NASA Spaceline Current Awareness List #954 18 June 2021 (Space Life Science Research Results)

Papers deriving from NASA support:

 

1

McGregor HR, Lee JK, Mulder ER, De Dios YE, Beltran NE, Kofman IS, Bloomberg JJ, Mulavara AP, Smith SM, Zwart SR, Seidler RD.

Hum Brain Mapp. 2021 Jun 9. Online ahead of print.

PI: R. D. Seidler

Note: Head-down tilt bed rest study. This article may be obtained online without charge.

Journal Impact Factor: 4.421

Funding: “NASA grant #80NSSC17K0021. HRM was supported by a NSERC postdoctoral fellowship and a NASA Human Research Program augmentation grant.”

2

Diaz-Artiles A, Karmali F.

Neuroscience. 2021 Jun 2;S0306-4522(21)00275-X. Review. Online ahead of print.

PI: A. Diaz-Artiles

Note: From the abstract: “This review has three objectives: (1) to show the importance of studying vestibular precision, and specifically that studying accuracy without studying precision ignores fundamental aspects of the vestibular system; (2) to synthesize key hypotheses about precision in vestibular perception, the vestibulo-ocular reflex, posture, and neurons; and (3) to show that groups of studies that are thoughts to be distinct (e.g., perceptual thresholds, subjective visual vertical variability, neuronal variability) are actually ‘two sides of the same coin’ – because the methods used allow results to be related to the standard deviation of a Gaussian distribution describing the underlying neural noise.”

Journal Impact Factor: 3.056

Funding: “This research was supported by NIH/NIDCD R03-DC013635 and R01-DC018287 (FK) and the NASA grant 80NSSC20K1499 (AD-A).”

3

Haveman NJ, Khodadad CLM, Dixit AR, Louyakis AS, Massa GD, Venkateswaran K, Foster JS.

npj Microgravity. 2021 Jun 17;7(1):22.

PIs: K. Venkateswaran, N. J. Haveman, NASA Postdoctoral Program Fellowship

Note: From the abstract: “…we developed a methodology to investigate the transcriptional activities of the microbiome of red romaine lettuce, a key salad crop that was grown under International Space Station (ISS)-like conditions.” GeneLab: The raw and processed MinION Oxford Nanopore-sequencing data reported in this study have been deposited with NCBI at Gene Expression Omnibus (GEO) repository (GSE152914) and with NASA’s GeneLab (GLDS-307). GeneLab is available at: https://genelab.nasa.gov. This article may be obtained online without charge.

Journal Impact Factor: 3.380

Funding: “This work was supported in part by NASA through the University of Central Florida’s NASA Florida Space Consortium and Space Florida (NX15AI10H) awarded to J.S.F.  N.J.H. was supported by a NASA Space Biology Postdoctoral Fellowship (80NSSC19K0520). Part of the research was performed at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with NASA. This research was also in part funded by a 2012 Space Biology NNH12ZTT001N grant number 19-12829-26 under Task Order NNN13D111T award to K.V.”

 

4

Kusuma P, Bugbee B.

Front Plant Sci. 2021 May 24;12:596943.

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.591

Funding: “This work was supported by the Utah Agricultural Experiment Station, Utah State University (journal paper number 9381), the USDA-NIFA-SCRI (Grant Number 2018-51181-28365) (LAMP Project) NASA-CUBES (Grant Number NNX17AJ31G).”

 

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Other papers of interest:

 

1

Comfort P, McMahon JJ, Jones PA, Cuthbert M, Kendall K, Lake JP, Haff GG.

Sports Med. 2021 Jun 11. Systematic review. Online ahead of print.

Note: From the abstract: “A literature search was conducted using PubMed, Ovid and Scopus databases. 5541 studies were identified prior to the removal of duplicates and the application of the following inclusion criteria: (1) group means and standard deviations for pre- and post-spaceflight for measures of strength, muscle mass or bone density were reported (or provided by the corresponding author when requested via e-mail), (2) exercise-based countermeasures were included, (3) the population of the studies were human, (4) muscle function was assessed and (5) spaceflight rather than simulated spaceflight was used. The methodological quality of the included studies was evaluated using a modified Physiotherapy Evidence Database (PEDro) scale for quality, with publication bias assessed using a failsafe N (Rosenthal method), and consistency of studies analyzed using I² as a test of heterogeneity. Secondary analysis of studies included Hedges’ g effect sizes, and between-study differences were estimated using a random-effects model.” This article may be obtained online without charge.

2

Wakayama S, Ito D, Kamada Y, Shimazu T, Suzuki T, Nagamatsu A, Araki R, Ishikawa T, Kamimura S, Hirose N, Kazama K, Yang L, Inoue R, Kikuchi Y, Hayashi E, Emura R, Watanabe R, Nagatomo H, Suzuki H, Yamamori T, Tada MN, Osada I, Umehara M, Sano H, Kasahara H, Higashibata A, Yano S, Abe M, Kishigami S, Kohda T, Ooga M, Wakayama T.

Sci Adv. 2021 Jun 11;7(24):eabg5554.

Note: ISS results. From the abstract: “Here, we developed a method to evaluate the biological effect of space radiation and examined the reproductive potential of mouse freeze-dried spermatozoa stored on the International Space Station (ISS) for the longest period in biological research.” This article may be obtained online without charge.

 

3

Yusupova AK, Shved DM, Gushin VI, Chekalina AI, Supolkina NS.

Aviakosm Ekolog Med. 2021;55(2):29-34. Russian.

Note: ISS results. From the abstract: “The Content space experiment used content analysis to examine the features of the speech communication of Russian segment cosmonauts of the International Space Station with the mission control center (CMC).”

 

4

Karpova OI, Rozanov IA, Shved DM, Gushin VI, Karapetyan AS, Potapova KV.

Aviakosm Ekolog Med. 2021;55(2):5-14. Russian.

Note: From the abstract: “The paper gives a retrospect of the psychological support to space crews and highlights its basic goals and methods.”

5

Aviakosm Ekolog Med. 2021;55(2):63-8. Russian.

Note: From the abstract: “Hemodynamics was studied in…8 male subjects exposed to an experimental hypomagnetic environment (HME).”

 

6

Aviakosm Ekolog Med. 2021;55(2):98-101. Russian.

Note: A short-arm centrifuge was used in this study.

 

7

Koloteva MI, Glebova TM, Salnikov AV.

Aviakosm Ekolog Med. 2021;55(2):56-62. Russian.

Note: A short-arm centrifuge was used in this study.

 

8

Aviakosm Ekolog Med. 2021;55(2):48-55. Russian.

Note: Sirius 18/19 isolation and confinement analog mission results. From the abstract: “In the SIRIUS-18/19 project, psychological, neurohormonal and metabolic adaptation to 120-day isolation was studied with participation of 3 male and 3 female subjects between the ages of 28 to 44 years. Mood assessments and biochemical investigations attested to a moderate stress.”

 

9

Aviakosm Ekolog Med. 2021;55(2):35-42. Russian.

Note: Sirius 18/19 isolation and confinement analog mission results. From the abstract: “Innate immunity was investigated in six 28 to 44 year old volunteers for a 120-day isolation in a controlled environment.”

 

10

Bubeev YA, Usov VM, Kryuchkov BI, Altunin АА, Dolgov PP, Mikhaylyuk MV.

Aviakosm Ekolog Med. 2021;55(2):15-28. Russian.

Note: From the abstract: “Analysis of realistic prototypes of a propulsive survival backpack (PSB) and current human-PSB models gave impetus to the development of original tools for designing the scenery and PSB application scenarios with consideration of the VR and 3D experiences in isolation studies and operators’ training. Specifically, the authors created several VR/AR scenarios of emergency egress for participants in isolation studies.”

 

11

García-Aznar JM, Nasello G, Hervas-Raluy S, Pérez M, Gómez-Benito MJ.

Bone. 2021 Jun 9;116032. Review. Online ahead of print.

Note: This article may be obtained online without charge.

 

12

Perier-Metz C, Duda GN, Checa S.

Biomech Model Mechanobiol. 2021 Jun 7. Online ahead of print.

Note: This article may be obtained online without charge.

13

Santos L, Ugun-Klusek A, Coveney C, Boocock DJ.

npj Regen Med. 2021 Jun 7;6(1):32.

Note: This article may be obtained online without charge.

 

14

Killer K, Le O, Beauséjour C.

Radiat Res. 2021 Jun 9. Online ahead of print.

15

Maliszewska-Olejniczak K, Kaniowski D, Araszkiewicz M, Tymińska K, Korgul A.

Front Oncol. 2021 May 19;11:676575. Review.

Note: This article may be obtained online without charge.

 

16

Yu D, Zhang S, Mo W, Jiang Z, Wang M, An L, Wang Y, Liu Y, Jiang S, Wu A, Cao J, Zhang S.

Radiat Res. 2021 Jun 9. Online ahead of print.

17

Shanahan E, Ryan S, Leahy A, Sheehy T, Costelloe A, Roy A, Galvin R, Peters C, Lyons D, O’Connor M.

Exp Gerontol. 2021 Jun 5;111430. Online ahead of print.

Note: Head-up tilt testing was used in this study.

 

18

Aviakosm Ekolog Med. 2021;55(2):43-7 Russian.

Note: Dry immersion was used in this study.

19

Fioranelli M, Sepehri A, Flavin D, Roccia MG, Beesham A.

Biochem Biophys Rep. 2021 May 19;26:101011.

Note: This article may be obtained online without charge.

20

Shutov DV, Arzamasov KM, Drozdov DV, Demkina AE, Drogovoz VA, Vladzimirsky AV, Morozov SP.

Aviakosm Ekolog Med. 2021;55(2):84-9. Russian.