NASA Spaceline Current Awareness List #950 21 May 2021 (Space Life Science Research Results)

Papers deriving from NASA support:

 

1

Macaulay TR, Peters BT, Wood SJ, Clément GR, Oddsson L, Bloomberg JJ.

Front Syst Neurosci. 2021 Apr 27;15:658985. Review.

PI: J.J. Bloomberg

Note: From the introduction: “The overall purpose of this review is to support the conception and development of countermeasures that address the issue of balance impairments after long-duration spaceflight and are compatible with exploration spaceflight conditions. Rather than describe in detail each of the potential countermeasures that have been proposed, here we elucidate the recent findings that drive current directions.” This article may be obtained online without charge.

Journal Impact Factor: 3.293

Funding: “This work was supported by the Human Health and Countermeasures Element of the NASA Human Research Program.”

 

2

Penchev R, Scheuring RA, Soto AT, Miletich DM, Kerstman E, Cohen SP.

Anesthesiology. 2021 May 12. Online ahead of print.

Note: From the abstract: “In this article, the authors discuss epidemiology, pathophysiology, prevention, treatment, and future research.” From the website: “Anesthesiology‘s articles are made freely accessible to all readers on www.anesthesiology.org, for personal use only, 6 months from the cover date of the issue.”

Journal Impact Factor: 7.067

Funding: E. Kerstman is affiliated with NASA Johnson Space Center.

3

Birdsall HH, Hammond TG.

J Toxicol. 2021 Apr 21;2021:6643324. Review.

PI: T.G. Hammond

Note: From the abstract: “This review codifies the techniques used to reintroduce shear stress, the cell lines utilized, and the biological outcomes reported. Further, we propose a set of interventions to enhance future cell biology understanding of nephrotoxicity using cell culture models.” This article may be obtained online without charge.

Journal Impact Factor: Not applicable to this publication

Funding: “This material is the result of work supported with resources and the use of facilities at the Durham Veterans Affairs Health Care System and Duke University School of Medicine. This study was also supported by the NASA grant to the Institute for Medical Research (80NSSC19K0706).”

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Other papers of interest:

 

1

Costa F, Ambesi-Impiombato FS, Beccari T, Conte C, Cataldi S, Curcio F, Albi E.

Front Bioeng Biotechnol. 2021 Apr 21;9:666683. Review.

Note: ISS results. From the abstract: “This review aims to highlight recent studies describing damages of human body induced by the space environment for microgravity, and radiation. All novel conditions, to ally unknown to the Darwinian selection strategies on Earth, to which we should add the psychological stress that astronauts suffer due to the inevitable forced cohabitation in claustrophobic environments, the deprivation from their affections and the need to adapt to a new lifestyle with molecular changes due to the confinement. In this context, significant nutritional deficiencies with consequent molecular mechanism changes in the cells that induce to the onset of physiological and cognitive impairment have been considered.” This article is part of the Research Topic “Space (Nano)Medicine” (https://www.frontiersin.org/research-topics/18488/space-nanomedicine#articles). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.

 

2

Guarnieri S, Morabito C, Bevere M, Lanuti P, Mariggiò MA.

Oxid Med Cell Longev. 2021 Apr 20;2021:9951113.

Note: The Random Positioning Machine was used in this study. This article may be obtained online without charge.

 

3

Friedl-Werner A, Machado M-L, Balestra C, Liegard Y, Philoxene B, Brauns K, Stahn AC, Hitier M, Besnard S.

Front. Physiol. 2021 May 13;12(597).

Note: Parabolic flight results. From abstract: “We observed a deterioration in attentional processing prior to the first parabola that was further aggravated in weightlessness and returned to baseline after the last parabola. Reaction Time, Hit and False Alarm Rate were moderately correlated with self-reported anxiety state, but not cortisol levels or emotional states. The use of scopolamine had minor effects on Reaction Time. Our results confirm previous studies reporting impairments of cognitive performance in 0 g, and highlight important aspects that should be considered for the design of behavioral research experiments in future parabolic flight campaigns.” This article may be obtained online without charge.

 

4

Sun J, Yang H, Yang X, Chen X, Xu H, Shen Y, Ding F, Gu X, Zhu J, Sun H.

Ann Transl Med. 2021 Apr;9(8):643.

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

5

de Vries H, Khoury-Hanold W.

Front Psychol. 2021 Apr 26;12:582083. Review.

Note: This article may be obtained online without charge.

 

6

Barnard S, Uwineza A, Kalligeraki A, McCarron R, Kruse F, Ainsbury EA, Quinlan RA.

Radiat Res. 2021 May 13. Online ahead of print.

7

Gorbunov NV, Kiang JG.

Radiat Res. 2021 May 12. Online ahead of print.

8

McCarron RA, Barnard SGR, Babini G, Dalke C, Graw J, Leonardi S, Mancuso M, Moquet JE, Pawliczek D, Pazzaglia S, De Stefano I, Ainsbury EA.

Radiat Res. 2021 May 13. Online ahead of print.

9

Lian M, Sun B, Han Y, Yu B, Xin W, Xu R, Ni B, Jiang W, Hao Y, Zhang X, Shen Y, Qiao Z, Dai K.

Biomaterials. 2021 Jul 1;274:120841. Online ahead of print.

10

Moon RE, Mitchell SJ.

Undersea Hyperb Med. 2021 Second-Quarter;48(2):195-203.

11

Gapper KS, Stevens S, Antoni R, Hunt J, Allison SJ.

Int J Sports Med. 2021 May 11. Online ahead of print.

Note: This article may be obtained online without charge.

 

12

Asadi H, Monfared S, Athanasiadis DI, Stefanidis D, Yu D.

Ergonomics. 2021 May 11;1-14. Online ahead of print.

13

Wagoner JA, Dill KA.

Proc Natl Acad Sci USA. 2021 May 18;118(20):e2101871118.