wang H, Wang C, Sun J, Chen Z, Deng Y.
Opposing manner of miR-455-3p against NR2B-PSD-95-nNOS complex in the cortex and hippocampus of depressive rats under simulated complex space environment.
J Neurochem. 2023 Jan 17. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/36648213
Note: From the abstract: “Using a simulated space environment complex model (SCSE) for 21 days, we induced depressive behavior in rats to analyze miR-455-3p expression and NR2B-PSD-95-nNOS complex in the cortex and hippocampus of the SCSE depressed rats through qRT-PCR and western blot analysis.”
5
Aissiou AK, Jha S, Dhunnoo K, Ma Z, Li DX, Ravin R, Kunze M, Wong K, Adesida AB.
Transcriptomic response of bioengineered human cartilage to parabolic flight microgravity is sex-dependent.
npj Microgravity. 2023 Jan 19;9:5.
https://pubmed.ncbi.nlm.nih.gov/36658138
Note: From the introduction: “In this study, we hypothesize that the transcriptome of tissue-engineered human cartilage will be perturbed by short-term microgravity via parabolic flight maneuvers in a sex-dependent manner.” This article may be obtained online without charge.
6
Calcagno G, Jeandel J, Frippiat JP, Kaminski S.Simulated microgravity disrupts nuclear factor κB signaling and impairs murine dendritic cell phenotype and function.
Int J Mol Sci. 2023 Jan 15;24(2):1720.
https://pubmed.ncbi.nlm.nih.gov/36675236
Note: A random positioning machine was used in this study. This article may be obtained online without charge.
7
Cheng K, Feng Xa, Yang C, Ma C, Niu S, Jia L, Yang X, Liang J, Bo Y, Geng K, Li Q, Zhang H, Lei X, Zhang Y.
Simulated microgravity reduces quality of ovarian follicles and oocytes by disrupting communications of follicle cells.
npj Microgravity. 2023 Jan 23;9(1):7.
https://doi.org/10.1038/s41526-023-00248-5
Note: From the introduction: “To simulate microgravity, a rotating bioreactor, rotating cell culture system (RCCS) that can maintain cells in a controlled rotation environment to mimic the impacts of microgravity, was devised.” This article may be obtained online without charge.
8
Ranade AV, Khan AA, Gul MT, Jose J, Ramachandran G, Qaisar R, Karim A, Ahmad F, Abdel-Rahman WM.
Pharmacological inhibition of endoplasmic reticulum stress mitigates testicular pathology in a mouse model of simulated microgravity.
Acta Astronaut. 2023 Mar;204:466-76.
https://doi.org/10.1016/j.actaastro.2023.01.011
Note: Hindlimb unloading study. This article may be obtained online without charge.
9
Sanesi L, Storlino G, Dicarlo M, Oranger A, Zerlotin R, Pignataro P, Suriano C, Guida G, Grano M, Colaianni G, Colucci SC.
Time-dependent unloading effects on muscle and bone and involvement of FNDC5/irisin axis.
npj Microgravity. 2023 Jan 19;9:4.
https://doi.org/10.1038/s41526-023-00251-w
Note: Hindlimb unloading study. This article may be obtained online without charge.
10
Ponomarev SA, Shulguina SM, Kalinin SA, Antropova EN, Rykova MP, Orlova KD, Kutko OV, Shmarov VA, Vlasova DD, Sadova AA.
State of the human innate immunity cell component during 120-day isolation in a pressurized module.
Hum Physiol. 2023 Jan;48:827-32.
https://doi.org/10.1134/S036211972207009X
11
You J, Chen X, Zhou M, Ma H, Liu Q, Huang C.
Hyperbaric oxygen preconditioning for prevention of acute high-altitude diseases: Fact or fiction?
Front Physiol. 2023 Jan 25;14:1019103.
https://doi.org/10.3389/fphys.2023.1019103
Note: This article is part of Research Topic “Neurological, Neurophysiological, Psychological and Psychiatric Effects of High Altitude and Hypoxia” (https://www.frontiersin.org/research-topics/24670/neurological-neurophysiological-psychological-and-psychiatric-effects-of-high-altitude-and-hypoxia#overview). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
12
Ibrahim EH, Sosa A, Brown SA, An D, Klawikowski S, Baker J, Bergom C.
Myocardial contractility pattern characterization in radiation-induced cardiotoxicity using magnetic resonance imaging: A pilot study with ContractiX.
Tomography. 2022 Dec 22;9(1):36-49.
https://pubmed.ncbi.nlm.nih.gov/36648991
Note: This article is part of Topic “Cardiac Imaging: State of the Art” (https://www.mdpi.com/topics/cardic_imaging) and may be obtained online without charge.
13Antal I, Szőke G, Szendrői M, Szalay K, Perlaky T, Kiss J, Skaliczki G.
Functional outcome and quality of life following resection of the proximal humerus performed for musculoskeletal tumors and reconstruction done by four different methods.
Musculoskelet Surg. 2023 Jan 17.
https://pubmed.ncbi.nlm.nih.gov/36648636
Note: This article may be obtained online without charge.
14
Faricier R, Haeberlé O, Lemire M.
Short-term cold-water immersion does not alter neuromuscular fatigue development during high-intensity intermittent exercise.
Front Physiol. 2023 Jan 24;13:1061866.
https://doi.org/10.3389/fphys.2022.1061866
Note: This article is part of Research Topic “Acute and Long-term health issues of occupational exposure to Heat and High physical loads” (https://www.frontiersin.org/research-topics/38624/acute-and-long-term-health-issues-of-occupational-exposure-to-heat-and-high-physical-loads#overview). This article may be obtained online without charge.
15
Katuntsev VP, Sukhostavtseva TV, Baranov MV, Kotov AN, Puchkova AA, Tarasenkov GG, Nosovsky AM.
Effect of 14-day head-up bedrest on orthostatic tolerance in humans.
Hum Physiol. 2023 Jan 23;48:809-15.
Note: Head-up bedrest study.
16
Kim H, Kim J, Choi G.
Epidermal phyB requires RRC1 to promote light responses by activating the circadian rhythm.
New Phytol. 2023 Jan 18. Online ahead of print.
17
Arana-De Las Casas NI, De la Riva-Rodríguez J, Maldonado-Macías AA, Sáenz-Zamarrón D.
Cognitive analyses for interface design using dual N-Back tasks for mental workload (MWL) evaluation.
Int J Environ Res Public Health. 2023 Jan 9;20(2):1184.
Note: NASA Task Load Index was used in this study. This article may be obtained online without charge.
18
Kumar L, Gaikwad KK.
Advanced food packaging systems for space exploration missions.
Life Sci Space Res. 2023 Jan 23. Review. Online ahead of print.
Note: From the abstract: “Since the advent of space exploration missions, various space agencies have been working to improve the quality of food and nutrition for crew members. Food processing, preservation, and packaging have evolved with the advancement of technology. Most of the food available on earth can be consumed in space by changing its form. Shelf life and food acceptability can be enhanced by using suitable packaging materials. Here we review space food, which has been categorized into bite-size food, rehydratable food, thermostabilized food, intermediate moisture food, and irradiated food.”
