NASA Spaceline Current Awareness List #923 6 November 2020 (Space Life Science Research Results)
SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/
Papers deriving from NASA support:
1
Turner RT, Branscum AJ, Wong CP, Iwaniec UT, Morey-Holton E.
Studies in microgravity, simulated microgravity and gravity do not support a gravitostat.
J Endocrinol. 2020 Dec;247(3):191-200. Epub 2020 Oct 28.
https://pubmed.ncbi.nlm.nih.
PI: R.T. Turner
Note: Space Shuttle and Bion 4 results. Hindlimb unloading was used in ground studies.
Journal Impact Factor: 4.04
Funding: “This work was supported by NASA (80NSSC19K0430 and NNX15AL15G).”
2
Daudu R, Singh NK, Wood JM, Debieu M, O’Hara NB, Mason CE, Venkateswaran K.
Draft genome sequences of Bacillaceae strains isolated from the International Space Station.
Microbiol Resour Announc. 2020 Oct 29;9(44):e00701-20.
https://pubmed.ncbi.nlm.nih.
PI: K. Venkateswaran
Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: 0.88
Funding: “Part of the research described in this publication was carried out at the Jet Propulsion Laboratory (JPL), California Institute of Technology, under a contract with NASA. Government sponsorship is acknowledged. This research was funded by a 2012 Space Biology NNH12ZTT001N grant (no. 19-12829-26) under task order NNN13D111T award to K.V., which also funded a postdoctoral fellowship for J.M.W., a JPL graduate fellowship to R.D., and a subcontract to Biotia, Inc.”
3
Lecheler L, Paulke F, Sonnow L, Limper U, Schwarz D, Jansen S, Klussmann JP, Tank J, Jordan J.
Gravity and mastoid effusion.
Am J Med. 2020 Oct 25. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: Bed rest study (AGBRESA is the Artificial Gravity Bed Rest—European Space Agency). A short-arm human centrifuge was used.
Journal Impact Factor: 4.529
Funding: “National Aeronautics and Space Administration (NASA), European Space Agency (ESA).”
4
Schwendner P, Jobson ME, Schuerger AC.
Addition of anaerobic electron acceptors to solid media did not enhance growth of 125 spacecraft bacteria under simulated low-pressure Martian conditions.
Sci Rep. 2020 Oct 26;10(1):18290.
https://pubmed.ncbi.nlm.nih.
Note: Bacteria studied were recovered during prelaunch activities from six authentic Mars spacecraft including the Viking, Pathfinder, Spirit, Opportunity, Phoenix, InSight, and Curiosity platforms. This article may be obtained online without charge.
Journal Impact Factor: 4.011
Funding: “We are also grateful to NASA’s Planetary Protection Office (Grant 80NSSC17K0263) and the University of Central Florida (Grant UCF01-0000381921) for providing the funding for the project. Furthermore, we would like to thank the Florida Space Grant Consortium for providing support for coauthor MEJ as a 2018 summer student intern.”
5
Urbaniak C, Mhatre S, Grams T, Parker C, Venkateswaran K.
Validation of the International Space Station Smart Sample Concentrator for microbial monitoring of low biomass water samples.
J Biomol Tech. 2020 Oct 16. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
Journal Impact Factor: 2.18
Funding: “The research described in this manuscript was funded by the International Space Station Advanced Exploration Systems program and Life Support System award to K.V., which also funded S.M., C.P., and C.U. The iSSC prototype was supported through NASA Contracts NNX15CP23P, NNX16CP10C, and 80NSSC19C0023 to InnovaPrep, a Small Business Innovative Research company.”
6
Silverman JD, Roche K, Mukherjee S, David LA.
Naught all zeros in sequence count data are the same.
Comput Struct Biotechnol J. 2020 Sep 28;18:2789-98. Review.
https://pubmed.ncbi.nlm.nih.
PI: L.A. David
Note: This article may be obtained online without charge.
Journal Impact Factor: 6.018
Funding: “JDS and LAD were supported in part by the Duke University Medical Scientist Training Program (GM007171), the Global Probiotics Council, a Searle Scholars Award, the Hartwell Foundation, an Alfred P. Sloan Research Fellowship, the Translational Research Institute through Cooperative Agreement NNX16AO69A, the Damon Runyon Cancer Research Foundation, the Hartwell Foundation, and NIH 1R01DK116187-01. SM and KR would like to acknowledge the support of grants NSF IIS-1546331, NSF DMS-1418261, NSF IIS-1320357, NSF DMS-1045153, and NSF DMS1613261.”
7
Barger LK, Sullivan JP, Lockley SW, Czeisler CA.
Exposure to short wavelength-enriched white light and exercise improves alertness and performance in operational NASA flight controllers working overnight shifts.
J Occup Environ Med. 2020 Oct 14. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
PIs: C.A. Czeisler, S.W. Lockley
Note: Study participants were NASA flight controllers working during overnight shifts.
Journal Impact Factor: 1.644
Funding: “The study was supported by NASA cooperative agreement NNX10AF47G. Drs. Barger, Czeisler and Lockley received support from the National Space Biomedical Research Institute (HFP0160, HFP02801) through NASA NCC 9-58. Dr. Barger was supported in part by the National Institute of Occupational Safety and Health (R01 OH01300 and R01 OH011773) and was a prior recipient of the National Heart, Lung and Blood Institute fellowships in the program of training in Sleep, Circadian and Respiratory Neurobiology at Brigham and Women’s Hospital (NHLBI; T32 HL079010).”
8
Traylor AM, Tannenbaum SI, Thomas EJ, Salas E.
Helping healthcare teams save lives during COVID-19: Insights and countermeasures from team science.
Am Psychol. 2020 Oct 29. [Epub ahead of print] Review.
https://pubmed.ncbi.nlm.nih.
PIs: C.S. Burke, M.A. Rosen
Note: This article may be obtained online without charge.
Journal Impact Factor: 6.536
Funding: “This work was partially supported by the Center for Clinical and Translational Sciences (University of Texas Health Science Center, Houston, Texas), which is funded by the National Institutes of Health (Clinical and Translational Award UL1 TR003167) from the National Center for Advancing Translational Sciences…This work was also partially supported by the National Science Foundation (Grants 1853528 and 1842894) to Rice University as well as the National Aeronautics and Space Administration (Grants NNX16AP96G and NNX17AB55G) to Rice University.”
9
Vu LQ, Kim H, Schulze LJH, Rajulu SL.
Evaluating lumbar shape deformation with fabric strain sensors.
Hum Factors. 2020 Oct 29. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.165
Funding: “This study was partially funded by NASA HHPC NNJ15HK11B, USA.”
10
Burian BK, Dismukes RK.
Why we fail to rescue during critical events.
Anesthesiol Clin. 2020 Dec;38(4):727-43. Review. Epub 2020 Nov 1.
https://pubmed.ncbi.nlm.nih.
Journal Impact Factor: Not available for this journal
Funding: The authors are affiliated with NASA Ames Research Center.
11
Patel ZS, Brunstetter TJ, Tarver WJ, Whitmire AM, Zwart SR, Smith SM, Huff JL.
Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars.
npj Microgravity. 2020 Nov 5;6(1):33. Review.
https://www.nature.com/
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.380
Funding: “This review was supported in part by a grant to Dr. Patel from the Translational Research Institute for Space Health (TRISH) from the Baylor College of Medicine (The Red Risk School). It was also supported by funding through NASA Human Health and Performance Contract #NNJ15HK11B (Z.S.P., S.R.Z., J.L.H.) and NASA directly (T.J.B., W. J.T., A.M.W., S.M.S., J.L.H.).”
12
Min J, Sempionatto JR, Teymourian H, Wang J, Gao W.
Wearable electrochemical biosensors in North America.
Biosens Bioelectron. 2021 Jan 15;172:112750. Epub 2020 Oct 26.
https://pubmed.ncbi.nlm.nih.
PI: W. Gao
Journal Impact Factor: 10.257
Funding: “This work was supported by National Institutes of Health grant 5R21NR018271 the Translational Research Institute for Space Health through NASA NNX16AO69A, NASA Cooperative Agreement 80NSSC20M0167 (Caltech) and the Center of Wearable Sensors at University of California San Diego (UCSD).”
13
Douglas GL, Massa GD, Hummerick ME, Hintze PE.
Cold plasma to disinfect spaceflight grown produce.
In: Bermudez-Aguirre D, ed. Advances in Cold Plasma Applications for Food Safety and Preservation. Cambridge, MA: Academic Press, 2020. p. 333-40.
http://www.sciencedirect.com/
Journal Impact Factor: Not applicable to this publication
Funding: No funding cited. G.L. Douglas is affiliated with NASA Johnson Space Center; G.D. Massa, M.E. Hummerick, and P.E. Hintze are affiliated with NASA Kennedy Space Center.
Please Note: A two-volume set of books, Psychology and Human Performance in Space Programs, is available from Routledge/CRC Press. Edited by Lauren Blackwell Landon, Kelly J. Slack, and Eduardo Salas, the books summarize available knowledge, tools, and techniques, and identify areas for future research needed to protect humans in space. Volume 1 is listed here; Volume 2 will be included in next week’s SPACELINE Current Awareness List.
14
Landon LB, Slack KJ, Salas E. (eds.)
Psychology and Human Performance in Space Programs: Research at the Frontier.
Boca Raton, FL: CRC Press, 2020. 331 p.
https://www.taylorfrancis.com/
PI: E. Salas
Journal Impact Factor: Not applicable to this publication or the following chapters
Funding: “Lauren Blackwell Landon is supported by KBR’s Human Health and Performance Contract NNJ15HK11B through the National Aeronautics and Space Administration. Eduardo Salas is supported in part by grants NNX16AP96G and NNX16AB08G from the National Aeronautics and Space Administration (NASA) to Rice University, and grant NNX17AB55G from NASA to Johns Hopkins University School of Medicine and Rice University.”
15
Schorn JM, Roma PG.
Physical hazards of space exploration and the biological bases of behavioral health and performance in extreme environments.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 1-22.
https://www.taylorfrancis.com/
PI: P.G. Roma
Funding: “JMS and PGR are supported by KBR’s Human Health and Performance Contract NNJ15HK11B through the National Aeronautics and Space Administration. JMS and PGR are also supported in part by NASA Human Research Program Directed Project CBS Operational Performance Measures (P. G. Roma, PI), and JMS is supported in part by UCLA’s Graduate Research Mentorship Fellowship.”
16
Cromwell RL, Neigut J.
Spaceflight research on the ground: Managing analogs for behavioral health research.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 23-46.
https://www.taylorfrancis.com/
Funding: No funding cited. The authors are affiliated with NASA Johnson Space Center.
17
Bell ST, Roma PG, Caldwell BJ.
Special considerations for conducting research in mission-simulation analog environments: Challenges, solutions, and what is needed.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 47-66.
https://www.taylorfrancis.com/
PIs: S.T. Bell, N. Contractor
Funding: “Work related to this project conducted by STB was supported by National Aeronautics and Space Administration grants NNX16AQ48G, NNX15AM32G, NNJ15HK18P, and NNJ13HF07P. STB, PGR, and BJC were supported by KBR’s Human Health and Performance Contract NNJ15HK11B through the National Aeronautics and Space Administration.”
18
Driskell JE, Salas E, Driskell T.
Research in extreme real-world environments: Challenges for spaceflight operations.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 67-86.
https://www.taylorfrancis.com/
Funding: No funding cited. E. Salas is the recipient of a number of NASA grants related to team psychology in long duration spaceflight.
19
Kazi S, Khaleghzadegan S, Rosen MA.
Technological advances to understand and improve individual and team resilience in extreme environments.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 87-106.
https://www.taylorfrancis.com/
PI: M.A. Rosen
Funding: “This work was partially funded by a grant from the National Aeronautics and Space Administration (Grant# NNX17AB55G; PI: Rosen).”
20
Antone B, Lungeanu A, Bell ST, DeChurch LA, Contractor N.
Computational modeling of long-distance space exploration: A guide to predictive and prescriptive approaches to the dynamics of team composition.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 107-30.
https://www.taylorfrancis.com/
PI: N. Contractor
Funding: “The material is based upon work supported by NASA under award No. NNX15AM32G.”
21
Kole JA, Healy AF, Schneider VI, Barshi I.
Training principles for declarative and procedural tasks.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 131-50.
https://www.taylorfrancis.com/
Funding: No funding cited. I. Barshi is affiliated with NASA Ames Research Center.
22
Maynard MT, Kennedy DM, Tannenbaum SI, Mathieu JE, Levy JH.
Team adaptation and resilience: Where the literature currently stands and how it applies to long-duration isolated, confined, and extreme contexts.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 151-70.
https://www.taylorfrancis.com/
Funding: No funding cited. S.I. Tannenbaum is the recipient of a NASA grant related to team resilience.
23
Burke CS, Moavero J, Feitosa J.
Toward an understanding of training requirements for multicultural teams in long-duration spaceflight.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 171-94.
https://www.taylorfrancis.com/
Funding: No funding cited. C.S. Burke is the recipient of a NASA grant related to team diversity.
24
Paoletti J, Kilcullen MP, Salas E.
Teamwork in space exploration.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 195-216.
https://www.taylorfrancis.com/
PIs: E. Salas, C.S. Burke, M.A. Rosen
Funding: “This work was supported in part by grants NNX16AP96G and NNX16AB08G from National Aeronautics and Space (NASA) to Rice University. This work was also supported by grant NNX17AB556G from NASA to Rice University via Johns Hopkins University (Michael Rosen, P.I.).”
25
Landon LB, Paoletti J.
Extreme roommates: Exploring group-living skills as a unique team skill area.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 217-36.
https://www.taylorfrancis.com/
Funding: No funding cited. L.B. Landon is affiliated with NASA Johnson Space Center.
26
Pendergraft JG, Carter DR, Trainer HM, Jones JM, Schecter A, Shuffler ML, DeChurch LA, Contractor NS.
Supporting spaceflight multiteam systems throughout long-duration exploration missions: A countermeasure toolkit.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 237-57.
https://www.taylorfrancis.com/
Funding: No funding cited. D.R. Carter, N. Contractor, and L.A. DeChurch are the recipients of NASA funding related to team systems.
27
Holden K, Marquez JJ, Vos G, Cross EV 2nd.
Human interaction with space-based systems.
In: Landon LB, Slack KJ, Salas E, eds. Psychology and Human Performance in Space Programs: Research at the Frontier. Boca Raton, FL: CRC Press, 2020. p. 259-94.
https://www.taylorfrancis.com/
Funding: “The research described in this chapter was funded by the NASA Human Research Program (HRP), NASA Extravehicular Activity (EVA) Program, and Orion Multi-Purpose Crew Vehicle (MPCV) Program. Except as cited otherwise, work was performed by civil servants and contractors as part of the Human Health and Performance Contract NNJ15HK11B (or former Bioastronautics Contract NAS9-02078) through the National Aeronautics and Space Administration.”
______________________________
Other papers of interest:
1
Ott E, Kawaguchi Y, Kölbl D, Rabbow E, Rettberg P, Mora M, Moissl-Eichinger C, Weckwerth W, Yamagishi A, Milojevic T.
Molecular repertoire of Deinococcus radiodurans after 1 year of exposure outside the International Space Station within the Tanpopo mission.
Microbiome. 2020 Oct 29;8(1):150.
https://pubmed.ncbi.nlm.nih.
Note: ISS results. This article may be obtained online without charge.
2
Iwasaki KI, Ogawa Y, Kurazumi T, Imaduddin SM, Mukai C, Furukawa S, Yanagida R, Kato T, Konishi T, Shinojima A, Levine BD, Heldt T.
Long-duration spaceflight alters estimated intracranial pressure and cerebral blood velocity.
J Physiol. 2020 Oct 25. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: ISS results. From the Methods section: “The research study was registered at the NASA Life Science Data Archive (#13390, https://lsda.jsc.nasa.gov/
3
Jirak P, Wernly B, Lichtenauer M, Franz M, Knost T, Abusamrah T, Kelm M, Bimpong-Buta NY, Jung C.
Next-generation sequencing analysis of circulating micro-RNA expression in response to parabolic flight as a spaceflight analogue.
npj Microgravity. 2020 Nov 2;6(1):31.
https://www.nature.com/
Note: Parabolic flight results. This article may be obtained online without charge.
4
Hinkelbein J, Kerkhoff S, Adler C, Ahlbäck A, Braunecker S, Burgard D, Cirillo F, De Robertis E, Glaser E, Haidl TK, Hodkinson P, Iovino IZ, Jansen S, Johnson KVL, Jünger S, Komorowski M, Leary M, Mackaill C, Nagrebetsky A, Neuhaus C, Rehnberg L, Romano GM, Russomano T, Schmitz J, Spelten O, Starck C, Thierry S, Velho R, Warnecke T.
Cardiopulmonary resuscitation (CPR) during spaceflight – A guideline for CPR in microgravity from the German Society of Aerospace Medicine (DGLRM) and the European Society of Aerospace Medicine Space Medicine Group (ESAM-SMG).
Scand J Trauma Resusc Emerg Med. 2020 Nov 2;28(1):108.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
5
Alauzet C, Cunat L, Wack M, Lanfumey L, Legrand-Frossi C, Lozniewski A, Agrinier N, Cailliez-Grimal C, Frippiat JP.
Impact of a model used to simulate chronic socio-environmental stressors encountered during spaceflight on murine intestinal microbiota.
Int J Mol Sci. 2020 Oct 23;21(21):E7863.
https://pubmed.ncbi.nlm.nih.
Note: Mice were exposed to “multiple unpredictable mild environmental and psychosocial stressors, to simulate chronic socio-environmental stresses encountered during a spaceflight and explore their effects on gut microbiota composition.” This article may be obtained online without charge.
6
Mirzoev TM.
Skeletal muscle recovery from disuse atrophy: Protein turnover signaling and strategies for accelerating muscle regrowth.
Int J Mol Sci. 2020 Oct 26;21(21):E7940. Review.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
7
Slysz JT, Boston M, King R, Pignanelli C, Power GA, Burr JF.
Blood flow restriction combined with electrical stimulation attenuates thigh muscle disuse atrophy.
Med Sci Sports Exerc. 2020 Oct 22. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: Unilateral leg unloading was used.
8
Wright TJ, Davis RW, Holser RR, Hückstädt LA, Danesi CP, Porter C, Widen SG, Williams TM, Costa DP, Sheffield-Moore M.
Changes in Northern elephant seal skeletal muscle following thirty days of fasting and reduced activity.
Front Physiol. 2020 Oct 6;11:564555.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
9
Blázquez-Carmona P, Mora-Macías J, Morgaz J, Fernández-Sarmiento JA, Domínguez J, Reina-Romo E.
Mechanobiology of bone consolidation during distraction osteogenesis: Bone lengthening vs. bone transport.
Ann Biomed Eng. 2020 Oct 27. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
10
Sahbani K, Shultz LC, Cardozo CP, Bauman WA, Tawfeek HA.
Absence of αβ T cells accelerates disuse bone loss in male mice after spinal cord injury.
Ann N Y Acad Sci. 2020 Oct 26. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
11
Bolsunovsky A, Trofimova E, Dementyev D, Petrichenkov M.
The long-term effects of γ-radiation on the growth of Allium cepa plants.
Int J Radiat Biol. 2020 Oct 30. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
12
Tan S, Pei W, Huang H, Zhou G, Hu W.
Additive effects of simulated microgravity and ionizing radiation in cell death, induction of ROS and expression of RAC2 in human bronchial epithelial cells.
npj Microgravity. 2020 Nov 5;6(1):34.
https://www.nature.com/
Note: A 3-D clinostat was used. This article may be obtained online without charge.
13
Polymeropoulos VM, Czeisler M, Gibson MM, Anderson AA, Miglo J, Wang J, Xiao C, Polymeropoulos CM, Birznieks G, Polymeropoulos MH.
Tradipitant in the treatment of motion sickness: A randomized, double-blind, placebo-controlled study.
Front Neurol. 2020 Sep 29;11:563373.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
14
Danz A, Angelaki DE, DeAngelis GC.
The effects of depth cues and vestibular translation signals on the rotation tolerance of heading tuning in macaque area MSTd.
eNeuro. 2020 Oct 30. [Epub ahead of print]
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
15
Chellappa SL, Morris CJ, Scheer F.
Circadian misalignment increases mood vulnerability in simulated shift work.
Sci Rep. 2020 Oct 29;10(1):18614.
https://pubmed.ncbi.nlm.nih.
Note: This article may be obtained online without charge.
16
Bhandari DD, Brandizzi F.
Plant endomembranes and cytoskeleton: Moving targets in immunity.
Curr Opin Plant Biol. 2020 Dec;58:8-16. Epub 2020 Oct 21.
https://pubmed.ncbi.nlm.nih.
17
Makino Y, Ichinose K, Yoshimura M, Kawahara Y, Yuge L.
Efficient preservation of sprouting vegetables under simulated microgravity conditions.
PLoS One. 2020 Oct 15;15(10):e0240809.
https://pubmed.ncbi.nlm.nih.
Note: Rotation was used. This article may be obtained online without charge.
