NASA Spaceline Current Awareness List #928 11 December 2020 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Zschokke S, Countryman S, Cushing PE.
Spiders in space-orb-web-related behaviour in zero gravity.
Naturwissenschaften. 2021 Feb;108(1):1. Epub 2020 Dec 3.
https://pubmed.ncbi.nlm.nih.
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: 2.090
Funding: “Partial funding for the hardware development and implementation of the space flight experiment was received by BioServe Space Technologies at the University of Colorado via a supplemental award to cooperative agreement #NNJ10GA25A with NASA.”
2
Anderson MJ, Song Y, Fan H, Wright JG, Ren Z, Hua DH, Koehne JE, Meyyappan M, Li J.
Simultaneous, multiplex quantification of protease activities using a gold microelectrode array.
Biosens Bioelectron. 2020 Oct 1;165:112330.
https://pubmed.ncbi.nlm.nih.
PI: M.J. Anderson, TRISH Postdoctoral Fellowship Program
Journal Impact Factor: 10.257
Funding: “National Institute of Health (USA) under the award number R01 CA217657, the Johnson Cancer Research Center at Kansas State University (USA), and the Translational Research Institute for Space Health (USA) through Cooperative Agreement NNX16AO69A.”
3
Nicholson WL.
Spore‐forming bacteria as model organisms for studies in astrobiology.
In: Sechkbach J, Stan-Lotter H, eds. Extremophiles as Astrobiological Models. Beverly, MA: Scrivner, 2021. p. 275-90.
https://onlinelibrary.wiley.
Journal Impact Factor: Not applicable to this publication
Funding: “I wish to thank the NASA Exobiology, Astrobiology, and Mars Fundamental Research programs for their generous funding of this research.”
4
Hansen AB, Lawley JS, Rickards CA, Howden EJ, Sarma S, Cornwell WK 3rd, Amin SB, Mugele H, Marume K, Possnig C, Whitworth LA, Williams MA, Levine BD.
Reducing intracranial pressure by reducing central venous pressure: Assessment of potential countermeasures to spaceflight associated neuro-ocular syndrome.
J Appl Physiol (1985). 2020 Dec 3. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PI: B.D. Levine
Note: Thigh cuffs and breathing through an Impedance Threshold Device were used.
Journal Impact Factor: 3.044
Funding: “This work was supported by the National Space Biomedical Research Institute through NCC 9-58.”
5
Krause AR, Speacht TA, Steiner JL, Lang CH, Donahue HJ.
Mechanical loading recovers bone but not muscle lost during unloading.
npj Microgravity. 2020 Dec 3;6(1):36.
https://www.nature.com/
PI: H.J. Donahue
Note: Hindlimb unloading study. This article may be obtained online without charge.
Journal Impact Factor: 3.380
Funding: “This work was supported by National Space Biomedical Research Institute grant MA02802, and NIH grant R01AG13097.”
6
Scott JM, Downs M, Buxton R, Goetchius E, Crowell B, Ploutz-Snyder R, Hackney KJ, Ryder J, English K, Ploutz-Snyder LL.
Disuse-induced muscle loss and rehabilitation: The National Aeronautics and Space Administration bed rest study.
Crit Care Explor. 2020 Dec;2(12):e0269.
https://pubmed.ncbi.nlm.nih.
PI: L.L. Ploutz-Snyder
Note: Bed rest study. The study was part of Clinical Trial NCT00891449: Space Flight Simulation to Study Effects of Micro-gravity Through Bed Rest (Flight Analogs Project). This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: “Supported, in part, by the Human Research Program of the National Aeronautics and Space Administration and National Space Biomedical Research Institute (NNJ11ZSA002N). Dr. Scott is supported by research grants from AKTIV Against Cancer and the Memorial Sloan Kettering Cancer Center Support Grant/Core Grant (P30 CA008748).”
7
Paladini MS, Feng X, Krukowski K, Rosi S.
Microglia depletion and cognitive functions after brain injury: From trauma to galactic cosmic ray.
Neurosci Lett. 2020 Nov 28. [Epub ahead of print] Review.
https://pubmed.ncbi.nlm.nih.
PI: S. Rosi; S. Rosi/VNSCOR
Journal Impact Factor: 2.274
Funding: “This work was supported by the National Institutes of Health: NIH/National Institute on Aging Grant R01AG056770 (to S.R.); NIH/National Cancer Institute Grants R01 CA213441 and R01 CA246722 (to S. R.), National Aeronautic Space Agency NASA grants NNX14AC94G and 80NSSC19K1581 (to S.R.).”
8
Allison KC, Hopkins CM, Ruggieri M, Spaeth AM, Ahima RS, Zhang Z, Taylor DM, Goel N.
Prolonged, controlled daytime versus delayed eating impacts weight and metabolism.
Curr Biol. 2020 Nov 20. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PI: N. Goel
Note: This article may be obtained online without charge.
Journal Impact Factor: 9.60
Funding: “This research was supported by NIH grants R21 DK100787 and R01 DK117488. Inpatient services at the Center for Human Phenomic Science were supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health, through grant UL1TR000003. Additional support was from National Aeronautics and Space Administration (NASA) grants NNX14AN49G and 80NSSC20K0243. R.S.A. was supported by a Bloomberg Distinguished Professorship.”
9
McHill AW, Hilditch CJ, Fischer D, Czeisler CA, Garaulet M, Scheer F, Klerman EB.
Stability of the timing of food intake at daily and monthly timescales in young adults.
Sci Rep. 2020 Nov 30;10(1):20849.
https://pubmed.ncbi.nlm.nih.
PIs: E.B. Klerman, D. Schreckenghost
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.998
Funding: “NIH (Grants K01HL146992, F32DK107146, T32HL007901, K24HL105664, R01HL114088, R01GM105018, R01HL128538, P01AG009975, R21HD086392, R01 DK099512, R01 HL140574) and NSBRI (Grants HFP02802, HFP04201, HDP0006). This work has been supported in part by The Spanish Government of Investigation, Development and Innovation (SAF2017-84135-R) including FEDER co-funding; The Autonomous Community of the Region of Murcia through the Seneca Foundation (20795/PI/18) and NIDDK R01DK105072 granted to M. Garaulet.”
10
St Hilaire MA, Lammers-van der Holst HM, Chinoy ED, Isherwood CM, Duffy JF.
Prediction of individual differences in circadian adaptation to night work among older adults: Application of a mathematical model using individual sleep-wake and light exposure data.
Chronobiol Int. 2020;37(9-10):1404-11.
https://pubmed.ncbi.nlm.nih.
PI: M.A. St. Hilaire
Note: The article is part of a special issue that contains selected papers from the 24th International Symposium on Shiftwork and Working Time (Shiftwork2019).
Journal Impact Factor: 2.486
Funding: “This work was supported by the National Center for Advancing Translational Sciences [TR001102]; National Heart, Lung, and Blood Institute [T32 HL007901]; National Institute on Aging [R01 AG044416]; National Institutes of Health [R21 NR018974]; NASA [80NSSC20K0576].”
11
Yamazaki EM, Antler CA, Lasek CR, Goel N.
Residual, differential neurobehavioral deficits linger after multiple recovery nights following chronic sleep restriction or acute total sleep deprivation.
Sleep. 2020 Nov 6. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PI: N. Goel
Journal Impact Factor: 4.805
Funding: “This work was primarily supported by the Department of the Navy, Office of Naval Research (Award No. N00014-11-1-0361 to N.G). Other support provided by the National Aeronautics and Space Administration (NASA) NNX14AN49G and grant 80NSSC20K0243 (to N.G.), National Institutes of Health (NIH) grant R01DK117488 (to N.G.), and Clinical and Translational Research Center grant (UL1TR000003).”
______________________________
Other papers of interest:
1
Kuznetsov MS, Valiullin VV, Lisyukov AN, Koshpaeva ES, Saitov VR, Razvina OS, Hayatsu M, Ushiki T, Islamov RR.
Possible mechanisms of axonal transport disturbances in mouse spinal motoneurons induced by hypogravity.
Bull Exp Biol Med. 2020 Dec;170(2):264-7.
https://pubmed.ncbi.nlm.nih.
Note: Bion-M1 results.
2
Dullin C, di Lillo F, Svetlove A, Albers J, Wagner W, Markus A, Sodini N, Dreossi D, Alves F, Tromba G.
Multiscale biomedical imaging at the SYRMEP beamline of Elettra – Closing the gap between preclinical research and patient applications.
Physics Open. 2020 Dec 3. [Article in Press]
http://www.sciencedirect.com/
Note: ISS results. The second section of the paper explores the effects of microgravity on bone structure. This article may be obtained online without charge.
3
Zhivodernikov IV, Ratushnyy AY, Matveeva DK, Buravkova LB.
Extracellular matrix proteins and transcription of matrix-associated genes in mesenchymal stromal cells during modeling of the effects of microgravity.
Bull Exp Biol Med. 2020 Dec;170(2):230-2.
https://pubmed.ncbi.nlm.nih.
Note: The method of microgravity simulation is not provided in the available abstract. The article is translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, 2020 Aug;170(8):201-4.
4
Yu X, Xu J, Liu W, Zhang Z, He C, Xu W.
Protective effects of pulmonary surfactant on decompression sickness in rats.
J Appl Physiol (1985). 2020 Dec 3. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
5
Lancaster SM, Sanghi A, Wu S, Snyder MP.
A customizable analysis flow in integrative multi-omics.
Biomolecules. 2020 Nov 27;10(12):E1606. Review.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
6
Alves PKN, Cruz A, Silva WJ, Labeit S, Moriscot AS.
Leucine supplementation decreases HDAC4 expression and nuclear localization in skeletal muscle fiber of rats submitted to hindlimb immobilization.
Cells. 2020 Dec 2;9(12):E2582.
https://pubmed.ncbi.nlm.nih.
Note: Hindlimb unloading study. This article may be obtained online without charge.
7
Fournier R, Harrison RE.
Strategies for studying bone loss in microgravity.
REACH. 2020 Dec 8. [Article in Press] Review.
http://www.sciencedirect.com/
Note: The review examines research performed using the International Space Station, un-crewed satellites, head-down tilt bed rest, rodent hindlimb unloading, and 2D/3D clinorotation cell culture systems.
8
Popp KL, Ackerman KE, Rudolph SE, Johannesdottir F, Hughes JM, Tenforde AS, Bredella MA, Xu C, Unnikrishnan G, Reifman J, Bouxsein ML.
Changes in volumetric bone mineral density over 12 months after a tibial bone stress injury diagnosis: Implications for return to sports and military duty.
Am J Sports Med. 2020 Dec 1. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
9
Beach T, Authier S, Javitz HS, Wong K, Bakke J, Gahagen J, Bunin DI, Chang PY.
Total body irradiation models in NHPs – Consideration of animal sex and provision of supportive care to advance model development.
Int J Radiat Biol. 2020 Dec 1.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
10
Paithankar JG, Sandu Ghodke T, Patil RK.
Insight into the evolutionary profile of radio-resistance among insects having intrinsically evolved defence against radiation toxicity.
Int J Radiat Biol. 2020 Dec 2. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
11
Grant EJ, Yamamura M, Brenner AV, Preston DL, Utada M, Sugiyama H, Sakata R, Mabuchi K, Ozasa K.
Radiation risks for the incidence of kidney, bladder and other urinary tract cancer: 1958-2009.
Radiat Res. 2020 Dec 2. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
12
Nakano H, Kawahara D, Tanabe S, Utsunomiya S, Takizawa T, Sakai M, Saito H, Ohta A, Kaidu M, Ishikawa H.
Radiobiological effects of the interruption time with Monte Carlo Simulation on multiple fields in photon beams.
J Appl Clin Med Phys. 2020 Dec 3. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
13
Ung MC, Garrett L, Dalke C, Leitner V, Dragosa D, Hladik D, Neff F, Wagner F, Zitzelsberger H, Miller G, Hrabě de Angelis M, Rößler U, Vogt Weisenhorn D, Wurst W, Graw J, Hölter SM.
Dose-dependent long-term effects of a single radiation event on behaviour and glial cells.
Int J Radiat Biol. 2020 Dec 2. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
14
Irmak T, Pool DM, Happee R.
Objective and subjective responses to motion sickness: The group and the individual.
Exp Brain Res. 2020 Nov 29. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
15
Smyth J, Birrell S, Woodman R, Jennings P.
Exploring the utility of EDA and skin temperature as individual physiological correlates of motion sickness.
Appl Ergon. 2021 Apr;92:103315. Epub 2020 Dec 1.
https://pubmed.ncbi.nlm.nih.
Note: The treatment of motion sickness with Electrodermal Activity is discussed.
16
Šolcová I, Vinokhodova AG, Gushin V.
Anticipated and perceived personal growth and values in two spaceflight simulation studies.
Acta Astronaut. 2021 Feb;179:561-8. Epub 2020 Dec 3.
http://www.sciencedirect.com/
Note: Results are from the SIRIUS-17 and -19 ground-based isolation missions.
17
Cazzaniga A, Ille F, Wuest S, Haack C, Koller A, Giger-Lange C, Zocchi M, Egli M, Castiglioni S, Maier JA.
Scalable microgravity simulator used for long-term musculoskeletal cells and tissue engineering.
Int J Mol Sci. 2020 Nov 24;21(23):E8908.
https://pubmed.ncbi.nlm.nih.
Note: From the Introduction: “Here, we describe a novel microgravity simulator (MGS) that evolved from the well-known RPM principle. With our new MGS, we resolve some essential drawbacks of the classical RPM, thus improving substantially the overall quality of simulated microgravity cultivation.” This article may be obtained online without charge.
18
Moulton DE, Oliveri H, Goriely A.
Multiscale integration of environmental stimuli in plant tropism produces complex behaviors.
Proc Natl Acad Sci U S A. 2020 Dec 3. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
19
Mahadevan K, Cowan E, Kalsi N, Bolam H, Arnett R, Hobson A, Guha K, Morton G, Brennan PA, Kalra PR.
Distractions in the cardiac catheterisation laboratory: Impact for cardiologists and patient safety.
Open Heart. 2020 Dec;7(2):e001260.
https://pubmed.ncbi.nlm.nih.
Note: The NASA Task Load Index was used. This article may be obtained online without charge.
20
Toy S, Miller CR, Daly Guris RJ, Duarte SS, Koessel S, Schiavi A.
Evaluation of 3 cognitive load measures during repeated simulation exercises for novice anesthesiology residents.
Simul Healthc. 2020 Dec;15(6):388-96.
https://pubmed.ncbi.nlm.nih.
Note: The NASA Task Load Index was used.
21
Whittington P, Dogan H, Phalp K, Jiang N.
Detecting physical abilities through smartphone sensors: An assistive technology application.
Disabil Rehabil Assist Technol. 2020 Dec 1. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: The NASA Task Load Index was used.
